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461
Homogenization of the Probability Distribution of Climatic Time Series: A Novel Algorithm
Published 2025-05-01“…The new method is similar to quantile matching, but section mean values of the probability distribution function (PDF) are compared instead of individual daily values. …”
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462
CREDIT POLICY OF A COMMERCIAL BANK IN CONDITIONS OF UNCERTAINTY OF THE ECONOMIC ENVIRONMENT
Published 2021-11-01“…The study pays attention to the use of analytical tools of the commercial bank’s credit policy as a means of managing its financial and economic security in conditions of uncertainty, which concerns constant monitoring of loan portfolio quality and timely detection of NPLs. It also suggests the sequence of lending steps specifying practical aspects of use of analytical tools of credit policy. …”
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463
Multi-model quantitative MRI of uterine cancers in precision medicine’s era—a narrative review
Published 2025-05-01“…Abstract Purpose This review aims to summarize the current applications of quantitative MRI biomarkers in the staging, treatment response evaluation, and prognostication of endometrial (EC) and cervical cancer (CC). By focusing on functional imaging techniques, we explore how these biomarkers enhance personalized cancer management beyond traditional morphological assessments. …”
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464
Smart diabetes management: remote monitoring and predictive health insights
Published 2025-06-01“…It supports offline functionality for rural or under-resourced areas, and offers intuitive dashboards for patients and healthcare providers, boosting engagement and treatment adherence. …”
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465
Capsule phase microextraction methodology: Applications and future perspective
Published 2025-05-01“…Extraction plays a crucial role in the quantitative analysis of analytes across various matrices, particularly in biological and other complex samples, where accurate detection and determination would be challenging without effective extraction. …”
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466
Periaural Music Player Daily Use Does Not Significantly Influence the Hearing Thresholds
Published 2019-10-01“…The study included three steps: 1. The participants of the study underwent the otoscopy. 2. …”
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467
Isolation and characterization of a novel lytic bacteriophage Pv27 with biocontrol potential against Vibrio parahaemolyticus infections in shrimp
Published 2025-05-01“…Finally, genomic analysis of Pv27 was conducted through whole-genome sequencing, followed by functional annotation of open reading frames (ORFs) and phylogenetic analysis. …”
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468
Characterization of the novel cross-genus phage vB_SmaS_QH3 and evaluation of its antibacterial efficacy against Stenotrophomonas maltophilia
Published 2025-04-01“…Proliferation kinetics, including multiplicity of infection (MOI), adsorption rate, and one-step growth curves, were analyzed. Stability was assessed under various physicochemical conditions. …”
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469
Barriers and facilitators of fetal heart monitoring with a mobile cardiotocograph (iCTG) device in underserved settings: An exploratory qualitative study from Tanzania.
Published 2024-01-01“…It included the following steps: familiarizing with data, generating initial codes, searching for themes, reviewing themes, defining and naming themes, and producing the report.…”
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470
Biodegradation of S-Triazine Herbicides Under Saline Conditions by <i>Paenarthrobacter ureafaciens</i> PC, a New Halotolerant Bacterial Isolate: Insights into Both the Degradative...
Published 2025-03-01“…The strain PC might degrade prometryne through a series of steps, including demethylthiolation, deisopropylamination, deamination, dealkalation, decarboxylation, etc., relying on the relevant functional genes involved in the degradation of s-triazine compounds. …”
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471
Target Selection, Homokaryotic Isolation, and Screening Methods for Gene Editing in the Destructive Global Pathogen, <i>Phytophthora cinnamomi</i>
Published 2025-02-01“…Despite the integration of the <i>nptII</i> gene, the <i>β-cinnamomin</i> sequence in the transformants remained identical to the wild-type sequence, indicating challenges in detecting and achieving targeted gene disruption. This study identifies critical steps for optimising mutagenesis in <i>P. cinnamomi</i>, highlighting the importance of thorough preliminary screening, effective separation of heterokaryotic populations, and the isolation of homokaryotic colonies.…”
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472
Simulation and analysis of a high-k electron-scale turbulence diagnostic for MAST-U
Published 2025-01-01“…Plasma turbulence on disparate spatial and temporal scales plays a key role in defining the level of confinement achievable in tokamaks, with the development of reduced numerical models for cross-scale turbulence effects informed by experimental measurements an essential step. MAST-U is a well-equipped facility having instruments to measure ion and electron scale turbulence at the plasma edge. …”
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473
CD81-guided heterologous EVs present heterogeneous interactions with breast cancer cells
Published 2024-10-01“…Interestingly, the fusion protein-corresponding transcripts present as full-length mRNAs in recombinant EVs could reach orthotopic breast tumors in JIMT-1-xenografted mice, improving our sensitivity in detecting penetrant cargoes in tissue biopsies. Conclusions This study highlights the quantitative aspects underlying the creation of a platform for secreted heterologous EVs and shows the limits of single receptor-ligand interactions behind EV-cell engagement mechanisms, which now become the pivotal step to predict functional tropism and design new generations of EV-based nanovehicles.…”
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474
Characterization of the small RNAs carried by outer membrane vesicles produced by hlyF-positive Shiga toxin-producing Escherichia coli
Published 2025-08-01“…Specific Real Time PCR assays were deployed to detect the small RNAs within OMVs. The EM and NTA characterization confirmed the presence of spherical particles, and showed that a cleaner preparation was obtained after the second step of ultracentrifugation (200.000 x g). …”
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475
Introduction to the Proteomic Analysis of Placentas with Fetal Growth Restriction and Impaired Lipid Metabolism
Published 2024-11-01“…Fetal growth restriction (FGR) is a disorder defined as the failure of a fetus to achieve its full biological development potential due to decreased placental function, which can be attributed to a range of reasons. …”
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476
Vitamin C in Allergy Mechanisms and for Managing Allergic Diseases: A Narrative Review
Published 2025-05-01“…This narrative review consisted of three steps: conducting the search, reviewing abstracts and full texts, and discussing results. …”
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477
Extracting Meso- and Microscale Patterns of Urban Morphology Evolution: Evidence from Binhai New Area of Tianjin, China
Published 2024-10-01“…The framework includes three steps: constructing specific urban morphology datasets, semantic segmentation to extract urban form, and mapping urban form evolution using the Tile-based Urban Change (TUC) classification system. …”
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478
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479
Deep sequencing of yeast and mouse tRNAs and tRNA fragments using OTTR
Published 2025-04-01“…As with other recent tRNA cloning protocols, we find that a subset of nucleotide modifications leave misincorporation signatures in OTTR datasets, enabling their detection without any additional protocol steps. Focusing on tRNA cleavage products, we compare OTTR with several standard small RNA-Seq protocols, finding that OTTR provides the most accurate picture of tRNA fragment levels by comparison to ‘ground truth’ Northern blots. …”
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480
Protocol for genetic dissection of class switch recombination using genome-editing tools
Published 2025-06-01“…We provide optimized guide RNA (gRNA) sequences and describe steps for cytokine activation, electroporation, surface immunoglobulin detection, and data analysis. …”
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