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6401
Outcomes for Dostarlimab and Real-World Treatments in Post-platinum Patients With Advanced/Recurrent Endometrial Cancer: The GARNET Trial Versus a US Electronic Health Record-Based...
Published 2023-09-01“…Additionally, patients had a long TTD when treated with dostarlimab, suggesting a favorable tolerability profile. **Conclusion:** Patients with advanced or recurrent EC receiving dostarlimab in GARNET had significantly lower risk of death than those receiving real-world non-anti-PD-(L)1/2 treatments.…”
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6402
SPA14 liposomes combining saponin with fully synthetic TLR4 agonist provide adjuvanticity to hCMV vaccine candidate
Published 2024-12-01“…When tested as an adjuvant in vivo with human cytomegalovirus glycoprotein B (gB) and pentamer complex (PC) as test antigens, SPA14 was generally well tolerated and as active as AS01B for the induction of long-lasting CMV-neutralizing antibodies in mice and non-human primates (NHPs). …”
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6403
Cerebral Cortical Activity During Academic Stress Amongst Undergraduate Medical Students at Kampala International University (Uganda)
Published 2023“…Data on reaction time were acquired through VRT, ART, and TRT using the catch-a-ruler experiment, and this was analyzed using SPSS version 20. …”
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6404
Rancang Bangun Sistem Konversi Mata Kuliah (Studi Kasus : Prodi Informatika, Fasilkom, UPN "Veteran" Jawa Timur)
Published 2022-06-01“…Kondisi lain yang seringkali terjadi adalah jumlah SKS yang berkurang dari yang dicatat oleh mahasiswa serta perbedaan nama mata kuliah. …”
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6405
Impact of a positive end-expiratory pressure on oxygenation, respiratory compliance, and hemodynamics in obese patients undergoing laparoscopic surgery in reverse Trendelenburg pos...
Published 2025-02-01“…Conclusion In patients with obesity undergoing surgery in the reverse Trendelenburg position HPEEP and iPEEP may improve oxygenation, decrease driving pressure, and increase dynamic compliance compared to LPEEP with high variation of true effect without relevant hemodynamic compromise. Data with MPEEP comparisons are inconclusive. …”
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6406
Economic Evaluation of Robotic-assisted Radical Prostatectomy: A Systematic Review and Meta-analysis
Published 2025-02-01“…We performed a systematic review and meta-analysis to pool the incremental net benefit (INB) of these approaches. Methods: Relevant CEA studies of RARP were identified by searching the PubMed, Embase, Scopus, International Health Technology Assessment database, Tufts CEA Registry, and Centre for Reviews and Dissemination databases from January 2005 to October 2023. …”
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6407
Prognostic value of body adipose tissue parameters in cancer patients treated with immune checkpoint inhibitors
Published 2025-02-01“…No significant relationship was found between TAT (HR: 0.81, 95% CI: 0.54–1.23, p = 0.332) and VSR (HR: 1.20, 95% CI: 0.95–1.51, p = 0.131) with PFS in ICI-treated patients.ConclusionThis study highlights the prognostic relevance of VAT and SAT in predicting treatment response and survival outcomes in cancer patients receiving ICIs. …”
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6408
Antioxidants in the Treatment of Chronic Diffuse Liver Diseases (the Results of the “MAXAR” Observational Program)
Published 2018-11-01“…Therefore, the elucidation of the nature of asthenic syndrome and a search for methods for its resolution seem to be highly relevant research tasks.Aim. This study aims to investigate the effect of the antioxidant drug (the extract of the Amur maackia wood) on the organic and functional components of asthenic syndrome in patients with NAFLD and ALD, who do not show signs of the disease decompensation. …”
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6409
Comparative analysis of ocular biometrics using spectral domain optical coherence tomography with Purkinje image and optic nerve head alignments in mice
Published 2025-02-01“…Gaining an understanding of the implications of these methods in determining axial elongation in the normal growing eyes of wild-type C57BL/6J mice would offer valuable insight into their relevance for the experimental myopia model. Methods Ocular dimensions and refractive development were measured on postnatal days P21 (n = 10), P28 (n = 15), and P35 (n = 8). …”
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6410
Predicting Iran Cooperative Development Bank's Profit/Loss: Two-stage Collective Learning
Published 2023-12-01“…These variables encompass interest-free loans and short-term deposits, deposit interest expenses, total customer deposits, income from facilities and investments, common income, cash balances, administrative expenses, long-term deposits, non-common income, asset depreciation expenses, and the bank's size. Relevant data for the study was obtained from the financial statements of 35 branches of the Cooperative Development Bank spanning the years 2012 to 2021. …”
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6411
Comparisons of open surgical repair, thoracic endovascular aortic repair, and optimal medical therapy for acute and subacute type B aortic dissection: a systematic review and meta-...
Published 2025-02-01“…Methods A systematic search was conducted across databases including PubMed, EmBase, and the Cochrane Library for relevant studies published from their inception up to September 2024. …”
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6412
High-performance CT features supporting accurate pre-operative tumor staging in colon cancer
Published 2025-02-01“…We aimed to pathologically interpret the key CT findings in order to identify reliable markers for pre-treatment staging of colon cancer.Patients and methodsThe following CT features from 136 colon adenocarcinomas were analyzed: colon wall pliability, outline contour, pericolic fat attenuations and vascularity, tumor fusion with adjacent organs, ascites, tumor size, and relevance between tumor and retroperitoneal fascia. …”
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6413
The Model of Disengagement of Talent with Meta-synthesis Method
Published 2024-11-01“…This selection process ensured that only the most relevant sources were included as samples. Data collection involved a thorough examination of the findings from these selected sources. …”
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6414
Realising health justice in Palestine: beyond humanitarian voices
Published 2025-02-01“…We also argue that the authors have failed to afford due recognition to several key health actors in Palestine, in particular the Palestinian Ministry of Health in Gaza and UNRWA, and that this subtle but critical act of erasure further undermines the relevance and applicability of their recovery proposal as presented. …”
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6415
Chemopreventative potential of Salsola tuberculatiformis Botch and Compound A in the differential regulation of IL-1Ra:IL-1α in UVB exposed skin keratinocytes
Published 2025-02-01“…These anti/pro-inflammatory effects may have potential relevance in wound healing. Compound A displayed a novel indirect anti-inflammatory effect by removing inflamed and damaged cells via apoptosis and ROS production. …”
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6416
The Croton genera (Euphorbiaceae) and its richness in chemical constituents with potential range of applications
Published 2025-02-01“…Conclusion: This revision has a novel and principal aim: to collect information on the biomedicinal, chemical, and industrial applications of extracts from several species distributed across various regions of the world (Africa, South America, Asia, North America, Central America, and South America), providing an objective evaluation of the relevance of the studies cited here and their suitability for scientific scrutiny and systematic reproduction of the results obtained . …”
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6417
LEGAL AND ECONOMIC PRINCIPLES OF THE FOREIGN POLICY OF INDEPENDENT AZERBAIJAN IN RELATION TO NEIGHBORING COUNTRIES
Published 2024-12-01“…Among the countries occupying a dominant position in the world economy, Azerbaijan has developed the deepest and broadest relations with China, which is reflected in the relevant foreign economic projects. The legal basis of Azerbaijan's co-operation with neighbouring countries is determined on three levels: 1) universal international law; 2) regional international law; 3) national. …”
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6418
Micro-Credit Institutions’ Services and Sustainability of Micro, Small and Medium-Scale Enterprises During Covid-19 Pandemic in Kigezi Region, South Western Uganda.
Published 2023“…The value of CVI obtained was 0.78 while the value of reliability obtained was 0.767, which indicates that the questionnaire items were relevant and suitable for the study. Three hundred and twelve (312) questionnaires were administered while a total of two hundred and ninety-four (294) MSMEs returned the filled questionnaires, giving the return rate as 94.2%. …”
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Technical Report -
6419
Free fatty acids may regulate the expression of 11β-hydroxysteroid dehydrogenase type 1 in the liver of high-fat diet golden hamsters through the ERS-CHOP-C/EBPα signaling pathway...
Published 2025-02-01“…Following an oral fat tolerance test (OFTT), blood lipids and FFA levels were measured. …”
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6420
Path model explaining the association between fear of falling and health-related quality of life in (pre-)frail older adults
Published 2025-02-01“…Pathways of minor individual relevance (e.g. through disability or affect) contributed considerably to the total indirect effect when combined. …”
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