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221
C57BL/6N albino/agouti mutant mice as embryo donors for efficient germline transmission of C57BL/6 ES cells.
Published 2014-01-01“…This strain has a high superovulation response, allows visual detection of chimeric coat color contribution of C57BL/6 ES-cells and provides a simplified breeding format that generates black G1 offspring of pure inbred C57BL/6 background in one step, providing the ideal host for genetically manipulated C57BL/6 ES cells.…”
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222
XPolypNet: A U-Net-Based Model for Semantic Segmentation of Gastrointestinal Polyps With Explainable AI
Published 2025-01-01“…Automated segmentation of gastrointestinal polyps is a critical step in the early detection and prevention of colorectal cancer (CRC), which is one of the most common causes of cancer-related deaths worldwide. …”
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223
Granular analysis of pathways to care and durations of untreated psychosis: A marginal delay model.
Published 2022-01-01“…We present a novel approach to characterize and analyze PTC and demonstrate its value for the design and implementation of early detection efforts.<h4>Methods</h4>Type and date of every encounter, or node, along the PTC were encoded for 156 participants enrolled in the clinic for Specialized Treatment Early in Psychosis (STEP), within the context of an early detection campaign. …”
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224
A novel method for reliably measuring miniature and spontaneous postsynaptic events in whole-cell patch clamp recordings in the central nervous system
Published 2025-06-01“…As a result, solutions for reliably measuring the quantal size in somatic recordings also do not exist. As the first step in proposing and testing a potential solution, we developed and described a novel miniature postsynaptic event detection algorithm as part of our quantal analysis software called “minis”. …”
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225
Safe Switching Model-Free Value Iteration for General Nonlinear Systems
Published 2025-01-01“…Using the initial controller Q-function and the one continuously actualized during learning, the stability of the switching mechanism in closed loop with the system is derived using the Multiple Lyapunov Functions (MLF) framework. …”
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226
Precoding Method Interference Management for Quasi-EVD Channel
Published 2014-01-01“…This approach used for the design of BD precoding matrix can significantly reduce the computational complexity and proposed algorithm can address several optimization criteria, which is achieved by designing the precoding matrices in two steps. In the first step, we use Cholesky decomposition to maximize the sum-of-rate (SR) with the minimum mean square error (MMSE) detection. …”
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227
Gait-based Parkinson’s disease diagnosis and severity classification using force sensors and machine learning
Published 2025-01-01“…It is acknowledged that the early detection of Parkinson’s disease is contingent upon critical parameters, including stride length, stance duration, swing interval, double limb support, step time, and step length. …”
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228
Prediction for Coastal Wind Speed Based on Improved Variational Mode Decomposition and Recurrent Neural Network
Published 2025-01-01“…For outlier detection, statistical methods were employed, followed by a comparative evaluation of three models—LSTM, LSTM-KAN, and Seq2Seq-Attention—for multi-step wind speed forecasting over horizons ranging from 1 to 12 h. …”
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229
Non-convex optimization with using positive-negative moment estimation and its application for skin cancer recognition with a neural network
Published 2024-04-01“…The main problem of using standard optimization methods is the need to change all parameters in same-size steps, regardless of the behavior of the gradient. …”
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230
MRI-Driven Alzheimer’s Disease Diagnosis Using Deep Network Fusion and Optimal Selection of Feature
Published 2024-10-01“…Alzheimer’s disease (AD) is a degenerative neurological condition characterized by cognitive decline, memory loss, and reduced everyday function, which eventually causes dementia. Symptoms develop years after the disease begins, making early detection difficult. …”
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231
Classification of Thyroid Class using ID3 Algorithm and Artificial Neural Network (ANN)
Published 2025-01-01“…This gland, located below the Adam’s apple, is responsible for coordinating various metabolic processes in the body, making its function essential. Early detection of thyroid symptoms is crucial as an initial step in planning the necessary treatments to prevent more severe thyroid-related health risks. …”
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232
Automated classification of epileptic seizures using modified one-dimensional convolution neural network based on empirical mode decomposition with high accuracy
Published 2025-06-01“…Therefore, to help with patients' long-term assessment and treatment, an effective automatic detection system is required. Traditional methods of machine learning require step of feature extraction by manual which leads to time consuming, for it we modified in one-Dimensional convolution neural network architecture for features extraction and features dimension reduction for makes the classification low computational complexity and more accurate.Methods: In this study, we did a comparison between three methods for classification: support vector machine, artificial neural network and one-dimensional convolution neural network. …”
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233
Use of bovine serum albumin might impair immunofluorescence signal in thick tissue samples
Published 2025-07-01Get full text
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234
Sensitivity and Specificity of Three Measures of Intrinsic Capacity in Older People Aged 80 and Over in Nursing Homes
Published 2024-12-01“…To save resources, ICOPE Step 1 can be considered for direct assessment in non-sensory domains. …”
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235
Specificity of Methylation Assays in Cancer Research: A Guideline for Designing Primers and Probes
Published 2010-01-01“…This highlights the critical need for specific primer and probe design to avoid false-positive detection of methylation profiling. The guideline and online web tools that are introduced in this paper might help to perform a successful experiment and to develop specific diagnosis biomarkers by designing right primer pair and probe prior to experimental step.…”
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236
The roles of natural history during ecological research
Published 2025-03-01“…Still, some authors suggest that patient observation of natural history must be valued as ‘an essential first step in the scientific method’. We think that there is a strong connection between ecology and natural history, and thus delve into such relationship to propose that a) natural history observations are necessary for science problematization (i.e., for the detection of meaningful ecological research problems) and, in some specific contexts, for generating low-level or pattern hypotheses. …”
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237
Application of lossless signal transmission technology in piano timbre recognition
Published 2025-06-01“…Next the analog signal is converted into a digital signal through an A/D converter for subsequent digital signal processing and recognition. Accurate detection of DTMF signals is a crucial step in the application of technology in signal processing, which directly affects the effectiveness of timbre recognition. …”
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238
Machine learning with hyperparameter optimization applied in facies-supported permeability modeling in carbonate oil reservoirs
Published 2025-04-01“…On the other hand, highly permeable fractures function as the main flow conduits within such reservoirs. …”
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239
Optimization Algorithm of Neural Network Structure Based on Adaptive Genetic Algorithm
Published 2021-02-01“…The experiment show that the algorithm for traditional neural network algorithm for function fitting better test; on breast_cancer dataset, the accuracy is 97 57% and the detect errors is 2 07%,better than the classical machine learning algorithms…”
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240
Transcription-Coupled Nucleotide Excision Repair: A Faster Solution or the Only Option?
Published 2025-07-01“…Considering that damage detection is the rate-limiting step of overall repair reactions in most cases and that the mechanisms of the initial recognition of modified DNA structure are fundamentally different between TC-NER and GG-NER, it is suggestive to attribute the observed kinetic differences to different damage spectra recognized by the two pathways. …”
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