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5041
Cognitive and anti-inflammatory effects of Palmaria palmata in a schizophrenia mouse model: insights into CREB signaling, Iba-1 expression, and CD4+ cell modulation
Published 2025-06-01“…No notable effects were observed in spatial memory, the novel object recognition test (NORT), or anxiety-related behaviors. …”
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5042
Drone mapping links reindeer browsing during an herbivory pulse to divergent vegetation community responses
Published 2025-01-01“…Here, we employed drone surveys to investigate drivers of spatial heterogeneity in vegetation responses to reindeer herbivory by mapping change comprehensively across a landscape at the fine scale inherent to plant-herbivore interactions. …”
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5043
Leveraging computer-aided design and artificial intelligence to develop a next-generation multi-epitope tuberculosis vaccine candidate
Published 2024-12-01“…Comprehensive bioinformatics analyses were conducted to evaluate the physicochemical properties, spatial structure, immunogenicity, molecular dynamics (MD), and immunological characteristics of the MEV. …”
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5044
Experimental study on the influence of shale content in fault zone on fault friction coefficient based on circular shear test
Published 2025-03-01“…By integrating a 3D prediction model of clay content on fault surfaces, the spatial distribution of non-uniform friction coefficients across fault planes was determined. …”
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5045
Developing Transferable Fourier Transform Mid-Infrared Spectroscopy Predictive Models for Buffalo Milk: A Spatio-Temporal Application Strategy Analysis Across Dairy Farms
Published 2025-03-01“…In temporal dimensions, the TS model effectively predicted the samples collected in a contemporaneous period (RPD<sub>V</sub> (Relative Analytical Error of Validation Set) = 3.45). In the spatial dimension, at first, the modeling was conducted using the samples from one farm, and afterward, 30–70% of a sample from another farm was added to the debugging model. …”
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5046
Aerosol particle number concentration, ultrafine particle number fraction, and new particle formation measurements near the international airports in Berlin, Germany – First result...
Published 2024-11-01“…Here, we provide insights into the spatial–temporal variability of PNC measured in 16 schools recruited for Berlin-Brandenburg Air Study (BEAR).The results show that the average PNC in Berlin was 7900 ± 7000 cm−3, consistent with other European cities. …”
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5047
3D printing-biomimetic local stiff niche enhances glycolysis to boost PDAC cell stem-like phenotype via N6-methyladenosine-suppressed YAP1 mRNA decay
Published 2025-10-01“…Bioinformatics, including Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) analysis, of CSCs identified from spatial transcriptomic and single-cell datasets of PDAC lesions exhibited activated mechanical and glycolytic pathways. …”
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5048
South Asia anthropogenic ammonia emission inversion through assimilating IASI observations
Published 2025-07-01“…We employ a newly developed four-dimensional ensemble variational (4DEnVar)-based emission inversion system to conduct the calculations, resulting in monthly ammonia emissions for 2019 at a resolution of 0.5° <span class="inline-formula">×</span> 0.625°. …”
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5049
Winter Oilseed Rape LAI Inversion via Multi-Source UAV Fusion: A Three-Dimensional Texture and Machine Learning Approach
Published 2025-04-01“…Therefore, this study conducted field experiments over two consecutive years (2021–2022) to collect winter oilseed rape LAI ground truth data and corresponding UAV multispectral imagery. …”
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5050
Machine learning analysis of pathological images to predict 1-year progression-free survival of immunotherapy in patients with small-cell lung cancer
Published 2024-02-01“…Hence, we aimed to develop a predictive biomarker of immunotherapy efficacy through a machine learning analysis of the TIME.Methods We conducted a biomarker analysis in a prospective study of patients with extensive-stage SCLC who received chemoimmunotherapy as the first-line treatment. …”
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5051
Building evidences in Public Health Emergency Preparedness (“BePHEP” Project)—a systematic review
Published 2025-02-01“…Methods A comprehensive literature search was conducted across Scopus, PubMed, and Web of Science, adhering to the PRISMA guideline and the SPIDER framework to identify relevant studies. …”
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5052
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5053
DINOV2-FCS: a model for fruit leaf disease classification and severity prediction
Published 2024-12-01“…For the problem that the model ignores the fine spots in the segmentation process, we propose Explicit Feature Fusion Architecture (EFFA) and Alterable Kernel Atrous Spatial Pyramid Pooling (AKASPP), which improve the segmentation effect of the model.ResultsTo verify the accuracy and generalizability of the model, two sets of experiments were conducted. …”
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5054
Belonging: a meta-theme analysis of women’s community-making in group antenatal and postnatal care
Published 2025-02-01“…Results from this analysis expose that women actively participate in community building in group care in three key ways: (1) Collective agreements, (2) Boundary setting and (3) Care Gestures, orchestrated via socio-spatial building embedded in key pillars of the model. …”
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5055
Study of Multivariate Background Error Characteristics of Convective System on Plateau Slope and Typhoon System Based on Convective-Scale Ensemble Samples
Published 2025-06-01“…The effective assimilation of observation data in the slope areas of the Qinghai-Xizang (Tibetan) Plateau and typhoon systems has a significant impact on the capabilities of weather forecasting in China, with background error being a key factor affecting the performance of data assimilation.The purpose of this study is to gain a deeper understanding of the characteristics of background errors in conventional control variables and hydrometeor control variables within convective systems on the slopes of the Qinghai-Xizang (Tibetan) Plateau and typhoon systems, so as to develop the data assimilation scheme which is applicable to the convective systems on the slopes of the Qinghai-Xizang (Tibetan) Plateau and typhoon systems.This study employs the Ensemble Transform Kalman Filter (ETKF) and the hybrid Ensemble-Variational data assimilation method to update the ensemble perturbation and the ensemble mean respectively to produce convective-scale ensemble forecast samples with 80 ensemble members and 4-kilometers resolution.This study focuses on cases of convective weather from the northeast slope of the Qinghai-Xizang (Tibetan) Plateau in mid-August 2022 and Typhoon "Meihua", the 12th typhoon of 2022.Multivariate background error covariances, including those for multiphase hydrometeor and vertical velocity, were computed through physical transformation, vertical transformation, and horizontal transformation.Analyses of the spatial error characteristics, including the eigenvalues, eigenvectors, and characteristic length scales were conducted, and the results of the analyses indicate that background errors are more pronounced in the case of convective system on the slope of the Qinghai-Xizang (Tibetan) Plateau in comparison to the typhoon system.At the same time, the simulation of hydrometeor variables and vertical velocity is less precise in the case of convective system on the slope of the Qinghai-Xizang (Tibetan) Plateau compared to the typhoon system.In the context of data assimilation for these comparable convective systems, the analysis tends to be more aligned with observations and less so with the background, this feature highlights the necessity for high-quality and comprehensive observations in the slope areas of the Qinghai-Xizang (Tibetan) Plateau.In addition, the atmospheric characteristics and the horizontal scale of hydrometeor variables and vertical velocity in the case of convective system on the slope of the Qinghai-Xizang (Tibetan) Plateau display smaller and more localized features compared with those observed in the typhoon system.Moreover, hydrometeor control variables and the vertical velocity exhibit smaller horizontal scales and more pronounced localized characteristics compared to conventional control variables, therefore potentially leading to the influence range of observations and information related to hydrometeor control variables in the slope areas of the Qinghai-Xizang (Tibetan) Plateau relatively limited in the context of the subsequent assimilation analysis.…”
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5056
Histological validation of three-dimensional variable flip angle turbo spin echo multi-contrast magnetic resonance vessel wall imaging in characterizing carotid vulnerable atherosc...
Published 2024-01-01“…Spearman’s correlation analysis was also conducted to assess the agreement in quantifying plaque compositions. …”
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5057
Dog demography and ecology with reference to rabies in the Amhara region, Ethiopia
Published 2025-01-01“…Knowledge of domestic dog ecology and demography has been recognized as central to the design of an effective rabies control program. The study was conducted to assess owned dogs' ecology and demography and to identify predictors associated with dog ownership and rabies occurrence in the Amhara region, Ethiopia. …”
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5058
Community knowledge, attitude, and practice, incidence of suspected cases, and epidemiological distribution of rabies in humans and animals in Southwest Shewa zone, Oromia, Ethiopi...
Published 2025-04-01“…Despite its importance in public health, no systematic study has been conducted in the area. Therefore, this study aimed to assess the knowledge, attitude, and practice and to estimate the incidence and spatial distribution of rabies in humans and animals in the Southwest Shewa zone of Oromia, Ethiopia.MethodsA questionnaire-based cross-sectional and retrospective study designs were employed among 422 randomly selected informants potentially at risk of rabies. …”
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5060
In situ estimation of active dispersal abilities in reef fish early life stages using tracking technologies
Published 2025-04-01“…Although biophysical models of dispersal ease the development of informed conservation strategies at large spatial scales, comparisons with genetic connectivity demonstrate that only models incorporating realistic active behaviors yield comparable outputs. …”
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