A Synoptic- and Remote Sensing-based Analysis of a Severe Dust Storm Event over Central Asia by Parya Broomandi, Kaveh Mohammadpour, Dimitris G. Kaskaoutis, Aram Fathian, Sabur F. Abdullaev, Vladimir A. Maslov, Amirhossein Nikfal, Ali Jahanbakhshi, Bakhyt Aubakirova, Jong Ryeol Kim, Alfrendo Satyanaga, Alireza Rashki, Nick Middleton

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Complex congenital heart and lung defects as a cause of hydrops fetalis in French bulldogs –micro-CT with contrast study by Olga Szaluś-Jordanow, Karolina Barszcz, Wojciech Mądry, Michał Buczyński, Michał Czopowicz, Adam Gierulski, Agata Moroz-Fik, Zofia Nowek, Marcin Mickiewicz, Michał Grzegorczyk, Jakub Jaroszewicz, Sylwia Tarka, Tomasz Stępień, Wojciech Święszkowski

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Development of a TCR-like antibody and chimeric antigen receptor against NY-ESO-1/HLA-A2 for cancer immunotherapy by Xin Liu, Yang Du, Ningyan Zhang, Zhiqiang An, Wei Xiong, Yixiang Xu, Bingnan Yin, Yuqian Huang, Junjun Chu, Changsheng Xing, Chen Qian, Tianhao Duan, Helen Y Wang, John S. Yu, Rongfu Wang

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Activity-based chemical proteomics reveals caffeic acid ameliorates pentylenetetrazol-induced seizures by covalently targeting aconitate decarboxylase 1 by Guanjun Li, Ling Huang, Di Gu, Peili Wang, Letai Yi, Wenhua Kuang, Ying Zhang, Junzhe Zhang, Dandan Liu, Qiaoli Shi, Huan Tang, Jichao Sun, Guohua Zeng, Xin Peng, Jigang Wang

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Diethyldithiocarbamate-copper complex ignites the tumor microenvironment through NKG2D-NKG2DL axis by Daciana C. Dumut, Daciana C. Dumut, Marian Hajduch, Marian Hajduch, Amanda M. Zacharias, Qingling Duan, Qingling Duan, Ivo Frydrych, Zuzana Rozankova, Zuzana Rozankova, Miroslav Popper, Miroslav Popper, Dusan Garic, Radu Alexandru Paun, Radu Alexandru Paun, Amanda Centorame, Amanda Centorame, Juhi Shah, Martin Mistrik, Martin Mistrik, Petr Dzubak, Petr Dzubak, Juan B. De Sanctis, Juan B. De Sanctis, Danuta Radzioch, Danuta Radzioch, Danuta Radzioch, Danuta Radzioch

“…This study unveils a novel mechanism of action for CuET: a potent immunomodulator capable of turning cold tumors hot.…”
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A deep learning approach for automatic 3D segmentation of hip cartilage and labrum from direct hip MR arthrography by Malin Kristin Meier, Ramon Andreas Helfenstein, Adam Boschung, Andreas Nanavati, Adrian Ruckli, Till D. Lerch, Nicolas Gerber, Bernd Jung, Onur Afacan, Moritz Tannast, Klaus A. Siebenrock, Simon D Steppacher, Florian Schmaranzer

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Outcome and Determining Characteristics of ICU Patients with Acute Kidney Injury in a Low-Income Country, a Multicenter Experience by Ballah Abubakar, Mohammed Jika, Njidda Gyadale Abdulhamid, Yahaya Halima Bidemi, Rosemary Nwokorie Mabong, Naziru Ibrahim, Baffah Adamu Yusuf, Maina Hassan Ali, Galadima Hajara, Mohammed Abdullahi Maryam, Andibanbang Franklin, Abdullahi Adam Ibrahim

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The biodiversity survey of the Cape (BioSCape), integrating remote sensing with biodiversity science by Anabelle W. Cardoso, Erin L. Hestir, Jasper A. Slingsby, Cherie J. Forbes, Glenn R. Moncrieff, Woody Turner, Andrew L. Skowno, Jacob Nesslage, Philip G. Brodrick, Keith D. Gaddis, Adam M. Wilson

“…Over six weeks, an international team of ~150 scientists collected data across terrestrial, marine, and freshwater ecosystems in South Africa. …”
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Coupling of an Au@AgPt nanozyme array with an micrococcal nuclease-specific responsiveness strategy for colorimetric/SERS sensing of Staphylococcus aureus in patients with sepsis by Xueqin Huang, Yingqi Yang, Hanlin Zhou, Liping Hu, Annan Yang, Hua Jin, Biying Zheng, Jiang Pi, Jun Xu, Pinghua Sun, Huai-Hong Cai, Xujing Liang, Bin Pan, Junxia Zheng, Haibo Zhou

“…Overall, benefiting from highly active and dense “hot spot” substrate, MNase-mediated cascade response strategy, and colorimetric/SERS dual-signal output, this methodology will offer a promising avenue for the early diagnosis of S. aureus infection.…”
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Transforming lemon Peel into a sustainable reservoir of bioactives: A green osmotic dehydration strategy by Priyanka Prajapati, Chhavi Porwal, Meenakshi Garg, Neha Singh, Susmita Dey Sadhu, Rajni Chopra, Eram S. Rao, Aparna Agarwal, Mohd Saeed, Safia Obaidur Rab, Dipendra Kumar Mahato, Pradeep Kumar, Madhu Kamle, Abhishek Dutt Tripathi

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Optimized framework for evaluating F3 transgressive segregants in cayenne pepper by Ifayanti Ridwan, Muh Farid, Feranita Haring, Nuniek Widiayani, Ahmad Yani, Nirwansyah Amier, Muhammad Alfan Ikhlasul Amal, Jekvy Hendra, Nawab Ali, Mekhled Mohamed Alenazi, Mahmoud F. Seleiman, Willy Bayuardi Suwarno, Muhammad Fuad Anshori

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Discovery of phloridzin as a new antagonist for Di(2-ethylhexyl) phthalate-induced male reproductive toxicity based on the adverse outcome pathway network and drug-target gene set... by Huan Gao, Xue Zhang, Ziqi Liu, Xiaoge Yang, Yajie Li, Mengxing Cui, Han Wang, Xiaoyu Chen, Weiying Zhang, Zhihan Liu, Yongjiang Yu, Liping Chen, Daochuan Li, Yongmei Xiao, Wen Chen, Qing Wang

“…After functional enrichment analyses and mapping to the global AOP network, we found that the increased ROS level, cell cycle arrest, and increased apoptosis are key events (KEs) involved in DEHP-mediated MRT, which was validated in TM3 Leydig cell model. Among them, cellular apoptosis is the core KE in DEHP-induced MRT via network topological analysis. …”
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Case study: Stomach ulcers in the context of tricuspid atresia—“I can barely stomach it” by Thomas C. Varkey, Chloe-Marie Lee Roeder, Rachel Elizabeth Daum, Sajana Ravi, Emily C. Courtois, Kyle Simtion, Caitlyn Simtion, Cheney E. Merhavy, Zachary I. Merhavy, Teresa C. Frohman, Elliot M. Frohman, Christie Spann

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Neuroprotective role of epigallocatechin-3-gallate, albeginin and melanoxetin in alzheimer's disease by Arif Malik, Mehreen Hassan, Sulayman Waquar, Muhammad Wasim, Anam Naz, Faryal M. Awan, Muhammad T. Khan, Ali I. Khawaja, Sumera Zaib, Jamshed Iqbal, Ayesha Zahid, Marvi Marvi, Javeid Iqbal, Heng Wang, Dong-Qing Wei

“…Purpose: EGCG, is an antioxidant/anti-inflammatory that lowers amyloid-b and tau aggregation in AD models and improves cognition at preclinical dosages of 25–100 mg/kg/day and clinical doses of 200–800 mg/ Albeginin, a new flavonoid, reduces neuroinflammation in rats at 10–50 mg/kg/day, equal to 100–200 mg/day in humans. …”
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Systemic delivery of AAV5, AAV8, and AAV9 packaging a C5-12-microdystrophin-FLAG expression cassette in non-human primates by Mengping Liu, Erica Cook, Yanshan Dai, Erich Ehlert, Francois du Plessis, Jacek Lubelski, Bogdan G. Sleczka, Petia Shipkova, Zhuyin Li, Joshua Gamse, David Gordon, Leonard P. Adam, Paul C. Levesque, Glen B. Banks

“…Non-human primates (NHPs) provide a more accurate assessment of the feasibility of achieving an effective and safe dose than rodents. Here, we compared a single systemic administration of AAV5, AAV8, or AAV9 in NHPs, each packaging the C5-12-microdystrophin-FLAG expression cassette. …”
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Multiomics-based assessment of the impact of airflow on diverse plant callus cultures by June-Sik Kim, Muneo Sato, Mikiko Kojima, Muchamad Imam Asrori, Yukiko Uehara-Yamaguchi, Yumiko Takebayashi, Thi Nhung Do, Thi Yen Do, Kieu Oanh Nguyen Thi, Hitoshi Sakakibara, Keiichi Mochida, Shinjiro Ogita, Masami Yokota Hirai

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Baccaurea ramiflora fruit peel powder supplementation prevented inflammatory cell infiltration, oxidative stress, and fibrosis in carbon tetrachloride (CCl4) administered ovariecto... by Tahsin Zahan, Mirza Alimullah, Ishrat Jahan, Md. Borhan Uddin, Khondker Ayesha Akter, Md. Junaeid Rahman, Shahnaz Siddiqua, Kamrun Nahar Ela, Sakil Amin, Khondoker Shahin Ahmed, Hemayet Hossain, Ferdous Khan, Md Ashraful Alam, Nusrat Subhan

“…Results: The HPLC study of Baccaurea ramiflora fruit peel powder extract revealed the presence of gallic acid, caffeic acid, trans-ferulic acid, rutin hydrate, and rosmarinic acid. …”
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Urinary bacteriophage cooperation with bacterial pathogens during human urinary tract infections supports lysogenic phage therapy by Mahmood Almosuli, Anna Kirtava, Archil Chkhotua, Lia Tsveniashvili, Nina Chanishvili, Sumaiya Safia Irfan, Emily Ng, Hope McIntyre, Adam J. Hockenberry, Robyn P. Araujo, Weidong Zhou, Ngoc Vuong, Barbara Birkaya, Lance Liotta, Alessandra Luchini

“…From a human health perspective, these data suggest that temperate phages may facilitate bacterial infections rather than function as protective agents. These findings support the use of lysogenic phages as therapeutic Trojan Horses.…”
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Targeting adipocyte ESRRA promotes osteogenesis and vascular formation in adipocyte-rich bone marrow by Tongling Huang, Zhaocheng Lu, Zihui Wang, Lixin Cheng, Lu Gao, Jun Gao, Ning Zhang, Chang-An Geng, Xiaoli Zhao, Huaiyu Wang, Chi-Wai Wong, Kelvin W. K. Yeung, Haobo Pan, William Weijia Lu, Min Guan

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Author Correction: Targeting adipocyte ESRRA promotes osteogenesis and vascular formation in adipocyte-rich bone marrow by Tongling Huang, Zhaocheng Lu, Zihui Wang, Lixin Cheng, Lu Gao, Jun Gao, Ning Zhang, Chang-An Geng, Xiaoli Zhao, Huaiyu Wang, Chi-Wai Wong, Kelvin W. K. Yeung, Haobo Pan, William Weijia Lu, Min Guan

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