Melatonin Alleviates LPS-Induced Pyroptotic Cell Death in Human Stem Cell-Derived Cardiomyocytes by Activating Autophagy by Ya Qiu, Yan Ma, Min Jiang, Sulei Li, Jibin Zhang, Haixu Chen, Mengqi Xu, Shan Gao, Lei Tian, Bo Tao, Yabin Wang, Dong Han, Feng Cao

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Adult-onset Langerhans cell histiocytosis with multisystem involvement: A rare case report by Yaman M․ Alahmad, Omar Al Mukdad, Ahmad Huneity, Sarah Sayed, Renan Adam, Alaa Al-Taie

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Sacubitril/Valsartan for Blood Pressure Lowering in Non‐Dialysis‐Dependent Chronic Kidney Disease Stage 3–5 Patients With Hypertension: A Multicenter Clinical Study by Yu Yan, Xiaomin Li, Juan Cao, Jingyuan Cao, Yao Wang, Liang Wang, Jirong Yu, Lianhua Chen, Min Yang, Xinzhong Huang, Lei Shen, Hong Ding, Manzhi Li, Di Yin, Linglin Jiang, Liang Tang, Yujia Jiang, Ling Hu, Jiyi Si, Hui Zhang, Liqin Cui, Xiameng Gu, Kun Hu, Dongxing Mu, Bicheng Liu, Xiaoliang Zhang, Dong Sun, Xin Wan, Bin Wang

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Silica Nanoparticles Loaded With Selenium Quantum Dots Reduce Myocardial Ischemia-Reperfusion Injury by Alleviating Ferroptosis and Mitochondrial Dysfunction by Li T, Yang B, Liu X, Shi D, Wang Z, Chen Y, Shen C

“…Taixi Li,1,* Boshen Yang,1,* Xijian Liu,2 Dongmei Shi,1 Zhixiang Wang,1 Yizhi Chen,1 Chengxing Shen1 1Department of Cardiology, Shanghai Sixth People’s Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, 200233, People’s Republic of China; 2School of Chemistry and Chemical Engineering, Shanghai Frontiers Science Research Center for Druggability of Cardiovascular Noncoding RNA, Shanghai Engineering Technology Research Center for Pharmaceutical Intelligent Equipment, Shanghai University of Engineering Science, Shanghai, 201620, People’s Republic of China*These authors contributed equally to this workCorrespondence: Chengxing Shen, Department of Cardiology, Shanghai Sixth People’s Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, 200233, People’s Republic of China, Email shencx@sjtu.edu.cnPurpose: Myocardial ischemia-reperfusion (IR) injury, a significant challenge in cardiovascular treatment, is primarily driven by ferroptosis and mitochondrial dysfunction. …”
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Estimating the Economic and Clinical Value of Reducing Antimicrobial Resistance to Three Gram-negative Pathogens in Japan by Tetsuya Matsumoto, Oliver Darlington, Ryan Miller, Jason Gordon, Phil McEwan, Takahisa Ohashi, Amer Taie, Akira Yuasa

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Comparison of the Efficiency of Ultraviolet/Zinc Oxide (UV/ZnO) and Ozone/Zinc Oxide (O3/ZnO) Techniques as Advanced Oxidation Processes in the Removal of Trimethoprim from Aqueous... by Moayede Taie, Abdolmajid Fadaei, Mehraban Sadeghi, Sara Hemati, Gashtasb Mardani

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Les premiers outils : où, quand et qui ? by Emmanuelle Pouydebat

“…En 2015, sur le site de Lomekwi, au Kenya, sont mis au jour de très nombreux outils en pierres taillées. Leur datation ? Elles sont âgées de 3,3 millions d’années ! …”
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LBP-CD155 Liposome Nanovaccine Efficiently Resist Colorectal Cancer and Enhance ICB Therapy by Yan Y, Duan T, Xue X, Yang X, Liu M, Ma B, Duan X, Su C

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Influencing Mechanisms of Ecosystem Services on Net Carbon Sink Efficiency and Spatial Differentiation Thereof: A Case Study of the Shanghai Metropolitan Area by Haoyang SONG, Min WANG

“…In addition, the spatial spillover effects of ecosystem services are innovatively revealed according to ecosystem service flow conduction mechanisms.ResultsResearch results are summarized as follows. 1) During the 11 years from the 2010 to 2020, the growth of carbon dioxide emissions in the Shanghai Metropolitan Area gradually slowed down, while the net primary productivity of vegetation continued to increase, and the areas with high carbon emissions and high carbon sinks were partially overlapped; in addition, the net carbon sink efficiency of some core nodes, such as Shanghai City, maintained a steady improvement, effectively driving neighboring cities to reduce carbon emissions and increase carbon sinks; meanwhile, the areas with improved net carbon sink efficiency have some similar characteristics and can be divided into 2 types: areas with high production value, high carbon emissions, and high carbon sinks, and those with medium-high production value, low carbon emissions, and medium-high carbon sinks. 2) The four ecosystem services have significant spatial heterogeneity and relatively stable changes over the 11-year period, with the high values mainly distributed in the southwestern part of the area with high vegetation cover and the area around the Taihu Lake with concentrated water resources, while the low values mainly distributed in the concentrated urban construction areas and near the regional traffic arteries, and the total amount of the four ecosystem services has shown fluctuating characteristics. 3) Regarding the spatial decomposition effects of ecosystem services on net carbon sink efficiency, there are differences in the coefficients, directions and significance of the spatial effects of different ecosystem services. …”
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Hypofractionated radiotherapy combined with a PD-1 inhibitor, granulocyte macrophage-colony stimulating factor, and thymosin-α1 in advanced metastatic solid tumors: a multicenter P... by Jiamin Yu, Li Yin, Wenjie Guo, Qiang Wang, Juying Liu, Lansheng Zhang, Hongxun Ye, Jianhong Xia, Youyou Xia, Jianfeng Wu, Wanwei Wang, Yanguang Yang, Dan Zong, Xia He, Lijun Wang, Hong Jiang

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Evaluation of dried blood spot sampling for real-time PCR malaria diagnostics in a rural setting in Angola by Alejandro Mediavilla, Begoña Febrer-Sendra, Aroa Silgado, Patricia Martínez-Vallejo, Beatriz Crego-Vicente, Arlette Nindia, Carles Rubio Maturana, Lidia Goterris, Joan Martínez-Campreciós, Sandra Aixut, Pedro Fernández-Soto, María Luisa Aznar, Antonio Muro, Inés Oliveira-Souto, Israel Molina, Elena Sulleiro

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