The case for development of a core outcome set (COS) and supplemental reporting guidelines for influenza vaccine challenge trial research in swine by Sheila Keay, Famke Alberts, Annette M. O’Connor, Robert Friendship, Terri O’Sullivan, Zvonimir Poljak

Subjects: “…core outcome set (COS)…”
Get full text

Membrane-bound model of the ternary complex between factor VIIa/tissue factor and factor X by Melanie P. Muller, Alex Mortenson, Josepha C. Sedzro, Po-Chao Wen, James H. Morrissey, Emad Tajkhorshid

“…These findings underscore the substrate-binding exosite of TF as being pivotal in the formation of the EC, serving as a critical interface linking the GLA domains of both FVIIa and FX.…”
Get full text

Yiqi Juanshen decoction alleviates renal interstitial fibrosis by targeting the LOXL2/PI3K/AKT pathway to suppress EMT and inflammation by Kaiyue Tan, Jingwei Deng, Yi Liu, Yudi Zhang, Yu Xiong, Su Yuan, Jun Liu, Zhiwei Chen, Yuanyuan Liu, Wenfu Cao

“…These findings suggest that YQJSD may serve as a promising therapeutic management of RIF in CKD patients.…”
Get full text

Dose-dependent effects of hydroquinone on liver injury and lipid dysregulation based on SCD1/AMPK signaling pathway in C57BL/6 mice by Lijun Zou, Fen Lin, Jinying Wen, Jinyu Huang, Yue Tan, Hui Huang, Gonghua Hu

Subjects: Get full text

Transcranial vibration stimulation at 40 Hz induced neural activity and promoted the coupling of global brain activity and cerebrospinal fluid flow by Linghan Kong, Wei Jin, Yue Jiang, Fuhua Yan, Jun Liu, Eric C. Leuthardt, Guang-Zhong Yang, Yuan Feng

“…Additionally, this study investigates alterations in the global blood-oxygen-level-dependent (gBOLD) signal and cerebrospinal fluid (CSF) inflow coupling, which serve as indicators of glymphatic system function. …”
Get full text

Lipids in parenteral nutrition – expert consensus statements: Translating guidelines into clinical practice by Robert G. Martindale, Philip C. Calder, Sarah V. Cogle, David C. Evans, Leah Gramlich, Stephen A. McClave, Manpreet S. Mundi, Maurizio Muscaritoli, Reid Nishikawa, Jayshil Patel, Lorenzo Pradelli, Martin Rosenthal, Christian Stoppe, Kelly A. Tappenden, Malissa Warren, Dan Waitzberg, Paul E. Wischmeyer, Stanislaw Klek

“…Summary: Lipids are integral to parenteral nutrition (PN) in all settings where PN is required, serving as a source of energy and essential fatty acids. …”
Get full text

ZBiotics ameliorates T2DM-induced histopathological damage in liver, kidney and adipose tissues by modulating the NOD-like receptor signaling in Wistar rats by Mohammed Esawie, Marwa Matboli, Mariam Sameh Bushra, Amany H. Hasanin, Eman Kamal Habib, Reham Hussein Mohamed, Hebatalla Said Ali

“…Abstract Probiotics serve as promising candidates in type 2 diabetes mellitus (T2DM) therapy. …”
Get full text

Charge-on-the-move solutions for future mobility: A review of current and future prospects by Mohd Aiman Khan, Wilco Burghout, Oded Cats, Erik Jenelius, Matej Cebecauer

Subjects: “…Autonomous electric vehicles (AEVs)…”
Get full text

Revealing intra- and inter-container fruit quality heterogeneity within overseas refrigerated container shipments using a physics-based digital twin by Celine Verreydt, Tarl Berry, Leo Lukasse, Deniz Turan, Paul Cronje, Thijs Defraeye

“…Overall, the digital twin serves as a first step towards real-time quality monitoring within fresh fruit supply chains.…”
Get full text

Integration of ground-based and remote sensing data with deep learning algorithms for mapping habitats in Natura 2000 protected oak forests by Lucia Čahojová, Ivan Jarolímek, Barbora Klímová, Michal Kollár, Michaela Michalková, Karol Mikula, Aneta A. Ožvat, Denisa Slabejová, Mária Šibíková

“…The most distinguishing differences in band characteristics between the two oak-dominated habitats were observed during the autumn months.This study presents a framework that integrates terrestrial and remote sensing data. This method can serve as a basis for mapping forest habitats and observing changes related to climate change. …”
Get full text

Redox-mediated reverse water gas shift integrated with ammonia cracking over Ni/La0.75Sr0.25Cr0.5Mn0.5O3−δ by Martin Keller, Shih-Yuan Chen, Atul Sharma

“…NH3 and CO2 can react to produce syngas (H2 + CO), which serves as a feedstock for the production of chemicals or synthetic fuels. …”
Get full text

Effectiveness of dupilumab treatment against refractory eosinophilic chronic rhinosinusitis by Daiki Nakashima, MD, Tsuguhisa Nakayama, MD, PhD, Shunsuke Minagawa, MD, PhD, Tetsuya Adachi, MD, PhD, Chieko Mitsuyama, MD, Yoko Shida, MD, Tsuneya Nakajima, MD, PhD, Shin-ichi Haruna, MD, PhD, Yoshinori Matsuwaki, MD, PhD

“…Conclusions: Dupilumab shows effectiveness in treating ECRS and could serve as an alternative therapeutic option to systemic corticosteroids. …”
Get full text

Identification of Plasma Proteins Associated with Alzheimer's Disease Using Feature Selection Techniques and Machine Learning Algorithms by Zakaria Mokadem, Mohamed Djerioui, Bilal Attallah, Youcef Brik

“…This study aims to use computational algorithms to explore the relationship between plasma proteins and AD progression by identifying a panel of plasma proteins that can serve as biomarkers for tracking and diagnosing AD. …”
Get full text

Adipocyte heterogeneity and tumor infiltration of adipose tissue in patients with metastatic breast cancer by Hava Izci, Gitte Zels, Anirudh Pabba, Marion Maetens, François Richard, Maxim De Schepper, Josephine Van Cauwenberge, Ha-Linh Nguyen, Kristien Borremans, Sophia Leduc, Karen Van Baelen, Sigrid Hatse, Tatjana Geukens, Amena Mahdami, Hans Wildiers, Patrick Neven, Wouter Van Den Bogaert, Giuseppe Floris, Christine Desmedt

“…Background: The adipose tissue may serve as a source of energy supporting cancer growth and metastasis. …”
Get full text

Habitat fragmentation increases the risk of local extinction of small reptiles: A case study on Phrynocephalus przewalskii by Cui Yang, Yue Qi, Jiayuan Guo, Liangfei Peng, Neng Xiong, Wenya Zhang, Wei Zhao

“…Reptiles, particularly smaller species with limited migratory abilities, are especially vulnerable to these changes. …”
Get full text

Molecular mechanisms of cis-oxygen bridge neonicotinoids to Apis mellifera Linnaeus chemosensory protein: Surface plasmon resonance, multiple spectroscopy techniques, and molecular... by Xiangshuai Li, Shiyu Li, Yang Liu, Li Cui, Daibin Yang, Shuning Chen, Xusheng Shao, Huizhu Yuan, Xiaojing Yan

“…The findings revealed that hydrogen bonding and hydrophobic interactions serve as the primary forces driving the binding process, with fluorescence quenching mechanisms involving both dynamic and static interactions. …”
Get full text

Exploration of interstitial fluid proteome in Homo sapiens forearm through a cutting edge intradermal microdialysis and high-throughput proteomics approach: a pilot study by Yu Sakamoto, Naoto Fujii, Junko Shibato, Ravi Gupta, Cheol Woo Min, Sun Tae Kim, Ranjith Kumar Bakku, Randeep Rakwal

“…Nonetheless, skin dialysate may serve as an alternative for blood, yet further research is vital to clarify its potential for real-time continuous monitoring applications within sports science research and practices. …”
Get full text

Adults with reading difficulties demonstrate selective impairments in the fine neural tuning for print by Tongjie Zhuang, Yaowen Li, Yufei Tan, Jiuju Wang, Xiuyue Yue, Licheng Xue, Jing Zhao, Jing Zhao

“…IntroductionNeural tuning for print, reflected in differential responses of the N170 component of event-related potentials to orthographic forms and other visual stimuli, serves as the neural basis for efficient visual word reading. …”
Get full text

Finite-Time Output Robust Control for Restricted Joint Flight Emulator Robotic Arm With Adaptive Tangent Barrier Gains by Isaac Chairez, Alejandra Hernandez-Sanchez, Caridad Mireles, Arthur Mukhamedov, Grigory Bugriy, Stepan Lemak, Viktor Chertopolokhov

“…A standard state feedback control architecture serves as a benchmark for comparison. The origin is shown to be a fixed-time stable equilibrium point for the tracking error space, provided state space constraints are met, as evidenced by the faster convergence of the mean square estimation of the tracking error. …”
Get full text

Clinicopathological characteristics and long-term prognosis of triple-negative breast cancer patients with HER2-Low expression: a retrospective propensity score-matched cohort stud... by Xin Liu, Kaihua Zhao, Ziyan Zhang, Meiyan Liu, Hongwu Chu, Xiao Zou

“…Compared to HER2-zero, HER2-low status is linked to better long-term prognosis and serves as an independent low-risk factor for RFS in TNBC patients.…”
Get full text