Novel drug targets for monkeypox: From viral to host proteins by Zhaozhong Zhu, Qin Sun, Yunhai Xu, Youya Niu, Fei Yang, Shuidong Feng

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A novel inverter control strategy for maximum hosting capacity photovoltaic systems in distribution networks using power factor. by Ahmed Alfouly, Mohamed A Ismeil, I Hamdan

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Cost Impact Model of a Novel Multi-mRNA Host Response Assay for Diagnosis and Risk Assessment of Acute Respiratory Tract Infections and Sepsis in the Emergency Department by John E. Schneider, Jonathan Romanowsky, Philipp Schuetz, Ivana Stojanovic, Henry K. Cheng, Oliver Liesenfeld, Ljubomir Buturovic, Timothy E. Sweeney

“…Current diagnostic and prognostic solutions, including procalcitonin, lack required accuracy. A novel blood-based host response test, HostDx™ Sepsis by Inflammatix, Inc., assesses the likelihood of a bacterial infection, the likelihood of a viral infection, and the severity of the condition. …”
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Estimating the Burden of Cost in Chronic Graft-versus-Host Disease: A Human Capital Approach by Chris A. Jones, Luca P. Fernandez, Peter Weimersheimer, Neil A. Zakai, Michael Sharf, Oscar A. Mesa, Christian Peters, Antonio di Carlo, Mitchell C. Norotsky

“…With advances in organ matching and preventing acute graft-versus-host-disease (aGvHD), chronic graft-versus-host disease (cGvHD) following allogeneic hematopoietic stem cell transplantation (HSCT) has become a focus of transplant-related morbidity and mortality. …”
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Purpurin suppresses Salmonella invasion of host cells by reducing the secretion of T3SS-1 effector proteins by Zhenxu Shi, Zhimin Guo, Siqi Li, Chenxiao Jiang, Jianfeng Wang, Xuming Deng, Hongtao Liu, Jiazhang Qiu

“…Therefore, PPR represents a promising antivirulence drug that targets the T3SS of ST and may serve as a hit compound for the development of novel antivirulence drugs for the treatment of ST.…”
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Celebrating the 20th anniversary of the first Xanthomonas genome sequences – how genomics revolutionized taxonomy, provided insight into the emergence of pathogenic bacteria, enabl... by Koebnik, Ralf, Cesbron, Sophie, Chen, Nicolas W. G., Fischer-Le Saux, Marion, Hutin, Mathilde, Jacques, Marie-Agnès, Noël, Laurent D., Perez-Quintero, Alvaro, Portier, Perrine, Pruvost, Olivier, Rieux, Adrien, Szurek, Boris

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Carboxymethyl cellulose assisted reforming of poly acrylic acid co methyl methacrylate composite for wastewater treatment and effective hosting of antimicrobial silver by Ahmed Hamdy, Hassan Nageh, S. A. Hassan, Mohamed A. Mekewi, Atef S. Darwish

“…Abstract Herein, novel polymer composite is fabricated by hybridizing poly (acrylic acid-co-methyl methacrylate) filaments with carboxymethyl cellulose, which efficiently reorients and strictly ties the fibrous chains to form polymeric units of plate-like morphology. …”
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Bioinformatics screening and clinical validation of CircRNA and related miRNA in male osteoporosis by Jiayi Li, Sijia Guo, Qingyun Sun, Ning An, Jisheng Lin, Qi Fei

“…It was ultimately found that three miRNAs were upregulated in MOP, while hsa-circ-9130, novel_circ_0014940 and hsa-circ-0054894 were upregulated, hsa-circ-2484 and novel_circ_0033084 were downregulated in patients with MOP. …”
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Emergence of a novel porcine pestivirus with potential for cross-species transmission in China, 2023 by Li-shuang Deng, Tong Xu, Zhi-wen Xu, Ling Zhu

“…Abstract Pestiviruses, RNA viruses belonging to the Flaviviridae family, have a broad host range. Their pathogenicity varies greatly and they have caused significant economic losses in animal husbandry. …”
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Identification and prioritization of novel therapeutic candidates against glutamate racemase from Klebsiella pneumoniae. by Ankit Kumar, Farah Anjum, Md Imtaiyaz Hassan, Anas Shamsi, Rashmi Prabha Singh

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Staphylococcus aureus blocks host autophagy through circSyk/miR-5106/Sik3 axis to promote progression of bone infection. by Zhihao Chen, Qiyuan Jin, Jinqi Zhong, Zonggang Xie, Qi Chen, Liubing Li, Jijie Li, Chenhao Zhao, Junfeng Wang, Xiaoying Tang, Mingxiao Han, Ru Li, Ziyuan Li, Zelei Tong, Min Wang, Hong Du, Haifang Zhang

“…In summary, this study proposes a novel perspective on the immune escape of S. aureus in bone infections, based on circRNA.…”
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An optimized deep-forest algorithm using a modified differential evolution optimization algorithm: A case of host-pathogen protein-protein interaction prediction by Jerry Emmanuel, Itunuoluwa Isewon, Jelili Oyelade

“…Additionally, the optimized model predicted seven novel host-pathogen interactions. Finally, the model was implemented as a web application which is accessible at http://dfh3pi.covenantuniversity.edu.ng.…”
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A novel roseosiphovirus infecting dinoroseobacter shibae DFL12T represents a new genus by Nana Wei, Longfei Lu, Yingying Li, Bo Ding, Lanlan Cai, Yunlan Yang

“…The phage has a narrow host range and demonstrates a long infection cycle with a latent period of 3.5 h and a burst size of 22 plaque-forming units (PFU cell− 1). …”
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Is It Scaly Anteater or Bat A Real Origin of The 2019-Novel CoV: A Probable Hypothesis? by Salar Ali, Taib Hama-Soor, Muhammed Babakir-Mina, Salvatore Dimonte, Francesco Greco

“…The phylogenetic trees for animal coronaviruses with the novel coronavirus-2019 have been created using a number of available complete protein sequences of envelope (E), membrane (M), nucleocapsid (N) and spike (S) proteins. …”
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Biological characterization of novel Escherichia coli O157:H7 phages and their bacteriostatic effects in milk and pork by Qinghai Ren, Qinghai Ren, Qinghai Ren, Zhiwei Wang, Yichen Ge, Yucui Huang, Wei Zhang, Chunxue Liu, Yubao Li, Shengliang Cao

“…The optimal MOIs of vB_EcoP_SD2 and vB_EcoP_SD6 was 0.1 and 0.01, and temperature range for maintaining activity was 4°C to 55°C. The host range of vB_EcoP_SD2 and vB_EcoP_SD6 was 65% (13/20) and 55% (11/20), which was partially complementary to each other (75%, 15/20). …”
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Novel anti-inflammatory properties of mannose oligosaccharides in the treatment of inflammatory bowel disease via LGALS3 modulation by Yaqi Du, Yan Fan, Xin Li, Fenqin Chen

“…Detailed molecular analyses further demonstrated that these changes in microbiota were associated with modifications in the host’s immune response, particularly through the suppression of key inflammatory pathways and cytokines involved in IBD progression. …”
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Phylogenetic Analysis of Spike and Envelope Proteins for a Number of Bat Coronaviruses for Understanding the Hypothesis of Possible Origin for the Novel 2019- nCoV by Salar Ibrahim Ali

“…Coronavirus Disease 19 (COVID-19) emergence reveals  globally a great health issue and due to the limited information and knowledge on the origin of this novel coronavirus 2019 (2019-nCoV). Therefore, this study aims to investigate the evolution and analysis of molecular epidemiology for both Spike and Envelope proteins of 20 available complete genome sequences of different bat coronaviruses including 2019-nCoV in order to find out which type of bat coronaviruses is more likely to be the origin of this new 2019-nCoV and also multiple amino acid sequences of Envelope protein for all bat coronaviruses were aligned for the purpose of finding the greater probability of novel 2019-nCoV original host   among bat coronaviruses. …”
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Association of Catharanthus yellow mosaic virus and a novel Tomato leaf curl Lucknow betasatellite with papaya leaf curl disease (PaLCD) in India by Priyanka, Yusuf Akhter, Sangeeta Saxena

“…These findings reveal the complexity of PaLCD in this region, characterized by novel viral combinations, and emphasize the urgent need for further research into viral diversity, host interactions, and integrated management strategies to mitigate the disease impact.…”
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Reduction of chickens use to perform in vitro pre-screening of novel anticoccidials by miniaturisation and increased throughput of the current Eimeria tenella compound-screening mo... by Virginia Marugan-Hernandez, Javier Regidor-Cerrillo, Luis Ortega-Mora, Sara Arias-Maroto, Kelsilandia Aguiar-Martins

“…We have developed an in vitro model for the evaluation of potential anticoccidial properties of novel compounds aimed to control chicken coccidiosis, a costly disease for the poultry industry. …”
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Heterogeneities in infection outcomes across species: sex and tissue differences in virus susceptibility by Roberts, Katherine E, Longdon, Ben

“…Species vary in their susceptibility to pathogens, and this can alter the ability of a pathogen to infect a novel host. However, many factors can generate heterogeneity in infection outcomes, obscuring our ability to understand pathogen emergence. …”
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