Individualized resting-state functional connectivity abnormalities unveil two major depressive disorder subtypes with contrasting abnormal patterns of abnormality by Keke Fang, Lianjie Niu, Baohong Wen, Liang Liu, Ya Tian, Huiting Yang, Ying Hou, Shaoqiang Han, Xianfu Sun, Wenzhou Zhang

“…Subject-level extreme functional connections, determined by comparing against normative ranges derived from healthy controls using tolerance intervals, were used to identify biological subtypes of MDD. …”
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Exploring DNA methylation, telomere length, mitochondrial DNA, and immune function in patients with Long-COVID by Andrea Polli, Lode Godderis, Dries S. Martens, Madhura Shekhar Patil, Jolien Hendrix, Arne Wyns, Jente Van Campenhout, Emma Richter, Lara Fanning, Olivia Vandekerckhove, Eveline Claeys, Wim Janssens, Natalie Lorent

“…Cardiac involvement (as measured by troponin T levels) and telomere shortening might be a relevant risk factor for developing PEM-fatigue symptoms and deserve further exploring.…”
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Diagnosis and treatment of thyroblastoma: a case report and review of literature by Xiting Chen, Xiting Chen, Lijuan Xiong, Lijuan Xiong, Hongling Liu, Haoqiang Wang, Donghai Cheng, Wei Wang, Wenyuan He, Bo Xie, Juan Zhou

“…This classification was based on the observation that the tumor presents with independent primitive multilineage elements and is frequently associated with DICER1 hotspot mutations.The objective of this study was to explore and investigate the clinicopathologic characteristics, molecular features and treatment strategies of patients with thyroblastoma, followed by a review of the previous relevant literature.MethodsThe clinical manifestations, pathological characteristics, molecular features and treatment strategies of the initial case of thyroblastoma pathologically confirmed in China were analyzed.ResultsThe tumor was revealed to have high invasive potential, rapid disease progression, and primitive multilineage elements of pathology, including immature thyroid epithelium, spindled mesenchymal proliferations, and neuroepithelial blastema. …”
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Impoundments facilitate upstream invasion and introgression: Case studies of fluvial black basses (Micropterus spp.) in the southeastern USA. by Andrew T Taylor, Michael D Tringali, James M Long

“…Black basses (genus Micropterus) are popular sportfishes with divergent ecologies: some taxa are tolerant of impoundments and widely stocked to create fishing opportunities, whereas others are endemic fluvial specialists that are threatened by introgression with non-native congeneric taxa. …”
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Oridonin: A natural terpenoid having the potential to modulate apoptosis and survival signaling in cancer by Abhishek Chauhan, Hemant Joshi, Divya Kandari, Diwakar Aggarwal, Ritu Chauhan, Hardeep Singh Tuli, Arpit Mehrotra, Abhilasha Sood, Ujjawal Sharma, Darin Mansor Mathkor, Shafiul Haque, Naveen Chandra Joshi, Laurent Dufossé

“…Keywords such as ''Oridonin,'' ''Apoptosis,'' ''Cancer Cell Signaling Pathways,'' ''PI3K/AKT,'' ''ROS,'' and ''Nanotechnology'' were used, yielding 96 relevant studies. Results: Oridonin induces apoptosis through intrinsic and extrinsic pathways, involving ROS amplification and mitochondrial membrane potential regulation. …”
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Very first real-world data on zongertinib use in non-small cell lung cancer patients with HER2 mutations: A brief report by Oliver Illini, Anna Sophie Lang-Stöberl, Hannah Fabikan, Christoph Weinlinger, Arschang Valipour, Maximilian J. Hochmair

“…Conclusion: Zongertinib may be an effective and well-tolerated treatment option for HER2-mutant NSCLC patients even if they are heavily pretreated, have a reduced performance status or have a history of pneumonitis and brain metastases.…”
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Efficacy and safety of once-weekly semaglutide monotherapy in a young subject with Prader-Willi syndrome, obesity, and type 2 diabetes: a case report by Elisa Dinoi, Giuseppe Daniele, Giuseppe Daniele, Angela Michelucci, Fulvia Baldinotti, Fabrizio Campi, Piero Marchetti, Stefano Del Prato, Angela Dardano, Angela Dardano

“…Ad hoc trials are needed to evaluate the long-term efficacy and tolerability in these subjects.…”
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Clinical Consultation in the Workplace: Are There Implications for Response Attitudes? by Bárbara Gonzalez, Rosa F. Novo, Maria João Afonso, Matilde Fernandes, Ana Vieira

“…In conclusion, there are relevant differences in response attitude and psychopathology features between outpatients assessed in a traditional clinical setting and in a clinical-organizational one, suggesting the professional context of the patients may influence motivations to disclosure psychological symptoms and problems.…”
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Effects of non-contact electric fields on the kidneys and livers of tumour-bearing rats [version 6; peer review: 1 approved, 2 approved with reservations, 1 not approved] by Luthfi Nurhidayat, Ahmad Ghitha Fadhlurrahman, Firman Alamsyah, Warsito Purwo Taruno, Nisrina Firdausi, Subekti Evi Dwi Nugraheni, Rarastoeti Pratiwi

“…However, in kidney tissue, exposure to this electric field was tolerable, and can even decrease the number of inflammations and haemorrhages in healthy rats.…”
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Design of a Mechanized Road Sweeper by Asiimwe Dianah

“…The major components of the proposed machine were drive wheels, gears, sweeping roller and disc brushes, dust filter, waste container, handle and frame. …”
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Aberrant SNHG expression predicts poor prognosis in esophageal cancer using meta-analysis and bioinformatics analysis by Ke Shi, Li-De Huang, Dan Li, Wei-Min Luo, Hua-Song Liu, Dong-Xiao Ding, Qiang Guo, Yue-Feng Liu

“…A meta-analysis was performed to investigate the relationship between SNHG expression and prognosis of EC in this study. Methods Relevant databases were browsed to obtain suitable publications. …”
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The Impact of Stock Liquidity on Returns under Asymmetric Information and Financial Constraints by Mehrzad Alijani, Fatemeh Nezhad Hossseinian

“…The outcomes of this research carry relevance for the Tehran Stock Exchange, investment firms, and brokerage companies. …”
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Realist inquiry into Maternity care @ a Distance (ARM@DA): realist review protocol by Andrew Booth, Catrin Evans, Stephen Timmons, Helen Spiby, Mark Clowes, Nia Jones, Kerry Evans, Benash Nazmeen, Candice Sunney, Georgia Clancy

“…Findings will be disseminated in a range of formats relevant to different audiences.PROSPERO registration number CRD42021288702.…”
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DIGITISATION OF LEGAL ALGORITHMS TO PREVENT PUBLIC PROCUREMENT CORRUPTION by Oleksii Makarenkov

“…In order to accomplish this, said entity requires full legal access to the necessary data from registries and other relevant sources. At present, this is only feasible within the framework of criminal proceedings and/or judicial processes. …”
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Risk prediction models for stress urinary incontinence after pelvic organ prolapse (POP) surgery: a systematic review and meta-analysis by Bi Jun Yu, Hao Chong He, Li Wang, Han Mei Shao, Ying Min Liu, Xiao Ying Yan, Jian Liu

“…Abstract Objective To systematically evaluate existing developed and validated predictive models for stress urinary incontinence after pelvic floor reconstruction. Methods Relevant literature in PubMed, Embase, Web of Science, Cochrane Library, OVID, China National Knowledge Infrastructure(CNKI), Wan Fang Database, VIP database and Chinese Biomedical Literature Service System (SinoMed) were search from inception to 1 March 2024. …”
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Epidemiology of clinically significant migraine in Israel: a retrospective database study by A. Shifrin, E. Domany, M. Tirosh, D. Davidovici, S. Vinker, I. Forschner, A. Israel

“…Additionally, we compared relevant characteristics between adult migraine and non-migraine members of Leumit Healthcare Services (LHS), a national health provider in Israel. …”
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Characterization of Vaginitis Among Women Complaining of Genital Tract Symptoms by Hemin Muheddin Kareem, Muhammed Saed Qadir, Safa Bakr Karim, Solaf Jawhar Ali

“…Samples were examined microbiologically and causative agents were isolated. All relevant clinical information such as patient demographic profiles, socioeconomic variables, risk factors and symptoms have been collected by questionnaire based study. …”
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Assessing routine childhood vaccination acceptance, hesitancy and refusal in Cape Town, Western Cape, South Africa: a mixed-method study protocol by Charles Shey Wiysonge, Lindi Mathebula, Moleen Zunza, Sara Cooper

“…Findings of the study will be shared with various healthcare stakeholders through conferences and presentations at relevant meetings.Conclusion Evidence from several studies conducted in South Africa shows a significant increase in vaccine hesitancy within the country. …”
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Satellite-based Emission Inventory Adjustments Improve Simulations of Long-range Transport Events by Wei-Syun Huang, Stephen M. Griffith, Yi-Chun Lin, Ying-Chieh Chen, Chung-Te Lee, Charles C.-K. Chou, Ming-Tung Chuang, Sheng-Hsiang Wang, Neng-Huei Lin

“…Adjustment of an emissions inventory based on satellite measurements during the COVID-19 lockdown in China led to a ~59% reduction in emissions over the relevant source area in China compared to base emissions. …”
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The Association of Retinal Disease with Vision Impairment and Functional Status in Medicare Patients by Vincent Garmo, Xiaohui Zhao, Carmen D. Ng, Aimee Near, Tania Banerji, Keiko Wada, Gary Oderda, Diana Brixner, Joseph Biskupiak, Ferhina S. Ali, Archad M. Khanani, Alicia Menezes, Ibrahim M. Abbass

“…After adjusting for age, sex, race/ethnicity, poverty status, comorbidities, and other relevant covariates, nAMD, DME, and RVO were not significantly associated with anxiety/depression, falls, or fractures. …”
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