Efficacy and Safety of Low-Dose Lenvatinib and Toripalimab in Patients With Recurrent Platinum-Resistant Ovarian Cancer: Study Protocol of a Multicenter, Open-Label, Single-Arm, Ph... by Su H, Shang X, Liu H, Wang Y, Yu Y, Xu Y, Jiang K, Feng F

“…Our previous pilot study indicated that a reduced starting dose of lenvatinib may maintain comparable anti-tumor activity with favorable safety in heavily pre-treated ovarian cancer. …”
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The Effects of Presenting AI Uncertainty Information on Pharmacists’ Trust in Automated Pill Recognition Technology: Exploratory Mixed Subjects Study by Jin Yong Kim, Vincent D Marshall, Brigid Rowell, Qiyuan Chen, Yifan Zheng, John D Lee, Raed Al Kontar, Corey Lester, Xi Jessie Yang

“…Our findings reveal that pharmacists have a favorable disposition toward trusting automation. Moreover, providing uncertainty information about the AI’s recommendation significantly boosts pharmacists’ trust in AI aid, highlighting the importance of developing transparent AI systems within health care.…”
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Oncolytic virus OH2 extends survival in patients with PD-1 pretreated melanoma: phase Ia/Ib trial results and biomarker insights by Juan Li, Xuan Wang, Li Zhou, Jun Guo, Lu Si, Bixia Tang, Chuanliang Cui, Xiaoting Wei, Xinan Sheng, Siming Li, Zhihong Chi, Lili Mao, Bin Lian, Xieqiao Yan, Yan Kong, Caili Li, Xiangyong Gu, Binlei Liu, Hui Tian, Han Hu

“…A phase III clinical trial is ongoing in China (NCT05868707).Conclusions OH2 oncolytic virotherapy exhibited a favorable safety profile without dose-limiting toxicities (DLTs) and demonstrated durable antitumor efficacy in patients with melanoma, especially in those who had progressed on anti-PD-1 treatment.Trial registration number ClinicalTrials.gov identifier NCT04386967.…”
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Interacciones docente-estudiantes y maltrato infantil: análisis microgenético desde la perspectiva sociocultural/ Teacher-Student Interactions and Child Abuse: Microgenetic Analysi... by María Natalia Rodríguez, Julian David Torres, Mónica Roncancio

“… Español Esta investigación tiene como objetivo caracterizar las significaciones sobre el maltrato infantil, que emergen en el contexto de un salón de clases de primero de primaria, en un colegio público de la ciudad de Bogotá. …”
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Effectiveness of ertugliflozin during Ramadan fasting in patients with type 2 diabetes mellitus: a real-world study (ErtuRamadan study) by Md Faruque Pathan, Nazma Akter, Marufa Mustari, M. Saifuddin, Mirza Sharifuzzaman, Mohammad Motiur Rahman, Mohammed Ripon, S. M. Mohiuddin, A. B. M. Kamrul-Hasan, Mohammad Abdul Hannan, Muhammad Shah Alam, Samira Mahjabeen, Faria Afsana, Muhammed Abu Bakar, Tahniyah Haq, Afsar Ahammed, Samir Kumar Talukder, Sourav Sarkar, Shahjada Selim

“…Hypoglycemia was reported in 0.3% of the ertugliflozin group and 0.7% of the other group, with comparable adverse events (p=.23; ≥0.05), indicating a favorable safety profile for ertugliflozin during fasting.ConclusionThis study demonstrates that ertugliflozin is effective and safe for patients with T2DM during Ramadan fasting.…”
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Targeting aldose reductase using natural African compounds as promising agents for managing diabetic complications by Miriam E. L. Gakpey, Shadrack A. Aidoo, Toheeb A. Jumah, George Hanson, Siyabonga Msipa, Florence N. Mbaoji, Omonijo Bukola, Palesa C. Tjale, Mamadou Sangare, Hedia Tebourbi, Olaitan I. Awe

“…The ADMET and protein-ligand interaction results revealed that these compounds interacted with key inhibiting residues through hydrogen and hydrophobic interactions and demonstrated favorable pharmacological and low toxicity profiles. …”
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Efecto del período de conservación sobre algunas propiedades nutracéuticas y organolépticas en los bulbos de cultivares nacionales de cebollas (allium cepa l.) en el valle inferior... by M. C. Pozzo Ardizzi, M. Abrameto, G. Pellejero, G. Aschkar, M.I. Gil, A VAN KONIJNEMBURG

“…Los resultados de Pungenica determinaron que todos los cultivares fueron inicialmente «moderadamente pungentes», y salvo Antártica INTA que logró mantenerse, los demás descendieron a «pobremente pungentes». …”
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Research status and future prospect of carbon capture technology using steel slag in the context of carbon neutrality by Lei AN, Xiaoyuan ZHANG, Yu LIU

“…As an alkaline solid waste, steel slag not only offers favorable accessibility but also serves as a promising resource for high-value recycling. …”
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Exploring the benefits and prescribing informations of combining East Asian herbal medicine with conventional medicine in the treatment of rheumatoid arthritis: A systematic review... by Hee-Geun Jo, Jihye Seo, Eunhye Baek, Donghun Lee

“…EACM was associated with higher ACR responses: ACR 20 (RR: 1.2332; 95 % CI: 1.1852–1.2831, p < 0.0001), ACR 50 (RR: 1.3782; 95 % CI: 1.2936–1.4684, p < 0.0001), and ACR 70 (RR: 1.7084; 95 % CI: 1.5555–1.8762, p < 0.0001), as well as a favorable AEI (OR: 0.3977; 95 % CI: 0.3476–0.4551, p < 0.0001), indicating both better efficacy and safety compared to CM alone. …”
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Biological characterization of novel Escherichia coli O157:H7 phages and their bacteriostatic effects in milk and pork by Qinghai Ren, Qinghai Ren, Qinghai Ren, Zhiwei Wang, Yichen Ge, Yucui Huang, Wei Zhang, Chunxue Liu, Yubao Li, Shengliang Cao

“…The phages effectively inhibited host bacteria in LB broth for at least 6 h and showed promise in inhibiting bacteria in milk and pork, which indicated that the two phages exhibited a favorable bacteriostatic effect on milk and pork within the first 6 h under the optimal MOI. …”
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Designing a Model for Credit Risk Assessment of Customers for Guarantees Issued by the Export Guarantee Fund of Iran via Artificial Neural Network Model by Farshid Ahmadi Sartakhti, Kambiz Hojabr Kiani, Seyed Shamsoddin Hoseini, Abbas Memarnejad

“…Even a one percent reduction in the fund's losses could result in substantial savings, amounting to at least 1,330 billion Rials. …”
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Treatment of chronic hepatitis C by cepeginterferon alpha-2b in combination to ribavirin by M. V. Mayevskaya, O. O. Znoyko, Ye. A. Klimova, S. L. Maximov, S. N. Kizhlo, N. A. Petrochenkova, F. I. Nagimova, Yu. N. Linkova

“…As no distinctions in Algeron efficacy were revealed, at more favorable safety profile of low doze, the therapeutic doze of 1,5 mkg /kg/wk has been chosen. …”
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Epidemiología de los nematodes gastrointestinales en caprinos lecheros en los valles templados del NOA, Argentina by V.H. SUAREZ, M. FONDRAZ, A.E. VIÑABAL, G.M. MARTÍNEZ, A.O. SALATIN

“…Además, se puede determinar que el período de riesgo se presenta desde el inicio del verano hasta mediados de otoño y que el riego ofrece condiciones favorables para la supervivencia de los vermes durante el periodo seco.…”
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Implementación de buenas prácticas agrícolas para la gestión ambiental rural by Ailin SOMOZA, Patricia VAZQUEZ, Laura ZULAICA

“…Es posible concluir que la mayor parte de los procesos y acciones llevadas a cabo en el establecimiento rural son favorables para la puesta en marcha de dichas prácticas. …”
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Antimicrobial Resistance Surveillance of Skin and Soft Tissue Infections: Hospital-Wide Bacterial Species and Antibiograms to Inform Management at a Zonal Tertiary Hospital in Mwan... by Justine BN, Mushi MF, Silago V, Igembe Z, Muyombe J, Kishengena PP, Michael Jnr NS, Maganga MG, Massenga A, Tegete F, Massaga FA, Seni J

“…Revisiting SSTIs treatment guidelines at BMC and inclusion of SSTIs in the on-going AMR surveillance in Tanzania are recommended.Plain Language Summary: Tanzania National Action Plan on combating resistant bugs is exclusively focused on urinary tract infections and blood stream infections despite enormous impact conferred by skin and soft tissue infections.Bugs which are resistant to commonly used antibiotics were found more among patients admitted in the hospital in contrast to those attending outpatient clinics.This study highlights a pressing need to develop treatment guidelines based on generated local research-evidence to foster favorable patients’ outcomes.Keywords: skin and soft tissue infections, antimicrobial resistance, surveillance, Tanzania…”
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Conocimientos sobre la lectoescritura emergente y prácticas en las aulas para su promoción: Un estudio con docentes de Educación preescolar en Costa Rica/ Emergent Literacy Knowled... by Luis Diego Conejo, Ana María Carmiol

“…Una muestra conformada por 284 docentes a cargo de salones de educación preescolar contestó un cuestionario en línea. …”
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Neoadjuvant atezolizumab plus bevacizumab prior liver transplantation for hepatocellular carcinoma by Parissa Tabrizian, Rebecca Marino, Sherrie Bhoori, Marcus Zeitlhoefler, Neil Mehta, Vanessa Banz, Salvatore Gruttadauria, Massimo Iavarone, Chiara Mazzarelli, Nicolò Simonotti, Francis Yao, Vincenzo Mazzaferro, Josep M. Llovet

“…Conclusions: This study highlights the favorable oncological and survival outcomes associated with atezolizumab and bevacizumab treatment in the pre-LT setting. …”
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Assessment of Impact of Meteorology and Precursor in Long-term Trends of PM and Ozone in a Tropical City by Christian Mark G. Salvador, Angeles D. Alindajao, Karen B. Burdeos, Mark Anthony M. Lavapiez, Jhon Robin Yee, Angel T. Bautista, Preciosa Corazon B. Pabroa, Rey Y. Capangpangan

“…The increasing O3 trend was attributed to the contribution of anthropogenic VOCs (AVOCs), based on their ozone-forming potentials (OFPs). …”
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El nabo como recurso forrajero invernal en la producción de carne by O.D. BERTÍN, J.N. CAMARASA, J.O. SCHENEITER, J.P ZUVILIVIA

“…El nabo forrajero puro, sin embargo, permitió tener mayor carga animal en los períodos de clima más favorable.…”
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Àkànlò-èdè Tuntun Nínú Àwọn Orin Ọ ̀ dọ ́ Ìwòyí by Dayo Akanmu

“…Tío ̣ ́ rì èdè ojoojúmó (̣ Standard Language Theory) tí Mukarovsky ṣe agbáterù re ̣ ̀ ni a fi ṣe àtúpalè àwọn àkànlò èdè Yorùbá ̣ tuntun tí á yè wò nínú bébà yìí nítorí pé ó lè ṣàlàyé ohun tí ó je ̣ ̣ ́ kí àkànlò èdè Yorùbá tuntun yapa si èdè ojoojúmo ̣ ́ àti ohun tí ó ń fa ìyàtò gír ̣ íkì láàrin èdè ojoojúmó àti èdè ewì. …”
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