Host 3' flap endonuclease Mus81 plays a critical role in trimming the terminal redundancy of hepatitis B virus relaxed circular DNA during covalently closed circular DNA formation. by Hu Zhang, Quanxin Long, Yuanjie Liu, Alexander L Marchetti, Cheng-Der Liu, Ning Sun, Haitao Guo

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Design and experiment of air-suction drum-type seedling seeder for irregular-shaped vegetable seeds by Yanjun Li, Yunqiang Liu, Yichao Ning, Hongxin Wu, Yaqian Zhao

“…Abstract In order to meet the requirements of hole tray seedling transplanting operation for tomato, pepper and other irregular-shaped vegetable seeds, and to solve the problems of poor seeding performance of irregular-shaped vegetable seeder, this study designed an Air-suction Drum-type Precision Seeder. …”
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A generative model for evaluating missing data methods in large epidemiological cohorts by Lav Radosavljević, Stephen M. Smith, Thomas E. Nichols

“…For example, in the UK Biobank missing data tends to appear in blocks, because non-participation in one of the sub-studies leads to missingness for all sub-study variables. …”
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Six events that shaped antibody approvals in oncology by Suman Paul, Suman Paul, Shibin Zhou, Shibin Zhou

“…While the use of ADC and BsAb formats and the current rapid pace of approvals appear routine and almost inevitable, such progress was thought to be quite improbable in the early days of therapeutic antibody development. …”
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Quantifying primary oxidation products in the OH-initiated reaction of benzyl alcohol by R. S. Buenconsejo, S. M. Charan, J. H. Seinfeld, J. H. Seinfeld, P. O. Wennberg, P. O. Wennberg

“…The fraction of OH addition leading to HBA formation <span class="inline-formula">(36±18) <i>%</i></span> also does not appear to vary with [NO]. Consistent with the known high SOA yields of catechol, we find that HBA has a very high secondary organic aerosol (SOA) yield. …”
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Spatial-temporal characteristics and influence factors of high-quality development of animal husbandry industry in China. by Tiantian Su, Cuixia Li

“…According to the defining characteristics of high-quality development in animal husbandry, this paper establishes a comprehensive evaluative indicator system. …”
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Do oversimplified durability metrics undervalue biochar carbon dioxide removal? by A J Ringsby, K Maher

“…Without provisions for these factors, we find that existing assessment models appear to discount the removal value of biochar projects significantly. …”
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Nature-derived microneedles with metal-polyphenolic networks encapsulation for chronic soft tissue defects repair: Responding and remodeling the regenerative microenvironment by Chengyang Zhu, Zun Fan, Zhijie Cheng, Jun Yin, Lei Qin, Xin Zhao

“…To enhance the intrinsic bioactivities, metal-polyphenolic networks (MPNs) coordinated from copper (Cu) and curcumin (Cur) are designed and encapsulated into NMs. …”
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Design and assessment of lipase-CuO nanoparticle conjugates for enhanced antimicrobial efficacy against clinical pathogens by Eman M. Handak, Dina H. Amin, Mai M. Elhateir

“…Also, CuO nanoparticles appeared as distinct, well-dispersed spherical particles with average size of 71.035 nm using TEM, while conjugate appears as large protein molecules linked to the nanoparticles. …”
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Proximate, Mineral Contents and Physicochemical Properties of <i>Chrysophyllum Albidum</i> (African Star Apple) Kernel Flour and Oil by S.S. Audu, C.I. Beetseh, D.U. Edward-Ekpu, A.A. Ewuga

“…The results from the Mineral Analysis showed the kernel has 0.01 mg/g of copper, 0.01 mg/g of Iron, 37.50 mg/g of phosphorus, 57.37 mg/g of calcium and 0.44 mg/g magnesium. …”
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Cerebrovascular accidents association between serum trace elements and toxic metals level, a case-control study. by Khosro Jamebozorgi, Alireza Kooshki, Mahbobeh Saljoughi, Mohamadjavad Sanjari, Zahra Ahmadi, Seyed Mohammad Mosavi Mirzaei

“…The serum level of several metals, including Fe (Iron), Co (Cobalt), Ni (Nickel), Cu (copper), Zn (Zinc), Mn (Manganese), Pb (lead), Hg (Mercury), has been assessed using Inductively coupled plasma mass spectrometry (ICP-MS) method. …”
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Algorithm of management of patient with alcohol-induced liver disease by M. V. Mayevskaya, M. A. Morozova

“…Manifestation of disease usually appear after another episode of alcohol intake. Severe alcoholic hepatitis, especially if develops on a background of pre-existing LC, in high number of cases is associated to unfavorable life prognosis. …”
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Assessing the impact on mode competitiveness of improvements of the Trans-Eurasian railway network by Seyed Mohseni, Edwin van Hassel, Thierry Vanelslander

“…However, by far the largest volumes of transport still happen by maritime transport. The third and main question of the paper is on whether the land bridge by rail would cost-wise be competitive enough to favour a large shift from sea to land. …”
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Dissemination of Evidence-Based Recommendations for Sickle Cell Disease to Primary Care and Emergency Department Providers in North Carolina: A Cost Benefit Analysis by Paula Tanabe, Audrey L. Blewer, Emily Bonnabeau, Hayden B. Bosworth, Denise H. Clayton, Nancy Crego, Marian F. Earls, Kern Eason, Grayson Forlines, Gary Rains, Matthew Young, Nirmish Shah

“…**Background:** Sickle cell disease (SCD) is a genetic condition affecting primarily individuals of African descent, who happen to be disproportionately impacted by poverty and who lack access to health care. …”
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Health Care Costs attributable to Hospital-diagnosed Back Pain: A Longitudinal Register-based Study of the Danish Population by Rikke Søgaard, Jan Sørensen

“…**Conclusion:** At the disease stage where back pain leads to contact with specialised health care, diseased individuals appear to use on average three times more health care than non-diseased individuals. …”
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Discrete coordination nanochains based on photoluminescent dyes reveal intrachain exciton migration dynamics by Ryojun Toyoda, Naoya Fukui, Haru Taniguchi, Hiroki Uratani, Joe Komeda, Yuta Chiba, Hikaru Takaya, Hiroshi Nishihara, Ryota Sakamoto

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Travel Burden and the Direct Medical Costs of Urologic Surgery by Daniel J. Olson, John L. Gore, Kenn B. Daratha, Kenneth P. Roberts

“…**Conclusions:** Patient travel burden does appear to play a role in cost and length of hospital stay for select urologic procedures with variable levels of morbidity and recovery time. …”
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Traditional Chinese Medicine Prescription Generation Model Based on Search Enhancement by ZHAO Zijuan, REN Xueting, SONG Kai, QIANG Yan, ZHAO Juanjuan, ZHANG Junlong

“…In addition, the proposed model can recommend herbs that do not appear on the prescription label but are useful for relieving symptoms, which shows that the model can learn some interactions between herbs and symptoms. …”
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Cu-32.02% Zn-2.30% Pb alloy surface superhydrophobicity induced by an arachidate layer by Aniedi E. Nyong, Godwin J. Udoh, Joachim J. Awaka-Ama, Joshua F. Effiong, Ifiok Ekwere, Clement Obadimu, Pradeep Rohatgi

“…These products existed in various nanostructural forms on the copper alloy surface. The average contact angles of water measured after the chemical modification step were 153.73 ± 7.35 and 144.94 ± 0.78 for the samples modified in 0.005 M arachidic acid for 6 and 12 hours, respectively.…”
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Causes of the exceptionally high number of fatalities in the Ahr valley, Germany, during the 2021 flood by B. Rhein, B. Rhein, H. Kreibich

“…Specific recommendations for disaster management are (1) that in the event of such extreme flash floods, the warning messages must focus on saving human lives – i.e. those at risk must be advised to move to safe places, e.g. to the upper floors, instead of trying to save belongings – and (2) evacuations must be initiated in good time, especially where flooding of the ground floor with high water levels is to be expected, paying particular attention to the safety of the elderly and people with limited mobility.…”
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