Risk Factors of Portal Vein Thrombosis in Patients with Different Child-Pugh Classes Liver Cirrhosis by M. Yu. Nadinskaia, Kh. B. Kodzoeva, K. A. Gulyaeva, M.-D. E. Khen, D. I. Koroleva, M. A. Privalov, A. Kh. Tekaeva, V. R. Fedorov, S. G. Prokofev

“…The cutoff by the portal vein diameter was the same for both classes — 13.4 mm; the spleen length was similar and amounted 17.5 mm for class A, 17.1 mm for class B/C. Patients with PVT differed from the corresponding controls by neutrophil-to-lymphocyte ratio: class A 2.33 (1.82; 3.61) vs. 1.76 (1.37; 2.20), p < 0.01, class B/C 2.49 (1.93; 3.34) vs. 2.15 (1.49; 3.26), p < 0.05. …”
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Association between triglyceride-glucose index and clinical outcomes among patients with chronic kidney disease: a meta-analysis by Jinli Tuo, Zhong Li, Linshen Xie

“…Pooled results indicated that elevated TyG index was significantly related to increased risk for all-cause mortality (HR = 1.22, 95% CI: 1.13–1.31, P<0.001). Besides, high TyG index was also associated with the CAD mortality (HR = 1.19, 95% CI: 1.04–1.36, P = 0.011), occurrence of CKD progression (HR = 1.52, 95% CI: 1.36–1.70, P<0.001), SCAS (OR = 1.79, 95% CI: 1.13–2.83, P = 0.013), MACE (OR = 1.68, 95% CI: 1.11–2.54, P = 0.014), CAC progression (OR = 1.55, 95% CI: 1.06–1.76, P = 0.02), CAD (OR = 2.865, 95% CI: 1.681–4.885, P<0.001), ESRD (OR = 1.49, 95% CI: 1.12–1.99, P = 0.006) and NAFLD (OR = 4.903, 95% CI: 3.046–7.893, P<0.001). …”
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Genetic analysis of pathways regulated by the von Hippel-Lindau tumor suppressor in Caenorhabditis elegans. by Tammie Bishop, Kah Weng Lau, Andrew C R Epstein, Stuart K Kim, Min Jiang, Delia O'Rourke, Christopher W Pugh, Jonathan M Gleadle, Martin S Taylor, Jonathan Hodgkin, Peter J Ratcliffe

“…We show tight conservation of the HIF-1/VHL-1/EGL-9 hydroxylase pathway. However, persisting differential gene expression in hif-1 versus hif-1; vhl-1 double mutant worms clearly distinguished HIF-1-independent effects of VHL-1 inactivation. …”
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Range of Motion and Muscle Stiffness Differences in Junior Tennis Players with and without a History of Shoulder Pain by Joshua Colomar, Javier Peña, Jordi Vicens-Bordas, Ernest Baiget

“… # Results There were significant differences between the shoulder pain and no shoulder pain group in the D IR (-3.1º, 6.43%, p = 0.048; effect size \[ES\] = 0.58) and D TAM (-6.1º, 3.01%, p = 0.024; ES = 0.66). …”
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The Effects of Pre-Pregnancy Body Mass Index and Weight Gain During Pregnancy on Perinatal Outcomes: A Retrospective Cohort Study by Engin Yurtcu, Sibel Mutlu, Enis Ozkaya

“…RESULTS: According to pre-pregnancy body mass index, among the obese pregnant group, gestational diabetes mellitus (p<0.001), preeclampsia (p=0.029), preterm delivery (p=0.011) and cesarean delivery (p=0.061) rates were more common. …”
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Clinical outcomes of nephroureterectomy with bladder cuff excision or radical cystectomy for distal ureteral carcinoma invaded muscle of the ureteral orifice by Pan Li, Suoshi Jing, Yindong Kang, Bin Feng, Yunxin Zhang, Hui Ding, Juan Wang, Yingru Wang, Li Yang, Zhilong Dong, Junqiang Tian, Zhiping Wang, Zizhen Hou

“…Apart from NU-RC (HR, 0.18; 95%CI: 0.08–0.44; p < 0.001) (HR, 0.28; 95%CI: 0.1–0.79; p = 0.016) and tumor volume(HR, 1.17; 95%CI: 1.06–1.29; p = 0.002) (HR, 1.21; 95%CI: 1.11–1.31; p < 0.001), which are independent prognostic factors for RFS and CSS, another independent prognostic factor for CSS is the ureteral carcinoma with renal pelvic carcinoma (HR, 4.32; 95%CI: 1.28–14.511; p = 0.018). …”
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Comparison of live birth rate and fetal outcomes between fresh embryo and frozen-thawed embryo transfers: a prospective study by Seyedeh Farinaz Fattahpour, Parvin Hakimi, Fatemeh Tabatabaei, Mahsa Hejazad, Maryam Amoozadeh, Leila Sadeghi, Negin Rezaie, Razih Vejdani, Hosein Azizi

“…In the final analysis, after adjusting for potential confounders, no significant associations were found for clinical pregnancy (AOR = 1.51; 95% CI: 0.90–2.5; P = 0.125) and chemical pregnancy (AOR = 1.31; 95% CI: 0.81–2.3; P = 0.238) rates between fresh and frozen ETs. …”
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Clinical Burden and Healthcare Resource Use of Asthma in Children in the UK by Gouia I, Joulain F, Zhang Y, Morgan CL, Khan AH

“…All-cause HCRU (IRR [95% CI]) was higher in severe asthma patients versus controls (primary care: 3.81 [3.54– 4.09], P< 0.0001; inpatient admissions: 3.23 [2.31– 4.62], P< 0.0001]); total-cost ratios relative to controls for mild, moderate, and severe asthma were 1.58 (1.39– 1.78, P< 0.0001), 2.56 (1.97– 3.33, P< 0.0001), and 3.42 (2.54– 4.61, P< 0.0001), respectively. …”
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Comprehensive investigation of ergonomic challenges and predictors of work-related musculoskeletal disorders among intensive care unit nurses of Western India through convergent mi... by Sonali Detroja, Rajkumar Mahajan, Ankit Sheth

“…Nurses with WRMSDs reported significantly higher mean scores for physical factors (15.1 vs. 11.1, p = 0.00), physical workload (12.8 vs. 10.7, p = 0.001), work environment (13.1 vs. 10.1, p = 0.00), and risk perception (11.8 vs. 8.9, p = 0.00) compared to those without WRMSDs. …”
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Associations of heavy metals and urinary sodium excretion with obesity in adults: A cross-sectional study from Korean Health Examination and Nutritional Survey. by Juyeon Lee, Sue K Park

“…Associations between heavy metals (cadmium, mercury), urinary arsenic, sodium excretion levels, and overweight/obesity were assessed using polytomous logistic regression models, adjusting for confounders.<h4>Results</h4>Higher mercury (OR = 1.57, 95% CI = 1.31-1.88) and urinary sodium (OR = 2.21, 95% CI = 1.84-2.66) levels are associated with an increased risk of overweight and obesity. …”
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Hispanic Patients Undergoing Spinal Fusion for Neuromuscular Scoliosis Sustain Health Inequalities by Armando S. Martinez, David Momtaz, Travis Kotzur, Alexandra McLennan, Abdullah Ghali, Farhan Ahmad, Ebubechi Adindu, Alan C. Santiago-Rodriquez, Ali Seifi, Brian Smith

“…Results: Compared to non-Hispanic patients (N=1829), Hispanic patients (N=431) had spinal fusion with instrumentation at younger ages (12.9 vs. 14.1 years old, p=0.011) and had significantly different household incomes with less representation in the 75th to 100th percentile (16.8% vs. 26.5%, p<0.001). …”
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Users’ Perspectives of Direct-to-Consumer Telemedicine Services: Survey Study by Kate Churruca, Darran Foo, Andrew Turner, Emily Crameri, Maree Saba, Samantha Spanos, Matthew Vickers, Jeffrey Braithwaite, Louise A Ellis

“…ResultsAmong the 151 respondents, most (136/151, 90.1%) had seen a general practitioner (GP) in the previous 12 months and were somewhat or very satisfied (118/136, 86.8%) with the care, just over half found it easy to get an appointment with their GP (76/151, 50.3%), and a quarter found it difficult (38/151, 25.2%). …”
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Lenvatinib Therapy in Patients with Unresectable Hepatocellular Carcinoma in Real Clinical Practice by V. V. Petkau, A. V. Sultanbaev, K. V. Menshikov, A. S. Antipin, M. V. Volkonsky, V. M. Filippova, Yu. V. Vasilyeva, A. A. Tarkhanov, M. R. Mukhitova, M. Zh. Murzalina, A. R. Safarova

“…The median OS and PFS comprised 14.6 (95 % CI 10.6–18.6) and 11.1 months (95 % CI 8.31–13.8), respectively. The ORR amounted to 32.8 %, while DCR reached the level of 79.3 %. …”
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Determination of the physicochemical and microbiological quality of buffalo milk in the south of lake Maracaibo by Luis Álvarez, Alexis Zambrano, Datty Rosales-Zambrano

“…The average physicochemical values of the three raw milk samples from farms evaluated were for A, B, C and D respectively: Acidity: 17.1 ± 0.8**; 17.67 ± 0.5*; 16.8 ± 0.7*; 17.6 ± 0.5*; % Fat: 5.2 ± 0.4**; 6.5 ± 0.4**; 6.4 ± 0.5**; 6.6 ± 0.1**; Solid non-fat (SNG): 9.3 ± 0.1*; 9.7 ± 0.2*; 9.9 ± 0.2**; 9.7 ± 0.2*; Lactose: 5.1 ± 0.1*; 5.3 ± 0.1*; 5.4 ± 0.1**; 5.3 ± 0.1*; % Protein: 4.14 ± 0.03*; 4.21 ± 0.04*; 4.25 ± 0.04*; 4.27 ± 0.06*; and Cryoscopy: 0.61 ± 0.01*; 0.64 ± 0.01*; 0.66 ± 0.02**; 0.65 ± 0.02*: The averages of the samplings of the milk mixtures E (milk silo) and F (pasteurized milk) obtained: Acidity: 17.6 ± 0.5*; 18.3 ± 0.7*; % Fat: 6.0 ± 0.2**; 3.9 ± 0.6**; SNG: 9.7 ± 0.2**; 8.1 ± 0.6**; Lactose: 5.3 ± 0.1**; 4.4 ± 0.3**; % Protein: 4.16 ± 0.03*; 3.7 ± 0.3** and Cryoscopy: 0.64 ± 0.02**; 0.51 ± 0.04**. (**) Presents a significant difference between the results obtained during the three months of sampling (Tukey, p < 0.05). …”
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Matching-Adjusted Indirect Comparison of the Efficacy and Safety of Erdafitinib vs Enfortumab Vedotin in Patients with Locally Advanced Metastatic Urothelial Carcinoma by Suzy Van Sanden, Ayman Youssef, Simona Baculea, Keith Stubbs, Spyros Triantos, Zijiao Yuan, Caitlin Daly

“…For safety, MAIC-yielded risk ratios of 1.09 (0.99, 1.21) for any treatment-related adverse events, 0.86 (0.57, 1.28) for grade 3+ TRAEs, and 1.02 (0.98, 1.06) for any treatment-emergent adverse events. …”
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Muscle Activity and Kinematics During Three Hamstring Strengthening Exercises Compared to Sprinting: A Cross-Sectional Study. by Adelso Jorge, Eric Lichtenstein, Oliver Faude, Ralf Roth

“… # Results Eight male athletes were included (age: 24.0 years ± SD 2.9; body mass: 76.8 kg ± 7.7; height: 1.79 m ± 0.08). Greater activity of the hamstrings occurred during the explosive exercises ranging from 63.9% [95%CI: 56.3-71.5%] (rocker) to 49.0% [95%CI: 40.4-57.6%] (PMfast) vs. 34.0% [95%CI: 29.1-38.9%] (NHE) to 32.1% [95%CI: 26.9-37.3%] (PMslow). …”
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Femur Length is Correlated with Isometric Quadriceps Strength in Post-Operative Patients by Robert S Dean, Nicholas N DePhillipo, Michael T Kiely, Nicole A Schwery, Jill K Monson, Robert F LaPrade

“…At an average of 5.8±2.5 months postoperatively, the peak torque (156.6 vs. 225.1 Nm), average peak torque (151.6 vs. 216.7 Nm), and peak torque to bodyweight (2.01 vs 2.89 Nm/Kg) were significantly greater in the non-surgical limb (p<0.01). …”
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Reliability of the Expanded Cutting Alignment Scoring Tool (E-CAST) to Assess Trunk and Limb Alignment During a 45-Degree Side-Step Cut by Lauren S. Butler, Alexa R. Martinez, Dai Sugimoto, Charles W. Wyatt, Eryn K. Milian, Sophia Ulman, Ashley Erdman, Alex Loewen, Kristin Hayden, Amie DeVerna, Kirsten Tulchin-Francis, PRiSM Injury Prevention Research Interest Group

“… # Conclusion The addition of two sagittal plane variables resulted in lower inter-rater ICC compared to the CAST (ICC= 0.81, 95% CI 0.64-0.91). The E-CAST is a reliable tool to evaluate trunk and LE alignment during a 45-degree side-step cut, with good intra-rater and moderate inter-rater reliability…”
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Pre-existing atrial fibrillation and risk of arterial thromboembolism and death following pneumonia: a population-based cohort study by Reimar Wernich Thomsen, Christian Fynbo Christiansen, Bodil Steen Rasmussen, Lars Hvilsted Rasmussen, Jacob Gamst

“…Among patients with AF, reduced risk of ATE was observed in vitamin-K antagonist users compared with non-users (aHR 0.74 (95% CI 0.61 to 0.91)). Thirty-day mortality was 20.1% in patients with AF and 13.9% in patients without AF. …”
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SEX PREFERENCE IN MATERNAL HEALTH IN LOKOJA KOGI STATE by Silas Joshua, Nancy Yusuf

“…The result shows that the highest births occurred in the month of September with 11.4% births of 94 males and 81 females. This was followed by births in the months of July and May with 11.1% and 11.0% of the births respectively, reflecting 96 male and 74 female born in July and 101 male and 68 female delivered in May. …”
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