Predictive factors associated with acute radiation dermatitis in patients with breast cancer: a retrospective cohort study by Rattanaporn Nanthong, Sunanta Tungfung, Kamonwan Soonklang, Wiriya Mahikul

“…Results Among the 635 patients, the average age was 54.2 ± 10.9 years, and 32% were classified as having moderate to severe ARD. …”
Get full text

Analyses of epidemic characteristics and spatiotemporal clustering of influenza in Beihai， Guangxi from 2014 to 2023 by YE Jiaping, ZHOU Wen, LUO Silu, YE Daru, SU Fengzhuo

“…ObjectiveTo analyze the epidemiological characteristics and the pathogen dynamics of influenza in Beihai over the past ten years, and to provide a scientific basis for formulating targeted prevention and control measures.MethodsData for influenza cases, pathogen surveillance, and population statistics from 2014‒2023 were obtained from China Center for Disease Control and Prevention Information System. …”
Get full text

Podcasts in Mental, Physical, or Combined Health Interventions for Adults: Scoping Review by Elizabeth M Dascombe, Philip J Morgan, Ryan J Drew, Casey P Regan, Gabrielle M Turner-McGrievy, Myles D Young

“…Most peer-reviewed published studies (19/26, 73%) and gray literature sources (22/25, 88%) of the podcasts were used within multicomponent interventions, with most targeting physical health outcomes (peer-reviewed publications: 14/26, 54% and gray literature sources: 13/25, 52%). …”
Get full text

Reducing incidence of postoperative acute kidney injury in trauma and orthopaedics patients: a quality improvement project by Huma Naqvi, Sreenadh Gella, Sanat Kulkarni, Thomas Richardson, Alice Green, Radhika Acharya, Arusa Latif, Dakota Johnson

“…Development of postoperative AKI significantly increased length of hospital stay by 7.11 days on average (95% CI: 4.84 to 9.38 days, p<0.001) and risk of 1-year postoperative mortality (OR 3.22, 95% CI: 1.03 to 10.55, p=0.046).Conclusion This project demonstrates that a multifaceted approach targeting modifiable risk factors can reduce incidence of postoperative AKI in T&O patients, which may lead to reduced length of hospital stay and postoperative mortality.…”
Get full text

Genetic testing for diagnosing neurodevelopmental disorders and epilepsy: a systematic review and meta-analysis by Yu-Ming Chang, Yen-Ta Huang, Pei-Chun Lai

“…Within NGS, WES had a higher yield than targeted gene panels (35.3% vs. 23.2% for NDDs; 34.2% vs. 24.0% for epilepsy). …”
Get full text

Global burden of burns among children and adolescents: a trend analysis from the global burden of disease study 2019 by Hao Zhu, Hao Zhu, Ke Wang, Xiong Liu, Jianfeng Ji, Peng Yang, Feng Xu

“…These findings could help guide the development of more targeted strategies to reduce the burn burden in this population.…”
Get full text

Characterisation and synchronisation of a netted software defined radio radar by Ferran Valdes Crespi, Angel Slavov, Matthias Weiß, Peter Knott, Daniel O’Hagan

“…Multistatic radar systems exploit wide spatial diversity to enhance target detection and tracking, albeit with increased complexity when compared to a monostatic configuration. …”
Get full text

A protocol and analysis of year-long simulations of global storm-resolving models and beyond by Daisuke Takasuka, Masaki Satoh, Tomoki Miyakawa, Chihiro Kodama, Daniel Klocke, Bjorn Stevens, Pier Luigi Vidale, Christopher R. Terai

“…We recommend the continuous four seasons from March 2020 to February 2021 as a target period for the intercomparison but with options for many groups to join more flexibly. …”
Get full text

Estimating mineral-associated organic carbon saturation and sequestration potential using MIR spectral based local quantile regression by Longnan Shi, Karen Daly, Sharon O’Rourke

“…Hence, local quantile regression provided a conservative but more feasible MAOC sequestration target, overcoming limitations in global quantile regression and offering a better framework for regional-scale carbon sequestration estimation. …”
Get full text

Interpreting the biological effects of protons as a function of physical quantity: linear energy transfer or microdosimetric lineal energy spectrum? by Fada Guan, Lawrence Bronk, Matthew Kerr, Yuting Li, Leslie A. Braby, Mary Sobieski, Xiaochun Wang, Xiaodong Zhang, Clifford Stephan, David R. Grosshans, Radhe Mohan

“…We and others have used dose-averaged LET (LET d ) as a correlative physical quantity to the relative biological effectiveness (RBE) of proton beams. …”
Get full text

The effectiveness of Rosuvastatin in controlling LDL-C and non-HDL-C levels in hypertensive patients with or without diabetes mellitus by To Anh Tan Le, An Viet Tran, Son Kim Tran, Chau Minh Tran, Dang Khoa Dang Tran, Duy Huu Duong, Toan Hoang Ngo

“…Methods: A cross-sectional descriptive study on 126 primary hypertensive patients (72 hypertensive patients with diabetes and 54 hypertensive patients without diabetes) treated with Rosuvastatin based on cardiovascular risk stratification according to SCORE to assess the efficiency of achieving treatment targets. Results: In hypertensive patients without diabetes (n = 54; 42.9 %), the average age was higher (63.52 ± 8.68 years) and predominantly female (70.4 %) compared to those with diabetes (n = 72; 57.1 %). …”
Get full text

Unprecedented large-scale aquifer recovery through human intervention by Di Long, Yuancheng Xu, Yingjie Cui, Yanhong Cui, James J. Butler, Liang Dong, Longfeng Wang, Dongyong Liu, Yoshihide Wada, Litang Hu, Guoying Bai, Binghua Li, Shufang Wang, Xizhi Nong, Yang Cai, Chunsheng Cheng, Yuhan Mu, Yu Qiao, Jianhua Wang, Hao Wang, Bridget R. Scanlon

“…Our findings demonstrate that rapid, large-scale groundwater recovery is achievable through integrated water management and targeted policy interventions across extensive regions (~130,000 km2).…”
Get full text

Quantifying Spatial variation in environmental and sociodemographic drivers of leptospirosis in the Dominican Republic using a geographically weighted regression model by Beatris Mario Martin, Benn Sartorius, Helen J. Mayfield, Angela M. Cadavid Restrepo, Behzad Kiani, Cecilia Jocelyn Then Paulino, Marie Caroline Etienne, Ronald Skewes-Ramm, Michael de St Aubin, Devan Dumas, Salome Garnier, William Duke, Farah Peña, Gabriela Abdalla, Lucia de la Cruz, Bernarda Henríquez, Margaret Baldwin, Adam Kucharski, Eric J. Nilles, Colleen L. Lau

“…Abstract Spatial variation in drivers of leptospirosis transmission in the Dominican Republic is poorly understood. To inform targeted public health interventions, we aimed to characterise risk factors and drivers of transmission on a fine spatial scale. …”
Get full text

Quantitative Characterization and Prediction of the Binding Determinants and Immune Escape Hotspots for Groups of Broadly Neutralizing Antibodies Against Omicron Variants: Atomisti... by Mohammed Alshahrani, Vedant Parikh, Brandon Foley, Nishank Raisinghani, Gennady Verkhivker

“…The results of this study and the energetic analysis demonstrate excellent qualitative agreement between the predicted binding hotspots and critical mutations with respect to the latest experiments on average antibody escape scores. We argue that the E1 and F3 groups of antibodies targeting binding epitopes may leverage strong hydrophobic interactions with the binding epitope hotspots that are critical for the spike stability and ACE2 binding, while escape mutations tend to emerge in sites associated with synergistically strong hydrophobic and electrostatic interactions.…”
Get full text

Mapping iron content and white matter integrity in the anterior thalamic radiations across Huntington’s disease stages by Montserrat Domingo-Ayllón, Clara Garcia-Gorro, Nadia Rodriguez-Dechicha, Irene Vaquer, Matilde Calopa, Ruth de Diego-Balaguer, Estela Camara

“…These findings highlight the interplay between iron dysregulation and WM disruption in HD, offering potential pathways for early diagnosis and targeted therapeutic strategies.…”
Get full text

Trans‐right ventricle metabolite gradients in obesity highlight multiple metabolic pathways by Hanna M. Knauss, Mythri Ambatipudi, Leah B. Kosyakovsky, Matthew S. Herzig, Jessica K. Wang, Elizabeth E. Liu, Emily S. Lau, Jenna N. McNeill, Xu Shi, Robert E. Gerszten, Naomi M. Hamburg, Gregory D. Lewis, Jeremy M. Robbins, Jennifer E. Ho

“…In this study, 38 individuals with obesity (mean age 58 years, 68% women, average BMI 36.6 kg/m2) underwent invasive right heart catheterization. …”
Get full text

Copper ion diffusion by solid solution treatment advancing GeTe-based thermoelectrics by Yongqi Chen, Meng Li, Xiaodong Wang, Wenyi Chen, Siqi Liu, Min Zhang, Wanyu Lyu, Nanhai Li, Han Gao, Weidi Liu, Xiao-Lei Shi, Zhi-Gang Chen

“…Here, we develop an innovative solid solution doping strategy that enables targeted doping, whereby Cu ions exclusively occupy host lattice sites rather than interstitial sites. …”
Get full text

Crystal structure reveals the hydrophilic R1 group impairs NDM-1–ligand binding via water penetration at L3 by Xiangrui Shi, Huijuan Yang, Yujie Dai, Hui Zhao, Yuhang Li, Yanxi Li, Xin Zhou, Hailong Yan, Qinghua Zhang, Wei Liu

“…This work demonstrates the essential role of hydrophobic interactions in L3-mediated substrate binding and provides a novel strategy for designing L3-targeted NDM-1 inhibitors: maximize hydrophobicity and minimize polar surface area in the L3 contact region to block water penetration, thereby stabilizing the inhibitor-L3 interaction.…”
Get full text

A Personalized Closed-Loop Brain Stimulation Protocol for Difficulty Falling Asleep by Lin Wang, Yue Yu, Shaofei Ying, Mingju Wang, Yun Qin, Tiejun Liu, Dezhong Yao

“…The application of IF-tACS showed preliminary improvements for those with insomnia, significantly reducing deep sleep latency by an average of 8.6 minutes. The stimulation also restore the cortical connectivity that is disrupted at sleep onset. …”
Get full text

Toxin Profiling of <i>Amanita citrina</i> and <i>A. sinocitrina</i>: First Report of Buiotenine Detection by Yi-Zhe Zhang, Yi Yao, Kai-Ping Zhang, Jia-Qi Liang, Jia-Ju Zhong, Zhong-Feng Li, Hai-Jiao Li, Fei Xu

“…<i>sinocitrina</i> with an average content of 2.90 and 1.19–6.70 g/kg (<i>n</i> = 3) in the dried mushrooms, respectively. …”
Get full text