Spatially resolved gene expression profiling of tumor microenvironment reveals key steps of lung adenocarcinoma development by Yuma Takano, Jun Suzuki, Kotaro Nomura, Gento Fujii, Junko Zenkoh, Hitomi Kawai, Yuta Kuze, Yukie Kashima, Satoi Nagasawa, Yuka Nakamura, Motohiro Kojima, Katsuya Tsuchihara, Masahide Seki, Akinori Kanai, Daisuke Matsubara, Takashi Kohno, Masayuki Noguchi, Akihiro Nakaya, Masahiro Tsuboi, Genichiro Ishii, Yutaka Suzuki, Ayako Suzuki

“…Abstract The interaction of tumor cells and their microenvironment is thought to be a key factor in tumor development. We present spatial RNA profiles obtained from 30 lung adenocarcinoma patients at the non-invasive and later invasive stages. …”
Get full text

Optimization and Modeling of Optical Emission Spatial Coverage from Underwater Multi-Faceted Optical Base Stations by Junjie Shi, Chunbo Ma, Xu Tian, Hanjun Guo, Jun Ao

Get full text

Quantum correlations and spatial localization in trapped one-dimensional ultra-cold Bose–Bose–Bose mixtures by Tran Duong Anh-Tai, Miguel A García-March, Thomas Busch, Thomás Fogarty

“…These results show the emergence of unique ground-state properties related to correlations, coherence and spatial localization stemming from strongly repulsive interactions.…”
Get full text

Method of Measurement Representativeness Assessment for Spatial Conductometric Sensors as Applied to Investigation of Hydrodynamics in Single Phase Flows by A. A. Barinov, V. G. Glavny, S. M. Dmitriev, M. A. Legchanov, A. V. Ryazanov, A. E. Khrobostov

“…The well-known method of spatial conductometry is widely used for hydrodynamical investigations in the frame of validation benchmarks. …”
Get full text

Spatial characteristics of bicycle–motor vehicle crashes in Christchurch, New Zealand: A case-control approach by Thomas Williams, Crile Doscher, Shannon Page

“…This paper aims to examine the risk of bicycle-motor vehicle crashes occurring on a network-wide level in Christchurch, New Zealand, based on the spatial characteristics present in the road environment. …”
Get full text

Joint frequency and DOA estimation using spatial-temporal co-prime sampling with off-grid sources by Wang-han LYU, Hua-li WANG, Shan-xiang MU, Feng LIU

“…A method of joint frequency and direction of arrival (DOA) estimation using spatial-temporal co-prime sam-pling with off-grid sources was proposed to solve the problem of two-dimensional (2D) mismatches of signals.Firstly,the received signal was sampled by spatio-temporal co-prime sampling technique to construct 2D sparse reconstruction model with the filled coarray.Then the frequency mismatch term and angle mismatch term were incorporated into the re-ceived data model.Based on the above modified model,an improved greedy algorithm was presented to obtain the fre-quency mismatch and angle mismatch by estimating the spectrum leakage terms jointly.So the 2D off-grid sources can be corrected to accurate positions.The method can increase the degrees of freedom (DOF) in the space-frequency domain.Moreover,the method has reduced the amount of computation,and it can improve the frequency and DOA estimation accuracy in the meantime.Simulation results demonstrate the correctness and effectiveness of the proposed approach.…”
Get full text

Semiquantum key distribution network protocol with single photons in both polarization and spatial-mode degrees of freedom by YE Tianyu, YE Tengqi, MA Penghui, LI Xia

“…As the preparation, the measurement and the implementation with unitary operations on single photons with polarization and spatial-mode degrees of freedom are all easy to realize under the present technologies, this protocol possesses the good practical feasibility.…”
Get full text

Spatial Distribution Characteristics and Accessibility Analysis of Characteristic Towns in Guangdong Province Based on Ripley’s K Function by Zhenjie Liao, Lijuan Zhang

“…The results show that (1) the characteristic towns in Guangdong Province present the overall spatial distribution characteristics of “the Pearl River Delta region” and the local distribution characteristics of multicore diffusion in “eastern Guangdong” and “western Guangdong”; (2) the spatial distribution of industrial development, cultural tourism type, innovative and creative characteristic towns shows significant agglomeration, whereas the agglomeration characteristics of agricultural service-oriented and commercial and trade circulation-oriented characteristic towns are not significant; (3) population, economy, resources, and location are the main factors affecting the spatial distribution of characteristic towns in Guangdong Province; (4) the overall spatial accessibility of characteristic towns in Guangdong Province is relatively good. …”
Get full text

Immersive Spatial Computing: How Technology Can Improve Science Content Reading and Vocabulary in Elementary Schools by Leonard Annetta, Ashley Johnson, Mark H. Newton, Yvonne Franco

“…This paper provides a literary rationale for technology-enhanced intervention, provides examples of a study conducted to test the efficacy of such an intervention, presents the implications of the study’s findings, and discusses future avenues for how spatial computing might be used in science and literacy instruction in the future.…”
Get full text

Where to refine spatial data to improve accuracy in crop disease modelling: an analytical approach with examples for cassava by Yevhen F. Suprunenko, Christopher A. Gilligan

“…However, the underlying data on spatial locations of host crops that are susceptible to a pathogen are often incomplete and inaccurate, thus reducing the accuracy of model predictions. …”
Get full text

Mobility Privilege and COVID-19: Determinants of a Spatially Differentiated Experience in the Lockdown-ed Delhi Region by Samuel Benkimoun

Get full text

Spatial risk modelling of highly pathogenic avian influenza in France: Fattening duck farm activity matters. by Jean Artois, Timothée Vergne, Lisa Fourtune, Simon Dellicour, Axelle Scoizec, Sophie Le Bouquin, Jean-Luc Guérin, Mathilde C Paul, Claire Guinat

“…In this study, we present a comprehensive analysis of the key spatial risk factors and predictive risk maps for HPAI infection in France, with a focus on the 2016-17 and 2020-21 epidemic waves. …”
Get full text

A conceptual framework for integrating deltaic food systems and spatial design: the case of the Mekong River Delta by Sophia Arbara, Fransje Hooimeijer

“…Findings emphasize the significance of technological milestones and their spatial implications in shaping resource availability, population growth, and climate change. …”
Get full text

GIS-based Spatial Analysis of the Evolution of Residential Developments; A Case-study of Sulaimani city, Iraq by Shaimaa Sarwar Mohammed, Hoshyar Qadir Rasul, Hussein Darweesh  Mohammed

“…Essentially, following the collection of data, processing, review of relevant literature and applied methods, this study draws a timeline for the spatial evolution of the city of Sulaimani in addition to constricting a spatial grid for morphological comparison of different growth stages and analysis on multiple aspects. …”
Get full text

Spatial eco-socio-economic trade-offs inform differentiated management strategies in mega-urban agglomerations by Yuhan Xu, Chen Chen, Weipeng Deng, Linlin Dai, Tianren Yang

“…Abstract Balancing ecological sustainability with socio-economic development presents a significant challenge for mega-urban regions. …”
Get full text

Spatial and Temporal Variations of Water Quality of Mateur Aquifer (Northeastern Tunisia): Suitability for Irrigation and Drinking Purposes by Besma Tlili-Zrelli, Moncef Gueddari, Rachida Bouhlila

“…The present study aims to assess the spatial and temporal variations of the hydrochemical characteristics of Mateur aquifer groundwaters, a crucial water resource in the northeast of Tunisia. …”
Get full text

Spatially resolved atlas of breast cancer uncovers intercellular machinery of venular niche governing lymphocyte extravasation by Xin Wang, Zhanyu Wang, Qijun Liao, Pei Yuan, Junpu Mei, Yin Zhang, Chao Wu, Xiyu Kang, Sufei Zheng, Chenxuan Yang, Jiaxiang Liu, Qingyao Shang, Jiangtao Li, Bingning Wang, Liangyu Li, Hui Liu, Weining Hu, Zhensheng Dong, Jie Zhao, Linying Wang, Tao Liu, Yusheng Den, Chengrui Wang, Lijuan Han, Qianjun Chen, Huanming Yang, Xun Xu, Jie He, Zhen Yue, Nan Sun, Xiaodong Fang, Jianming Ying

“…Abstract Breast cancers present intricate microenvironments comprising heterotypic cellular interactions, yet a comprehensive spatial map remained to be established. …”
Get full text

Habitat preferences and spatial distribution of larvae of Lipara Meigen, 1830 (Diptera: chloropidae) and associated entomofauna in galls by Anna Janicka, Edyta BuczyŃska, Ewa Szczuka, Adam Tarkowski, Paweł BuczyŃski

“…Significant differences were found between the assemblages of Lipara larvae in reed beds in four habitats (meadows, forests, fens, and the littoral zone of water bodies) and the habitat preferences of the species are indicated. The spatial distribution of these species within reed beds was examined and no significant differentiation was found. …”
Get full text

Ambient Air VOC Levels in an Industrial Area of Turkey: Levels, Spatial Distribution, and Health Risk Assessment by Aykan Karademir, Ercan Arpaz, Şenay Çetin Doğruparmak, Gülsün Özgül

“…The seasonal variations, spatial distribution, and health risk assessment of 13 volatile organic compounds (VOCs), particularly benzene, toluene, ethyl benzene, and xylene (BTEX), in the ambient air of Dilovası, a Turkish city with unplanned urbanization, are presented in this study. …”
Get full text

Spatial working memory in a disappearing object task is impaired in female but not male dogs with chronic osteoarthritis by Melissa Smith, Joanna C. Murrell, Michael Mendl

“…This study compared the performance of 20 dogs with chronic pain from osteoarthritis and 21 healthy control dogs in a disappearing object task of spatial working memory. Female neutered osteoarthritic dogs, but not male neutered osteoarthritic dogs, were found to have lower predicted probabilities of successfully performing the task compared to control dogs of the same sex. …”
Get full text