Genome-wide identification, characterization, and expression analysis of BZR transcription factor family in Gerbera hybrida by Qishan Luo, Gan Huang, Xiaohui Lin, Xiaojing Wang, Yaqin Wang

“…Analysis of cis-acting elements revealed their involvement in hormone response, stress response, and growth regulation. …”
Get full text

A ribodepletion and tagging protocol to multiplex samples for RNA-seq based virus detection: application to the cassava virome by Daniel H. Otron, Justin S. Pita, Murielle Hoareau, Fidèle Tiendrébéogo, Jean-Michel Lett, Pierre Lefeuvre

“…In several cassava-growing regions, the co-existence of species and strains from these two families results in a complex epidemiological situation making it difficult to correctly identify the viruses in circulation and delaying the implementation of disease management schemes. …”
Get full text

Non-inferiority study to compare the efficacy of relugolix with dienogest for endometriosis-associated pain and usefulness of administering relugolix prior to dienogest (READY stud... by Fuminori Taniguchi, Motoko Fukui, Yutaka Osuga, Tasuku Harada, Jo Kitawaki

“…A gonadotropin-releasing hormone (GnRH) agonist may also be used to ease symptoms, but may induce flare-ups. …”
Get full text

Oral phenotype and scoring of vascular Ehlers–Danlos syndrome: a case–control study by Lisa Golmard, Ariane Berdal, François Côme Ferré, Michael Frank, Bruno Gogly, Adrien Naveau, Hafida Chérifi, Joseph Emmerich, Frédérick Gaultier, Xavier Jeunemaitre, Benjamin P J Fournier

Get full text

Community perceptions of community health worker effectiveness: Contributions to health behaviour change in an urban health district in South Africa by L S Thomas, Y Pillay, E Buch

“…Nearly all the study households were poor and had at least one vulnerable member, either a child under 5, an elderly person, a pregnant woman or someone with a chronic condition. CHWs had supported these households for 2 years or longer. …”
Get full text

Green nanoparticles synthesized from damask rose petals: Evaluation of their antioxidant, antimicrobial, anti-diabetic, anti-Alzheimer, and photocatalytic properties by Zeinab Alizadeh, Mohammad Fattahi, Alireza Farokhzad, Behvar Asghari, Soheil Yousefzadeh-Valendeh, Hadi Alipour, Javier Palazon

“…The ability of nanoparticles to inhibit the growth of two bacteria Escherichia coli and Staphylococcus aureus showed that G-ZnO NPs displayed the highest inhibition rate against bacterial growth for both strains. Finally, the inhibitory effect of ZnO NPs on α-glucosidase and acetylcholinesterase enzymes was examined, revealing significant inhibition. …”
Get full text

Evaluation of the effect of Irritrol as final irrigant against Staphylococcus epidermidis: an in Vitro Study. by Hezha Saadi Hassan, Diyar Khalid Bakr

“…All of the samples were infected with standard strains of Staphylococcus Epidermidis. Samples were randomly divided into five groups, and five teeth were put as a control group to be compared to the samples after disinfection. …”
Get full text

Revisiting teacher educators' training in Ethiopia: Implications for a new approach to curriculum development by Haftu Hindeya Gebremeskel, Ahmed Yibrie Ahmed, Dawit Asrat Getahun, Meskerem Lechissa Debele, Dawit Tibebu, Dereje Taye Wondem

“…They reported they have sufficient subject matter knowledge but in pure disciplines that are not very much relevant for someone who pursues a career as a teacher educator. …”
Get full text

A single-nucleus RNA sequencing atlas of the postnatal retina of the shark Scyliorhinus canicula by Nicolás Vidal-Vázquez, Ismael Hernández-Núñez, Pablo Carballo-Pacoret, Sarah Salisbury, Paula R. Villamayor, Francisca Hervas-Sotomayor, Xuefei Yuan, Francesco Lamanna, Céline Schneider, Julia Schmidt, Sylvie Mazan, Henrik Kaessmann, Fátima Adrio, Diego Robledo, Antón Barreiro-Iglesias, Eva Candal

Get full text

Hypoxia-inducible factor 1α is required to establish the larval glycolytic program in Drosophila melanogaster by Yasaman Heidarian, Tess D. Fasteen, Liam Mungcal, Kasun Buddika, Nader H. Mahmoudzadeh, Travis Nemkov, Angelo D'Alessandro, Jason M. Tennessen

“…The resulting mutant strains were analyzed using a combination of metabolomics and RNAseq for defects in carbohydrate metabolism. …”
Get full text

Síndrome de Sheehan: marcador de subdesarrollo by Alfredo Jácome Roca

“…El diagnóstico a menudo se hace tardíamente y los pacientes tienen deficiencia hormonal sintomática, por lo que se les debe dar terapia de suplencia, con el fin de mejorar la calidad de vida y evitar un potencial riesgo de muerte. …”
Get full text

Primary Schools’ Determinants of Pupils Academic Performance in Primary Leaving Examinations in Bubaare Sub-County Uganda. by Busingye, Annet

“…Key challenges included parents neglecting school activities, delaying payment of school fees and charges, failing to assist with academic assignments, and not attending school meetings, which disrupted school programs and strained parent-school communication. Children from disadvantaged families often lacked essential learning materials such as school fees and scholastic supplies, leading to frequent absenteeism or missing examinations. …”
Get full text

Systematic Review and Meta-Analysis on Human African Trypanocide Resistance by Keneth Iceland, Kasozi, Ewan Thomas, MacLeod, Susan Christina, Welburn

“…Conclusion: The emergence of drug resistance across the spectrum of trypanocidal agents that are used to treat HAT is a major threat to the global WHO target to eliminate HAT by 2030. T. brucei strains were largely resistant to diamidines and the use of high trypanocide concentrations in clinical studies have proved fatal in humans. …”
Get full text

Epidemiology of Trypanosomiasis in Wildlife—Implications for Humans at the Wildlife Interface in Africa by Keneth Iceland, Kasozi, Zirintunda, Gerald, Ssempijja, Fred, Buyinza, Bridget, Alzahrani, Khalid J., Matama, Kevin, Nakimbugwe, Helen N., Alkazmi, Luay, Onanyang, David, Bogere, Paul, Ochieng, Juma John, Islam, Saher, Matovu, Wycliff, Nalumenya, David Paul, Batiha, Gaber El-Saber, Osuwat, Lawrence Obado, Abdelhamid, Mahmoud, Shen, Tianren, Omadang, Leonard, Welburn, Susan Christina

“…African animal trypanosomiasis (AAT) affects both livestock and wildlife carrying a significant risk of spillover and cross-transmission of species and strains between populations. Increased human activity together with pressure on land resources is increasing wildlife–livestock–human infections. …”
Get full text

Development of an innovative intravaginal model of probiotic inoculation in dairy ovine flocks: positive effects on the vaginal microbiota, vaginitis and fertility by M. Toquet, J. Gomis, E. Jiménez-Trigos, E. Bataller, M. Barba, A. Sánchez, P. González-Torres, Á. Gómez-Martín

“…In vitro studies have reported the antimicrobial effect of an inoculum (L2) made from commercial probiotic strains of Lactobacillus spp. (Lactobacillus (L.) crispatus, L. brevis and L. gasseri) against some ruminants’ pathogens. …”
Get full text

Epidemiology and Resistance Profiles of Bacteria Isolated From Blood Samples in Septic Patients at Emergency Department Admission: A 6-Year Single Centre Retrospective Analysis Fro... by Valeria Cento, Sara Carloni, Riccardo Sarti, Linda Bussini, Zian Asif, Paola Morelli, Francesco De Fazio, Federica Maria Tordato, Maddalena Casana, Debora Mondatore, Antonio Desai, Elena Generali, Nicola Pugliese, Elena Costantini, Massimo Vanoni, Maurizio Cecconi, Stefano Aliberti, Giorgio Da Rin, Erminia Casari, Michele Bartoletti, Antonio Voza

“…Results: Antibiotic-susceptible Escherichia coli (29.5%) was the most common isolate, including extended-spectrum beta-lactamase (ESBL)-producing strains (11.3%), followed by methicillin-susceptible Staphylococcus aureus (MSSA, 8.4%). …”
Get full text

Advancing treatment choices: CDK4/6 inhibitor switching in HR+/HER2- metastatic breast cancer by Paola Zagami, Angela Esposito, Beatrice Taurelli Salimbeni, Pier Paolo Maria Berton Giachetti, Roberta Scafetta, Matteo Lambertini, Massimo Di Maio, Giuseppe Curigliano, Carmen Criscitiello, Saverio Cinieri

“…Purpose: CDK4/6 inhibitors (CDK4/6i) use has revolutionized the treatment of hormone receptor-positive/human epidermal growth factor receptor 2 negative (HR+/HER2-) metastatic breast cancer. …”
Get full text

Integrated analysis of biochemical, transcriptomic, and metabolomic response mechanisms in Ussuri catfish (Pseudobagrus ussuriensis) under acute heat stress by Qing Liu, Yang Cao, Ruyi Hu, Libo Gu, Lirong Yang, Yu Liu, Weiwei Wang, Liang Xiao, Bugao Li

“…These findings provide valuable insights into the defense mechanisms of fish under high-temperature stress and lay a theoretical foundation for breeding heat-resistant P. ussuriensis strains, as well as improving sustainable aquaculture management.…”
Get full text

Distinct mechanisms of electroacupuncture and manual acupuncture in modulating hypothalamic GnRH–tanycyte unit function of polycystic ovary syndrome by Yu Wang, Yicong Wang, Yuning Chen, Wenhan Lu, Xiaoyu Tong, Jiajia Li, Wenhao Gao, Rui Huang, Wei Hu, Yi Feng

“…Gonadotropin-releasing hormone (GnRH) neurons are pivotal in regulating hypothalamic endocrine function, whereas tanycyte, a specialized glial cell type, potentially contribute to this process. …”
Get full text

Eucalyptus grandis WRKY genes provide insight into the role of arbuscular mycorrhizal symbiosis in defense against Ralstonia solanacearum by Jianlang Zhang, Xinzhu Yang, Chunyu Huo, Xinyi Fan, Qiutong Liu, Zhihong Liu, Yu Su, Zujing Chen, Zujing Chen

“…The promoter regions of 50% of members of each subfamily contain plant hormone-related cis-elements associated with defense responses, such as ABREs, TGACG motifs, and CGTCA motifs. …”
Get full text