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Hypoxia inducible factor-dependent upregulation of Agrp in glomus type I cells of the carotid body
Published 2025-02-01“…In this study, utilizing histological and molecular biology techniques, we have identified a significant expression of Agrp mRNA and AgRP peptide production in glomus type I cells within the mouse carotid body (CB). …”
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Protocol for recombinant rabies virus titration by quantitative PCR
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Collagen Modulates the Biological Characteristics of WJ-MSCs in Basal and Osteoinduced Conditions
Published 2022-01-01“…Upon osteoinduction, WJ-MSC-COL underwent osteogenesis by switching on the transcription of BMP6/7 and TGFB3 followed by activation of downstream target genes such as INS, IGF1, RUNX2, and VEGFR2 through p38 signalling. …”
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Interaction of Herbal Compounds with Biological Targets: A Case Study with Berberine
Published 2012-01-01“…Further studies are warranted to elucidate the mechanisms of action of berberine using systems biology approach.…”
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Decitabine Increases the Transcription of <i>RIG-I</i> Gene to Suppress the Replication of Feline Calicivirus and Canine Influenza Virus
Published 2025-01-01“…Developing novel antiviral drugs has always been a significant forefront in biological medicine research. Antiviral drugs can be extracted, purified, and synthesized from various biological sources and by different methods. …”
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CRISPR/Cas13a combined with reverse transcription and RPA for NoV GII.4 monitoring in water environments
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Activating Transcription Factor 5 Promotes Tumorigenic Capability in Cervical Cancer Through the Wnt/β-Catenin Signaling Pathway
Published 2025-01-01“…However, the biological function and precise mechanism of ATF5 in cervical cancer remain unclear. …”
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PIWI proteins and piRNAs: key regulators of stem cell biology
Published 2025-02-01“…In this mini review, we discussed the functional roles of PIWI proteins and their associated small RNAs, piRNAs, in regulating gene expression within stem cell biology. Guided by piRNAs, these proteins transcriptionally and post-transcriptionally repress transposons using mechanisms such as the ping-pong amplification cycle and phasing to protect germline genomes. …”
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The Role of miR-378a in Metabolism, Angiogenesis, and Muscle Biology
Published 2015-01-01“…Embedding in the sequence of this transcriptional regulator of oxidative energy metabolism implies involvement of miR-378a in metabolic pathways, mitochondrial energy homeostasis, and related biological processes such as muscle development, differentiation, and regeneration. …”
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Mina53 catalyzes arginine demethylation of p53 to promote tumor growth
Published 2025-02-01“…Summary: Arginine methylation is a common post-translational modification that plays critical roles in many biological processes. However, the existence of arginine demethylases that remove the modification has not been fully established. …”
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