DÉTENTION PRÉVENTIVE ET SURPOPULATION CARCÉRALE AU MAROC: UNE INADÉQUATION À LA RECHERCHE D’UNE RÉSOLUTION by Mohamed Jaouhar

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Fraxinellone-mediated targeting of cathepsin B leakage from lysosomes induces ferroptosis in fibroblasts to inhibit hypertrophic scar formation by Wei Xu, Hao Lv, Yaxin Xue, Xiaofeng Shi, Shaotian Fu, Xiaojun Li, Chuandong Wang, Danyang Zhao, Dong Han

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Bioassays for the evaluation of the attractiveness of attractive targeted sugar bait (ATSB) against Anopheles mosquitoes in controlled semi-field systems by Frank S. C. Tenywa, Ummi A. Kibondo, Julian Entwistle, Osward Dogan, Mapipi Haruna, Restuta P. Phisoo, Jason Moore, Jane J. Machange, Haji Makame, Frederic Tripet, Pie Müller, Mathias Mondy, Derric Nimmo, Jennifer C. Stevenson, Sarah J. Moore

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Characterizing the Flow and Interaction of Microbubbles in a 2D Capillary Network for Targeted Drug Delivery: A Simulation Study by Sadegh Shurche, Akram Shahidani, Roghaye Bodaghi Hossein Abadi

“…The evaluated network mimics part of a capillary system by comprising multiple bifurcations. …”
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Determining Near Point of Convergence: Exploring a Component of the Vestibular/Ocular Motor Screen Comparing Varied Target Sizes by John D Heick, Curt Bay

“… # Methods Healthy recreational athletes participated in a comparison of 4 commonly used methods of measuring NPC: a 12-point font target, the VOMS (14-point font target), the tip of a black pen, and the Bernell Vergel^TM^ device (9-point font target). …”
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Exploring the multi-targeted mechanism of Saikosaponin A in prostate cancer treatment: a network pharmacology and molecular docking approach by Genbao Zhu, Genbao Zhu, Genbao Zhu, Zhiming Jiang, Niuping Zhu, Niuping Zhu, Donghui Wang, Donghui Wang, Tianpeng Guo, Tianpeng Guo, Yiqing Meng, Yiqing Meng, Yi Zhu, Yi Zhu, Kemeng Tan, Mengxue Hu, Heng Tang, Xuannian Wang, Xuannian Wang

“…Meanwhile, molecular docking between core targets and SSA was performed using Autodock software. …”
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Pooled screening for CAR function identifies novel IL-13Rα2-targeted CARs for treatment of glioblastoma by Douglas A Lauffenburger, Khloe S Gordon, Caleb R Perez, Andrea Garmilla, Maxine S Y Lam, Joey J Y Aw, Anisha Datta, Andrea Pavesi, Michael E Birnbaum

“…We performed selections in primary human T cells expressing a library of 1.3×106 third generation CARs targeting IL-13Rα2, a cancer testis antigen commonly expressed in glioblastoma. …”
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Light-YOLO: a lightweight detection algorithm based on multi-scale feature enhancement for infrared small ship target by Ji Tang, Xiao-Min Hu, Sang-Woon Jeon, Wei-Neng Chen

Subjects: “…Infrared small target detection…”
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Bufalin targets the SRC-3/c-Myc pathway in chemoresistant cells to regulate metastasis induced by chemoresistance in colorectal cancer by Jinbao Chen, Chenqi Wu, Kun Yu, Jinpei Liu, Jiahua Yang, Wei Li, Xiaoxia Tang, Yihai Shi, Ke Xu, Yi Chen, Xiaoyu Qin

“…BU can precisely regulate c-Myc expression by targeting SRC-3 in chemoresistant cells was confirmed by Western blot. …”
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Targeting protein kinase C-α prolongs survival and restores liver function in sepsis: Evidence from preclinical models by Ling Xiong, Dustin Beyer, Na Liu, Tina Lehmann, Sophie Neugebauer, Sascha Schaeuble, Oliver Sommerfeld, Philipp Ernst, Carl-Magnus Svensson, Sandor Nietzsche, Sebastian Scholl, Tony Bruns, Nikolaus Gaßler, Markus H. Gräler, Marc Thilo Figge, Gianni Panagiotou, Michael Bauer, Adrian T. Press

“…Conclusively, our research underscores the significance of PKCα in controlling excretory liver function during inflammation. This suggests that targeting this protein could restore liver function without compromising the immune system, thereby decreasing sepsis mortality and supporting the recent paradigm that the liver is a hub for the host response to infection that might, in the future, result in novel host-directed therapies supporting the current state-of-the-art intensive care medicine in patients with sepsis-associated liver failure.…”
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AI-enhanced 3D-QSAR screening of fragment-based novel designed molecules targeting Phalaris minor ACCase by Bikash Kumar Rajak, Priyanka Rani, Durg Vijay Singh, Nitesh Singh

“…Acetyl-CoA carboxylase (ACCase: EC 6.4.1.2) is a crucial enzyme for fatty acid synthesis in plants, particularly in the Graminae family, making it an ideal target for herbicides aimed at selective weed control in agriculture. …”
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Comprehensive analysis of α2,3-sialyltransferases as prognostic biomarkers and immunotherapy targets in kidney renal clear cell carcinoma by Yuli Jian, Kangkang Yang, Jinjing Li, Ling Tang, Guang Zeng, Xiaoxin Sun, Xiao Yu, Abdullah Al-danakh, Qiwei Chen, Deyong Yang, Shujing Wang

“…These findings underscore the potential of ST3Gal1 and ST3Gal5 as prognostic factors and immunotherapy targets for KIRC.…”
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Spinally targeted paired associative stimulation with high-frequency peripheral component induces spinal level plasticity in healthy subjects by Anna Nätkynmäki, Leena Lauronen, Piia Haakana, Erika Kirveskari, Janne Avela, Anastasia Shulga

“…This provides further evidence for high-PAS as an option for clinical settings to target plasticity at different levels of the corticospinal tract.…”
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4-H Marine Aquarium Project Book: Youth Project Guide to Starting and Maintaining a Saltwater Aquarium System by R. Prudence Caskey

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Integrated high-precision real scene 3D modeling of karst cave landscape based on laser scanning and photogrammetry by Congyuan Zhang, Jianping Chen, Ping Li, Sipeng Han, Jie Xu

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Cell-Sonar, an Easy and Low-cost Method to Track a Target Protein by Expression Changes of Specific Protein Markers by Sabrina Brockmöller, Lara Molitor, Franz Worek, Simone Rothmiller

“…Our protocol illustrates a method to track a target protein by detecting expression changes of user-selected marker proteins that directly or indirectly interact with the target. …”
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La interpretación de enunciados condicionales como bicondicionales y su problemática en la tarea de selección by Miguel López Astorga

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Amentoflavone from Selaginella bryopteris leaf extracts modulate MAPK signaling - Molecular modeling study for therapeutic target analysis by Praveen Mallari, Mashooq Ahmad Bhat

“…Results: Finally, 61 possible human protein targets were established. The network of 56 proteins indicated that MAPK1, MAPK3 and MAPK14 are potential therapeutic targets with 18, 9 and 57 interacting nodes, respectively. …”
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South African Rheumatism and Arthritis Association 2024 guidelines for the use of biologic and targeted synthetic disease-modifying antirheumatic drugs by E van Duuren, J Potts, U Brijlal, S Botha, S Didi, K Makan, M van Dam, K Chinniah, B Hodkinson

Subjects: “…targeted synthetic therapy…”
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Identification of personal factors that influence engagement in cardiac rehabilitation and interventions targeting personal factors: A scoping review protocol. by Hongyu Zhang, Duygu Sezgin

“…It also aims to explore interventions targeting personal factors to increase cardiac rehabilitation engagement. …”
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