Astaxanthin-loaded brain-permeable liposomes for Parkinson’s disease treatment via antioxidant and anti-inflammatory responses by Thai-Duong Nguyen, Shristi Khanal, Eunhee Lee, Jinsol Choi, Ganesh Bohara, Nikesh Rimal, Dong-Young Choi, Soyeun Park

“…We successfully formulated Lf-ASX-LPs with high encapsulation efficiency (97.6%) and favorable physical characteristics (diameter: 109.8 ± 1.1 nm; polydispersity index: 0.18 ± 0.01; zeta potential: − 9.5 ± 1.1 mV). …”
Get full text

Survival and risk factors for metastatic colorectal cancer patients with a history of prior malignancy by Yiwen Qiu, Nida Cao, Dan Meng, Jian Yuan, Yingjie Zhu

“…A history of prior malignancy was associated with a greater cancer-specific survival rate (adjusted hazard ratio (AHR) ) = 0.49; 95% CI [0.47–0.51]). Subgroup analyses revealed that a prior diagnosis of a skin tumour (AHR = 1.37; 95% CI [1.11–1.69]) and a history of prior malignancy of more than five years (AHR = 1.39; 95% CI [1.23–1.57]) had adverse effects on the clinical outcomes of patients with mCRC. …”
Get full text

Detection of Masses in Mammogram Images Based on the Enhanced RetinaNet Network With INbreast Dataset by Wang M, Liu R, Luttrell IV J, Zhang C, Xie J

“…Mingzhao Wang,1 Ran Liu,1 Joseph Luttrell IV,2 Chaoyang Zhang,2 Juanying Xie1 1School of Computer Science, Shaanxi Normal University, Xian, People’s Republic of China; 2School of Computing Sciences and Computer Engineering, University of Southern Mississippi, Hattiesburg, MS, USACorrespondence: Juanying Xie, School of Computer Science, Shaanxi Normal University, No. 620, West Chang’an Avenue, Chang’an District, Xi’an, 710119, Shaanxi, People’s Republic of China, Tel +86 13088965815, Email xiejuany@snnu.edu.cn Chaoyang Zhang, School of Computing Sciences and Computer Engineering, University of Southern Mississippi, 118 College Drive, Hattiesburg, MS, 39406-0001, USA, Email chaoyang.zhang@usm.eduPurpose: Breast cancer is the most common major public health problems of women in the world. …”
Get full text

Medicamentos intercambiáveis: impacto dos gastos sob a perspectiva de clientes de uma startup mineira by Cícero Quintão Celestino, Samilla Dornellas Faria, Ronaldo Portela, Isabella Piassi Dias Godói, Cristina Mariano Ruas

“…Resultados: A análise dos dados mostrou que os custos mensais dos tratamentos prescritos variaram de R$131,00 e R$1.219,66, enquanto os custos dos medicamentos potencialmente intercambiáveis variaram de R$98,00 a R$903,78. …”
Get full text

Lactate/albumin ratio as a prognostic biomarker for in-hospital mortality in pediatric patients with necrotizing enterocolitis by Ban Li, Yuanzhi Chen, Zhen Yang, Xianglun Sun, Cheng Tian, Jingsi Liu, Lihua Yuan, Kanglin Dai

“…The L/A ratio was a substantial predictor of in-hospital mortality, with an odds ratio (OR) of 5.24 (95% CI: 1.51–18.20, p = 0.01). An L/A cutoff value of 0.56 demonstrated a sensitivity of 0.923 and specificity of 0.486, with an AUC of 0.725 from the ROC curve analysis. …”
Get full text

Association of race and ethnicity with mortality in adults with SLE: a systematic literature review and meta-analysis by Sam Norton, Chris Wincup, Patrick Gordon, Kate Bramham, James Galloway, Zijing Yang, Samir Patel, Maryam Adas, Deepak Nagra, Mark Russell

“…Mortality was higher in Black patients (OR 1.30 (95% CI 1.16 to 1.46)) and Indigenous patients (OR 1.47 (95% CI 1.11 to 1.94)), while Asian and Hispanic patients showed no significant differences compared with White patients with SLE. …”
Get full text

Trust in the integrity of a micro health insurance scheme and its determinants in two rural districts of Ethiopia by Mohammed Hussien

“…In the multivariable regression analysis, age (AOR = 1.58; 95% CI: 1.10, 2.29), female gender (AOR = 2.05; 95% CI: 1.29, 3.25), education (AOR = 1.36; 95% CI: 1.03, 1.80), insurance membership status (AOR = 2.68; 95% CI: 1.89, 3.80), membership duration (AOR = 1.51; 95% CI: 1.19, 1.92), value for solidarity (AOR = 1.71; 95% CI: 1.20, 2.45), perceived risk protection (AOR = 3.35; 95% CI: 2.27, 4.96), and perceived quality of care (AOR = 1.78; 95% CI: 1.34, 2.37) were positive predictors of trust in the integrity of the scheme, while wealth index (AOR = 0.33; 95% CI: 0.23, 0.47), and hospitalization history (AOR = 0.62; 95% CI: 0.48, 0.82) were negative predictors of trust. …”
Get full text

Valores hematológicos del mono choro común (Lagothrix lagotricha) mantenido en cautiverio en la ciudad de Lima (Perú) by K. Cuestas, N. Carlos

“…Se obtuvieron los siguientes resultados: eritrocitos 8,76 x 106/μl (± 2,91); hematocrito 36,46% (± 3,38); hemoglobina 12,32 g/dl (± 1,89); VCM 60,61 fl (± 7,85); HCM 20,37 pg (± 3.07); CMCH 33,85 g/dl (± 4,61); leucocitos 6,12 x 103/μl (± 1,05); abastonados 0,05 x 103/μl (± 0,11); segmentados 5,54 x 103/μl (± 2,23); linfocitos 2,62 x 103/ul (± 1,60); monocitos 0,07 x 103/μl (± 0,02); eosinófilos 0,42 x 103/μl (± 0,23); basófilos 0,13 x 103/μl (± 0,14) y plaquetas 314,39 x 103/μl (± 78,09). …”
Get full text

The Single Leg Squat Test: A “Top-Down” or “Bottom-Up” Functional Performance Test? by Lindsay A Carroll, Benjamin R Kivlan, RobRoy L Martin, Amy L Phelps, Christopher R Carcia

“… # Methods Sixty-five healthy, active volunteers (sex = 50 female, 15 male; age = 25.2 +/- 5.6 years; height = 1.7 +/- .1 m; weight = 68.5 +/- 13.5 kg) who demonstrated static balance and hip abductor strength sufficient for performance of the SLST participated in the study. …”
Get full text

Indications, contributing factors, and short-term outcomes of pneumonectomy: an 8-year retrospective study in a resource-limited setting by Mekonnen Feyissa Senbu, Dereje Gulilat, Hiwot Tadesse Habtamu

“…Factors significantly associated with pneumonectomy included a history of tuberculosis treatment (AOR 40.3; 95% CI: 3.01, 540.2), intraoperative blood loss > 500 mL (AOR 9.07; 95% CI: 1.04, 79.13), and surgical duration > 180 min (AOR 37.9; 95% CI: 1.82, 792.3). …”
Get full text

Integrating Sports Massage into Pre-training Routines Can Enhance Athletic Preparedness and Performance Capacity in Kabaddi Players by Muhammad Isnandar, Farid M. Alhumary, Krzykarist Krzykarist, Restin Zega, Reymond Benedith Hutajulu, Rachel Junika Abelia Putri, Martin Hofmeister

“…All observed improvements were statistically significant (p < 0.001) and characterized by large effect sizes. …”
Get full text

Quinoid to benzenoid transition-driven glutathione sensing: Dual-emission carbon dots and smartphone-based ratiometric fluorescence analysis by Al-Montaser Bellah H. Ali, Ashraf M. Mahmoud, Yousef A. Bin Jardan, Aya M. Mostafa, James Barker, Mohamed M. El-Wekil

“…This study presents a novel and sensitive method for the determination of glutathione (GSH), a crucial antioxidant and cellular protectant, using dual blue/orange-emitting carbon dots (BOCDs) and phenolphthalein (PHP). The sensing system operates at pH 9.0, exploiting the unique optical properties of BOCDs with emission peaks at 420 nm and 570 nm. …”
Get full text

Digital sleep phenotype and wrist actigraphy in individuals at clinical high risk for psychosis and people with schizophrenia spectrum disorders: a systematic review and meta-analy... by Andrea Cipriani, Edoardo Giuseppe Ostinelli, John Torous, Paolo Brambilla, Philip McGuire, Dominic Oliver, Rosario Aronica, Charlotte Austin

“…Factors such as antipsychotic medications (pseudo-R²=88.14%), age (38.89%) and gender (26.29%) partially explained the heterogeneity between subgroups. Additionally, CHR-P individuals exhibited reduced sleep efficiency (MD −2.04% (−3.55 to 0.53)), whereas SSD participants had increased TIB (MD 121.58 min (88.16 to 155.00)) and sleep latency (MD 13.05 min (2.11 to 24.00)). …”
Get full text

Implementación de la técnica del hexafluoruro de azufre para cuantificar metano entérico en bovinos en Costa Rica by Johnny Montenegro Ballestero, Eduardo Barrantes Guevara

“…La emisión diaria de metano por novilla en estabulación fue 147±7 g, y de 17,3±1,1 g kg-1 de masa seca (MS) consumida. En pastoreo se emitieron 141±16 g de CH4, y se estiman 16,1±1,1 g de CH4 kg-1 MS de pasto consumido. …”
Get full text

Low Fifth-Minute Apgar Score Analysed According to Robson Ten Group Classification at a Tertiary Hospital in Nigeria by Olakunle Makinde, Benjamin O. Awotundun, Nkencho Osegi

“…Neonates of parturients in Robson groups 6a (OR - 11.00; 95% CI-1.27-95.18; p Value-0.029), 7a (OR-17.29; 95% CI-3.06-97.52; p value-0.001), 9a (OR-11.00; 95% CI-1.48-81.61; p Value-0.019), 10a (OR-12.69; 95% CI-2.49 - 64.58; p value-0.002) and 10b (OR-22.00; 95% CI-1.33 -362.92; p value-0.031) had significantly higher odds of low fifth-minute APGAR score relative to 8c with the lowest group rate. …”
Get full text

Elevated POSTN expression predicts poor prognosis and is associated with radioresistance in cervical cancer patients treated with radical radiotherapy by Cui-qin Huang, Wen-tao Xiao, Xiang-rong Yao, Zhi-min Li, Jun-yan He

“…Subsequently, in vitro experiments confirmed that POSTN knockdown significantly inhibited HeLa cell proliferation, invasion, and enhanced radiosensitivity, while promoting apoptosis. …”
Get full text

Breeding for Heat Tolerant Aromatic Rice Varieties and Identification of Novel QTL Regions Associated with Heat Tolerance During Reproductive Phase by QTL-Seq by Surangkana Chimthai, Sulaiman Cheabu, Wanchana Aesomnuk, Siriphat Ruengphayak, Siwaret Arikit, Apichart Vanavichit, Chanate Malumpong

“…Regarding the QTL-seq results, the qSF2.1 region ranged from 311 051 to 3 929 422 bp on chromosome 2, was identified based on the highest contrasting SNP index between the heat-susceptible and tolerant bulks. …”
Get full text

Health Risk Assessment of PM2.5-bound Components in Beijing, China during 2013–2015 by Tianchu Zhang, Yangfan Chen, Xiaohong Xu

“…HQ by PM2.5-bound elements were, in descending order, Cl (14), As (1.8), Pb (0.94), P (0.81), Cd (0.22), Mn (0.22), Ni (0.18), Ba (0.1), Cr(VI) (0.03), Co (0.01), and Se (0.002). …”
Get full text