Editorial by Teddy Surya Gunawan

“…Let us embrace these breakthroughs as stepping stones to a brighter, more sustainable future. …”
Get full text

Bioactives and Other Nutritional Components in the Jaggery Production Process by Nisha Pujari, Nirali Dedhia, Sanjay Mahajani, Narendra Shah, Amit Arora

“…Some unreported phenolics and flavonoids, such as isoferulic acid, prunitrin and maritimetin, which are known to have anti-inflammatory properties, were detected in selected NCS samples. In order to retain maximum mineral content in jaggery and to ensure the removal of appropriate amounts of scum, technological upgrades must be studied and the clarification step must be optimized and standardized.…”
Get full text

Study of the diagnostic significance of telomere length in patients with cerebral atherosclerosis by M. S. Yehorova, D. S. Krasnienkov, V. H. Hurianov, V. Ye. Kondratiuk

“…Based on the multifactor regression analysis, the relationship between telomere length and LPVLD, IMC, EF and LV diastolic function was detected in patients at different stages of CA, including type 2 diabetes (AUC = 0.79 (CI 0.69–0.87)).…”
Get full text

SentemQC - A novel and cost-efficient method for quality assurance and quality control of high-resolution frequency sensor data in fresh waters [version 1; peer review: 1 approved,... by Sofie Gyritia Madsen van't Veen, Joachim Audet, Eti Ester Levi, Brian Kronvang, Søren Erik Larsen, Erik Jeppesen, Esben Astrup Kristensen, Anders Nielsen, Thomas Alexander Davidson, Jane Rosenstand Laugesen, Peter Mejlhede Andersen

“…The SentemQC method is computationally efficient and features a six-step user-friendly setup for anomaly detection. The method marks anomalies in data using five moving windows. …”
Get full text

A 56-year-old Patient with Recurrent Refractory Ascites and Abdominal Pain by K. S. Zemlyanukhina, I. N. Tikhonov, M. S. Zharkova, L. M. Tulina, M. A. Tsai, A. S. Tertychnyy, D. A. Svetov, A. S. Tyan

“…The presence of ascites in a patient without signs of independent liver disease and portal hypertension serves as a reason for conducting an extensive differential diagnosis with a step-by-step examination to exclude malignant lesions of the peritoneum, in particular its primary tumor — mesothelioma.…”
Get full text

The Effect of Hearing Aid Amplification on Gait Parameters: A Pilot Study Using Ear-Worn Motion Sensors by Ann-Kristin Seifer, Arne Küderle, Kaja Strobel, Ronny Hannemann, Björn M. Eskofier

“…<b>Background/Objectives</b>: Hearing loss, particularly in older adults, is associated with reduced physical functioning; increased fall risk; and altered gait patterns, including slower walking speed and shorter step length. …”
Get full text

Experimental Evaluation of Dry and Contactless Cleaning Methods for the Production of Digital Vehicle Dashboards by Patrick Brag, Yvonne Holzapfel, Marcel Daumüller, Ralf Grimme, Uwe Mai, Tobias Iseringhausen

“…In the third step, a test rig had to be designed and built to finally carry out the experiments. …”
Get full text

Detour-Straddle 3D-like path planning of unmanned mining truck in open pit mines based on optimized ant colony algorithm by Mingyu GAO, Jiusheng BAO, Yan YIN, Deping HU, Kekun ZHANG, Chenzhong ZHU, Maosen WANG, Kai WANG

“…Then, the initial pheromone distribution of ant colony algorithm is optimized to improve the goal orientation of the algorithm, and the optimal and worst path is considered in the improved pheromone updating strategy to improve the performance and efficiency of path search. Adaptive multi-step movement mode is introduced, and a multi-objective heuristic function is designed to introduce cross-obstacle evaluation. …”
Get full text

Exploring the Potential of ChatGPT in Developing a Virtual Assistant for Prevention and Support in Cases of School Bullying by Rodolfo Mendoza Pinto

“…Although this research focused on the technical functionality of the chatbot, its implementation in students and data analysis of user interactions represent important future steps. …”
Get full text

Highly Stretchable, Self‐Healable, and Conductive Gelatin Methacryloyl Hydrogel for Long‐Lasting Wearable Tactile Sensors by Zhikang Li, Bin Wang, Jijian Lu, Yumeng Xue, Jiaxiang Wang, Boqing Jia, Gengyu Han, Yihe Zhao, Muhammad Afzal Khan Qureshi, Lan Yu, Kang Zhao, Min Li, Ping Yang, Dejiang Lu, Libo Zhao

“…Herein, a highly stretchable, self‐healing, and conductive gelatin methacryloyl (GelMA) hydrogel is developed by incorporating polyvinyl alcohol, N‐(2‐amino‐2‐oxoethyl)‐2‐propenamide, sodium tetraborate, and sodium chloride into GelMA, followed by a two‐step polymerization process. The introduced novel interpenetrating networks, hierarchical hydrogen bonds (weak and strong H‐bonds), and borate ester bonds (BEBs) synergistically improve the mechanical strength, and concurrently function as sacrificial bonds for energy dissipation under deformation. …”
Get full text

Assessing spatial variability of soil macro fauna and tree canopy using fractal theory (Case study: Riparian Forest of Maroon River) by Shaieste Gholami, ehsan sayad, Hamid Taleshi

“…1-Introduction Sustainability and maintenance of riparian vegetation or restoring of degraded sites is critical to sustain inherent ecosystem function and values. There is an increasing recognition of fundamental role of space in population. …”
Get full text

ParticleHolography.jl: Holographic particle measurement in Julia by Dai Nakai, Yohsuke Tanaka

“…This comprehensive software provides an end-to-end processing pipeline encompassing a wide range of functionalities: preprocessing, including background removal and camera calibration; three-dimensional reconstruction through diffraction calculations; particle analysis, including detection and tracking; and result visualization. …”
Get full text

“Cyclic nucleotides in plants: from obscure messengers to central regulators“ by Brygida Świeżawska-Boniecka, Adriana Szmidt-Jaworska

“…For decades, efforts to detect cyclic nucleotides, specifically cyclic adenosine monophosphate (cAMP) and cyclic guanosine monophosphate (cGMP), in plant tissues and to elucidate their functional roles were inconclusive. …”
Get full text

Evaluation of Morphometric Factors on the Distribution of Debris: A Case Study on the Attica Ripples on the South of Paveh- Kermanshah Province, Iran by Mohammad Ahmadi

“…Non-destructive place data were detected at a confidence level of -0.15 p-value> normal. …”
Get full text

Keeping Active with Texting after Stroke (KATS): a single-arm feasibility and acceptability study of a behavioural intervention to promote community-based physical activity after s... by Gozde Ozakinci, Stephan U Dombrowski, Andrew Murphy, Albert Farre, Jenna Breckenridge, Jacqui H Morris, Linda A Irvine, Keith Jenkinson

“…Preintervention and postintervention measures provided preliminary information on step count, functional independence, mental well-being, self-efficacy and quality of life.Results 18 men and 13 women were recruited; three withdrew before intervention commencement. …”
Get full text

Newborn Screening for Metachromatic Leukodystrophy in Tuscany: The Paradigm of a Successful Preventive Medicine Program by Sabrina Malvagia, Alessandra Bettiol, Margherita Porcaro, Massimo Mura, Silvia Funghini, Daniela Ombrone, Giulia Forni, Emanuela Scolamiero, Filippo Coppi, Roberta Damiano, Cristina Cereda, Simonetta Simonetti, Annalisa Lonetti, Marta Daniotti, Anna Caciotti, Amelia Morrone, Valeria Calbi, Francesca Fumagalli, Alessandro Aiuti, Elena Procopio, Renzo Guerrini, Giancarlo la Marca

“…This diagnostic algorithm proved feasible and accurate for early detection of MLD in prospective NBS.…”
Get full text

Study of head and neck squamous cell carcinoma transcriptome after proton therapy by E. D. Jumaniyazova, P. A. Vishnyakova, M. V. Chirkova, E. A. Karpulevich, I. Z. Eremina, K. B. Gordon, A. D. Kaprin, T. H. Fatkhudinov

“…After isolation of 1 μg total RNA for sequencing, libraries were prepared on the Illumina platform using the TruSeq RNA Sample Prep Kit v2 with a 10-cycle enrichment step according to the manufacturer’s recommendations. …”
Get full text

CD248 induces PD-L1 expression on cancer-associated fibroblasts to promote NSCLC immune escape by Zeyang Yang, Xuanyin Wang, Xu Zhu, Xu Zhu, Long Li, Long Li, Xianling Zeng, Jiaming Ren, Jiaming Ren, Lu Wang, Jiangwei Wu, Qiaoling Zhang, Siyu Wang, Maoqin Lu, Juan Zhai, Xinlei Liu, Jing Xiao, Tao Jin, Ying Zhang, Yun Wang, Yun Wang, Jian Zhang, Zhu Zeng, Zhu Zeng, Zhu Zeng, Jieheng Wu, Jieheng Wu, Jieheng Wu, Jieheng Wu, Jieheng Wu

“…BackgroundTumor immune escape is a critical step in tumor progression. Cancer-associated fibroblasts (CAFs) in the tumor microenvironment (TME) express abundant PD-L1 and suppress the functions of CD8+T cells, enablingd immune escape. …”
Get full text

TET3-facilitated differentiation of human umbilical cord mesenchymal stem cells into oligodendrocyte precursor cells for spinal cord injury recovery by Yubo Zhang, Zhibin Peng, Man Guo, Yangyang Wang, Jingsong Liu, Yishu Liu, Mi Li, Tianli Wei, Pengfei Li, Yingwei Zhao, Yansong Wang

“…This study aimed to explore the TET3-mediated one-step induction of HUCMSCs into OPCs. Methods In vitro, HUCMSCs were induced into OPCs following TET3 overexpression. …”
Get full text

An AI-Based Open-Source Software for <i>Varroa</i> Mite Fall Analysis in Honeybee Colonies by Jesús Yániz, Matías Casalongue, Francisco Javier Martinez-de-Pison, Miguel Angel Silvestre, Beeguards Consortium, Pilar Santolaria, Jose Divasón

Get full text