A prognostic signature of Glutathione metabolism-associated long non-coding RNAs for lung adenocarcinoma with immune microenvironment insights by Junxi Hu, Junxi Hu, Shuyu Tian, Shuyu Tian, Qingwen Liu, Qingwen Liu, Jiaqi Hou, Jiaqi Hou, Jun wu, Jun wu, Xiaolin Wang, Xiaolin Wang, Yusheng Shu, Yusheng Shu

“…Quantitative PCR and experimental studies confirmed the role of lnc-AL162632.3 in LUAD.ResultsOur model included a total of nine lncRNAs, namely AL162632.3, AL360270.1, LINC00707, DEPDC1-AS1, GSEC, LINC01711, AL078590.2, AC026355.2, and AL096701.4. …”
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COPD with Eosinophilic Inflammation is Susceptible to Particulate Air Pollution Exposure by Amja Manullang, Chi-Li Chung, Yueh-Lun Lee, Tzu-Hsuen Yuan, Huan Minh Tran, Firdian Makrufardi, Kian Fan Chung, Kang-Yun Lee, Jer-Hwa Chang, Hsiao-Chi Chuang

“…An increase of 1 µg m−3 in PM2.5 was associated with a 0.38% (95% CI: −0.71%, −0.05%) decrease in the FVC. …”
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E-Cigarette Use and Use of Evidence-Based Smoking Cessation Methods Among American Indian Cigarette Smokers: A Cross-Sectional Analysis by Ashley L. Comiford, DrPH, Dorothy A. Rhoades, MD, MPH, Justin D. Dvorak, PhD, Kai Ding, PhD, Noah Collins, Alexandra L. Blair, Mark P. Doescher, MD, MSPH

“…Individuals with current or former use of E-cigarettes were significantly less likely than individuals who never used E-cigarettes to use the cold turkey method (unassisted cessation) (current versus never AOR=0.3, 95% CI=0.2, 0.6; past versus never AOR=0.3, 95% CI=0.1, 0.7; p<0.01). …”
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Comprehensive evaluation of the nutritional value and contaminants of alfalfa (Medicago sativa L.) in China by Xiaoyan Zhu, Xiaoyan Zhu, Xiaoyan Zhu, Wenxue Chen, Mengyao Li, Boshuai Liu, Boshuai Liu, Boshuai Liu, Shumin Zhao, Menglin Hu, Jiajing Li, Defeng Li, Defeng Li, Defeng Li, Yinghua Shi, Yinghua Shi, Yinghua Shi, Hao Sun, Hao Sun, Hao Sun, Chengzhang Wang, Chengzhang Wang, Chengzhang Wang

“…Nutritional value analysis and contamination evaluation are essential for sustainable utilisation to ensure the quality and safety of alfalfa.AimWe aimed to evaluate the nutritional value and safety of alfalfa in five major regions in China—the Northeast Plain (NP), Inner Mongolia Plateau (IMP), Northwest Desert Oasis (NO), Loess Plateau (LP), and Huanghuaihai Plain (HP).MethodsNinety-five samples representing 44 large-scale pratacultural companies were collected and analysed.ResultsThe average nutritional values of alfalfa hay were 16.43% crude protein (CP), 44.01% neutral detergent fibre (NDF), 33.22% acid detergent fibre (ADF), 10.78% crude ash (Ash), and 91.90% dry matter (DM), which were better in the NO and IMP areas; in particular, the α-linolenic acid value of alfalfa was the highest in the IMP area (p &lt; 0.05). …”
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Epidemiology of pelvic and acetabular fractures in a tertiary hospital in Singapore by Amritpal Singh, Amaris Shu Min Lim, Bernard Puang Huh Lau, Gavin O’Neill

“…The demographics of PAFs have changed, with fewer injuries in females (20.7% vs. 33.3%), a reduction in the proportion of injuries in the Chinese (51.5% vs. 70.1%). …”
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Non-lethal sonodynamic therapy mitigates hypertensive renal fibrosis through the PI3K/AKT/mTORC1-autophagy pathway by DanDan Liu, Hui Wang, Jialong Li, Siqi Sheng, Shu Wang, Ye Tian

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Epidemiologic trends and characteristics of cancer-related emergency department visits of older patients living with cancer in South Korea by Jung-In Ko, Sun Young Lee, Shin Hye Yoo, Kyae Hyung Kim, Belong Cho

“…The proportion of older adults among cancer-related ED visits increased from 50.1% in 2016 to 55.3% in 2020. The proportion of the “oldest old” (≥ 85 years) increased from 9.6 to 12.1%. …”
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CD22 modulation alleviates amyloid β-induced neuroinflammation by Yu Dong Mai, Qingqing Zhang, Cheuk Lim Fung, Shui On Leung, Chi Ho Chong

“…Here we reported that sCD22 promotes neuroinflammation both in vivo and in vitro. sCD22 activated microglia via both p38 and ERK1/2 signaling pathway for the secretion of TNFα, IL-6 and CCL3. …”
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Can Variation in Costs for Cardiovascular Procedures Be Attributed to Inefficiency in Care Delivery? Challenges in Causality, Data Availability, and the Need for Price Transparency by Waseem Nosair, MD, MPH, Morgana Mongraw-Chaffin, PhD, MPH, William S. Weintraub, MD

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Structural bioinformatics for rational drug design by Soroush Mozaffari, Agnethe Moen, Che Yee Ng, Gerry A.F. Nicolaes, Kanin Wichapong

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Patterns of orthodontic treatment of children in Australia: a national population-based study by Nguyen Philip Phu-Tan, Meade Maurice J., Jamieson Lisa M., Haag Dandara G.

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Beneath the surface: unveiling the gut–brain axis in anorexia and depression by Fatima Shahid, Zain Afridi, Muhammad Ali, Muhammad Nabeel Saddique, Javed Iqbal, Anurag Jha

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Effects of balanced opioid-free anesthesia on post-operative nausea and vomiting in patients undergoing video-assisted thoracic surgery: a randomized trial by Xiang Yan, Chen Liang, Jia Jiang, Ying Ji, An-Shi Wu, Chang-Wei Wei

“…The primary outcome was the incidence of PONV, which was assessed with the Myles’s simplified PONV impact scale during the initial 24 h after surgery. Results Compared with OBA group, the overall incidence of PONV in OFA group was significant reduced (14.6% vs. 30.1%, P = 0.017), and OFA reduced the risk of PONV events within 24 h of surgery (HR, 0.44; 95%CI: 0.22–0.87, P = 0.018). …”
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Disulfidptosis-related immune patterns predict prognosis and characterize the tumor microenvironment in oral squamous cell carcinoma by Xuechen Wu, Boxin Liu, Shi-Zhou Deng, Tengteng Xiong, Lin Dai, Bo Cheng

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Emerging insights into intravital imaging, unraveling its role in cancer immunotherapy by Minfeng Yang, Shiqiang Hou, Yao Chen, Hongzhao Chen, Minjie Chu, Song-Bai Liu

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Silica Nanoparticles Loaded With Selenium Quantum Dots Reduce Myocardial Ischemia-Reperfusion Injury by Alleviating Ferroptosis and Mitochondrial Dysfunction by Li T, Yang B, Liu X, Shi D, Wang Z, Chen Y, Shen C

“…Taixi Li,1,&ast; Boshen Yang,1,&ast; Xijian Liu,2 Dongmei Shi,1 Zhixiang Wang,1 Yizhi Chen,1 Chengxing Shen1 1Department of Cardiology, Shanghai Sixth People’s Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, 200233, People’s Republic of China; 2School of Chemistry and Chemical Engineering, Shanghai Frontiers Science Research Center for Druggability of Cardiovascular Noncoding RNA, Shanghai Engineering Technology Research Center for Pharmaceutical Intelligent Equipment, Shanghai University of Engineering Science, Shanghai, 201620, People’s Republic of China&ast;These authors contributed equally to this workCorrespondence: Chengxing Shen, Department of Cardiology, Shanghai Sixth People’s Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, 200233, People’s Republic of China, Email shencx@sjtu.edu.cnPurpose: Myocardial ischemia-reperfusion (IR) injury, a significant challenge in cardiovascular treatment, is primarily driven by ferroptosis and mitochondrial dysfunction. …”
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Potential of Adding Constructed Wetland/Fishpond to Waste Stabilization Ponds to Improve Helminths Removal in Morogoro Municipality, Tanzania by A.H. Outwater, A. Zachariah, A. Nyomora, F. Francis, J.H.Y. Katima

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Study some two loop contribution to muon anomalous MDM in the N-B-LSSM by Xing-Yu Han, Shu-Min Zhao, Long Ruan, Xi Wang, Xing-Xing Dong

“…Combined with the Fermilab National Accelerator Laboratory (FNAL) and the Brookhaven National Laboratory (BNL) E821 result, the departure from the SM prediction is about 5.0 $$\sigma .$$ σ . …”
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Lean Slipped Capital Femoral Epiphysis Draping by Laura Lins, MD, MPH, Laura L. Bellaire, MD, T. Peter Li, MD, PhD

“…This paper aims to describe the specific technique utilized at our institution to decrease the waste of draping materials and time to provide the most efficient procedure, while potentially minimizing radiation exposure. Key Concepts: (1) Providers and institutions should aim to decrease unnecessary surgical waste and improve surgical efficiency. (2) We describe a fast draping technique that decreases waste and can be used for stable or unstable SCFE on a radiolucent flattop or fracture table. (3) The draping technique on a radiolucent table can easily be adapted for bilateral procedures.…”
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Impact of copper stress in the intestinal barriers and gut microbiota of Chinese stripe-necked turtle (Mauremys sinensis) by Zeeshan Ali, Ijaz Khan, Muhammad Shahid Iqbal, Haitao Shi, Li Ding, Meiling Hong

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