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    Targeting the hERG1/β1 integrin complex in lipid rafts potentiates statins anti-cancer activity in pancreatic cancer by Claudia Duranti, Jessica Iorio, Valeria Manganelli, Giacomo Bagni, Rossella Colasurdo, Tiziano Lottini, Michele Martinelli, Chiara Capitani, Giulia Boso, Franco Nicolas D’Alessandro, Maurizio Sorice, Andrea Becchetti, Roberta Misasi, Tina Garofalo, Annarosa Arcangeli

    Published 2025-02-01
    “…Treatment with a single chain bispecific antibody—scDb-hERG1-β1—specifically targeting the complex significantly potentiates the effects of both MβCD and statins on intracellular signaling. …”
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    The role of starting knee angle in squat jump force-velocity profiles: interactions with subjects’ strength levels and imputed push-off distance by Xuelin Qin, Beibei Liu, Ruolin Tang, Yan Liu, Amador García-Ramos, Amador García-Ramos

    Published 2025-02-01
    “…F-v profiles were randomly assessed over three sessions, with SJs performed at starting knee angles of 70° (SJ70), 90° (SJ90), and 110° (SJ110), using either the actual HpO specific to each condition or a standardized HpO corresponding to SJ90.ResultsSignificant differences between SJ types were observed for maximum force (F0) and the F-v slope (SJ110 > SJ90 > SJ70). …”
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    Targeting ceramide transfer protein sensitizes AML to FLT3 inhibitors via a GRP78-ATF6-CHOP axis by Xiaofan Sun, Yue Li, Juan Du, Fangshu Liu, Caiping Wu, Weihao Xiao, Guopan Yu, Xiaowei Chen, Robert Peter Gale, Hui Zeng

    Published 2025-02-01
    “…However, whether targeting CERT to induce ceramide accumulation thereby improving AML therapy efficiency remains elusive. …”
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    Oncolytic peptide LTX-315 induces anti-pancreatic cancer immunity by targeting the ATP11B-PD-L1 axis by Meng Wang, Xing Huang, Tingbo Liang, Tianyu Tang, Gang Zhang, Minghao Lu, Zhengtao Hong, Junming Huang, Xiao Zhi

    Published 2022-03-01
    “…Therefore, LTX-315, or the development of ATP11B-targeting drugs, might improve the efficacy of cancer immunotherapy.…”
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    CONSULTA DE SEGUIMENTO DO DISPOSITIVO INTRAUTERINO (DIU) DE COBRE INSERIDO NO PERÍODO PÓS-PARTO E PÓS-ABORTAMENTO IMEDIATO by Rafaela Quintana Domingues, Camila Giugliani, Victor Matheus Santos da Silva

    Published 2025-02-01
    “…Objetivo: Construir e validar tecnologia educativa audiovisual (vídeo), contendo orientações sobre a consulta de seguimento do dispositivo intrauterino (DIU) de cobre pós-parto e pós abortamento, a fim de qualificar a atuação dos profissionais médicos e enfermeiros da Atenção Primária à Saúde (APS). …”
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    DIFERENCIAS EN EL DESEMPEÑO EN UNA TAREA DE PLANIFICACIÓN SEGÚN LA MOTIVACIÓN DE NIÑAS Y NIÑOS PREESCOLARES by Natalia A. Mancini, M. Soledad Segretin, Sebastián J. Lipina, Matías Lopez-Rosenfeld, Eliana Ruetti

    Published 2019-01-01
    “…La planificación es un proceso autorregulatorio involucrado en la creación y mantenimiento de una secuencia de pasos orientados a resolver una tarea. La literatura aborda la asociación entre motivación y procesos autorregulatorios, pero no específicamente considerando una tarea con demandas de planificación. …”
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    Challenges and strategies in meeting urban tree canopy targets: A scenario discovery analysis to guide urban forest planning in new developments by Raymundo Marcos Martinez, Natthanij Soonsawad, Mariana Dias Baptista, Stephen Cook, Guy Barnett, Joseph Chee, Tim Field, Tim Muster

    Published 2025-03-01
    “…With increasing urban populations worldwide, new developments face ambitious tree canopy cover targets to mitigate urban heat, reduce stormwater runoff, support biodiversity, and promote health benefits. …”
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