Feasibility, safety and tolerability of estrogen and/or probiotics for improving vaginal health in Canadian African, Caribbean, and Black women: A pilot phase 1 clinical trial. by Biban Gill, Jocelyn M Wessels, Christina L Hayes, Jenna Ratcliffe, Junic Wokuri, Elizabeth Ball, Gregor Reid, Rupert Kaul, Jesleen Rana, Muna Alkhaifi, Wangari Tharao, Fiona Smaill, Charu Kaushic

“…<h4>Methods</h4>ACB women aged 18-49 from the Greater Toronto Area (GTA) were randomized to one of four study arms: intravaginal estradiol (Estring©; 7.5mg/day); a vaginal probiotic (RepHresh™ Pro-B™) administered twice daily; a combination of Estring© and vaginal RepHresh™ Pro-B™ (twice daily); or the Estring© and oral RepHresh™ Pro-B™ (twice daily), for a duration of 30 days. …”
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Changes in the Fluorescence Tracking of NaV1.6 Protein Expression in a BTBR T+Itpr3tf/J Autistic Mouse Model by Musaad A. Alshammari, Mohammad R. Khan, Fawaz Alasmari, Abdulaziz O. Alshehri, Rizwan Ali, Mohamed Boudjelal, Khalid A. Alhosaini, Abdurahman A. Niazy, Tahani K. Alshammari

“…Using Western blot studies and high-resolution confocal microscopy in the prefrontal frontal cortex (PFC), our data indicate disrupted expression of different isoforms of the voltage-gated sodium channels (NaV) at the AIS, whereas other components of AIS such as ankyrin-G and fibroblast growth factor 14 (FGF14) and contactin-associated protein 1 (Caspr) in BTBR were comparable to those in wild-type control mice. …”
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Impact of strict IGF1 control on quality-of-life scores in patients with acromegaly by Chaitanya Gandhi, Marie-Claire Denis, Daniel Holmes, Juan Rivera, Stan van Uum, Shereen Ezzat, Constance Chik

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Karhunen–Loeve orthogonal decomposition method for problems of EEG assessment of patients with migraine by Egorov, Evgenij Nikolaevich, Zhuravlev, Maksim Olegovich, Runnova, Anastasia Evgenevna, Evstropov, Maksim Arkad`evich, Redzhepova, Alena Садуллаевна

“…It has been shown that there is a relationship between the number of significant modes and the power of the alpha rhythm in electroencephalography signals, and the spatial localization of this effect in the occipital region of the brain can be traced. For the frontal lobe of the brain, significant differences in the distribution of the first mode were demonstrated, assessed for groups of patients with rare and frequent migraine attacks.…”
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Two-Dimensional and Three-Dimensional Biomechanical Factors During 90° Change of Direction are Associated to Non-Contact ACL injury in Female Soccer Players by Stefano Di Paolo, Alberto Grassi, Filippo Tosarelli, Matteo Crepaldi, Laura Bragonzoni, Stefano Zaffagnini, Francesco Della Villa

“… # Study Design Prospective cohort study # Methods Sixteen competitive female football (soccer) players (age 21.4 ± 4.3) performed a series of pre-planned 90° COD tasks. 3D motion data was recorded through 10 stereophotogrammetric cameras and a force platform. 2D frontal and transverse plane joint kinematics were computed through video-analysis from three high-speed cameras. …”
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Longitudinal Assessment of Abnormal Cortical Folding in Fetuses and Neonates With Isolated Non‐Severe Ventriculomegaly by Andrea Urru, Oualid Benkarim, Gerard Martí‐Juan, Nadine Hahner, Gemma Piella, Elisenda Eixarch, Miguel A. González Ballester

“…Findings Our results show significant effects of isolated non‐severe VM (INSVM) compared to healthy controls, with reduced cortical thickness in specific brain regions such as the occipital, parietal, and frontal lobes. Conclusion These findings align with existing literature, confirming the presence of alterations in cortical growth and folding in subjects with isolated non‐severe VM (INSVM) from the fetal to neonatal stage compared to controls.…”
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Retrospective MRI analysis of 418 adult shoulder joints to assess the physiological morphology of the glenoid in a low-grade osteoarthritic population by Marc-Pascal Meier, Lars Erik Brandt, Mark-Tilmann Seitz, Paul Jonathan Roch, Katharina Jäckle, Ali Seif Amir Hosseini, Wolfgang Lehmann, Thelonius Hawellek

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Expression of some circulating microRNAs as predictive biomarkers for prognosis and treatment response in glioblastoma by Elham Ali, Marwa Adel Ahmed, May A. Shawki, Lobna R. Ezz El Arab, Mohamed K. Khalifa, Menha Swellam

“…All investigated miRs were significantly elevated in GBM patients with non-frontal lesions. Only miR-200a showed a significant difference in GBM patients older than 60 years with a tumor size ≥ 5 mm. …”
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Rehabilitation needs screening to identify potential beneficiaries: a scoping review by Carla Sabariego, Wouter De Groote, Melissa Corso, Kent Murnaghan, Antony Duttine

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Chiari malformation with concurrent papilledema: a patient-level meta-analysis of case reports and case series by Alejandro Pando, Daniel J. Valdivia, Daniel A. Brenner, Mohammed Ali Alvi, Hai Sun, James K. Liu, Ira Goldstein

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Retention in the Bukhali trial in Soweto, South Africa: a qualitative analysis using self-determination theory by Shane A Norris, Stephen Lye, Catherine E Draper, Nosibusiso Tshetu, Nokuthula Nkosi

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INTERACTIVE WEB 2.0 TOOLS IN CONTENT AND LANGUAGE INTEGRATED LEARNING by Rinata R. Zaripova, Leila L. Salekhova, Andrew V. Danilov

“…Control group was a classical teaching approach group, which consisted of 25 students, in which Russian language was used and only frontal method was applied. Students in the experimental group (25 students) experienced CLIL approach and used appropriate learning materials related to Web 2.0. …”
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Early one-stage posterior-only surgery for congenital cervicothoracic scoliosis in children: medium- and long-term follow-up by Cefei Zhang, Fuyun Liu, Ke Xu, Weiming Hu, Bing Xia, Yufeng Zhao

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Sacral Stress Fracture following the Bone Union of Lumbar Spondylolysis by Tatsuro Sasaji, Hideki Imaizumi, Hiroyuki Takano, Hideo Saitoh, Taishi Murakami, Ryuichi Kanabuchi, Motohiko Sekiya

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Global Perspectives on Addressing Systemic Issues in Music Therapy Curricula and Healthcare by Amy Clements-Cortés, Melissa Mercadal-Brotons, Hakeem Leonard, Vivian Chan, Gro Trondalen, Tao-Deva Stingl, Thomas Stegemann, Claudia Zanini

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Emotional impact on healthcare providers involved in medical assistance in dying (MAiD): a systematic review and qualitative meta-synthesis by Alexander Simpson, Alireza Bagheri, Saumil Yogendra Dholakia

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Brain local structural connectomes and the subtypes of the medial temporal lobe parcellations by Zhensheng Li, Jie Ma, Hongmin Bai, Bingmei Deng, Jian Lin, Weimin Wang

“…The amygdala connectomes exhibited longer characteristic path length and weaker global efficiency than the ipsilateral hippocampus and parahippocampal connectomes. (2) The hubs of the amygdala connectomes were dispersed across the ventral frontal, olfactory area, limbic, parietal regions and subcortical nuclei, and the hubs the hippocampal connectomes were mainly situated within the limbic, parietal, and subcortical regions. …”
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Changes over Time in Intracranial Air in Patients with Cerebral Air Embolism: Radiological Study in Two Cases by Yoko Kaichi, Shingo Kakeda, Yukunori Korogi, Tomohisa Nezu, Shiro Aoki, Masayasu Matsumoto, Makoto Iida, Kazuo Awai

“…We thought that the embolic source was venous in one patient because CT showed air inflow in cortical veins in the bilateral frontal areas, reflecting air buoyancy. In the other patient, CT showed air inflow into not only the cortical veins but also the bilateral cerebral hemispheres and we thought this to be a paradoxical cerebral air embolism. …”
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Comparison of Effectiveness between Cobalt Chromium Rods versus Titanium Rods for Treatment of Patients with Spinal Deformity: A Systematic Review and Meta-Analysis by Frank D. Shega, HongQi Zhang, Daudi R. Manini, MingXing Tang, ShaoHua Liu

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High-Frequency Power Reflects Dual Intentions of Time and Movement for Active Brain&#x2013;Computer Interface by Jiayuan Meng, Xiaoyu Li, Simiao Li, Xinan Fan, Minpeng Xu, Dong Ming

“…Consequently, compared to the BT sessions, AT sessions led to substantially smaller absolute deviation time behaviourally, along with larger high-frequency event-related desynchronization (ERD) in frontal-motor areas, and significantly improved decoding accuracy of time. …”
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