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1621
Novel gene manipulation approaches to unlock the existing bottlenecks of CAR-NK cell therapy
Published 2025-02-01“…As a potential alternative, CAR-NK cell therapy can overcome most of the limitations of CAR-T cell therapy and provide an off-the-shelf, safer, and more affordable product. Although published results from preclinical and clinical studies with CAR-NK cells are promising, several bottlenecks must be unlocked to maximize the effectiveness of CAR-NK cell therapy. …”
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1622
Dzieci z rodzin zastępczych w szkole. Raport o współpracy rodziców zastępczych z personelem szkoły
Published 2018-12-01“…Also, in their history of life they often experienced abuse and/or neglect, which may influence their later achievements (Kolankiewicz 2009; Bartnikowska, Ćwirynkało 2016). …”
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1623
Acute Intestinal Obstruction in Meckel’s Diverticulum
Published 2020-04-01“…A 9-year-old girl with abdominal pain and vomiting having appeared several hours before hospitalization was admitted to a paediatric surgical department. A few hours later, the child was operated. In the course of surgery, a strangulated intestinal obstruction was found on the mesodiverticular ligament connecting Meckel’s diverticulum with the root of the small intestine mesentery. …”
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1624
FOUCAULT E O USO DA HISTÓRIA Considerações introdutórias
Published 2014-04-01“…Através do qual, analisa as mudanças dos métodos punitivos, desde os castigos corporais, técnicas corretivas ate as tecnologias coercitivas do comportamento, que possibilitaram a formação de um saber clinico sobre os condenados, um discurso e uma forma de poder. …”
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1625
Deep visual proteomics reveals DNA replication stress as a hallmark of signet ring cell carcinoma
Published 2025-02-01“…We employed Deep Visual Proteomics (DVP), which combines AI-directed cell segmentation and classification with laser microdissection and ultra-high sensitivity mass spectrometry, for cell-type-specific proteomic analysis of SRCC across the bladder, prostate, seminal vesicle, and a lymph node of a single patient. …”
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1626
John Paul II and Benedict XVI’s concern for the protection of the faithful against the most serious crimes, with particular emphasis on the sexual abuse of minors committed by cler...
Published 2024-06-01“…The problem of dealing justly and efficiently with the most serious crimes in the Church after the promulgation of the Code of Canon Law in 1983 became the concern of Cardinal Joseph Ratzinger, later Benedict XVI, and John Paul II. Their cooperation and the decisions of Benedict XVI, as a continuation of the path started, laid the foundations for the creation of a system of canonical criminal law capable of responding properly and effectively to the most serious crimes committed by the faithful in the Church. …”
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1627
Drivers influencing the adoption of cryptocurrency: a social network analysis approach
Published 2025-02-01“…Our analysis initially revealed 44 influential factors, which were later reduced to 25 factors, each exerting a different influence. …”
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1628
Homeostasis and metabolism of iron and other metal ions in neurodegenerative diseases
Published 2025-02-01“…In this review, the research history and milestone events of studying metal ions, including iron, manganese, copper, and zinc in neurodegenerative diseases such as Parkinson’s disease (PD), Alzheimer’s disease (AD), amyotrophic lateral sclerosis (ALS), and Huntington’s disease (HD), will be introduced. …”
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1629
Lo absoluto hegeliano como condición de posibilidad del pensamiento puro. libertad, autoconciencia y experiencia en Hegel
Published 2021-01-01“…Por eso lo absoluto y el saber de lo absoluto es lo mismo. El absoluto no es un ser trascendente sino que sólo existen en nosotros, en la autoconciencia intersubjetiva.…”
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1630
Classical Biological Control of Tropical Soda Apple with Gratiana boliviana
Published 2013-01-01“…., Florida in 1988, it later spread to Georgia, Alabama, Louisiana, Texas, Mississippi, Tennessee, North Carolina, and South Carolina. …”
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1631
REE-Nb MINERALIZATION IN TRACHYTES AND RHYOLITES OF THE KHULAM VOLCANO-PLUTONIC COMPLEX, NORTH CAUCASUS
Published 2021-12-01“…The fluorocarbonates and ilmenorutile formed later as a result of autometamorphism and low-temperature hydrothermal alteration of felsic rocks.…”
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1632
Management of Nasoalveolar Cyst by Transnasal Endoscopic Marsupialization
Published 2023-09-01“…In our experience, microdebrider assisted endoscopic transnasal marsupialisation is an easier, faster, safer, and equally efficacious technique to treat nasolabial cyst without any recurrence. …”
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1633
Gréckokatolícki mučeníci z obdobia neslobody 1939–1989
Published 2012-07-01“…Among the presented figures are the bearers of the title Righteous Among the Nations, award-winning in Israel for unconditional aid to Jews during World War II, as they were risking the loss of his life and lives of family members for saving the racially and religiously persecuted. Given later, the contribution is divided into two parts, the first presents the blessed martyrs, that those who died as martyrs and the second part is devoted to individuals who risked their lives while were exposed to the death for rescuing Jews.…”
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1634
Orally administered organophosphorus dimethoate mediated biochemical alterations in male and female experimental Rattus norvegicus (albino rats)
Published 2025-02-01“…This study provides a foundation for further research on the long-term effects of dimethoate and similar pesticides, promoting the development of safer alternatives.…”
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1635
A case of neuronal intranuclear inclusion disease (NIID) presenting with hydrocephalus-like clinical features: case report
Published 2025-02-01“…Over the past year, she noticed stiffening at the root of her tongue, cognitive decline, and slower reaction times compared to her previous state. …”
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1636
Mixture of Bacillus Amyloliquefaciens and Bacillus Pumilus Modulates Community Structures of Rice Rhizosphere Soil to Suppress Rice Seedling Blight
Published 2025-01-01“…Analysis of 16S and internal transcribed spacer rRNA gene sequencing data revealed that the mixture of the T40 and T208 strains exhibited the lowest average clustering coefficients, which were negatively correlated with the biomass of F. oxysporum-inoculated rice seedlings. …”
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1637
Evaluation and testing of polymethylmetacrylic (PMMA) bone cements with admixed Amphotericin B
Published 2025-02-01“…Abstract Background Amphotericin is admixed to Polymethylmethacrylic (PMMA) spacers for fungal periprosthetic joint infections (PJI) during two-stage exchanges. …”
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1638
An Automated Clinical Laboratory Decision Support System for Test Utilization, Medical Necessity Verification, and Payment Processing
Published 2025-02-01“…These inappropriate test orders not only lead to slower or incorrect diagnoses for patients but also add a significant financial burden. …”
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1639
The chromosome-level genome provides insights into the adaptive evolution of the visual system in Oratosquilla oratoria
Published 2025-02-01“…In addition, the evolutionary rate of O. oratoria was slightly faster than that of Dendrobranchiata and slower than that of Pleocyemata. Interestingly, we observed the significant expansion of middle-wavelength-sensitive (MWS) opsins in the O. oratoria genome by tandem duplication, partially contributing to their unique visual capabilities. …”
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1640
Optimizing fast charging protocols for lithium-ion batteries using reinforcement learning: Balancing speed, efficiency, and longevity
Published 2025-03-01“…The findings show that quicker charging profiles speed up deterioration, raise temperature, and hasten the drop of SoH even though they shorten charging times. Slower profiles, on the other hand, improve long-term battery health and efficiency by controlling temperature and minimizing deterioration, even though they require longer charging times.The RL-based approach balances quick charging with battery preservation by implementing a reward system that penalizes dangerous conditions like high voltage or temperature in order to lessen these trade-offs. …”
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