Efficacy and safety of camrelizumab combined with chemotherapy as second-line treatment for locally advanced, recurrent, or metastatic esophageal squamous cell carcinoma by Yinfang Gu, Xiaofang Zou, Junlin Zhu, Guowu Wu

“…Abstract Background This study aims to evaluate the efficacy and safety of camrelizumab in combination with chemotherapy as a second-line treatment for patients with locally advanced, recurrent, or metastatic esophageal squamous cell carcinoma (ESCC). Methods In this retrospective, single-center observational study, we collected medical records of patients with locally advanced, recurrent, or metastatic ESCC who received either camrelizumab combined with chemotherapy or chemotherapy alone as second-line treatment between July 1, 2019, and May 31, 2023. …”
Get full text

Unravelling the interplay of nitrogen nutrition and the Botrytis cinerea pectin lyase BcPNL1 in modulating Arabidopsis thaliana susceptibility by Antoine Davière, Aline Voxeur, Sylvie Jolivet, Luka Lelas, Samantha Vernhettes, Marie-Christine Soulié, Mathilde Fagard

“…Our findings revealed that infected detached leaves from nitrogen-sufficient plants released more pectin lyase (PNL)-derived oligogalacturonides compared to nitrogen-deficient ones. …”
Get full text

Eastern equine encephalitis virus: Pathogenesis, immune response, and clinical manifestations by Bhumika Parashar, Rishabha Malviya, Sathvik Belagodu Sridhar, Tarun Wadhwa, Sirajunisa Talath, Javedh Shareef

“…Eastern equine encephalitis virus (EEEV) is a lethal Alphavirus transmitted by Culiseta melanura mosquitoes that primarily cycles between birds. …”
Get full text

Effectivity of Mangkokan Leaf Extract (Nothopanax scutellarium Merr) with Different Treatments to Control Golden Snail (Pomacea canaliculata Lamarck) by Rusdi Rusli, Imelda Sari, Munzir Busniah

“… Mangkokan leaves (Nothopanax scutellarium Merr) have been used to control golden snail (Pomacea canaliculata Lamarck) in several preparations. …”
Get full text

Grasshopper Nematode: Mermis nigrescens Dujardin, 1842 by John L. Capinera

“…These large nematodes can sometimes be seen leaving grasshoppers, especially those that have been injured. …”
Get full text

The surgical time-out: the relationship between perceptions of a safety-task anchor and surgical team workflow by Vivian J. Zagarese, Ivan Hernandez, Neil M. A. Hauenstein, Roseanne J. Foti, Sarah H. Parker

“…Results The relationship of the length of the time-out with the rate at which the nurse leaves the OR was non-significant (β = 0.089, p = .496). …”
Get full text

Native Pitcherplants of Florida by Megan E. Brown, Debbie L. Miller

“…Pitcherplants are perennial plants with groups of leaves modified into traps or pitchers. They have tubular leaves with lids or hoods at the top that secrete nectar to attract prey. …”
Get full text

Magnesium (Mg) for Citrus Trees by Mongi Zekri, Tom Obreza

“…Magnesium deficiency symptoms occur on mature leaves following the removal of Mg to satisfy fruit requirements. …”
Get full text

ENTPD8 overexpression enhances anti-PD-L1 therapy in hepatocellular carcinoma via miR-214-5p inhibition by Si-qi Zhao, Min-jie Chen, Fei Chen, Zhao-feng Gao, Xiao-ping Li, Ling-yu Hu, Hai-ying Cheng, Jin-yan Xuan, Jian-guo Fei, Zheng-wei Song

“…These findings suggest that ENTPD8 may serve as a prognostic marker and therapeutic target for HCC, offering potential strategies for improving treatment outcomes.…”
Get full text

A Successful Heat Wave Prevention in Ahmedabad Calls for Segregated Health Record: Highlights from Existing Heat Action Plan by Priya Dutta, Prashant Rajput, Polash Mukherjee, Prima Madan, Dileep Mavalankar

“…The Ahmedabad HAP can serve as a model for other cities across South Asian nations interested in intervention strategies against excessive heat. …”
Get full text

Modeling and designing enhancers by introducing and harnessing transcription factor binding units by Jiaqi Li, Pengcheng Zhang, Xi Xi, Liyang Liu, Lei Wei, Xiaowo Wang

“…Abstract Enhancers serve as pivotal regulators of gene expression throughout various biological processes by interacting with transcription factors (TFs). …”
Get full text

An EEG dataset for interictal epileptiform discharge with spatial distribution information by Nan Lin, Mengxuan Zheng, Lian Li, Peng Hu, Weifang Gao, Heyang Sun, Chang Xu, Gonglin Yuan, Zi Liang, Yisu Dong, Haibo He, Liying Cui, Qiang Lu

“…Additionally, our dataset serves as a reliable test set for evaluating and comparing existing IED detection models.…”
Get full text

A Research-Informed Approach to Curriculum Development: Designing a Vocational English Course for a Specific Topic in Graphic Design by Ahmad Syairofi, Suwarno Suwarno

“… Since the inception of vocational secondary schools in Indonesia, the English curriculum for such schools has been considered general English rather than vocational English, which serves as the medium of English learning for the students’ future work. …”
Get full text

Designing and developing a prescription digital therapeutic for at-home heart rate variability biofeedback to support and enhance patient outcomes in post-traumatic stress disorder... by Rebecca Macy, Flavio Somanji, Flavio Somanji, Oleksandr Sverdlov

“…These processes might in turn improve treatment-seeking, adherence, and supported self-management of these conditions.…”
Get full text

Advances and challenges in platelet counting: evolving from traditional microscopy to modern flow cytometry by Chen Yong, Hu Yonggang, Hu Hai

“…Platelet counting is a fundamental clinical test for diagnosing haemorrhagic diseases, coagulation abnormalities, and certain autoimmune disorders, and it also serves as a critical basis for decisions regarding platelet transfusion. …”
Get full text

TEFM facilitates transition from RNA synthesis to DNA synthesis at H-strand replication origin of mtDNA by Shigeru Matsuda, Masunari Nakayama, Yura Do, Takashi Ishiuchi, Mikako Yagi, Sjoerd Wanrooij, Kazuto Nakada, Fan-Yan Wei, Kenji Ichiyanagi, Hiroyuki Sasaki, Dongchon Kang, Takehiro Yasukawa

“…In strand-asynchronous mtDNA replication, transcripts from the light-strand promoter serve as primers for leading-strand synthesis at the origin of the H-strand replication (OH). …”
Get full text

A Study on the Quality of Mashhur Ghairu Istilahi Hadith: Reconsidering the Stereotype of Misogynistic Hadiths by Frenky Mubarok, Suci Muzfirah, Muidatul Faziyah

“… Hadith serves as the second authoritative source of Islamic teachings after the Qur’an, functioning either to elucidate the Qur’an or to supplement aspects not explicitly addressed within it, thereby guiding the religious practices of Muslims. …”
Get full text

Ferroelectricity in van der Waals multilayers via interfacial polarization engineering by Xiaokai Chen, Xiaoyu Xuan, Wanlin Guo, Zhuhua Zhang

“…Then, the interfacial polarization and enhanced interlayer polarization can serve as two elements for building robust ferroelectrics from vdW multilayers with cumulative, thickness-controllable polarization. …”
Get full text

GTAT: empowering graph neural networks with cross attention by Jiahao Shen, Qura Tul Ain, Yaohua Liu, Banqing Liang, Xiaoli Qiang, Zheng Kou

“…Abstract Graph Neural Networks (GNNs) serve as a powerful framework for representation learning on graph-structured data, capturing the information of nodes by recursively aggregating and transforming the neighboring nodes’ representations. …”
Get full text

Acer japonicum 'Vitifolium' by Edward F. Gilman

“…The hanging clusters of showy, purple/red flowers appear in late spring and are followed by the production of winged seeds. The flowers stand out among the maples. This document is FPS 8, one of a series of the Environmental Horticulture Department, Florida Cooperative Extension Service, Institute of Food and Agricultural Sciences, University of Florida. …”
Get full text