Candidate SNP markers of social dominance, which may affect the affinity of the TATAbinding protein for human gene promoters by I. V. Chadaeva, D. A. Rasskazov, E. B. Sharypova, L. K. Savinkova, P. M. Ponomarenko, M. P. Ponomarenko

“…The proposed hypothesis, the candidate SNP markers predicted and the observed regularities of effects of natural selection for the human genome are discussed in comparison with published data: whether they can have any relation to social dominance in human. …”
Get full text

Dose-response associations of device-measured sleep regularity and duration with incident dementia in 82391 UK adults by Wenxin Bian, Raaj K. Biswas, Matthew N. Ahmadi, Yu Sun Bin, Svetlana Postnova, Andrew J. K. Phillips, Nicholas A. Koemel, Jean-Philippe Chaput, Shantha M. W. Rajaratnam, Peter A. Cistulli, Emmanuel Stamatakis

“…To evaluate the associations of device-measured sleep duration and regularity with incident dementia and explore whether sleep regularity moderates the association of sleep duration with dementia. …”
Get full text

Automated and code-free development of a risk calculator using ChatGPT-4 for predicting diabetic retinopathy and macular edema without retinal imaging by Eun Young Choi, Joon Yul Choi, Tae Keun Yoo

“…In many communities, access to ophthalmologists and retinal imaging equipment is limited, making screening for diabetic retinal complications difficult in primary health care centers. We investigated whether ChatGPT-4, an advanced large-language-model chatbot, can develop risk calculators for DR and DME using health check-up tabular data without the need for retinal imaging or coding experience. …”
Get full text

Continuous theta-burst stimulation demonstrates language-network-specific causal effects on syntactic processing by Chenyang Gao, Junjie Wu, Yao Cheng, Yuming Ke, Xingfang Qu, Mingchuan Yang, Gesa Hartwigsen, Luyao Chen

“…In particular, it remains to be demonstrated whether the language network plays a specific causal role in comparatively challenging syntactic processes, separable from the interaction between IFG and other general cognitive regions (i.e., “IFG + SPL” in the present study). …”
Get full text

Serum Levels of Epithelial-Derived Cytokines as Interleukin-25 and Thymic Stromal Lymphopoietin after a Single Dose of Mepolizumab in Patients with Severe Non-Allergic Eosinophilic... by Virginija Kalinauskaite-Zukauske, Andrius Januskevicius, Ieva Janulaityte, Skaidrius Miliauskas, Kestutis Malakauskas

“…However, there is a lack of data on whether reduced airway eosinophilic inflammation can affect the production of epithelial-derived mediators, such as interleukin-25 (IL-25) and thymic stromal lymphopoietin (TSLP). …”
Get full text

Community perspectives regarding brain-computer interfaces: A cross-sectional study of community-dwelling adults in the UK. by Austen El-Osta, Mahmoud Al Ammouri, Shujhat Khan, Sami Altalib, Manisha Karki, Eva Riboli-Sasco, Azeem Majeed

“…The study also explored whether demographic factors were related to beliefs about BCIs increasing inequalities, support for strict regulations, and perceptions of appropriate fields for BCI design, testing and utilization in healthcare.…”
Get full text

Global comparison of the economic costs of coronary heart disease: a systematic review and meta-analysis by Lan Gao, Susan Brumby, Crystal Man Ying Lee, George Mnatzaganian, Suzanne Robinson, Helen Brown, Rachel Huxley, Anna Peeters, Dan Xu, James Boyd, Sean Randall, Adrienne O’Neil, Sangita Shakya, Sarah Gauci, Anita Shrestha, James Lucas

“…We conducted a systematic review with meta-analysis to examine the costs of CHD treatment by region and CHD subtypes, examine whether there are cost difference by sex, and examine costing methodologies.Design We conducted a systematic review and meta-analysis of non-randomised studies.Data sources We searched Medline, Embase, CINAHL, EconLit and Google Scholar from 1 January 2000 to February 2023.Eligibility criteria for selecting studies We included observational studies reporting economic costs of CHD treatment and outcomes for adults that were published in English.Data extraction and synthesis Data extraction and quality assessment were independently undertaken by two reviewers. …”
Get full text

The relationship between physical activity and career decision-making self-efficacy in Chinese college students: the mediating roles of self-control and social anxiety by Yuan Fang, Tingting Xu, Maosheng Ye, Changquan Li

“…A total of 5,000 samples were randomly drawn for the purpose of validating the research hypotheses, with the determination being based on whether the 95% confidence interval encompassed the value of 0.Results(1) Physical activity was found to positively predict career decision-making self-efficacy, as evidenced by (Estimate = 0.590, p < 0.001). (2) Self-control was demonstrated to play a mediating role in the connection between physical activity and career decision-making self-efficacy, with the effect indicated by (Estimate = 0.075, 95%CI(0.042, 0.113)]. (3) Social anxiety was likewise shown to assume a mediating role within the relationship between physical activity and career decision-making self-efficacy, as manifested by [Estimate = 0.009, 95%CI(0.002, 0.020)]. (4) A chain mediating effect was observed between physical activity and career decision-making self-efficacy for the combination of self-control and social anxiety, with [Estimate = 0.032, 95%CI(0.008, 0.057)].ConclusionThese findings provided significant theoretical support for physical activity as an effective means to enhance university students' career decision-making self-efficacy and offered references for designing sports activity programs. …”
Get full text

Deteksi Gulma Berdasarkan Warna HSV dan Fitur Bentuk Menggunakan Jaringan Syaraf Tiruan by Hurriyatul Fitriyah, Rizal Maulana

“…Those features were fed into a learning algorithm, Artificial Neural Network (ANN), to classify whether it is the plant or the weed. The testing on the weed classification in a real outdoor environment showed 95.46% accuracy using a total of 149 detected plants (70% as training data, 15%  as validation data, and 15% as testing data). …”
Get full text

Personalized neuron-specific enolase level based on EEG pattern for prediction of poor outcome after cardiac arrest by Juliette Pelle, Estelle Pruvost-Robieux, Florence Dumas, Antonin Ginguay, Julien Charpentier, Clara Vigneron, Frédéric Pène, Jean Paul Mira, Alain Cariou, Sarah Benghanem

“…The objective was to determine whether the NSE threshold which predicts poor outcome varies according to EEG patterns and the effect of electrographic seizures on NSE level. …”
Get full text

Thrombolysis, time-to-treatment and in-hospital outcomes among young adults with ischaemic stroke in China: findings from a nationwide registry study in China by Yong-Jun Wang, Xin Yang, Qi Zhou, Hao Li, Xia Meng, Yong Jiang, Li-Ping Liu, Yi-long Wang, Hong-Qiu Gu, Zi-Xiao Li, Xing-Quan Zhao, Chun-Juan Wang, Chelsea Liu, Hai-yan Wang, Ying-Yu Jiang

“…Background and purpose We aimed to determine whether young adults (<50 years) with acute ischaemic stroke (AIS) are more likely to receive intravenous tissue plasminogen activator (IV tPA) and have shorter time to treatment than older patients with stroke.Methods We analysed data from the Chinese Stroke Center Alliance registry for patients with AIS hospitalised between August 2015 and July 2019. …”
Get full text

Corticosteroid use beyond 1-year post heart transplantation is associated with worse outcomes: A contemporary analysis of the ISHLT registry by Abhishek Jaiswal, MD, William L. Baker, Pharm.D, Ashwin Pillai, MD, Michelle Kittleson, MD, PhD, Balaphanidhar Mogga, MD, Zeina Jedeon, MD, Caroline Chen, David A. Baran, MD

“…Conclusions: Steroid use beyond 1year post heart transplant was associated with significantly lower survival, and worsened morbidity among adult recipients. Whether this observation indicates steroid use is a marker of higher risk or worsens prognosis warrants prospective investigation.…”
Get full text

Brief Report: Not Created Equal: Survival Differences by KRAS Mutation Subtype in NSCLC Treated With Immunotherapy by Lova Sun, MD, MSCE, Yunyun Zhou, PhD, Elizabeth A. Handorf, PhD, Hossein Borghaei, DO, Jessica Bauman, MD, Charu Aggarwal, MD

“…We used a nationwide observational database to investigate whether KRASm subtypes differ in their association with survival in metastatic NSCLC treated with immune checkpoint inhibitor (ICI)-based therapy, across programmed death-ligand 1 (PD-L1) levels. …”
Get full text

Effects of Electrical Stimulation on Activation of Mirror Neuron Network in Healthy Adults during Motor Execution and Imitation: An fNIRS Study by Yao Cui, Fang Cong, Fu-Biao Huang, Ming Zeng, Jun Wang

“…This study aims to reveal whether ES could impact cortical activation during ME and MI. …”
Get full text

Reusing of Organic Waste from Tubifex sp. Substrate in nature by D. Shafruddin, W. Efiyanti, . Widanarni

“… This study was conducted to determine whether organic waste from the substrate of Tubifex sp. can be used as inoculants to produce them through culture.   …”
Get full text

Relationship of monocyte to high-density lipoprotein ratio (MHR) and other inflammatory biomarkers with sarcopenia: a population-based study by Zhiwei Xue, Jian Cao, Jianhui Mou, Rui Wang, Peng Liu

“…Abstract Objectives In previous studies, several inflammatory biomarkers derived from complete blood cell counts (CBC), such as systemic immune inflammation index (SII), neutrophil-to-lymphocyte ratio (NLR), and non‑high‑density lipoprotein cholesterol to high‑density lipoprotein cholesterol ratio (NHHR) have been identified as predictors of sarcopenia. However, whether Monocyte to High-Density Lipoprotein Cholesterol Ratio (MHR) can predict the development of sarcopenia has not yet been established. …”
Get full text

Intra-operative nasal compression after lateral osteotomy to minimize post-operative Peri-orbital ecchymosis and edema by L. Sowerby, L. M. Kim, W. Chow, C. Moore

“…Objective To determine whether applying direct lateral nasal pressure intraoperatively immediately after performing lateral osteotomies reduces visible post-operative edema and ecchymosis. …”
Get full text

Sistem Pakar : Deteksi Dini Stres pada Masa Pandemi Covid-19 Menggunakan Metode Forward Chaining by Angga Wijaya Narwa Putra, Nadea Cipta Laksmita

“…Therefore, the researcher intends to make a simple expert system using knowledge obtained from an expert, then made a list of questions to detect whether someone is depressed / stressed or not, and provide solutions or suggestions for users. …”
Get full text

Marine ecological information prediction by using adjacent location spatiotemporal deep learning model with ensemble learning techniques by Yue-Shan Chang, Shu-Ting Huang, Basanta Haobijam, Satheesh Abimannan, Takayuki Kushida

“…We test our model in the Penghu Sea area near Taiwan (Penghu, Dongji, Qimei, Jibei, Jiangjun, and Wangang) using data from the Central Weather Bureau (CBW) from 2020 to 2022. The ensemble techniques employed include STH-MLR-LSTM, STH-AGG-LSTM, STH-MAE-LSTM, and STH-SAM-LSTM. …”
Get full text

Simulation and analysis of marine hydrodynamics based on the El Niño scenario by M. Ikhwan, R. Wafdan, Y. Haditiar, M. Ramli, Z. Muchlisin, S. Rizal

“…Winds blow from the west to the east of the area in perfect El Niño weather, with a reasonably high wind zone near the equator (forming a cosine). …”
Get full text