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  1. 4381

    Concomitant mortality trends due to obesity and hypertension in the U.S.: a 20-year retrospective analysis of the CDC WONDER database by Rayyan Nabi, Alina Zanub, Muzamil Akhtar, Sohaib Aftab Ahmad Chaudhry, Abdul Raffay Awais, Hanzala Ahmed Farooqi, Sabahat Ul Ain Munir Abbasi, Peter Collins, Tabeer Zahid, Raheel Ahmed, Muhammad Zia Ur Rehman

    Published 2025-07-01
    “…Joinpoint regression was employed to estimate Annual Percent Change (APC) and Average Annual Percent Change (AAPC) in AAMRs, with statistical significance set at p < 0.05. …”
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  2. 4382

    Family Resilience and Its Influencing Factors Among Patients With Lung Cancer Based on Double ABC‐X Theoretical Framework by Ziyi Shen, Yan Fang, Chengcheng Li, Xin Luo, Junling Cui, Yanchang Liu, Jingfang Hong

    Published 2025-04-01
    “…Clinically, interventions targeting these factors might significantly improve family functioning and coping mechanisms, contributing to better patient and family outcomes during cancer treatment and care.…”
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  3. 4383

    Exploring the influence of nurses’ demographics and hospital work environment on medical error reporting practices in Jordan: a cross-sectional study by Anas Husam Khalifeh, Ala’a Dalky, Islam Ali Oweidat, Sajeda Ramadan Abuzaid, Mohammed AlBashtawy

    Published 2024-11-01
    “…Medical error reporting practices positively correlated with the nursing work environment (r=0.807, p&lt;0.01) and negatively correlated with the average number of patients per shift (r=−0.109, p&lt;0.05). …”
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  4. 4384

    Laparoscopic and Endoscopic Cooperative Dissection for Small Gastric Gastrointestinal Stromal Tumor without Causing Injury to the Mucosa by Lei Cao, Kunming Zheng, Honglei Wang, Yongjie Zhao, Zhengduo Yang, Wen Li

    Published 2019-01-01
    “…However, in the ESD group, three patients were transferred to laparoscopic surgery due to intraoperative massive bleeding or intraoperative perforation. No additional targeted chemotherapy drugs for interstitial tumors were prescribed in two groups. …”
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  5. 4385

    Polymer-free β-cyclodextrins and mefenamic acid inclusion complex nanofibers for enhanced drug solubility and biomedical applications by Sonaimuthu Mohandoss, Kuppu Sakthi Velu, Naushad Ahmad, Ramachandran Srinivasan, Prasanta Roy, Prathap Somu

    Published 2025-08-01
    “…These findings highlight their potential as fast-dissolving drug delivery systems, effective antimicrobial agents, and promising candidates for targeted cancer therapy.…”
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  6. 4386

    Trends in carbapenem antibiotics utilization, costs, and market dynamics in Medicaid: a retrospective analysis from 1991 to 2023 by Marwan A. Alrasheed, Abdulrahman A. Alsuhibani

    Published 2025-08-01
    “…Meropenem prescriptions exhibited steady growth, peaking at 53,355 in 2016, with an Average Annual Percent Change (AAPC) of 17.29% (95% CI: 13.97 to 29.71%, p &lt; 0.001). …”
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  7. 4387

    Antimicrobial prescribing patterns among pediatric outpatient encounters in primary healthcare centers in Bujumbura Mairie, Burundi by Audace Manirakiza, Shital Mahindra Maru, David Gitonga Nyamu, Thomas Bizimana, Manassé Nimpagaritse

    Published 2025-08-01
    “…Abstract Background Understanding prescribing patterns is essential for developing targeted interventions to promote rational antimicrobial use. …”
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  8. 4388

    From Narratives to Diagnosis: A Machine Learning Framework for Classifying Sleep Disorders in Aging Populations: The <i>sleepCare</i> Platform by Christos A. Frantzidis

    Published 2025-06-01
    “…Class-wise F1-scores ranged from <b>0.72 to 0.91</b>, with the highest performance observed in classifying <b>normal or improved sleep</b> (F1 = 0.91). The <b>macro average F1-score</b> was <b>0.78</b>, indicating balanced performance across all categories. …”
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  9. 4389

    Discrimination of Radiologists' Experience Level Using Eye-Tracking Technology and Machine Learning: Case Study by Stanford Martinez, Carolina Ramirez-Tamayo, Syed Hasib Akhter Faruqui, Kal Clark, Adel Alaeddini, Nicholas Czarnek, Aarushi Aggarwal, Sahra Emamzadeh, Jeffrey R Mock, Edward J Golob

    Published 2025-01-01
    “…ConclusionsThe effectiveness of the proposed spatiotemporal discretization approach, validated across diverse datasets and various classification metrics, underscores its potential for objective evaluation, informing targeted interventions and training strategies in radiology. …”
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  10. 4390

    A Comprehensive Study of Spatial Distribution, Pollution Risk Assessment, and Source Apportionment of Topsoil Heavy Metals and Arsenic by Honghua Chen, Xinxin Sun, Longhui Sun, Yunce An, Ying Xiao, Jintao Zhang, Yunpeng Hong, Xiaodong Song

    Published 2024-12-01
    “…These findings will assist in the design of targeted policies to reduce the risks of HMs and As in urban soil and offer useful guidelines for soil pollution research in similar regions.…”
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  11. 4391

    Financial burden among older, long‐term cancer survivors: Results from the LILAC study by Theresa A. Hastert, Gregory S. Young, Michael L. Pennell, Tasleem Padamsee, S. Yousuf Zafar, Cecilia DeGraffinreid, Michelle Naughton, Michael Simon, Electra D. Paskett

    Published 2018-09-01
    “…The identification of several socioeconomic, health‐related and demographic predictors of financial burden may suggest targets of intervention to reduce financial burdens. …”
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  12. 4392

    Efficacy and safety of fondaparinux in elective total hip arthroplasty and hip fracture surgery: a systematic review and meta-analysis by Gonzalo Mariscal, Francisco José Tarazona-Santabalbina, Oliver Marin-Peña, Erika Rotavista, Sara Arroyo Martín, María Estrella Fernández de Sevilla, Jesús Gómez-Vallejo

    Published 2025-05-01
    “…Methods This review adhered to PRISMA guidelines. Inclusion criteria targeted studies on hip surgery patients treated with fondaparinux versus placebo or other anticoagulants. …”
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  13. 4393

    Prevalence and characteristics of tobacco use among adults in Kazakhstan: A cross-sectional National Survey by Anel Ibrayeva, Marat Shoranov, Rassulbek Aipov, Adil Katarbayev, Shynar Tanabayeva, Ildar Fakhradiyev

    Published 2025-06-01
    “…Among current smokers, 89.1 % smoked daily, with an average of 11.8 cigarettes per day (95 % CI: 11.4–12.2). …”
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  14. 4394
  15. 4395

    Manipulated Slow Release of Florfenicol Hydrogels for Effective Treatment of Anti-Intestinal Bacterial Infections by Luo W, Zhang M, Jiang Y, Ma G, Liu J, Dawood AS, Xie S, Algharib SA

    Published 2025-01-01
    “…Wanhe Luo,1,2 Mengdi Zhang,1 Yongtao Jiang,1 Guocai Ma,3 Jinhuan Liu,1,4 Ali Sobhy Dawood,5 Shuyu Xie,6 Samah Attia Algharib7 1College of Animal Science and Technology, Tarim University, Alar, Xinjiang, 843300, People’s Republic of China; 2Key Laboratory of Livestock and Forage Resources Utilization Around Tarim, Ministry of Agriculture and Rural Areas, Tarim University, Alar, Xinjiang, 843300, People’s Republic of China; 3Instrumental Analysis Center, Tarim University, Alar, Xinjiang, 843300, People’s Republic of China; 4Lab for Sustainable Antimicrobials, Department of Pharmacy, Sichuan Agricultural University, Chengdu, Sichuan, 610000, People’s Republic of China; 5Medicine and Infectious Diseases Department, Faculty of Veterinary Medicine, University of Sadat City, Sadat city, 32897, Egypt; 6National Reference Laboratory of Veterinary Drug Residues (HZAU) and MARA Key Laboratory for Detection of Veterinary Drug Residues, Huazhong Agricultural University, Wuhan, Hubei, 430070, People’s Republic of China; 7Department of Clinical Pathology, Faculty of Veterinary Medicine, Benha University, Moshtohor, Toukh, 13736, EgyptCorrespondence: Wanhe Luo; Samah Attia Algharib, Email luowanhe0728@163.com; samah.alghareeb@fvtm.bu.edu.egObjective: The difficulty of establishing slow release at intestinal infection sites, weak antibacterial effects, as well as the limited broad use of florfenicol oral formulations are the main targets of the current study. Novel hydrogels derived from sodium alginate were developed using a complexation form for florfenicol delivery to achieve slow release at the site of intestinal infection and enhance its antibacterial activity against Escherichia coli.Methods: The optimal formulation, physicochemical properties, stability, pH-responsive performance, antibacterial activity, and in vitro biosafety of the florfenicol hydrogels have been studied systematically.Results: The created hydrogels had a consistent spherical morphology, with an average diameter of 531.9± 12.6 nm. …”
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  16. 4396

    The burden and trends of gastric cancer from 1990 to 2021 in China and globally: a cross-sectional study by Yulai Yin, Xiaoyu Zhang

    Published 2025-05-01
    “…The findings provide a scientific basis for developing targeted gastric cancer prevention and control policies.MethodsAge-standardized incidence rates (ASIR) and age-standardized mortality rates (ASMR) for gastric cancer from 1990 to 2021 were extracted from the GBD database. …”
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  17. 4397

    Efficacy of complex pathogenic therapy of diabetic distal neuropathy in patients with type 2 diabetes mellitus by Inessa I. Dubinina, Svetlana V. Berstneva, Vadim V. Baranov, Larisa V. Azimkova

    Published 2016-11-01
    “…Furthermore, individual-targeted glycaemic control (HbA1c &lt; 7.5%) was achieved of 78% with consistent reduction in the atherogenicity index. …”
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  18. 4398

    Antihypertensive drug-related problems in Vietnamese ambulatory care by Hoang Hai Nguyen, Le Anh Thu Vu, Minh-Hoang Tran, Hong Tham Pham

    Published 2025-01-01
    “…We conducted a cross-sectional study targeting ambulatory prescriptions of Vietnamese patients with hypertension who either received standard therapy (using two or fewer medications, SdT) or standard plus add-on therapy (using more than two medications, SdT + add-on). …”
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  19. 4399

    Presence of tumor DNA in aqueous humor is correlated with high risk uveal melanoma by Nicole Barwinski, Mael Lever, Philipp Rating, Leyla Jabbarli, Miltiadis Fiorentzis, Nikolaos E. Bechrakis, Dietmar R. Lohmann, Michael Zeschnigk, Claudia H. D. Le Guin

    Published 2025-06-01
    “…DNA was extracted from the ocular fluids and analyzed for the presence of tumor-derived DNA using deep amplicon sequencing targeting mutations in GNAQ and GNA11. This approach achieved an average read depth of 120,000, enabling highly sensitive detection of tumor-specific variants. …”
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  20. 4400

    Analyzing latent categories of stress, anxiety, and depression in medical students: insights into their psychological resilience by Huang Lei, Huang Lei, Jiang Jiaming, Huang Bin, Yuwen Lyu, Liu Junrong, Lawrence T. Lam, Chen Yufei

    Published 2025-06-01
    “…The disharmonious or average family atmosphere were common high-risk factors for high stress, high anxiety and high depression subgroups. …”
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