Lower urinary dysfunction as a long-term effect of childhood vincristine treatment, with potential influences by sex and dose by Nao Iguchi, Ali Teimouri, Duncan T. Wilcox, Anna P. Malykhina, Nicholas G. Cost

“…Noteworthy functional changes were observed in bladder strips from the VCR group, including decreased nerve-mediated contraction, heightened contractile responses to cholinergic and purinergic agonists, enhanced responsiveness to histamine—primarily via histamine receptor 1 (Hrh1)—and an augmented relaxation effect with compound 48/80 (a mast cell degranulator), relative to the control group. …”
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A global Corynebacterium diphtheriae genomic framework sheds light on current diphtheria reemergence by Hennart, Mélanie, Crestani, Chiara, Bridel, Sébastien, Armatys, Nathalie, Brémont, Sylvie, Carmi-Leroy, Annick, Landier, Annie, Passet, Virginie, Fonteneau, Laure, Vaux, Sophie, Toubiana, Julie, Badell, Edgar, Brisse, Sylvain

“…Methods: We developed the bioinformatics pipeline diphtOscan (available at https://gitlab.pasteur.fr/BEBP/diphtoscan) to extract from genomes of Corynebacteria of the diphtheriae species complex, medically relevant features including tox gene presence and disruption. …”
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Which social determinants of health have the highest impact in community oncology to advance patient care equity and improve health outcomes? A scoping review by Kayleigh R. Majercak, Emily F. Gorman, Nicholas J. Robert, Barbara Palmer, Henry Asante Antwi, C. Daniel Mullins

“…The study was guided by the “10‐Step Framework for Continuous Patient Engagement” and a Community Advisory Board to assure relevance to patients and community providers. Literature was retrieved from literary databases and oncology organizations' websites. …”
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Engaging primary care physicians in system change – an interpretive qualitative study in a remote and rural health region in Northern British Columbia, Canada by David Snadden, Trish Reay, Neil Hanlon, Martha MacLeod

“…Objectives To describe how physicians were engaged in primary healthcare system change in a remote and rural Canadian health authority.Design A qualitative interpretive study based on a hermeneutic approach.Methods 34 transcribed in-depth interviews with physicians and administrators relevant to physician engagement were purposively sampled from a larger data set of 239 interviews gathered over a 3-year period from seven communities engaged in primary healthcare transformation. …”
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Characterization of environmental and clinical surveillance inputs to support prospective integrated modeling of the polio endgame. by Kamran Badizadegan, Kimberly M Thompson

“…This descriptive review of poliovirus surveillance evidence as of late 2024 aims to provide national, regional, and global decision makers with an understanding of prospective tradeoffs and uncertainties and to support prospective assumptions relevant for integrated policy, poliovirus transmission, and economic modeling for 2024-2035.…”
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Amniotic fluid microbiota and metabolism with non-syndromic congenital heart defects: a multi-omics analysis by Wenli Xu, Lu Li, Hong Kang, Meixian Wang, Yanqun Liu, Guicun Wang, Ping Yu, Juan Liang, Zhen Liu

“…Abstract Background and aims Recent studies have indicated possible links between the microbiota and the fetal heart, while the relevant mechanism is still unknown. This study is aims to investigate whether analyzing the microbiota and metabolic profiles of amniotic fluid collected from pregnant women whose fetuses with or without non-syndromic congenital heart defects (CHDs), during the second and third trimester of pregnancy, could offer valuable insights into CHDs. …”
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Accuracy of administrative data for surveillance of healthcare-associated infections: a systematic review by Karel G M Moons, Marc J M Bonten, Maaike S M van Mourik, Pleun Joppe van Duijn, Grace M Lee

“…We conducted a systematic review evaluating the diagnostic accuracy of administrative data for the detection of HAI.Methods Systematic search of Medline, Embase, CINAHL and Cochrane for relevant studies (1995–2013). Methodological quality assessment was performed using QUADAS-2 criteria; diagnostic accuracy estimates were stratified by HAI type and key study characteristics.Results 57 studies were included, the majority aiming to detect surgical site or bloodstream infections. …”
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Conceptual model of sustainable development of pedagogical staff competences in quality assurance of higher education by Andrii Biloshchytskyi, Andrii Biloshchytskyi, Oleksandr Kuchanskyi, Oleksandr Kuchanskyi, Oleksandr Kuchanskyi, Yurii Andrashko, Aidos Mukhatayev, Khanat Kassenov

“…The sustainability of the development of teachers’ methodological competences is ensured by monitoring their activities based on the results of professional development and acquisition of the appropriate level of competence, as well as on the results of teaching by these teachers of relevant educational components in academic groups of higher education students. …”
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Does transcutaneous auricular vagus nerve stimulation alter pupil dilation? A living Bayesian meta-analysis by Ipek Pervaz, Lilly Thurn, Cecilia Vezzani, Luisa Kaluza, Anne Kühnel, Nils B. Kroemer

“…These findings underscore the relevance of taVNS protocols in optimizing its use for specific applications that may require modulation of tonic vs. phasic monoaminergic responses and might also help to gain mechanistic insights into potential therapeutic effects.…”
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The effect of gas and liquid phase composition on miscibility through interfacial tension measurements of model oils in compressed CO2 by Sonya Ahmadyar, Hanin Samara

“…The density of the respective CO2-saturated alkanes is measured and reported at conditions relevant to the work. The pressure has an inverse relation with IFT, while the influence of temperature depends on the pressure range investigated, and higher MMP is obtained at higher temperatures. …”
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The Relationship Between Culture and the Modifiable Risk Factors of Dementia Among Indigenous Peoples in Canada, the USA, Australia, and New Zealand: A Scoping Review Protocol by Brittany Skov, Angela M. Ashley, Ishaq Malik, Hannah Storrs, Elaine Toombs, Christopher J. Mushquash

“…We will systematically search PsychInfo, Web of Science, PubMed, ERIC, CINAHL, and gray literature databases to identify relevant qualitative and quantitative studies. Four reviewers will assess titles, abstracts, and full-text articles for inclusion. …”
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Navigating Host Immunity and Concurrent Ozone Stress: Strain‐Resolved Metagenomics Reveals Maintenance of Intraspecific Diversity and Genetic Variation in Xanthomonas on Pepper by Amanpreet Kaur, Ivory Russell, Ranlin Liu, Auston Holland, Rishi Bhandari, Neha Potnis

“…And, a high proportion of transient mutations suggest less predictable pathogen evolution under climatic alterations. This knowledge is relevant as we study the risk of pathogen emergence and the mechanisms and constraints underlying long‐term pathogen adaptation under climatic shifts.…”
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On the time spent preparing grant proposals: an observational study of Australian researchers by Nicholas Graves, Adrian G Barnett, Philip Clarke, Danielle L Herbert

“…The application process could be shortened so that only information relevant for peer review, not administration, is collected. …”
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Key challenges in providing assisted dying in Belgium: a qualitative analysis of health professionals’ experiences by Madeleine Archer, Lindy Willmott, Kenneth Chambaere, Luc Deliens, Ben P. White

“…Design: A qualitative interview study with reflexive thematic analysis. Methods: Twenty interviews were conducted between September 2022 and March 2024 using Microsoft Teams videoconferencing. …”
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Sexual distress among men with cancer – a cross-sectional study by Jonas Nahavandipour, Christoffer Johansen, Annamaria Giraldi, Bolette Skjøft Rafn, Annika von Heymann

“…Sexual distress was significantly associated with clinically relevant insomnia (OR:2.15; 95% CI:1.5–3.1) and pain (OR:1.90; 95% CI:1.3–2.9). …”
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Increasing trend of antimicrobial resistance among methicillin-resistant Staphylococcus aureus strains in Southwest Finland, 2007–2016: An analysis of shifting strain dynamics and... by Jaakko Silvola, Kirsi Gröndahl-Yli-Hannuksela, Tiina Hirvioja, Kaisu Rantakokko-Jalava, Mari Kanerva, Kari Auranen, Harri Marttila, Jenna Junnila, Jaana Vuopio

“…Methods: Antimicrobial susceptibility was determined for 10 clinically relevant antimicrobials. Strains with resistance to ≥2 antimicrobials were defined multi-resistant. …”
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Sözlü Kültür Döneminden Başlayarak Dijital Döneme Kadar Uzanan Süreçte Dil Kültür Etkileşiminin İletişim Süreçlerine Etkisi by Emine Hilal Korucu

“…Dil ve kültür alanındaki yeniliklerin etkileriyle şekillenen binlerce yıllık iletişim tarihi, iletişimin toplumsal ve bireysel yaşamdaki rolüne dair bilgiler vermektedir. Bu çerçevede ortaya çıkan yeni araçlar, iletişim biçimlerine yenilikler getirmekte ve iletişim süreçlerini dönüştürmektedir. …”
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Effect of combining different 10-MDP-containing primers and cement systems on shear bond strength between resin cement and zirconia by Kan Wongkamhaeng, Kopchai Poomparnich, Top Chitkraisorn, Kwanwong Boonpitak, Terawat Tosiriwatanapong

“…Then, each group was bonded with Panavia V5 and RelyX™ Universal resin cements. Airborne-particle abrasion on the zirconia surfaces was also conducted using the manufacturer’s bonding protocol for both resin cements. …”
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Prophylactic antibiotics in laparoscopic cholecystectomy: Reducing postoperative infection risk–A meta-analysis and trial sequential analysis by Shufeng Wang, Qing Gao, Xiaogang Qi, Lihua Hong, Hai Huang

“…Methods: Multiple databases including PubMed, Cochrane Library, EMBASE, and Web of Science were systematically searched to identify relevant randomized controlled trials (RCTs) published from inception to January 23, 2024. …”
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Phytomedicinal armamentarium: A review of inula racemosa-derived alantolactones and isoalantolactones in anticancer therapy by Joshi Gaurav Santoshrao, Smriti Jamwal, Rakesh Kumar, Ekta Bisht, Bisen Harsh Krishnakumar, Shreya Katoch, R.K. Asrani

“…Keywords like ''Inula,'' ''anticancer,'' and ''cell lines'' were employed to identify relevant studies. Initially 126 papers were screened in total and the collected data were analysed to assess the anti-cancer properties of alantolactone and isoalantolactone. …”
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