Altered Respiratory Physiology in Obesity by Krishnan Parameswaran, David C Todd, Mark Soth

“…Conventional respiratory function tests are only mildly affected by obesity except in extreme cases. …”
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Single-cell analyses of intestinal epithelium reveal the dysregulation of gut immune microenvironment in systemic lupus erythematosus by Qiaolin Wang, Yutong Wu, Lianlian Ouyang, Xiaoli Min, Meiling Zheng, Lingyu Gao, Xiaoyun Chen, Zhi Hu, Shuang Yang, Wenjuan Jiang, Sujie Jia, Qianjin Lu, Ming Zhao

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Immediate Changes in the Elasticity of Tissue and the Pain Pressure Threshold in Cesarean Scar Tissue After a Vacuum Intervention: An Open Clinical Trial by Ana González-Muñoz, Santiago Navarro-Ledesma

“…Addressing these concerns is essential to improving patient comfort and functional outcomes. This study aimed to assess the immediate effects of vacuum therapy on skin elasticity and pain sensitivity in C-section scar tissue. …”
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Implications of thermal stratification and radiative heat flux in blood-based ternary and dihybrid nanomaterial flow through a stretchable cylinder by Muzher Saleem, Ghada A. Khouqeer, Fazal Haq, Naglaa AbdelAll, Arshad Hussain, Mohammed Sallah

“…A reduction of 4 % in the skin friction coefficient of THNF compared to HNF is noticed. …”
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CoQ deficiency causes disruption of mitochondrial sulfide oxidation, a new pathomechanism associated with this syndrome by Marta Luna‐Sánchez, Agustín Hidalgo‐Gutiérrez, Tatjana M Hildebrandt, Julio Chaves‐Serrano, Eliana Barriocanal‐Casado, Ángela Santos‐Fandila, Miguel Romero, Ramy KA Sayed, Juan Duarte, Holger Prokisch, Markus Schuelke, Felix Distelmaier, Germaine Escames, Darío Acuña‐Castroviejo, Luis C López

“…Therefore, SQR may be affected by CoQ deficiency. Using human skin fibroblasts and two mouse models with primary CoQ deficiency, we demonstrate that severe CoQ deficiency causes a reduction in SQR levels and activity, which leads to an alteration of mitochondrial sulfide metabolism. …”
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Therapeutic Effects of Topical Traditional Chinese Medicine on Upper Extremity Fractures by Lin WY, Lu CA, Chang CW, Yeh YC

“…Both WYGJJW and RYJHS groups showed statistical significance in swelling reduction [WYGJJW: 0.95 cm (IQR: 0.9– 1.9); RYJHS: 1.05 cm (0.5– 5.35)], pain relief [WYGJJW: 2 points (0.88– 4.5); RYJHS: 2 (1– 2.25)], and functional improvement [WYGJJW: 7.96 points (2.95– 16.48); RYJHS: 4.39 (2.27– 14.72)]. …”
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Macrodactyly: report of eight cases of a rare anomaly by N Kostakoglu, A Kayikcioglu, T Safak, G Ozcan, A Kecik, G Gursu

“…Six patients underwent resection of the proximal phalanges together with bulk reduction of the soft tissue mass. Only soft tissue reduction was performed in the remaining two patients. …”
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Considerations for Use of Ultrashort Wave Therapy in Management of COVID-19 Patients by Pengming YU, Alice Y M JONES, E-Liisa LAAKSO

“…Further, in any application of electrotherapy modality to a patient, procedures involving assessment of reliability of machine output and normal skin sensation of the patient must be ascertained. …”
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Psychological Health in the Management of Patients with Psoriatic Arthritis: An Intricate Relationship by Ennio Lubrano, Pasquale Ambrosino, Fabio Massimo Perrotta

“…The disease can lead to a range of emotional difficulties, including anxiety, depression, and diminished self-esteem. The visible skin manifestations of psoriasis, coupled with the persistent pain and functional limitations of arthritis, can significantly affect body image and self-worth. …”
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RADIATION-INDUCED TOXICITY IN BREAST CANCER PATIENTS TREATED WITH TRASTUZUMAB-BASED CHEMOTHERAPY by R. Yu. Karabut, A. V. Vazhenin, E. Y. Mozerova, M. M. Sarycheva, A. A. Lozhkov, A. Yu. Maksimovskaya, D. M. Timokhina

“…The aim of the study was to determine and analyze the most significant risk factors for developing cardiac, pulmonary and skin toxicities among patients who received concurrent radiation therapy and chemotherapy with trastuzumab.Material and methods. …”
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Everolimus long-term use in patients with tuberous sclerosis complex: Four-year update of the EXIST-2 study. by John J Bissler, J Chris Kingswood, Elzbieta Radzikowska, Bernard A Zonnenberg, Elena Belousova, Michael D Frost, Matthias Sauter, Susanne Brakemeier, Petrus J de Vries, Noah Berkowitz, Maurizio Voi, Severine Peyrard, Klemens Budde

“…Almost all patients (97%) experienced reduction in renal lesion volumes at some point during the study period. …”
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Blunted cardiovascular responses in individuals with type 2 diabetes and hypertension during cold and heat exposure by Mojdeh Rafieian, Erlend Hoftun Farbu, Anje Christina Höper, Anje Christina Höper, Rasmus Valtonen, Rasmus Valtonen, Henna Hyrkäs-Palmu, Juha Perkiömäki, Juha Perkiömäki, Craig Crandall, Jouni J. K. Jaakkola, Jouni J. K. Jaakkola, Tiina Maria Ikäheimo, Tiina Maria Ikäheimo

“…IntroductionThe effect of type 2 diabetes (T2D) on indices of cardiovascular function during exposure to cold or hot environmental temperatures is not well known. …”
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Long-term follow-up of modified shunt-restricted instep arterialized venous flap for reconstruction of hand defects by Wei Chen, Yang Jian, Maolin Cheng, Runxue Guan, Wenyu An, Chenglan Yang, Jian Zhou, Shujun Li, Shusen Chang, Chengliang Deng, Chengliang Deng, Kaiyu Nie, Kaiyu Nie, Zairong Wei, Zairong Wei, Zairong Wei, Zairong Wei

“…The color and texture of the flap were close to healthy skin, and joint function was satisfactorily recovered. …”
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Therapeutic Mechanism of Kynurenine, a Metabolite of Probiotics, on Atopic Dermatitis in Mice by Yixuan Li, Mingxin Li, Qingyu Ren, Chunqing Ai, Shugang Li, Huan Li, Shouhao Zhao, Donglin Sui, Xiaomeng Ren

“…Further research indicates that KYN’s therapeutic effects on AD are primarily manifested in the reduction of secretory immunoglobulin A (sIgA), immunoglobulin E (IgE), interleukin-4 (IL-4), IL-5, IL-13, and thymic stromal lymphopoietin (TSLP) levels in mice, while also repairing the intestinal barrier function of AD mice. …”
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Two in one: Double free flap from a single free fibula osteocutaneous unit by Prabha S Yadav, Vinay K Shankhdhar, Jaiswal Dushyant, Sakthipalan Selva SeethaRaman, Gujjalanvar Rajendra

“…But in our institute, we have managed two such cases of extensive COMD with a single FFOCF unit - fibula bone with a skin paddle for inner lining and a perforator-based skin paddle from the proximal part of the FFOCF unit, anastomosed separately for outer cover. …”
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Effects of mindfulness meditation on human impulsivity: a systematic review and meta-analysis by Eric W. Tsang, Junling Gao, Chi Ngai Lo, Nicholas T. Trapp, Aaron D. Boes, Hinhung Sik

“…In addition, MM modulated autonomic nervous system activity by decreasing the levels of salivary and blood cortisol, food-craving-related salivation, galvanic skin response, and salivary immunoglobulin A (Cohen’s d = −0.48, 95% CI [−0.79, −0.01]). …”
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Dynamic Digital Radiography in Ehlers–Danlos Syndrome: Visualizing Diaphragm Motility Impairment and Its Influence on Clinical Management by Elisa Calabrò, Maurizio Cè, Francesca Lucrezia Rabaiotti, Laura Macrì, Michaela Cellina

“…Suspecting diaphragm dysfunction, the patient underwent Dynamic Digital Radiography (DDR) that confirmed a reduction in left diaphragm motility, indicative of impaired diaphragm function. …”
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Unraveling the interplay between mesenchymal stem cells, gut microbiota, and systemic sclerosis: therapeutic implications by Lili Zhang, Hui Wang, Lu Zhao, Jin Zhang, Wenchang Sun, Jinjin Chu, Haobin Zhao, Chunjuan Yang, Shushan Yan, Xiaohua Chen, Donghua Xu

“…The administration of MSCs has been shown to regulate the disrupted metabolic pathways in SSc mice, thus restoring the normal function of the gut microbiota. This study provides valuable insights into the specific gut microbiota and metabolic pathways involved in the efficacy of MSC treatment, thereby proposing a novel therapeutic strategy for SSc.IMPORTANCEHuman umbilical cord-derived mesenchymal stem cells (HUC‑MSCs) demonstrate efficacy in alleviating skin thickening and collagen deposition in systemic sclerosis (SSc) mice, which also regulate the gut microbiota composition and function. …”
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Study on the therapeutic effects of Qinghuang ointment in a mouse model of imiquimod-induced psoriasis and its underlying mechanisms by LIU Dan, GONG Canyi, XU Jing, WEN Si, WU Zhaoji, HE Jiao, XIA Bijun

“…[Conclusions] Qinghuang ointment has a good therapeutic effect on psoriasis in mice, and its mechanism may be related to improving skin barrier function, modulating immune responses, and inhibiting Th1/Th17 cell-mediated inflammatory response.…”
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RITUXIMAB TREATMENT FOR INTERSTITIAL LUNG INJURY IN SCLERODERMA SYSTEMATICA by Lidia Petrovna Ananieva, O V Desinova, O A Koneva, M N Starovoitova, N N Yutkina, A V Volkov, O B Ovsyannikova, A P Aleksankin, E N Aleksandrova, A A Novikov, E L Nasonov

“…There was a significant increase in mean FVC one year after the first administration of RTM and a reduction in the total activity of the disease, including skin syndrome. …”
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