Rewiring the seizing brain: stem cell grafts as neuromodulatory architects in epilepsy therapy by Zijie Wang, Yanan Ma, Xiqi Hu, Ying Xia

“…Additionally, monitoring post-transplant cell survival and functionality, along with identifying epilepsy-specific biomarkers, will be crucial to refining the precision and safety of stem cell-based therapies.…”
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Navigating challenges in human pluripotent stem cell-derived islet therapy for type 1 diabetes by Mohammed Usama, Mohammed Usama, Ying Deng, Ying Deng, Yiran Chen, Théa Milland, Théa Milland, Mohan Malleshaiah, Mohan Malleshaiah, Mohan Malleshaiah, Yasaman Aghazadeh, Yasaman Aghazadeh, Yasaman Aghazadeh

“…In the past two decades, several tissues have been generated from the differentiation of human pluripotent stem cells (hPSCs) to model development or disease, and for use in drug testing and cell replacement therapies. …”
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Stem cell and CRISPR/Cas9 gene editing technology in Alzheimer’s disease therapy: from basic research to clinical innovation by Cong He, Baojiang Chen, Ciai Yan, Xiaoqing Zhou

“…This paper gives a new multidimensional therapeutic form to AD treatment by exploring the integrated application of stem cell therapy and CRISPR/Cas9 gene editing technology. …”
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Generation of parathyroid glands from pluripotent stem cells by Mayuko Kano

“…Generating PTGs from pluripotent stem cells (PSCs) offers a potential regenerative therapy for this condition. …”
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Lost in translation: pluripotent stem cell‐derived hematopoiesis by Mania Ackermann, Steffi Liebhaber, Jan‐Henning Klusmann, Nico Lachmann

“…This would not only lay the ground for an improved understanding of human embryonic development but would also contribute toward the generation of novel cell types used in cell replacement therapies. In this line, especially the developmental process of mesodermal cells toward the hematopoietic lineage is of great interest. …”
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Treatment of Genetic Diseases: Current Trends in the Development of Biomedical Cell Products by O. A. Rachinskaya, M. A. Vodyakova, E. V. Melnikova, V. A. Merkulov

“…Products based on various types of viable cells, including differentiated cells, stem cells, induced pluripotent cells, as well as cells genetically modified ex vivo, may be developed for the treatment of one and the same disease. …”
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Cell therapy in Sjögren's syndrome: opportunities and challenges by Yangyang Lu, Rongjing Shi, Wenqin He, Qi An, Jingwen Zhao, Xinnan Gao, Baiyan Zhang, Liyun Zhang, Ke Xu, Dan Ma

“…Therefore, identifying methods to regulate immune disorders and repair damaged tissues is imperative. Cell therapy involves the transplantation of autologous or allogeneic normal or bioengineered cells into the body of a patient to replace damaged cells or achieve a stronger immunomodulatory capacity to cure diseases, mainly including stem cell therapy and immune cell therapy. …”
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Mechanical Forces Guide Axon Growth through the Nigrostriatal Pathway in an Organotypic Model by Sara De Vincentiis, Elena Capitanini, Karen Kira, Claudia Dell'Amico, Jun Takahashi, Marco Onorati, Fabian Raudzus, Vittoria Raffa

“…Abstract Reconstructing the nigrostriatal pathway is one of the major challenges in cell replacement therapies for Parkinson's disease due to the lack of enabling technologies capable of guiding the reinnervation of dopaminergic precursors transplanted into the substantia nigra toward the striatum. …”
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Articular Syndrome Characteristics in Children with Mucopolysaccharidosis Type I by Nato D. Vashakmadze, Mikhail M. Kostik, Nataliya V. Zhurkova, Nataliya V. Buchinskaia, Ekaterina Yu. Zakharova, Margarita A. Soloshenko

“…The contractures of shoulder, ulnar, wrist, and small hand joints have been revealed in most patients with Hurler syndrome, regardless of the administered therapy. Hip joints pathology was observed in children who was administered with: enzyme replacement therapy (ERT) — in 46.7% of cases, hematopoietic stem cell transplantation (HSCT) in combination with ERT — in 34.4% of cases. …”
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History of alternative preventive therapies for type 1 diabetes mellitus by T. S. Khobotkova, N. N. Minyailova, O. V. Budnikova, A. V. Vedernikova

“…These therapeutic methods can be conditionally divided into conservative and surgical approaches,  primarily aimed at protecting pancreatic β-cells from immune-mediated destruction. Notable immunotherapeutic agents include antiproliferative agents, systemic immunomodulators, T-cell inhibitors, monoclonal antibodies, autoantigens, various types of stem cells, dendritic cells, and microbiota therapy.Conclusion. …”
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Human umbilical cord vein as a source of osteoblastic cells by Glauce Crivelaro Nascimento, Rayana Longo Bighetti, Geraldo Aleixo da Silva Passos Júnior, Karina Fittipaldi Bombonato-Prado

“… Objective: Regenerative medicine and tissue engineering are searching for novel stem cell based therapeutic strategies that will allow for efficient treatment or even potential replacement of damaged organs. …”
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Utilization of novel systemic therapies for multiple myeloma: A retrospective study of front‐line regimens using the SEER‐Medicare data by Daisuke Goto, Rahul Khairnar, Jean A. Yared, Candice Yong, Dorothy Romanus, Eberechukwu Onukwugha, Julia F. Slejko

“…We identified 2477 symptomatic newly diagnosed patients who were followed for 6 months or more postdiagnosis and treated with systemic therapies but not with stem cell transplantation. Symptomatic patients were identified by evidence of hypercalcemia, renal failure, anemia, or bone lesions (CRAB criteria). …”
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Parkinson's disease motor symptoms rescue by CRISPRa‐reprogramming astrocytes into GABAergic neurons by Jessica Giehrl‐Schwab, Florian Giesert, Benedict Rauser, Chu Lan Lao, Sina Hembach, Sandrine Lefort, Ignacio L Ibarra, Christina Koupourtidou, Malte Daniel Luecken, Dong‐Jiunn Jeffery Truong, Judith Fischer‐Sternjak, Giacomo Masserdotti, Nilima Prakash, Jovica Ninkovic, Sabine M Hölter, Daniela M Vogt Weisenhorn, Fabian J Theis, Magdalena Götz, Wolfgang Wurst

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Advancements and Perspectives in the Bioprosthetic Heart Valve: A Comprehensive Review on Biomaterial Processing and Emerging Polymeric Materials by Hanluo Li, Shenghua Li, Yalan Lei, Ming Sun, Chunlin Wu, Xueli Wang, Shiwen Xiong, Qing Wang, Sini Kang, Song Chen, Xiaoke Shang

“…Emerging strategies involving gene‐editing technologies, stem cell therapies, and tissue engineering hold considerable promise for the development of next‐generation, patient‐specific, and immunotolerant heart valve prostheses. …”
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From CyBorD to dara-CyBorD, ASCT utilization trends in AL amyloidosis: a 15-year analysis by Eli Muchtar, Angela Dispenzieri, Francis K. Buadi, Prashant Kapoor, David Dingli, Taxiarchis V. Kourelis, Wilson Gonsalves, Nelson Leung, Suzanne R. Hayman, Martha Q. Lacy, Mustaqeem Siddiqui, Joselle Cook, Nadine Abdallah, Moritz Binder, Saurabh Zanwar, William Hogan, Rahma Warsame, S. Vincent Rajkumar, Shaji K. Kumar, Morie A. Gertz

“…Abstract: This retrospective analysis examined 15 years of autologous stem cell transplantation (ASCT) for light chain (AL) amyloidosis at the Mayo Clinic (2010-2024). …”
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P88 | REGENERATIVE MEDICINE, REHABILITATION AND CYTO-HISTOCHEMISTRY: RECENT EVALUATIONS OF INTEGRATED TREATMENTS

“…Advanced treatment protocols concentrate your own platelets, growth factors, and stem cells and deliver them precisely (under image guidance) into the site of your injury to support and promote natural healing. …”
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