Association of expedited review programmes with postmarketing safety events of new drugs approved by the US food and drug administration between 2007 and 2017 by Bao Liu, Xingyue Zhu

“…Objective To explore the associations between the risks of postmarketing safety events of new drugs and the four expedited programmes of priority review, accelerated approval, fast track and breakthrough therapy established by the US Food and Drug Administration (FDA); and to investigate whether multiple uses of expedited programmes, and the combinations of expedited programmes with orphan designation, were relevant to different safety profiles.Design Cohort study.Setting USA.Participants All new drugs approved by the FDA between 1 January 2007 and 31 December 2017, followed up until 10 April 2021.Outcome measures Safety events included safety-related withdrawal, new boxed warning, drug safety communication, postapproval risk evaluation mitigation strategy and safety-related labelling changes. …”
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ANALYSIS OF THE RESULTS OF SIMULATIVE MODELLING OF THE INFORMATION SECURITY SYSTEM IN THE CORPORATE NETWORKS OF HIGHER EDUCATION INSTITUTIONS by Vagif Gasimov, Balami Ismailov

“…This shows that this problem has not yet been sufficiently studied and relevant. This work is one of the steps towards creating a system for assessing information security in service networks. …”
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Chemical reaction and Soret impacts on MHD heat and mass transfer Casson hybrid nanofluid (MoS2+ZnO) flow based on engine oil across a stretching sheet with radiation by M. Radhika, Y. Dharmendar Reddy

“…The primary objective of investigating the hybrid nano lubricant MoS2 + ZnO combined with engine oil is to further the development of more durable and efficient lubrication solutions for automotive engines, hence improving reliability, fuel efficiency, and environmental sustainability. The relevant similarity variables convert the governing nonlinear partial differential equations to ordinary differential equations (ODEs). …”
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The impact of smartphone addiction on exercise patterns: a systematic review by Siti Kotijah, Ah Yusuf, Rizki Fitryasari P K, Ronal Surya Aditya, Binarti Dwi Wahyuni, Reem Iafi AlMutairi, Fitriana Kurniasari Solikhah, Muhammad Putra Ramadhan

“…Databases such as PubMed, Google Scholar, Scopus, Web of Science, and PsycINFO were searched using relevant keywords. Included studies were randomized controlled trials, cohort studies, longitudinal studies, and cross-sectional studies. …”
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Single inhaler with beclometasone, formoterol, and glycopyrronium versus triple therapies in adults with uncontrolled asthma: a systematic review and meta-analysis by Fulvio Braido, Ioanna Vlachaki, Georgios F. Nikolaidis, Dimitrios Tzelis, Ifigeneia Barouma, Alessio Piraino, Alessandra Madoni, Nicola Scichilone

“…HD BDP/FOR/GLY and HD BDP/FOR + tiotropium did not differ significantly. Compared to relevant single-inhaler triple therapies, MD and HD BDP/FOR/GLY are associated with a significant benefit or trend for improvement in terms of reducing the rate of severe and moderate-to-severe exacerbations.…”
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Use of wearable technology in cardiac monitoring after cryptogenic stroke or embolic stroke of undetermined source: a systematic review by Jamie SY Ho, Elizabeth SY Ho, Leonard LL Yeo, William KF Kong, Tony YW Li, Benjamin YQ Tan, Mark Y Chan, Vijay K Sharma, Kian-Keong Poh, Ching-Hui Sia

“…Results: A total of 27 relevant studies were included (two randomised controlled trials, seven prospective trials, 10 cohort studies, six case series and two case reports). …”
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The impacts of antipsychotic medications on eating-related outcomes: A mixed methods systematic review. by Rasha Alkholy, Karina Lovell, Penny Bee, Rebecca Pedley, Helen Louise Brooks, Richard J Drake, Prathiba Chitsabesan, Anam Bhutta, Abigail Brown, Rebecca L Jenkins, Andrew Grundy

“…Lived experience perspectives were incorporated in different stages of the review to enhance its relevance and practical implications.<h4>Conclusions</h4>There is insufficient evidence from well-conducted studies to determine the effect of antipsychotics on eating-related outcomes.…”
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The Taking Charge After Stroke (TaCAS) study protocol: a multicentre, investigator-blinded, randomised controlled trial comparing the effect of a single Take Charge session, two Ta... by Mark Weatherall, Harry McNaughton, Vivian Wai Yin Fu

“…Results will be published and presented at relevant stroke meetings within New Zealand and internationally, informing the use of a self-management intervention after stroke.Trial registration Australia and New Zealand Clinical Trials Registry ACTRN12615001163594. …”
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Effect of noninvasive respiratory support on interstitial lung disease with acute respiratory failure: A systematic review and meta-analysis by Natthawan Sanguanwong, Nattawat Jantarangsi, Jinjuta Ngeyvijit, Natthida Owattanapanich, Vorakamol Phoophiboon

“…An additional search of relevant primary literature and review articles was also performed. …”
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SELECTION OF DIGITAL TOOLS FOR ORGANIZING STUDENTS' GROUP WORK IN DISTANCE EDUCATION by Olena G. Glazunova, Andrii M. Hurzhii, Valentyna I. Korolchuk, Tetiana V. Voloshyna

“… The transformation of classical education into distance education has become increasingly relevant, especially given the challenging conditions posed by the COVID-19 pandemic and military operations in our country. …”
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Sternal-Wound Infections following Coronary Artery Bypass Graft: Could Implementing Value-Based Purchasing be Beneficial? by Dominique Brandt, Maximilian Blüher, Julie Lankiewicz, Peter J. Mallow, Rhodri Saunders

“…**Methods:** A structured literature review identified relevant data for 14 countries (the Netherlands, France, Germany, Austria, the United Kingdom, Canada, Italy, Japan, Spain, the United States, Brazil, Israel, Taiwan, and Thailand). …”
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Efficient Feature Selection and Hyperparameter Tuning for Improved Speech Signal-Based Parkinson’s Disease Diagnosis via Machine Learning Techniques by Deepak Painuli, Suyash Bhardwaj, Utku Kose

“…To enhance model performance, the GridSearchCV method was employed for hyperparameter tuning, alongside recursive feature elimination (RFE) and minimum redundancy maximum relevance (mRMR) feature selection techniques. Among the 12 ML models evaluated, the RF model with the RFE-generated feature subset (RFE-50) emerged as the top performer. …”
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Military personnel’s satisfaction with antiretroviral services in Namibia: A cross-sectional study by Nestor P.N. Tomas, Nabot P. Kandjimi

“…Background: Patient satisfaction is an indicator of healthcare quality and may affect treatment adherence. It is particularly relevant for military personnel living with human immunodeficiency virus (HIV) because of their increased risks to deployment. …”
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A systematic review on concentration of residential indoor air metals and health risk assessment by Ali Momen, Arezo Rezaie, Roohollah Rostami

“…We conducted a comprehensive literature search across Google Scholar, ScienceDirect, and SpringerLink, identifying 34 relevant studies measuring metal concentrations in various residential environments. …”
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Risk factors for emergency presentation with lung and colorectal cancers: a systematic review by Una MacLeod, Elizabeth D Mitchell, Benjamin Pickwell-Smith

“…No conclusive evidence was found.Conclusions Patient-related factors, such as age, gender and deprivation, increase the likelihood of cancer being diagnosed as the result of an EP, while cancer symptoms and patterns of healthcare utilisation are also relevant. Further work is needed to understand the context in which risk factors for EP exist and influence help-seeking.…”
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Assessment of air pollutants when burning alternative fuels by Olena Levytska, Artem Sikorsky

“…The comparative characteristics of alternative and traditional fuels are relevant due to the exhaustibility of traditional fuels. …”
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Can physical and psychological factors predict pain recurrence or an exacerbation of persistent non-specific low back pain? A protocol for a systematic review and meta-analysis by Deborah Falla, Michael Mansfield, Janet Deane, Kanya Wongwitwichote, Cho Wai Geoffrey Yu

“…The findings from the systematic review will be submitted for publication in a peer-reviewed journal and will also be presented at relevant conferences.PROSPERO registration number CRD42024599514.…”
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A qualitative analysis of Arabic language websites about extraction of third molars by Muath Saad Alassaf, Mohannad Mohammed Abu Aof, Osama Ayidh Alharbi, Abdulrahman Turkustani, Moataz Ibrahim Karbouji, Nebras Althagafi, Ahmed Mohammed Almghamsi, Ghayda Yousof Zolaly, Shadia Elsayed

“…Conclusion the study results indicating a broad spectrum in the explicitness and relevance of information with moderate quality across the evaluated websites and the investigation revealed significant variations in the content quality and readability provided by websites belonging to various affiliations, with non-profit websites generally achieving higher scores in JAMA criteria and readability measures.…”
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A Systematic Literature Review and Bucher Indirect Comparison: Tildrakizumab versus Guselkumab by Kristian Garn Du Jardin, Pepi Hurtado Lopez, Mette Lange, Rachael McCool, Silvia Maeso Naval, Sandra Quickert

“…Limitations included the limited number of publications, imputation of placebo arm values for Weeks 24 to 28, and limited relevance of the Japanese study. This indirect comparison does not provide evidence that one treatment is superior to the other.…”
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Effectiveness of a novel amine + zinc + fluoride toothpaste in reducing plaque and gingivitis: results of a six-month randomized controlled trial by Dutmanee Seriwatanachai, Terdphong Triratana, Petcharat Kraivaphan, Norbert Huber, Tilo Poth, Luis R. Mateo, Melissa Stellitano, Yun-Po Zhang

“…Conclusions The amine + zinc + fluoride toothpaste significantly improved measures of plaque (12× more effective) and gingivitis (5× more effective) in comparison to a standard fluoride toothpaste, suggesting that the novel formulation with antibacterial active ingredients amine and zinc facilitates more effective plaque removal, and promotes gingival health. Clinical relevance These results suggest that daily use of amine + zinc + fluoride toothpaste can provide a significant improvement in managing plaque accumulation and bleeding associated with gingival inflammation especially for patients experiencing gingivitis. …”
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