Modeling of drying kinetics and chemical analysis for optimal preservation of pitahaya, aguaymanto and pineapple fruits using a parabolic solar dehydrator in the Amazon region - Pe... by Merbelita Yalta Chappa, Wildor Gosgot Angeles, Luz Quispe-Sanchez, Diana Carina Mori Servan, Homar Santillan Gomez, Manuel Oliva-Cruz, Miguel Ángel Barrena Gurbillón

“…The results revealed that the Midilli model fitted best for pitahaya (R2 = 0.9995, EF = 0.999) and aguaymanto (R2 = 0.9965, EF = 0.993); however, for pineapple slices, the most relevant model was Weibull (R2 = 0.9998, EF = 0.999). …”
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Overcoming hypoxia-induced breast cancer drug resistance: a novel strategy using hollow gold-platinum bimetallic nanoshells by Lian-Ying Zhang, Xiao-Tong Chen, Rong-Tian Li, Wei Meng, Guo-Qin Huang, Yong-Jian Chen, Feng-Jun Ge, Qun Zhang, Yu-Jun Quan, Cai-Tao Zhang, Yi-Fei Liu, Ming Chen, Jin-Xiang Chen

“…In this study, we present a strategy to overcome hypoxia-induced chemotherapy tolerance in BC. Specifically, we synthesized a hollow gold (Au)-platinum (Pt) bimetallic nanoshell for the first time, which acted as a drug delivery system (DDS) for doxorubicin (DOX). …”
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Dimorphos’s Material Properties and Estimates of Crater Size from the DART Impact by Angela M. Stickle, Kathryn M. Kumamoto, Dawn M. Graninger, Mallory E. DeCoster, Wendy K. Caldwell, Jason M. Pearl, J. Michael Owen, Olivier Barnouin, Gareth S. Collins, R. Terik Daly, Isabel Herreros, Jens Ormö, Jessica Sunshine, Carolyn M. Ernst, Toshi Hirabayashi, Simone Marchi, Laura Parro, Harrison Agrusa, Megan Bruck Syal, Nancy L. Chabot, Andy F. Cheng, Thomas M. Davison, Elisabetta Dotto, Eugene G. Fahenstock, Fabio Ferrari, Martin Jutzi, Alice Lucchetti, Robert Luther, Nilanjan Mitra, Maurizio Pajola, Sabina Raducan, KT Ramesh, Andrew S. Rivkin, Alessandro Rossi, Paul Sánchez, Stephen R. Schwartz, Stefania Soldini, Jordan K. Steckloff, Filippo Tusberti, Kai Wünnemann, Yun Zhang

“…Approach observations and those following the DART impact have provided crucial knowledge that narrows the parameter space relevant to modeling the impact into Dimorphos. Here we present the results of a suite of hydrocode simulations of the DART impact on Dimorphos. …”
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Examining reliability of WHOBARS: a tool to measure the quality of administration of WHO surgical safety checklist using generalisability theory with surgical teams from three New... by Jennifer M Weller, Carmen Skilton, Derryn A Gargiulo, Oleg N Medvedev, Simon J Mitchell, Alan F Merry

“…In this context, extending reliability refers to establishing generalisability of the tool scores across populations of teams and raters by accounting for the relevant sources of measurement errors.Design Cross-sectional random effect measurement design assessing surgical teams by the five items on the three Checklist phases, and at three sites by two trained raters simultaneously.Setting The data were collected in three tertiary hospitals in Auckland, New Zealand in 2016 and included 60 teams observed in 60 different cases with an equal number of teams (n=20) per site. …”
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Perceived urban environment elements associated with momentary and long-term well-being: An experience sampling method approach by Yu-Ru Chen, Atsushi Nakagomi, Masamichi Hanazato, Noriyuki Abe, Kazushige Ide, Katsunori Kondo

“…LWB was positively associated with MWB (standardized coefficient=0.24) and urban elements—cafés/restaurants/bars (0.11), cultural/sports/education facilities (0.04), and public spaces (0.11). Meanwhile, relaxing/clean (0.56) and natural environments (0.14) were associated with higher MWB. …”
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Ex vivo delivery of recombinant IL-10 to human donor lungs by Jonathan C. Yeung, Terumoto Koike, Dirk Wagnetz, Tiago N. Machuca, Riccardo Bonato, Mingyao Liu, Stephen Juvet, Marcelo Cypel, Shaf Keshavjee

“…Thus, we hypothesized that delivery of recombinant IL-10 (rIL-10) to injured donor lungs isolated on EVLP could be a clinically relevant and a logistically simpler method of employing IL-10 therapy in lung transplantation. …”
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Investigation of factors that affect post-fire recovery of photosynthetic activity at global scale by Yicheng Shen, I. Colin Prentice, Sandy P. Harrison

“…We then examined the factors that influence post-fire recovery time, initially using the relaxed lasso technique to identify the most important factors and then using a linear regression model incorporating these factors. …”
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Automatic Segmentation of Abdominal Aortic Aneurysm From Computed Tomography Angiography Using a Patch-Based Dilated UNet Model by Merjulah Roby, Juan C. Restrepo, Haehwan Park, Satish C. Muluk, Mark K. Eskandari, Seungik Baek, Ender A. Finol

“…Abdominal Aortic Aneurysm (AAA) is still a socially relevant public health challenge, evidenced by an 82.1% increase in associated fatalities from 1990 to 2019 (with 172,427 deaths in 2019 alone). …”
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Preferences of melanoma patients to accept adjuvant therapy and toxicity – a qualitative substudy of the GerMelaTox-A project by Toni Maria Janke, Laura Moysig, Christine Blome, Katharina C. Kähler

“…Therefore, this study investigates the motives of melanoma patients for tolerating or rejecting adjuvant therapy and its side effects. …”
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DEVELOPMENT OF MEDIA LITERACY AND COMMUNICATION SKILLS BY MEANS OF DIGITAL STORYTELLING IN JAPAN by Lyubov V. Gutor, Pavlo A. Sodomora, Oleh H. Vasylenko, Halyna I. Zalutska

“…DST can improve physician-patient communication skills, professional qualities, tolerance and empathy. Our research confirms the potential of DST as a powerful developmental tool of media literacy and oral communication skills, and proves the requirement for the implementation of Japanese experience into higher education of Ukraine. …”
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Predicting the risk of cardiovascular disease in adults exposed to heavy metals: Interpretable machine learning by Meiyue Shen, Yine Zhang, Runqing Zhan, Tingwei Du, Peixuan Shen, Xiaochuan Lu, Shengnan Liu, Rongrong Guo, Xiaoli Shen

“…The Least Absolute Shrinkage and Selection Operator regression method was employed to select relevant feature variables. Subsequently, six machine learning models were constructed, including random forest, decision tree, gradient boosting decision tree, k-nearest neighbor, support vector machine, and AdaBoost algorithms. …”
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Did selective kinase inhibitors change the management of patients with radioiodine-refractory thyroid cancer? by Tommaso Porcelli, Cristina Luongo, Anna Cerbone, Carmine Di Luccio, Mariantonia Nacchio, Maria Angela De Stefano, Martin Schlumberger, Domenico Salvatore

“…Conclusion: S-TKIs permitted tailoring systemic treatment based on disease location, tumour volume and patient comorbidities, achieving satisfactory tolerance and outcomes in selected patients with an actionable driver mutation and with contraindications to angiogenesis inhibitors or candidates for redifferentiation therapy.…”
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Humanising nanotoxicology: replacement of animal-derived products in the application of integrated approaches to testing and assessment of nanomaterial inhalation hazard by Roma Fraser, Keira Campbell, Pawel Pokorski, Eve MacKinnon, Katie McAllister, Karla B. Neves, Fiona Murphy

“…Incorporating human or synthetic alternatives can significantly reduce the ethical burden of animal use while enhancing the relevance of toxicity testing. This study evaluates the impact of removing animal-derived products from standard acellular and in vitro assays recommended in a published Integrated Approaches to Testing and Assessment (IATA) for inhaled NMs. …”
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Additive-manufactured ceramics for dental restorations: a systematic review on mechanical perspective by Yuqing Lu, Anouk van Steenoven, Amanda Maria de Oliveira Dal Piva, João Paulo Mendes Tribst, Li Wang, Li Wang, Cornelis J. Kleverlaan, Albert J. Feilzer, Albert J. Feilzer

“…Published articles from 2019 to 2023 were screened, analysed and the relevant papers were selected for inclusion in this review.ResultsA total of 40 studies were included. …”
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ZBiotics ameliorates T2DM-induced histopathological damage in liver, kidney and adipose tissues by modulating the NOD-like receptor signaling in Wistar rats by Mohammed Esawie, Marwa Matboli, Mariam Sameh Bushra, Amany H. Hasanin, Eman Kamal Habib, Reham Hussein Mohamed, Hebatalla Said Ali

“…At the biochemical aspect, ZBiotics corrected LDL-c and improved serum creatinine and CK-MB levels. Inflammation relevant genes have been downregulated regarding CHUK, NFKB1 and miR-611. …”
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Tritordeum, barley landraces and ear photosynthesis are key players in cereal resilience under future extreme drought conditions by Ander Yoldi-Achalandabaso, Aitor Agirresarobe, Artūrs Katamadze, Giulia Burini, Omar Vergara-Díaz, Mariana Mota, Cristina Oliveira, Usue Pérez-López, Rubén Vicente

“…Our study aimed to identify key functional traits and stress-tolerant germplasm to contribute to designing drought-resilient crops under future Mediterranean climatic conditions. …”
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Spatial heterogeneity in deployment and upscaling of wind power in Swedish municipalities by Yodefia Rahmad, Fredrik Hedenus, Jessica Jewell, Vadim Vinichenko

“…First, techno-economic, socio-technical, and political perspectives from national energy transition literature were employed to identify relevant deployment mechanisms. Second, the approach differentiated between small-scale and large-scale wind power to avoid conflating results from obsolete technologies. …”
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Crimean-Congo haemorrhagic fever virus screening among African individuals in Spain: Lessons to learn by Helena Miriam Lorenzo Juanes, Amparo López-Bernus, Belen Vicente, Montserrat Alonso-Sardón, Beatriz Rodríguez Alonso, Josue Pendones Ulerio, Pedro Fernandez Soto, Juan Luis Muñoz Bellido, Antonio Muro, Moncef Belhassen-García

“…Our results suggest the need for more extensive clinical and epidemiological studies in Africans to determine the epidemiology and transmission of CCHFV in Spain and to evaluate the relevance of control measures for clinical interventions in situations with a potential risk of transmission. …”
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Efficient biosynthesis of β-caryophyllene by engineered Yarrowia lipolytica by Young-Kyoung Park, Lucie Studena, Piotr Hapeta, Ramdane Haddouche, David J. Bell, Pablo Torres-Montero, Jose Luis Martinez, Jean-Marc Nicaud, Adriana Botes, Rodrigo Ledesma-Amaro

“…This strategy suggests its potential extension to studies involving the microbial production of various industrially relevant terpenes.…”
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‘It takes a village’: patient lived experiences of residential treatment for an eating disorder by Rebekah Rankin, Janet Conti, Lucie Ramjan, Phillipa Hay

“…Data were analysed with inductive reflexive thematic analysis. Results Three main themes were generated from the data that included participants’ journeys to treatment, experiences of treatment and the transitions associated with and following discharge. …”
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