Viral Mimetic Bacterial Outer Membrane Vesicles for Targeting Angiotensin-Converting Enzyme 2 by Ahn G, Yoon HW, Jeong JH, Kim YH, Shin WR, Song MS, Ahn JY

“…Keywords: outer membrane vesicle, antigen 43 autotransporters, targeted delivery vehicle, theranostics, angiotensin-converting enzyme 2…”
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A bibliometric analysis of targeted therapy cardiotoxicity research in cancer patients (2004–2024) by Guoming Chen, Guang Chen, Huiping Zhou, Qingyi Yang, Yifan Shang, Rui Qin, Yingyue Hou, Cheng Zhang, Jiarui Lin, Xuan Ye, Ning Wang, Yibin Feng

“…BackgroundThe management of long-term cardiotoxicity has become increasingly challenging despite the growing utilization of targeted therapies to enhance progression-free and overall survival rates. …”
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A Representation-Learning-Based Graph and Generative Network for Hyperspectral Small Target Detection by Yunsong Li, Jiaping Zhong, Weiying Xie, Paolo Gamba

“…Hyperspectral small target detection (HSTD) is a promising pixel-level detection task. …”
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Sivelestat-Loaded Neutrophil-Membrane-Coated Antioxidative Nanoparticles for Targeted Endothelial Protection in Sepsis by Juexian Wei, Aijia Zhong, Yuting Zhang, Ehua Deng, Hengzong Mo, Hongyu Zhao, Jiayu Huang, Huaidong Peng, Kaiyin Zhang, Xiaohui Chen, Haifeng Mao, Yixin Chen, Yongcheng Zhu

“…<b>Results</b>: The optimized Siv@NMs exhibited an average particle size of approximately 150 nm, and a zeta potential of −10 mV was achieved. …”
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A Vision-Based End-to-End Reinforcement Learning Framework for Drone Target Tracking by Xun Zhao, Xinjian Huang, Jianheng Cheng, Zhendong Xia, Zhiheng Tu

“…The experimental results indicate that our proposed VTD3 reinforcement learning algorithm substantially outperforms conventional PD controllers in drone target tracking applications. Across various target trajectories, the VTD3 algorithm demonstrates a significant reduction in average tracking errors along the X-axis and Y-axis of up to <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mrow><mn>34.35</mn><mo>%</mo></mrow></semantics></math></inline-formula> and <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mrow><mn>45.36</mn><mo>%</mo></mrow></semantics></math></inline-formula>, respectively. …”
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Research on Biological Detection Based on Reflected Light Images of a Porous Silicon Bragg Mirror by Shuangshuang Zhang, Miao Sun, Jianfeng Yang, Zhenhong Jia, Xiaoyi Lv, Xiaohui Huang

“…According to the experimental results, the average gray value variation increases with the increase of the target DNA concentration and becomes a linear relationship in a certain range. …”
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Statins for primary prevention of cardiovascular events in people with HIV: target trial and modelling study by Sarah R Haile, Oliver Senn, Nicola Serra, Eva A Rehfuess, Milo A Puhan, Mona Loutfy, Jennifer E Thorne, Greer A Burkholder, Michael J Silverberg, Raynell Lang, Timothy R Sterling, Vincent C Marconi, Huldrych F Günthard, Sally B Coburn, Gregory M Lucas, Henock G Yebyo, Oliver Langselius, Jonathan A Colasanti, Sonia Napravnik, Maile Karris, Keri N Althoff

“…Objective To evaluate the effectiveness and benefit-harm balance of various statins for the primary prevention of cardiovascular disease in people with HIV.Design Target trial and modelling study.Setting North American AIDS Cohort Collaboration on Research and Design (NA-ACCORD), 1995 to 2019. …”
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Comparison of effectiveness of common targeting heuristics in repetitive transcranial magnetic stimulation treatment of depression by Thomas Frodl, Irene Neuner, Katrin Sakreida, Nicholas T Trapp, Sarah Kreuzer, Ulrike Rubin, Dieter Schnabel, Jana Hovančáková, Alexander T Sack, Timm B Poeppl

“…Routine strategies were previously incrementally refined and compared in terms of anatomical accuracy, but little is known about their impact on clinical outcomes.Objective To assess the impact of three common scalp-based heuristics for magnetic coil positioning on the treatment outcome of rTMS.Methods This retrospective analysis of real-world clinical data involved patients suffering from a major depressive episode (n=94) who received a 4-week course of excitatory rTMS to the left DLPFC. The treatment target (ie, coil position) was either determined at an absolute distance anterior to the motor hotspot (‘6 cm rule’) or defined in reference to the EEG electrode position F3 using a traditional (‘Beam F3’) or optimised (‘Beam F3 Adjusted’) approach.Findings There was no statistically significant difference between the ‘6 cm rule’ and the ‘Beam F3’ method nor between the ‘Beam F3’ and the ‘Beam F3 Adjusted’ method in head-to-head comparisons of averaged per cent change of scores on depression rating scales (all p&gt;0.605) and response rate (all p&gt;0.475).Conclusions Enhancing targeting precision via scalp-based heuristics does not affect treatment outcomes.Clinical implications There is no need for clinicians to switch from their familiar to an ‘advanced’ approach among these common targeting heuristics.…”
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Determining the research institution scientific productivity. The activity experience by N. M. Rakhimova

“…The author solves the following task: to create the Institute profile in the Russian Science Citation Index (RISC), to analyze bibliographical references in petroleum-targeted periodicals for 2009-2013, to identify trends of publication activity and citation dynamics in RISC, to determine an average number of citations per an article. …”
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Analysing EU Countries’ Digital Progress Towards Sustainable Development Goals by Alexandra-Nicoleta Ciucu (Durnoi), Cosmin Alexandru Teodorescu, Vanesa Madalina Vargas, Corina Ioanas

“…The methods used to make predictions are Autoregressive Integrated Moving Average (ARIMA) and Double Exponential Smoothing. …”
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Global, regional, and national burden of anxiety disorders during the perimenopause (1990–2021) and projections to 2035 by Ying Zhang, Ting-Ting Hu, Yong-Ran Cheng, Zhi-Fen Zhang, Jun Su

“…We calculated trends using the estimated average percent change, and future projections were made using the Bayesian age–period–cohort model to estimate disability-adjusted life year trends for anxiety disorders from 2022 to 2035. …”
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Trends in incidence and mortality of nasopharyngeal cancer in China (2004–2018): an age-period-cohort analysis by Xu Chen, Xu Chen, Wei Xia, Zhi-Hui Xu, Ya-Xi Suo, Long Xie

“…However, it underscores the need for targeted interventions among high-risk populations to further reduce the incidence and mortality rates of NPC.…”
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Effect of intramuscular treatment with different iron dextran dosages and non-inferiority study to gleptoferron by Isabel Hennig-Pauka, Martin Ganter, Dirk Bornhorn, Wesley Lyons, Enric Marco, Glen Almond, Bettina Schneider, Lothar Kreienbrock, Ken Steen Pedersen

“…When using a combination product targeting two diseases, an adjustment of the necessary amount of iron to prevent anaemia in the frame of a farm-specific treatment protocol is not possible. …”
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Research and Application of a Multitarget Detection Algorithm Based on Improved YOLOv8 for Indoor Objects by Yanzhen Wang, Wei Wang, Xiaolong Zhou, Xubin Dong, Jianyong Li, Qi Zhao, Xinyu Yang, Yao Wang

“…Finally, the WIoUv3 loss is used instead of the CIoU loss as the localization regression loss function, which reduces the influence of low-quality anchor frames and enhances the M<sc>odel</sc>&#x2019;s focus on global information, thus improving the accuracy of target object detection. After 300 rounds of testing on 3000 data samples, the YOLOv8 - CBW3 algorithm achieves a detection accuracy of 95.11%, a recall of 94.60%, and an average precision of 95.23%, which are improvements of 2.78% and 3.72% in accuracy and recall, respectively, compared with YOLOv8n. …”
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Extracting Pole Characteristics of Complex Radar Targets for the Aircraft in Resonance Region Using RMSPSO_ARMA by Sang Zhou, Huotao Gao, Fangyu Ren

“…Further, the paper investigated the impact of the swarm optimization algorithm on the accuracy of moving average model parameters when obtaining the resonance set at different target aspects. …”
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Adaptive Constant False Alarm Detector Based on Composite Fuzzy Fusion Rules by Yuyao Yang, Chunbo Xiu

“…The simulation experiment results show that the average detection probability of CFKLQ-CFAR is 2.67% and 1.00% higher than that of KLQ-CFAR and the fuzzy logic fusion detector (FUMCA-CFAR) in a multiple-target environment. …”
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A Pilot Study of a Novel Dietary Intervention Targeting Ultra‐Processed Food Intake by Charlotte J. Hagerman, Asher E. Hong, Emma Jennings, Meghan L. Butryn

“…Future research should prioritize behavioral interventions targeting UPF consumption alongside policy changes.…”
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Russian Trial ALGORITHM: Implementation of Combined Antihypertensive and Hypolipidemic Treatment for Clinical Efficacy Achievement in Routine Clinical Practice by D. A. Napalkov

“…According to the results of therapy with combination drugs based on perindopril, 92.7% of patients managed to reach the target BP levels of &lt;140/90 mm Hg. After treatment the average level of systolic BP decreased from 162.94±13.07 mm Hg to 127.80±7.56 mm Hg, and the level of diastolic BP – from 93.43±8.61 mm Hg to 78.54±5.59. …”
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Differences in melting temperatures of degenerated oligonucleotides targetting nitrous oxide reductase (nosZ) genes by Blaž STRES, Boštjan MUROVEC

“…To accommodate various evolutionary changes in target gene sequences in order to detect numerous variants of the same gene in complex microbial communities, the researchers were forced to design degenerated oligonucleotide probes and primers. …”
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Detection of Welding Defects Using the YOLOv8-ELA Algorithm by Yunxia Chen, Yangkai He, Lei Wu

“…Additionally, the first output layer is enhanced with a SimAM attention mechanism to improve the small target recognition. The experimental findings indicate that, at a 0.5 threshold, the YOLOv8-ELA model achieves mean average precision (mAP@0.5) values of 93.3%, 96.4%, and 96.5% for detecting pores, inclusions, and incomplete welds, respectively. …”
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