Slope Aspect Differentiation of Pisha Sandstone Slide Erosion and Its Response to Meteorological Factors by REN Yanan, LI Long, ZHANG Shangxuan, ZHANG Yu, ZHOU Xingchen

“…[Methods] Using the gully slope system in Inner Mongolia as the study area, field monitoring and three-dimensional laser scanning technology were employed to analyze the spatial and temporal changes in micro-topography and erosion characteristics of the erosion interface under different slope aspects. …”
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Incidence of type 2 diabetes and metabolic syndrome by Occupation – 10-Year follow-up of the Gutenberg Health Study by Juliane Bauer, Janice Hegewald, Karin Rossnagel, Sylvia Jankowiak, Michaela Prigge, Julian Chalabi, Matthias Nübling, Alice Freiberg, Merle Riechmann-Wolf, Pavel Dietz, Philipp S. Wild, Thomas Koeck, Manfred E. Beutel, Norbert Pfeiffer, Karl J. Lackner, Thomas Münzel, Konstantin Strauch, Philipp Lurz, Oliver Tüscher, Julia Weinmann-Menke, Stavros Konstantinides, Andreas Seidler

“…Methods Employees of the population-based Gutenberg-Health-Study (GHS) were examined at baseline (2007–2012) and 10 years later. We calculated age- and sex-standardised incidence rates and standardised incidence ratios (SIR) with a 95% confidence interval (CI) for occupations, job complexity levels, and supervisory and managerial positions. 5954 persons at risk for type 2 diabetes and 5103 at risk for metabolic syndrome were observed. …”
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Loss of MEF2C function by enhancer mutation leads to neuronal mitochondria dysfunction and motor deficits in mice by Ali Yousefian-Jazi, Suhyun Kim, Jiyeon Chu, Seung-Hye Choi, Phuong Thi Thanh Nguyen, Uiyeol Park, Min-gyeong Kim, Hongik Hwang, Kyungeun Lee, Yeyun Kim, Seung Jae Hyeon, Hyewhon Rhim, Hannah L. Ryu, Grewo Lim, Thor D. Stein, Kayeong Lim, Hoon Ryu, Junghee Lee

“…Abstract Background Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disorder characterized by the loss of both upper and lower motor neurons, leading to progressive paralysis. …”
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An optimized data analytics pipeline for improving healthcare diagnosis using ensemble learning by Lomat Haider Chowdhury, Shaira Tabassum, Swakkhar Shatabda, Ashir Ahmed

“…The paper systematically evaluates different preprocessing methods for missing value imputation, outliers detection, and data balancing and offers a comprehensive preprocessing framework. Later, five state-of-the-art ensemble models for healthcare diagnosis were implemented along with a proposed ensemble machine learning model, KNN-XGBoost-SVM-Random Forest (KNN-X-SVM-R). …”
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Neuroprotective role of epigallocatechin-3-gallate, albeginin and melanoxetin in alzheimer's disease by Arif Malik, Mehreen Hassan, Sulayman Waquar, Muhammad Wasim, Anam Naz, Faryal M. Awan, Muhammad T. Khan, Ali I. Khawaja, Sumera Zaib, Jamshed Iqbal, Ayesha Zahid, Marvi Marvi, Javeid Iqbal, Heng Wang, Dong-Qing Wei

“…Phytochemicals are considered safer alternatives and have shown significant efficacy in inhibiting cholinesterase, scavenging free radicals, inhibiting amyloid-β neurotoxicity, reducing inflammation, and interacting with neurotransmitters, thereby slowing down the progression of AD. …”
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Vaginal bleeding during pregnancy: a retrospective cohort study assessing maternal and perinatal outcomes by Maroun Matar, Georges Yared, Christopher Massaad, Kariman Ghazal

“…An increased risk for NICU admissions and conditions such as respiratory distress in neonates was found, alongside a significant association with post-delivery bleeding and premature labor in the later trimesters. Conclusions Vaginal bleeding during pregnancy was not found to be significantly associated with maternal age, parity, abortion history, or total pregnancies. …”
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How Do Diabetes Models Measure Up? A Review of Diabetes Economic Models and ADA Guidelines by Lindsay Govan, Olivia Wu, Robert Lindsay, Andrew Briggs

“…Most models were developed in the United States, United Kingdom, Europe or Canada. Later models use data or methods from earlier models for development or validation. …”
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The Role of Aspartate Aminotransferase/Platelet Ratio Index Score in Predicting Intrahepatic Cholestasis of Pregnancy and its Relationship with Total Bile Acid Level: A Case-Contro... by Merve Demir, Emre Sertel

“… OBJECTIVES: The aim of this study is to examine the value of the first-trimester aspartate aminotransferase to platelet ratio index (APRI) score in predicting intrahepatic cholestasis of pregnancy (ICP) occurring later in pregnancy. Another aim of the study is to determine the relationship between APRI scores and total bile acid (TBA) levels in pregnant women with ICP. …”
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We Are on the Verge of Breakthrough Cures for Type 1 Diabetes, but Who Are the 2 Million Americans Who Have It? by Rebecca Smith, Samara Eisenberg, Aaron Turner-Phifer, Jacqueline LeGrand, Sarah Pincus, Yousra Omer, Fei Wang, Bruce Pyenson

“…**Discussion:** Our results showed important differences in T1DM prevalence and incidence across regions, payers, and ethnic groups. This suggests studies based on more geographically concentrated data may miss important variation in prevalence and incidence across regions. …”
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Cost-effectiveness Analysis of Ribociclib plus Letrozole versus Palbociclib plus Letrozole in the United Kingdom by Gaurav Suri, David Chandiwana, Adam Lee, Rohit Mistry

“…**Objective:** To evaluate the cost-effectiveness of ribociclib plus letrozole versus palbociclib plus letrozole in post-menopausal women with hormone receptor positive (HR+) and human epidermal growth receptor 2 negative (HER2-) advanced breast cancer from a UK payer perspective. **Methods:** A cohort-based partitioned survival model was developed to evaluate the cost-effectiveness of ribociclib plus letrozole versus palbociclib plus letrozole in post-menopausal women with HR+/HER2- advanced breast cancer over a lifetime horizon. …”
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Assessment of vegetation in Murchison falls national park five years after the completion of oil and gas exploration by Hindrah Akisiimire, William Tinzaara, Keneth Tumwebaze, Charles K.Twesigye

“…The same procedure was conducted at a frequency of wet (4th-30th April 2019) and dry (1st-30th June 2019) seasons. The counted data was later transformed and analyzed using t-statistical tests and chi- square tests in SPSS version 20 software. …”
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Community perceptions of community health worker effectiveness: Contributions to health behaviour change in an urban health district in South Africa by L S Thomas, Y Pillay, E Buch

“…The community members highly rated care for chronic conditions (82%), indicated that children were healthier (41%) and had safer pregnancies (6%). Conclusion. As important stakeholders in CHW programmes, exploring community acceptance, appreciation and support is critical in understanding the drivers of programme performance. …”
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The kinetics of maternal and self-developed Streptococcus suis-specific antibodies by Sandra Vreman, Rutger Jansen, Mikael Bastian, Patricia Beckers, Miriam van Riet, Helmi Fijten, Jan Fledderus, Astrid de Greeff, Hélène Winkelman, Norbert Stockhofe-Zurwieden, Lluís Fabà, Henk J. Wisselink, Manouk Vrieling

“…Colostrum intake, birth weight and 24-h weight gain after birth were important parameters that were positively associated with S. suis antibody levels in piglets after birth but also affected these antibody levels at a later age. All the piglet tonsils were colonized with S. suis serotype 9 before weaning, while the prevalence of serotype 2 increased after weaning. …”
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Socioeconomic factors and sex effects of postpartum maternal depression on offspring internalizing symptoms: a systematic review and meta-analysis by Yang Geng, Wenlan Liu, Zhiying Yu, Hui Zhang, Yun Li, Weihua Zhao

“…Therefore, the significant sex effects of postpartum maternal depression are more likely due to complex interactions between maternal depression and the intrauterine and postpartum environments that shape offspring sex-difference trajectories, with consequences occurring for later internalizing symptoms in adolescence. Trial registration PROSPERO, CRD42022301445.…”
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Transcriptome Analysis of Effect of Cordyceps militaris Aqueous Extract in Human Gastric Cancer Cell BGC-823 on Different RCD Pathways by Mingqi CUI, Kaiwen YU, Yang SONG, Fangxu XU, Shenghou WANG, Ze WANG

“…Transcriptome analysis revealed significant differentially expressed genes (DEGs) and their Kyoto Encyclopedia of Genes and Genomes (KEGG) enrichment, resulting in the identification of 10 hub genes involved in the apoptosis, autophagy, necroptosis, and ferroptosis signaling pathways. Laser confocal microscopy, flow cytometry, and quantitative real time polymerase chain reaction (qRT-PCR) were employed to further validate the induction of apoptosis in gastric cancer cells by the XG aqueous extract. …”
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Men's more frequent predisposing factors in infectious endocarditis facilitate improvement of outcomes by shortening of diagnostic delay by S. Andreß, K. Reischmann, S. Markovic, F. Rohlmann, B. Hay, W. Rottbauer, D. Buckert, S. d'Almeida

“…Men diagnosed within 3.5 days had a mortality rate of 13.5% compared to 31.8% for those diagnosed later (p = 0.028).ConclusionMen with suspected IE are younger, have more predisposing factors and experience a more complicated course of disease, while benefiting from early diagnosis. …”
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Efficacy of drugs most commonly prescribed at functional gastrointestinal diseases (functional dyspepsia syndrome and irritable bowel syndrome) observational study results by V. T. Ivashkin, Ye. A. Poluektova, D. V. Reykhart, O. S. Shifrin, A. G. Beniashvili, O. S. Lyashenko, A. V. Belostotsky

“…During the first visit to the doctor patient was proposed to complete «7×7» questionnaire for baseline assessment of presence and severity of symptoms typical for FD and IBS. Later all patients underwent a set of laboratory and instrumental tests required according to «Guidelines on diagnostics and treatment of the irritable bowel syndrome in adults» of the Russian gastroenterological association and Russian Association of coloproctology and to «Clinical guidelines on diagnostics and treatment of the functional dyspepsia» of the Russian gastroenterological association. …”
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Savings and Credit Co-Operative Societies (Saccos) and Poverty Reduction in Kabale District. by Anita, Kamagara

“…Findings revealed that SACCOs helped to build financial and business management capacity of rural households hence improving their asset holdings, SACCOs mitigate income fluctuations, minimizes unexpected expenditures and emergencies which builds a small asset base over time among rural households, they enhance savings and investment which later promotes greater asset accumulation. The study concluded that SACCOs should inform the shareholders of the services available and should sensitize them on the better ways how to utilize the products in order to alleviate poverty in the community. …”
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Anti-obesity effects of Erythrina abyssinica stem bark extract in flies exposed to a high fat diet by Oscar Hilary, Asiimwe, Eddie, Wampande, John, Rubaihayo, Keneth Iceland, Kasozi, Hellen, Wambui Kinyi

“…Though the standard drug fenofibrate had the highest fat accumulation reduction potential, the extract at 7.5 g/ml was much safer in reducing fat accumulation in obese male D. melanogaster than other concentration used. …”
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Microscale bone interlocking enhances osseointegration strength on the rough surface of 3D-printed titanium implants: experimental and finite element analysis by Tianyu Shu, Haoyu Shi, Meng Li, Yu-Chia Lin, Ang Li, Dandan Pei

“…Methods Experimental 3D-printed titanium implants were fabricated via selective laser melting (SLM), and conventional sandblasted and acid-etched titanium implants (CNC-SLA) served as the control group. …”
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