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GsMTx-4 venom toxin antagonizes biophysical modulation of metastatic traits in human osteosarcoma cells
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OLIG2 mediates a rare targetable stem cell fate transition in sonic hedgehog medulloblastoma
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Pathogenic PDE12 variants impair mitochondrial RNA processing causing neonatal mitochondrial disease
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The Effects of Hyperacute Serum on the Elements of the Human Subchondral Bone Marrow Niche
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Frameworks for the design and reporting of anaesthesia interventions in perioperative clinical trials
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Preclinical study and parallel phase II trial evaluating antisense STAT3 oligonucleotide and checkpoint blockade for advanced pancreatic, non-small cell lung cancer and mismatch re...
Published 2024-07-01“…In vitro experiments evaluated STAT3 inhibition in pancreatic stellate cells (PSCs) and myeloid-derived suppressor cells (MDSCs).A phase II trial employing a Simon II stage design tested the clinical efficacy of danvatirsen and durvalumab in non-small cell lung cancer (NSCLC), PDAC and mismatch repair-deficient colorectal cancer (MRD CRC). …”
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