Sesquiterpenoids from <i>Dysoxylum amooroides</i> Stem Bark: Isolation, Structure Determination, and Cytotoxicity Against MCF-7 Breast Cancer Cells by Latifah Gunawan, Hidayat Nurul Mustofa, Al Arofatus Naini, Desi Harneti, Ace Tatang Hidayat, Nurlelasari Nurlelasari, Rani Maharani, Tri Mayanti, Sofa Fajriah, Khalijah Awang, Mohamad Nurul Azmi, Unang Supratman

“…Guaianediol (1) showed inactive activity with IC50 > 100 µM, alismol (2) showed weak activity with IC50 value of 82.1 µM and spathulenol (3) showed considerable activity with an IC50 value of 15.2 µM. …”
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Inflammatory burden index as a prognostic marker in patients with advanced gastric cancer treated with neoadjuvant chemotherapy and immunotherapy by Jiao-Bao Huang, Zhi-Yong Zhou, Jun Lu, Ji-Yun Zhu, Bin Lai, Sheng-Xun Mao, Jia-Qing Cao

“…The median cycle of neoadjuvant therapy was 4(3-4). The median survival time was 85.1%(1 years), 65.6%(2 years), and 47.4%(3 years).Univariate analysis showed that IBI was an independent risk factor for non-TR(residual tumor cells&gt;50%) (HR=1.08,95%CI:1.00-1.45,p&lt;0.001)and OS(HR=1.04,95%CI:1.03-1.05,p&lt;0.001). …”
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Impact of pharmacist-led educational intervention on knowledge of self-management among asthmatic patients: a prospective cohort study by Ahmad Khan, Saima Mushtaq, Amjad Khan, Nafees Ahmad, Shahzadi Sidra Saleem, Rubina Aman, Shahzadi Sadia Saleem, Ayesha Bibi, Saifullah Mehsud, Ivan R Green, Sheikh Abdur Rashid, Kifayat Ullah Shah

“…This study aims to assess the impact of pharmacist-led educational intervention on knowledge of self-management among asthmatic patients.Design A pre–post cohort study.Setting Outpatient department of a tertiary care hospital affiliated with Quaid-i-Azam University, Pakistan.Participants Approximately 265 adult asthmatic patients selected through a spirometry process, aged ≥18 years, were approached. 240 patients gave consent to participate in the study and were divided into control and treatment groups.Interventions The educational intervention consisted of individual patient counselling using educational material with time varied according to each patient’s comprehension and previous knowledge.Primary and secondary outcome measures Assessment consisted of a 14-item Asthma Self-Management Knowledge Questionnaire (ASMQ) quantifying a patient’s self-management knowledge through an ASMQ score and its change following an educational intervention.Results Disease self-management knowledge was low with an average raw ASMQ score of 4.1 (max 14); which equates to a transformed score of 29.34 (max 100) and the proportion of patients who correctly answered more than 50% of questions were 16.7% preintervention. …”
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Beating-Heart Coronary Artery Bypass grafting (BH-CABG) in patients with End-Stage Renal Disease (ESRD): comparison of the Society of Thoracic Surgeons (STS) predicted risk with ac... by Louis Samuels, Anastasia Arce, Samiat Agunbiade, Suzanne Raws, Afshin Parsikia

“…The mean number of grafts was 2.4 (1–4) and CPB time was 78 min (34–128 min) for the PAD-CAB group. …”
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Macroecological predictors to determine future refuges of Luciobarbus species in the Tigris–Euphrates basin: Rethinking conservation strategies and management by Hadi Khoshnamvand, Seyed Mohsen Mousavi, Asef Darvishi, Kourosh Ahmadi, Amir Naghibi, Karel Janko, Asghar Abdoli, Faraham Ahmadzadeh

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Totally robotic total gastrectomy with D2 lymphadenectomy for gastric cancer via da Vinci Xi platform: Technical details and perioperative outcomes by Chengcai Liang, Jianrong Guo, Guoming Chen, Zhiwei Zhou, Shuqiang Yuan

“…Results: With an estimated blood loss of 100 ​ml, the operation lasted 210 ​min, including an anastomosis time of 36 ​min. …”
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Comparison of ultrasound features and lesion sites in dysfunctional arteriovenous fistula by Yin Wang, Xiao-mei Huang, Yi Zhang, Jingjing Li, Jun Li, Zheng Ye, Yu Peng, Xian-jin Zhang, Na Tang, Wen-wen Qiu, Li Xu

“…The dialysis duration and arteriovenous fistula use time were the highest in the vascular calcification group at 86 (interquartile range: 49–140) and 77 (interquartile range: 49–110) months, respectively. …”
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Gonad Maturation of Clown Loach (Botia macracanthus) in Pond by Irzal Effendi, T. Prasetya, Agus Oman Sudrajat, N. Suhenda, K. Sumawidjaja

“…The fish were fed pellet (32,33% protein) 10% biomass, daily in three times. After 20 days, the broodstocks were implanted by LHRH-a 100 u.g/kg of body weight. …”
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The addition of calcium oxide with different doses in the recirculation system to improve the abalone Haliotis squamata seed production by Eddy Supriyono, Debora Victoria Liubana, Tatag Budiardi, Irzal Effendi

“…The results showed that the best abalone treatment medium with the addition of calcium oxide to increase the abalone seed production was 15 mg/L CaO with 100% survival rate, 31.57±2.82% feed efficiency, and 0.56±0.06%/day specific growth rate.   …”
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Density of bacteria in Limnodrilus sp. culture fertilized by fermented chicken manure by Y. Hadiroseyani, . Nurjariah, D. Wahjuningrum

“…Mud and chicken manure in ratio of 1:1 was applied to container of 100×20×15 cm3.  Fertilization was carried out 2 times daily at the dose of chicken manure 130, 160 and 190 g/container.  …”
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Sexual dimorphism related to growth in climbing perch Anabas testudineus by Rahmat Hidayat, Odang Carman, , Alimuddin

“…Sixty individuals of 45-days old juvenile derived from mating of five pairs broods were randomly picked up and reared individually in 20×20×100 cm3 net cages for 135 days. Fish were fed on commercial feed (30% protein) three times a day at 10% feeding rate. …”
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Dietary Zinc Requirement of Young Giant Gouramy (Osphronemus gouramy, Lac.) by Mia Setiawati, N.R. Azwar, I. Mokoginta, R. Affandi

“…The fishes were fed upon the diets at satiation, three times daily, for 12 weeks. The results indicated no zinc deficiency symptoms in this experiment. …”
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A 22 Billion M⊙ Black Hole in Holmberg 15A with Keck KCWI Spectroscopy and Triaxial Orbit Modeling by Emily R. Liepold, Chung-Pei Ma, Jonelle L. Walsh

“…Aided by the superb sensitivity and efficiency of KCWI at the Keck II Telescope, we have obtained spatially resolved stellar kinematics over a ∼100″ × 100″ contiguous field of H15A for this purpose. …”
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Suicide mortality among individuals in federal prisons compared with the general population: a retrospective cohort study in the USA from 2009 to 2020 by Lauren Brinkley-Rubinstein, Katherine LeMasters, Shabbar Ranapurwala, Mike Dolan Fliss, Michael Forrest Behne, Emilie Duchesneau, Jennifer Lao

“…From 2009 to 2020, the observed suicide rate in prisons increased from 10.57 to 19.01 per 100 000 and the crude suicide rate in the general population increased from 15.41 to 17.26 per 100 000. …”
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Multiple use of preservative-free single dose unit dexamethasone 0.1% eye drops is safe within 24 hours by Marco Rossi, Michael A Thiel, Frank Bochmann, Philipp B Baenninger, Claude Kaufmann, Fabienne C Fierz, Silvan Locher, Lucas Bachmann, Irena Mitrovic, Jeremy P Howell

“…At t10, 13/110 cultures were contaminated (11.8%; p=0.267) and 11/110 at t24 (10.0%; t24 vs t0; p=1.00). In 5 of 21 cases of contaminated drops at t10 and/or t24, the same isolates were cultured from the initial conjunctival swab and the SDU. …”
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卒中恢复期患者心肺适能评估及中高强度有氧训练的可行性、安全性及有效性研究 Feasibility, Safety, and Efficacy of Cardiopulmonary Fitness Assessment and Moderate to High Intensity Aerobic Training for Patients Recovering... by 谢丽娜1，朱杰2，李琴英3，刘承弘3，邓盼墨3，贾杰2，3，4 (XIE Li’na1, ZHU Jie2, LI Qinying3, LIU Chenghong3, DEN Panmo3, JIA Jie2,3,4 )

“…Both groups received conventional rehabilitation therapy (3 hours/day, 5 days/week for 4 weeks). At the same time, the intervention group was added with the moderate to high intensity aerobic training (40 minutes/time, 5 times/week) according to the cardiopulmonary fitness results in accordance with the exercise prescription, and the control group was added with the rehabilitation guidance (rehabilitation education, flexibility training, etc.) for the same duration. …”
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Real-world evaluation of physiotherapist-led exercise prehabilitation and rehabilitation during autologous stem cell transplantation in myeloma: a single-centre experience by Orla McCourt, Joanne Land, Neil Rabin, Kwee Yong, Abi Fisher, Jonathan Sive, Charalampia Kyriakou, Michael K Luong, Alasdair Longden

“…A hybrid service using face-to-face clinical assessments and weekly remotely supervised group exercise, via an online video conferencing platform, in the phase between stem cell harvest and admission (prehabilitation), and from discharge to 100 days post-ASCT (rehabilitation). Functional (6 min walk and timed sit-to-stand tests) and patient-reported outcome measures (European Organization for the Research and Treatment of Cancer Quality of Life Questionnaire (EORTC-C30) and EuroQol EQ5D-5L were assessed at preharvest, preadmission and in the post-ASCT evaluation (day 100) clinic.Results Patients (n=46) with a diagnosis of multiple myeloma referred for ASCT following induction chemotherapy were assessed. …”
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Evaluation of vegetable pigeonpea [Cajanus cajan (L.) Millsp] genotypes for yield stability by J. D. Ojwang, R. Nyankanga, N. V. P. R. G. Ganga Rao, J. Imungi

“…The genotypes were planted in a Randomized Complete Block design (RCBD), replicated three times at all sites. Rainfall at Kiboko and Kabete were supplemented with irrigation, using sprinklers, for a total of 38 times, providing 832 mm of water. …”
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A Lower Bound on the Critical Momentum of an Impurity in a Bose–Einstein Condensate by Hinrichs, Benjamin, Lampart, Jonas

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Synovial Osteo-chondromatosis: in Regards with a Case by Dianarelys Villafuerte Delgado, Mercy Guadalupe Heras Heras, Félix González Pérez

“…It affects one in every 100,000 inhabitants. It is 2 times more frequent in men, and mainly affects large joints: knee (70 %), hip (20 %) and shoulder (19 %). …”
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