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1321
The mediating role of social support in self-management and quality of life in patients with liver cirrhosis
Published 2025-02-01“…Data were analyzed using SPSS and PROCESS software. (1) Patients in the decompensated stage of liver cirrhosis and those classified in Child–Pugh class B/C had lower scores in self-management, quality of life, and social support compared to patients in the compensated stage of liver cirrhosis and those classified in Child–Pugh Class A. (2) Quality of life was positively correlated with both social support and self-management (r = 0.668, r = 0.665, both P < 0.001). (3) Mediation analysis showed that self-management had a direct predictive effect on quality of life. …”
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1322
Short communication: Genomic prediction based on unbiased estimation of the genomic relationship matrix in pigs
Published 2025-02-01“…In the simulated dataset, VanRaden2 method and the UKin+VanRaden1 method achieved relatively higher prediction accuracies, averaging 0.561 and 0.558 for the six traits, respectively. …”
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1323
Adipose tissue-derived microRNA-450a-5p induces type 2 diabetes mellitus by downregulating DUSP10
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1324
Lunar and Martian gravity alter immune cell interactions with endothelia in parabolic flight
Published 2025-02-01“…Expression levels of the adhesion markers Mac-1 on THP-1 cells as well as ICAM-1 on HUVECs were found elevated in lunar and Martian gravity, which was aggravated by TNF. …”
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1325
Mechanistic insights into 5-aminolevulinic acid photodynamic therapy for acne vulgaris: targeting lipogenesis via the OLR1-Wnt/β-catenin pathway
Published 2025-02-01“…Our findings revealed that ALA-PDT significantly reduces lipogenesis by upregulating OLR1, which in turn suppresses the SREBP1-FAS axis, thereby decreasing lipid accumulation in sebocytes. …”
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1326
Screen of propionate-producing probiotic strains in attenuating murine colitis by modulating immune response and restoring the intestinal barrier
Published 2025-02-01Subjects: Get full text
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1327
The effects of maternal health literacy, family functioning and self-efficacy on antepartum depression in pregnant women in China: a moderated mediation model
Published 2025-02-01“…The model indicated that FF had the strongest correlation with AD (β = -0.276, p < 0.01), followed by MHL (β = -0.248, p < 0.01) and self-efficacy (SE) (β = -0.222, p < 0.01). …”
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1328
GmERF57 negatively regulates root development and phosphate absorption in soybean
Published 2025-03-01“…We further uncovered that GmERF57 physically interacts with GmTUB1 (β-tubulin protein) and modulates soybean root architecture and Pi uptake capacity by downregulating GmTUB1 and other Pi starvation response genes. …”
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1329
Subwavelength-scale off-axis optical nanomanipulation within Gaussian-beam traps
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1330
Off-the-shelf CAR-NK cells targeting immunogenic cell death marker ERp57 execute robust antitumor activity and have a synergistic effect with ICD inducer oxaliplatin
Published 2024-07-01“…Here, we explore whether immunogenic cell death (ICD) marker ERp57 translocated from endoplasmic reticulum to cell surface after drug treatment could be used as a target for CAR-NK therapy.Methods To target ERp57, a VHH phage display library was used for screening ERp57-targeted nanobodies (Nbs). …”
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1331
Breaking the biofilm barrier: Juglone derivatives as dual-action inhibitors and anti-quorum sensing agents
Published 2025-02-01“…High Performance Liquid Chromatography (HPLC) was performed to analyze the acyl homoserine lactones (AHLs) signals degradation by juglone derivatives. …”
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1332
Freshwater fungi in the karst plateau wetlands from Guizhou Province, China: taxonomic novelties in Melanommataceae (Pleosporales)
Published 2025-02-01“…Phylogenetic analyses using ITS, LSU, SSU, and tef-1α gene regions have revealed the placements of these isolates in Melanommataceae (Pleosporales, Dothideomycetes). …”
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1333
Clinical and molecular analysis of JCPyV and BKPyV infection and associated risk of urothelial carcinoma development in the upper tract
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1334
Oncological outcomes following extreme oncoplastic breast conserving surgery (eOPBCS) for locally advanced breast cancer (LABC): A systematic review and meta-analysis
Published 2025-02-01“…Meanwhile, HRs for DFS (1.11, 95% CI 0.60-2.08) and LRR (0.67, 95% CI 0.38-1.18) showed that there were no statistically significant differences but a trend toward lower recurrence rates with mastectomy. …”
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1335
Critical band-to-band-tunnelling based optoelectronic memory
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1336
Efficacy of Adjunctive Antiseptic Lavage Solution in Managing Acute Hip/Knee Prosthetic Joint Infection: A Comparative Study in a Tertiary Revision Center
Published 2025-02-01“…Subgroup analysis demonstrated no difference in knee DAIRs (P = .761) but a trend toward significance in hip DAIRs (P = .262). …”
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1337
The effect of GM-CSF and predictors of treatment outcome in pediatric septic shock patients
Published 2025-02-01“…The initial comparison showed a higher 28-day mortality in the GM-CSF group (59.1%) compared to the non-GM-CSF group (35.1%, P = 0.001). …”
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1338
Brain atrophy in heart failure patients following left ventricular assist device implantation or heart transplantation
Published 2025-02-01“…Temporal atrophy (expansion of the Sylvian fissure) was greater in LVAD patients (median: 0.91 mm/year; IQR: 0.14–2.27) than HT patients (median: 0.10 mm/year; IQR: 0.02–0.55), p=0.005. …”
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1339
Experimental and Computational Analysis of Surgical Mask Effectiveness Against COVID-19 in Indoor Environment
Published 2023-08-01“…Abstract An experiment coupled with a computational analysis was conducted to investigate the effectiveness of surgical masks, which include KF94 and ASTM Level 1, in an indoor environment. The KF94 mask sample shows the highest filtration efficiency (99.9%) in the analysis. …”
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1340
Chemical characterization of Siraitia grosvenorii granules and their efficacy and mechanism of action on PM2.5-induced acute lung injury
Published 2025-01-01“…The specific targets and pathways through which the compounds exert their effects on acute lung injury were then predicted via network pharmacology. The lung-protective effects of SGG against particulate matter (PM2.5) were investigated via in vivo experiments. …”
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