A novel vasculogenic mimicry-related nomogram predicts prognosis in hepatocellular carcinoma by Yun Zhong, Yun Zhong, Yun Zhong, Yun Zhong, Fadian Ding, Fadian Ding, Fadian Ding, Fadian Ding, Han Zhang, Han Zhang, Han Zhang, Han Zhang, Denghan Zhang, Denghan Zhang, Denghan Zhang, Denghan Zhang, Xiang Zhang, Xiang Zhang, Xiang Zhang, Xiang Zhang, Shangeng Weng, Shangeng Weng, Shangeng Weng, Shangeng Weng

“…Biological process (BP), Kyoto Encyclopedia of Genes and Genomes (KEGG) enrichment analysis, and gene set enrichment analysis (GSEA) were applied to analyze the biological function of the hub genes. …”
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Multiomics insights into BMI-related intratumoral microbiota in gastric cancer by Kang Liu, Zhengchen Jiang, Zhengchen Jiang, Yubo Ma, Ruihong Xia, Yingsong Zheng, Kailai Yin, Chuhong Pang, Li Yuan, Li Yuan, Xiangdong Cheng, Xiangdong Cheng, Zhuo Liu, Bo Zhang, Shi Wang

“…Tumor tissues from 189 GC patients were collected for 16S rRNA sequencing, 64 samples were selected for transcriptome sequencing, and 57 samples were selected for untargeted metabolomic analysis.ResultsClinical cohort analysis revealed that GC patients with a low BMI presented poorer clinical and pathological characteristics than those with a non-low-BMI (NLBMI). …”
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ARID1B Gene Deletion Promotes the Proliferation, Migration and Invasion 
of NSCLC Cells by Linlin ZHU, Xuchao ZHANG

“…Methods Online databases were used to analyze the relationship between ARID1B and the prognosis of patients with lung cancer, and the expression levels of ARID1B in lung cancer tissues. …”
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The Knob Domain of the Fiber-1 Protein Affects the Replication of Fowl Adenovirus Serotype 4 by Xiaofeng Li, Zhixun Xie, You Wei, Zhiqin Xie, Aiqiong Wu, Sisi Luo, Liji Xie, Meng Li, Yanfang Zhang

“…These results demonstrate the role of the knob domain of the fiber-1 (fiber-1-Δ2) protein in FAdV-4 infection and provide a theoretical basis for analyzing the function of the fiber-1 protein of FAdV-4.…”
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Exploring the gut microbiota associated with peripheral nerve invasion in colorectal cancer patients and constructing predictive models by Chuanbin Chen, Qingmin Chen, Shenghai Liu, Guoxi Li, Jiawei Zhao, Jingting Huang, Tianyi Ye, Xinting Yang, Zigui Huang, Zhen Wang, Fuhai He, Mingjian Qin, Chenyan Long, Binzhe Tang, Yongqi Huang, Weizhong Tang, Jungang Liu, Xiaoliang Huang

“…We applied a cell sorting algorithm to convert the transcriptome sequencing data obtained from 8 colorectal cancer patients into a matrix representing immune cell abundance. …”
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The African Initiative for Bioinformatics Online Training in Neurodegenerative Diseases (AI‐BOND): Investing in the next generation of African neuroscientists by Bernard Fongang, Biniyam A. Ayele, Yannick N. Wadop, Emmanuel Epenge, Cyrille D. Nkouonlack, Wepnyu Y. Njamnshi, Xueqiu Jian, Murali Sargurupremraj, Alice B. S. Nono Djotsa, Paul F. Seke Etet, Rebecca Bernal, Abdon Atangana, Jose E. Cavazos, Jayandra Jung Himali, Alfred N. Fonteh, Gladys Maestre, Alfred K. Njamnshi, Sudha Seshadri

“…The training addresses the gap in analyzing neurodegenerative disease data by providing skills and knowledge in genetic epidemiology, biostatistics, and bioinformatics to African students and researchers. …”
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Mitigating Response of <i>SlCSE06</i> Induced by 2-Ethylfuran to <i>Botrytis cinerea</i> Infection by Huilan Ye, Hongdou Gao, Jinnian Li, Linye Lu, Shilan Zheng, Chengxin Wu, Youliang Jin, Chengjuan Cao, Haisheng Zhu, Shuang Liu, Fenglin Zhong

“…In this study, 11 <i>SlCSE</i> family members were identified from the tomato genome using bioinformatics analyses. Public transcriptome databases and RT-qPCR experiments were used to analyze gene expression in tomato tissues, responses to <i>Botrytis cinerea</i> infection, and the temporal characteristics of the response to 2-ethylfuran treatment during infection. …”
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AIM2 activation mediated by RIPK1/3-dependent mitochondrial DNA release drives Aβ1−40-Induced retinal pigment epithelium injury by Xiaoxu Huang, Tongqi Li, Guanran Zhang, Jieqiong Chen, Tong Li, Shiqi Yang, Qiyu Bo, Xiaohuan Zhao, Xiaoling Wan, Xinyue Zhu, Bo Yu, Xiaodong Sun, Junran Sun

“…Aβ1-40-treated ARPE-19 cells and hRPE cells were employed to analyze the regulatory effects of RIPK family on mitochondrial DNA (mtDNA) release and AIM2 pathway activation. …”
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Macrophage Membrane-Coated Liposomes Delivering Vonoprazan Disrupt Mitochondrial Oxidative Phosphorylation in Diffuse Large B-Cell Lymphoma by Wang W, Wang L, Fan Q, Xu J, Li Y, Xu J, Zhao B, Ge D, Xiong L, Wu Y, Zhu Y, Chen M

“…This study constructed a macrophage membrane-coated liposomal formulation (MM-Lipid@Vpz) for the targeted delivery of vonoprazan to combat DLBCL, which enables the evasion of the reticuloendothelial system, ensuring enhanced specificity in tumor targeting.Methods: The vonoprazan was delivered by encapsulating liposomes with pre-isolated macrophage membranes, targeted to DLBCL cells and evaluated for changes in cell function. The cellular transcriptome was collected to analyze the mechanism of drug action. …”
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Identification of <i>Peroxiredoxin</i> (<i>PRX</i>) Genes from Pepper Fruits: Involvement in Ripening and Modulation by Nitric Oxide (NO) by Fátima Ramírez-Mellado, Salvador González-Gordo, José M. Palma, Francisco J. Corpas

“…Among these, only CaPRX1-Cys was not detected in the transcriptome (RNA-Seq) of sweet pepper fruits reported previously. …”
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IL-19 as a promising theranostic target to reprogram the glioblastoma immunosuppressive microenvironment by Gilbert Aaron Lee, Justin Bo-Kai Hsu, Yu-Wei Chang, Li-Chun Hsieh, Yi-Tien Li, Ying Chieh Wu, Cheng-Ying Chu, Yung-Hsiao Chiang, Wan-Yuo Guo, Chih-Chun Wu, Liang-Wei Chen, Hung-Wen Kao, Wan-Li Lin, Li‑Wen Tseng, Ting-Wei Weng, Duen-Pang Kuo, Sho-Jen Cheng, Yung-Chieh Chen, Shiu-Wen Huang, Hsing-Jien Kung, Cheng-Yu Chen

“…Methods We utilized clinical and genomic data from the Taiwan GBM cohort and The Cancer Genome Atlas (TCGA) to analyze RNA sequencing data from patient tumor samples, determining the association of interleukin-19 (Il-19) expression with survival and immunosuppressive activity. …”
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