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Combined metabolome and transcriptome to analyze the regulatory network of key enzymes in the synthesis of senkirkine in Emilia sonchifolia
Published 2025-08-01“…This study applied metabolomics to analyze alkaloid compositions in the plant’s roots, stems, leaves, and flowers. …”
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An integrated approach for analyzing spatially resolved multi-omics datasets from the same tissue section
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The dawn of spatiotemporal transcriptomics
Published 2024-06-01“…We also highlight the recent development of bioinformatics tools to analyze the spatiotemporal transcriptomics data, which contributes to the dynamical and predictive spatiotemporal modeling and deeper biological understanding. …”
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Transcriptomics resources of human tissues and organs
Published 2016-04-01“…Recently, several large‐scale transcriptomics studies have analyzed the expression of protein‐coding genes across tissues. …”
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Integrative transcriptomics and single-cell transcriptomics analyses reveal potential biomarkers and mechanisms of action in papillary thyroid carcinoma
Published 2025-05-01“…This study aims to identify robust transcriptomic biomarkers for PTC diagnosis through integrative bioinformatics approaches and elucidate the cellular mechanisms underlying PTC pathogenesis at single-cell resolution.MethodsBased on the Gene Expression Omnibus (GEO) database, we downloaded PTC-related RNA-seq datasets (GSE3467, GSE3678, GSE33630, GSE65144, and GSE82208) and an scRNA-seq dataset (GSE191288). …”
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Contamination Survey of Insect Genomic and Transcriptomic Data
Published 2024-11-01“…In this study, COI barcodes were used to investigate contamination from insects and mammals in GenBank’s genomic and transcriptomic data across four insect orders. Among the 2796 WGS and 1382 TSA assemblies analyzed, contamination was detected in 32 (1.14%) WGS and 152 (11.0%) TSA assemblies. …”
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Systemic inflammatory responses to repeated and increasing endotoxin challenges in fetal sheep
Published 2025-04-01“…Fetal peripheral blood mononuclear cells (PBMCs) were analyzed for transcriptomic changes and tissue cytokine expression postmortem. …”
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Cadmium Exposure Disrupts Uterine Energy Metabolism and Coagulation Homeostasis During Labor in Institute of Cancer Research Mice: Insights from Transcriptomic Analysis
Published 2025-05-01“…The PPI results were visualized using Cytoscape software and further analyzed, with 18 hub genes (maximum clique centrality score > 10) identified through the MCC algorithm of the Cytohubba plugin. …”
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Analyzing the relationship of RNA and DNA methylation with gene expression
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TRANSCRIPTOMIC DIFFERENCES IN MONOZYGOTIC TWINS WITH OVARIAN CANCER
Published 2022-08-01“…Materials-Methods: In this context, the peripheral blood and ovarian tissues of monozygotic twins who are discordant in terms of ovarian cancer and the other healthy sibling who is a BRCA1 mutation carrier were compared in the study to analyze all RNA molecules transcribed at the genome level using next-generation sequencing technology.Through analyzing the molecules transcribed in the whole genome,the genetic variations underlying the development of ovarian cancer in a high-risk family bearing the BRCA1 mutation but only one of whom was found to have ovarian cancer were examined. …”
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