JMY powers dendritogenesis and is regulated by CaM revealing a general, critical principle in neuromorphogenesis by Maja Kühne, Anna-Lena Zepernick, Britta Qualmann, Michael Manfred Kessels, Maryam Izadi-Seitz

“…Here, we identify the WH2 domain-based actin nucleator JMY as target of the calcium sensor calmodulin, reveal that JMY is critical for dendritic arbor formation and unravel that JMY’s molecular mechanisms employed in dendritic arborization are depended on Arp2/3 complex interaction, Arp2/3 complex activity and functionality of JMY’s WH2 domains, i.e. on JMY’s abilities to promote actin filament formation. …”
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Mechanistic insights into the recognition of Fe2+ and solvent-driven selectivity of chalcone-based receptors by Ajay Shankar

“…Spectrosc. 287 (2023) 122107; 303 (2023) 123129], this study offers novel insight into the supramolecular recognition of Fe2+ by receptor R1, wherein the conventional chalcone binding strategy is extended. Density Functional Theory (DFT) is used to differentiate the complexation behavior of chalcone-based receptors (R1, R2, R3), revealing key nucleophilic centres, particularly the carbonyl and phenolic oxygen atoms, as primary coordination sites. …”
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Evaluasi Kualitas Layanan terhadap Operator Telekomunikasi: Tinjauan Perspektif Pelanggan by Suryat Handoko, Nilda Tri Putri, Jonrinaldi Jonrinaldi

“…PT Semen Padang is now actively promoting synergies and pursuing the company's performance growth to be able to cope with competition in an increasingly tight and complex cement industry. In order to face this, it is necessary to have adequate human resource management from the company. …”
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Microbial metabolites and immune modulation by Hassan Ghasemi

“…Even lipopolysaccharides (LPS), traditionally regarded as pro-inflammatory, can have nuanced roles; at low doses, they may condition immune cells to adopt a tolerogenic state, highlighting the complexity of microbial metabolite interactions.9 Microbial metabolites significantly influence innate immunity by enhancing the pathogen-clearing abilities of macrophages, as SCFAs optimize their phagocytic functions. …”
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THE OPTIMIZATION METHOD OF FUZZY AUTOMATIC CLASSIFICATION IN THE PROBLEM OF COMBINING THE ASSESSMENTS OF TRAJECTOR MEASUREMENTS IN THE RADAR SYSTEM by A. V. Khizhniak

“…By a radiolocation system the author mean an automated hierarchical technical complex that combines, using communication tools, a set of asynchronously functioning radiolocation tools, as well as central and intermediate points that collect, process and issue trajectory radiolocation information. …”
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BIOLOGICAL RESPONSE OF TREATMENT WITH SAFFRON PETAL EXTRACT ON CYTOKYNE-INDUCED OXIDATIVE STRESS AND INFLAMMATION IN THE CACO-2/THP1 COCOLTURE MODEL

“…Furthermore, the results of our model suggest that SPE treatment restores the functionality of the intestinal barrier by reducing the destruction of tight junctions induced by the inflammatory stimulus. …”
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A new methodology to associate SNPs with human diseases according to their pathway related context. by Burcu Bakir-Gungor, Osman Ugur Sezerman

“…Our methodology is based on functionalization of important SNPs to identify effected genes and disease related pathways. …”
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Depletion reveals role of bicarbonate in the photosynthetic electron transport chain of Limnospira maxima by Leslie Castillo, Stavroula Nicolaou, Colin Gates, Colin Gates

“…Using chlorophyll fast repetition rate fluorometry, it was observed under bicarbonate depletion that oscillations were still present in a fraction of PSIIs, confirming the functionality of the water oxidizing complex remains in this fraction of centers. …”
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VPS4B orchestrates response to nuclear envelope stress by regulating ESCRT-III dynamics in glioblastoma by Zuqian Wu, Issei Omura, Atsushi Saito, Kazunori Imaizumi, Yasunao Kamikawa

“…The Nuclear envelope (NE) is frequently challenged by mechanical stimuli involving cells passing through a tight space and such stress is known as “NE stress.” …”
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Large system study of chalcopyrite and pyrite flotation surfaces based on SCC-DFTB parameterization method by Jianhua Chen, Yibing Zhang

“…In this study, we employed the self-consistent charge density functional tight-binding (SCC-DFTB) parameterization method to develop a parameter set, CuFeOrg, which includes the interactions between Cu-Fe-C-H-O-N-S-P-Zn elements, to investigate the surface interactions in large-scale flotation systems of chalcopyrite and pyrite. …”
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Ste12/Fab1 phosphatidylinositol-3-phosphate 5-kinase is required for nitrogen-regulated mitotic commitment and cell size control. by David Cobley, Lenka Hálová, Marie Schauries, Adrian Kaczmarek, Mirita Franz-Wachtel, Wei Du, Karsten Krug, Boris Maček, Janni Petersen

“…Tight coupling of cell growth and cell cycle progression enable cells to adjust their rate of division, and therefore size, to the demands of proliferation in varying nutritional environments. …”
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Barriers and Strategies for Oral Peptide and Protein Therapeutics Delivery: Update on Clinical Advances by Kshitis Chandra Baral, Ki Young Choi

“…In particular, functional biomaterials, active targeting, and lymphatic transport strategies have provided new platforms for oral PP delivery. …”
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Production, purification and characterization of recombinant, full-length human claudin-1. by Nicklas Bonander, Mohammed Jamshad, Dominik Oberthür, Michelle Clare, James Barwell, Ke Hu, Michelle J Farquhar, Zania Stamataki, Helen J Harris, Karsten Dierks, Timothy R Dafforn, Christian Betzel, Jane A McKeating, Roslyn M Bill

“…The transmembrane domain proteins of the claudin superfamily are the major structural components of cellular tight junctions. One family member, claudin-1, also associates with tetraspanin CD81 as part of a receptor complex that is essential for hepatitis C virus (HCV) infection of the liver. …”
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Duplex γ/α-phase evolution of biocompatible high-nitrogen stainless steel in additive manufacturing by Yufeng Tao, Liansheng Lin, Xudong Ren, Xuejiao Wang, Xia Cao, Yunxia Ye, Erjin Zhang, Heng Gu, Zijie Dai

“…Artificial tunability of microstructured high-nitrogen γ/α duplex-phase at tight topological control promises transformative opportunities not possessed by individual ferrite or austenitic phase, allowing pre-programming mechanics (density, strength, hardness, and tensile properties) for next-generation industrial or implantable biomedical uses requiring complex geometries and multi-functions.…”
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The Interplay of Iron and Lipid Homeostasis in Non-Alcoholic Fatty Liver Disease by Clinton J. Kidman, Cyril D.S. Mamotte, Keea R. Inder-Smith, Mark J. Tobin, Mark J. Hackett, Ross M. Graham

“… The liver is essential for numerous metabolic functions and is the primary site of iron storage and regulation in addition to maintaining critical functions in lipid metabolism. …”
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Defining the Protein Phosphatase 2A (PP2A) Subcomplexes That Regulate FoxO Transcription Factor Localization by Adeline M. Luperchio, Daniel J. Salamango

“…FoxO transactivation activity is tightly regulated by a complex network of signaling pathways and post-translational modifications. …”
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The impact of T cells on immune-related liver diseases: an overview by Yuzo Koda, Ryosuke Kasuga, Nobuhito Taniki, Takanori Kanai, Nobuhiro Nakamoto

“…Liver diseases are closely associated with the immune system. Disruption of the tightly regulated balance between immune activation and tolerance induction leads to the development and worsening of immune-related liver diseases. …”
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Surface enzyme-polymerization endows Janus hydrogel tough adhesion and regenerative repair in penetrating orocutaneous fistulas by Ye Ju, Chunyue Ma, Ling Ding, Mingyue Shi, Xia Wang, Dongbei Wu, Qing Wu, Xingjun Qin, Qigang Wang

“…In male New Zealand rabbit POF models, the JHA demonstrates strong adhesion and fluid-tight sealing, and maintained firm sealing for over 3 days without any decreased signs under a normal diet. …”
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Optimisation of the performance and structure of soluble ball seat metal sealing rings based on response surface by CHEN Zhen, RAN Qingjie, CHEN Nengpeng, WANG Qiaomu

“…Horizontal well fracturing technology, as a core tool for efficient development of tight oil and gas reservoirs, is of strategic significance for enhancing the recovery rate of unconventional oil and gas resources. …”
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Integrated biomimetic bioprinting of perichondrium with cartilage for auricle reconstruction by Litao Jia, Siyu Liu, Luosha Gu, Xiaomin Liu, Kexin Sun, Feiyang Chu, Jinshi Zeng, Wenshuai Liu, Haiyue Jiang, Xia Liu

“…Simulating the anatomical structure of the native auricle designs a sandwich construction model containing bilateral perichondrium and intermediate cartilage, employing a photocrosslinkable acellular cartilage matrix and gelatin bionics matrix microenvironment, applying co-cultured auricular chondrocytes and adipose-derived stem cells creates functional cell populations, designing hatch patterns imitates microscopic arrangement structures, utilizing sacrificial materials forms interlaminar network traffic to enhance the tight connection between layers, and finally, assessing the regenerative quality of the constructs explores their feasibility and stability. …”
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