Costs of Potential Medication Wastage Due to Switching Treatment Among People With Multiple Sclerosis by Darin T. Okuda, Achal Patel, Robert Schuldt, Ibraheem Abioye, Nicole G. Bonine

“…Approximately 95% of PwMS switched DMTs once within single calendar years, and 25% (n = 381-464) contributed to PMW. For those who had overlapping DMT supply, it was estimated that 34% to 38% of the DMT being switched from was potentially wasted. …”
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Treatment Patterns and Outcomes Among Patients With Advanced or Recurrent Endometrial Cancer Initiating First-Line Therapy in the United States by Robert L. Coleman, Jamie Garside, Jean Hurteau, Joehl Nguyen, Monica Kobayashi

“…Of the patients who received at least 1 LOT, use of immunotherapy in the second-line setting was more common in the dMMR/MSI-H subgroup. …”
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The impact of a 5G-based smart nursing information system and associated mobile hardware on clinical nurses’ work stress: a randomized controlled study in a Chinese hospital by Xuejiao Ruan, Yuying Lou, Xinhua Zhang, Zhulin Wu, Hongzhi Yuan

“…The SNIS-SMH group showed significantly lower total work stress scores (66.16 ± 9.82) compared to the control group (70.65 ± 11.32, P = 0.002). In specific dimensions, the SNIS-SMH group had lower scores for nursing profession and work (14.17 ± 2.37 vs. 15.00 ± 3.06, P = 0.023), workload and time distribution (10.56 ± 2.45 vs. 12.42 ± 2.55, P < 0.001), and patient care (22.55 ± 3.34 vs. 23.70 ± 4.06, P = 0.021). …”
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Dynamic Functional Ability in Lacrosse Players in Relation to Development of Sport-Related Onset of Musculoskeletal Pain by Zane Thompson, Joseph G. Wasser, Kevin R. Vincent, Heather K. Vincent

“…Single leg squat performance score increased the odds risk (OR) for lower extremity pain (OR=2.62 \[95% CI 1.06-6.48], p=.038) and LESS scores elevated risk for low back pain onset over six months (OR = 2.09 \[95% CI 1.07- 4.06], p= .031)…”
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Annual Zoledronic Acid for the Treatment of Osteoporosis: A Randomized Controlled Trial by Asif Hussain, Sushil Kumar Saini, Jaydeep Patel, Chandra Prakash Pal, Hemant Singh Chahar, Rohit Yadav

“…Results: The primary outcome was reduced by 79% during the 1-year period in zoledronic acid, compared to placebo (3% in the treatment group vs. 14% in the placebo group; relative risk (RR): 0.21; 95% confidence interval [CI]: 0.06–0.72, P = 0.01). …”
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An Interval Throwing Program for Baseball Pitchers Based upon Workload Data by Michael M. Reinold, Brittany Dowling, Glenn S. Fleisig, Leonard C. Macrina, Kevin E. Wilk, John T. Streepy, James R. Andrews

“… # Results The original ITP had a throwing schedule of 136 days, final chronic workload 15.0, and the ACWR above or below the "safe" range (i.e. 0.7 -- 1.3) for 18% of the program with a peak of 1.61. …”
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Spatial-temporal Pattern of the “Grain-for-Green Project” and Its Carbon Sequestration Effect in Guizhou Province by TAI Liang, CHEN Jia, LONG Wentao, CAI Huayin, WANG Xinxing

“…[Methods] Taking Guizhou Province as an example, the spatial and temporal distribution pattern and carbon stock changes of the “Grain-for-Green Project” in Guizhou Province from 2000 to 2020 were investigated by using ArcGIS in combination with the InVEST model. [Results] (1) During the 20-year period, land use in Guizhou Province had changed significantly, and the comprehensive dynamic had shown a downward and then an upward trend, which was 0.32%, 0.11%, 0.09%, 0.35% in order. …”
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Why PD-L1 expression varies between studies of lung cancer: results from a Bayesian meta-analysis by Preston Ngo, Wendy A. Cooper, Stephen Wade, Kwun M. Fong, Karen Canfell, Deme Karikios, Marianne Weber

Subjects: “…PD-L1…”
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Experience of Acceptance and Commitment Therapy for those with mild traumatic brain injury (ACTion mTBI): A qualitative descriptive study. by Josh W Faulkner, Jason Chua, Amabelle Voice-Powell, Deborah L Snell, Maree Roche, John Moffat, Suzanne Barker-Collo, Alice Theadom

“…We recruited adults (≥16 years of age) diagnosed with mTBI who were engaged in community-based multidisciplinary rehabilitation. …”
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Efficacy and Safety of Bicyclol Treatment for Non-Alcoholic Fatty Liver Disease: Results of a Cohort Study by I. Yu. Pirogova, S. V. Yakovleva, T. V. Neuymina, S. P. Sinitsyn, V. S. Chulkov, T. N. Shamaeva

“…During Bicyclol treatment, a decrease in the following indicators was observed: ALT, AST, GGT, CRP by 30 % or more, glycated hemoglobin (–10 %) and HOMA-index (–24 %), cholesterol (–12 %), LDL (–19 %), triglycerides (–31 %), atherogenic coefficient (–22 %). A decrease to the1st stage of fibrosis was observed in 30 patients (44 %), steatosis regression to the 1st stage was noted in 57 patients (85 %). …”
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A decade-long overview of adverse events in a tertiary surgical service in South Africa by H Wain, D L Clarke, S Wall

“…Pathology-related adverse events contributed 21.4% of the total, of which wound sepsis (29.5%), anastomotic leak (15.1%) and nosocomial pneumonia (14.4%) were the most common. …”
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Association between common mental disorder and glycemic control in women with gestational diabetes: A mixed-method study by Bhanushree Soni, Venkatachalam Jayaseelan, Shivanand Kattimani, Sasirekha Rengaraj, Kalaiselvy Arikrishnan, Naveenkumar Veerasetty

“…Results: The prevalence of CMD was found to be 19.08% (95% CI: 15.32%-23.52%), with 18.2% (95% CI: 14.5%-22.6%) anxiety symptoms 8.3% (95% CI: 5.8%-11.6%) depressive symptoms and stress each. CMD was significantly related to poor glycemic control (aPR: 1.58; 95% CI: 1.23-2.03; P value <0.001). …”
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Exploring the influence of light conditions on the antifungal, antioxidant, and cytotoxic potential of N. persica A1387 by Bahareh Nowruzi, Radin Norouzi, Romina Norouzi

“…In contrast, blue light had the most pronounced effect on antioxidant activity, increasing it by 1.01–1.02 times compared to red light and 1.21–1.22 times compared to white light, as measured by the ABTS method. …”
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Self-Assessment of Medical Ethics and Professionalism: Comparison Between Preclinical and Clinical Medical Students by Saima Naz Shaikh, Uzair Abbas, Tazeen Shah, Arsalan Ahmad Uqaili, Hudebia Allah Buksh, Mehreen Fatima

“…Moreover, among the components of professionalism, there was a significantly higher score for confidentiality ( P  = .006), communication skills ( P  = .001), self-directed learning ( P  = .011), peer and self-assessment ( P  = .0011) along with ethics in research and patient care ( P  = .0042) in clinical students as compared to preclinical medical students. …”
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The Unignorable Near-ground PM2.5, UFP, PAHs, and BC Levels around a Traffic Prohibited Night Market by Sheng-Lun Lin, Hongjie Zhang, Ming-Yeng Lin, Shih-Wei Huang

“…Through traffic restriction, it was found that all kinds of pollutants increased significantly before restriction, and even after restriction, the concentrations of PM2.5 and BC increased 131% and 151% in low concentration season. In the high concentration season, the traffic restriction significantly reduced the NG-UFP and NG-PAH concentration by 27% and 55%, respectively, but NG-BC and NG-PM2.5 was almost unaffected. …”
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The Incidence of Nosocomial Bloodstream Infections in Children With Congenital Heart Disease Undergoing Cardiac Surgery: A Retrospective Study by Mohammad Mehdi Rajabi, Behdad Gharib, Mohammad Reza Mirzaaghayan

“…The results showed that the incidence of BSIs in pediatric CHD patients after cardiac surgery was 3.21%. Postoperative blood cultures revealed that Klebsiella pneumoniae was the most common pathogen (42.9%), followed by Escherichia coli and Staphylococcus epidermidis (14.3% each). …”
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Preparation For Flight: The Physical Profile of Pre-Professional and Professional Circus Artists in the United States by Stephanie J Greenspan, Melanie I Stuckey

“… # Study Design Descriptive laboratory study # Methods Circus artists (n=201; ages 13-69y; 172 females ASAB, 29 males ASAB) from 10 cities across the United States underwent a baseline physical examination including shoulder, hip and trunk measures of passive (PROM) and active (AROM) range of motion, measures of flexibility (shoulder and hip), strength (manual muscle tests, grip strength), cardiovascular fitness (3 minute-step test), balance (single limb and handstand), and performance, (pull-ups, and the closed kinetic chain upper extremity stability test \[CKCUEST\]). …”
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Variation in the quality of charcoal from Acacia decurrens (J.C. Wendl.) Willd. with age and longitudinal stem portions by Minichil Mengistu, Yashwant S. Rawat, Anteneh T. Tekleyohannes, Sisay F. Asfaw

“…The results showed a significant age-based variation in moisture content with magnitude ranging from 6.10% to 10.48%, in volatile matter from 20.05% to 26.33%, in ash content from 2.97% to 7.30%, in fixed carbon from 56.29% to 70.51%, in total carbon 82.61% to 90.56% and in basic wood density from 0.71 g‧cm-3 to 0.91 g‧cm-3. …”
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Organizational Support and Employee Commitment in Public Sector: A Case Study of Kabale District Local Government, Uganda. by Nassali, Joan

“…The majority of participants in the study (67.1%) felt secure in their employment at the end. …”
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An examination of the correlation between website traffi c and the quality of services provided by Jumia Uganda. by Ssemaluulu, Paul Mukasa, Isingoma, Fenehansi, Mugavu, George

“…The significance level for both correlations was 0.000, indicating that the correlation coefficients were highly significant at the 0.01 level (2-tailed). This positive correlation implies a connection between website traffic and service quality. …”
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