The effect of blue-blocking intraocular lenses on circadian biological rhythm: protocol for a randomised controlled trial (CLOCK-IOL colour study) by Taiji Hasegawa, Kenji Obayashi, Kimie Miyata, Tetsuo Ueda, Norio Kurumatani, Keigo Saeki, Nahoko Ogata, Hiroki Tsujinaka, Mariko Yamashita, Tomo Nishi, Nobuhiro Tone, Naonori Masuda, Yutarou Mizusawa, Masahiro Okamoto, Shinji Maruoka, Masashi Kojima, Toyoaki Matsuura

“…Introduction Blue light information plays an important role in synchronising internal biological rhythm within the external environment. …”
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InfectA-Chat, an Arabic Large Language Model for Infectious Diseases: Comparative Analysis by Yesim Selcuk, Eunhui Kim, Insung Ahn

“…In this regard, regular monitoring activities play a crucial role in mitigating the adverse effects of diseases on society. …”
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Machine Learning Diagnostic Model for Hepatocellular Carcinoma Based on Liquid–Liquid Phase Separation and Ferroptosis-Related Genes by Wenchao Chen, Ting Zhu, Xiaofan Pu, Linlin Zhao, Senhao Zhou, Xin Zhong, Suihan Wang, Tianyu Lin

“…The interplay between liquid–liquid phase separation (LLPS) and ferroptosis—a regulated form of cell death—has garnered interest in tumorigenesis. However, the precise role of LLPS and ferroptosis-related genes in HCC progression and prognosis remains obscure. …”
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Multiparameter resting-state functional magnetic resonance imaging as an indicator of neuropsychological changes in Binswanger’s disease with mild cognitive impairment by Haiyi Zhang, Lu Zhang, Juan Lu, Jiajun Yue, Zhengzhen Yuan, Jidan Hu, Qi Yao, Yuting Fu, Guiquan Chen, Jiliang Fang, Jie Zhao

“…The reduced coordination among these functional networks may play a role in the deterioration of cognitive functions and decision-making capabilities, potentially serving as a critical mechanism contributing to the early manifestation of cognitive impairments.…”
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Provincial distribution and predictors of desire for more children among married and cohabiting women in Sierra Leone by Augustus Osborne

“…The association between contraceptive use and lower fertility desires underscores the role of access to and education about contraception in shaping family planning decisions. …”
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Transcriptomic and behavioral studies reveal that glutamate receptors are involved in depressive-like behavior in adult olive flounder Paralichthys olivaceus by Liangfang Liu, Tangsong Feng, Mengmeng Shi, Huafeng Zou, Weiqun Lu

“…Taken together, in combination with behavioral tests and transcriptomic analyses, we conclude that the glutamate receptor in spinal cord plays an important role in timid and depressive-like behavior in flounder.…”
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FUNCTIONS OF THE STATE AND LOCAL SELF-GOVERNMENT BODIES IN THE REGULATION OF FUNERAL SERVICES: ECONOMIC ASPECTS AND ENSURING SOCIAL STANDARDS by Denys Komarnytskyi, Liudmyla Sylenko, Roman Tуtykalo

“…The article examines the role of the state and local authorities in regulating the funeral industry, focusing on their functions and tasks. …”
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Fucosylated haptoglobin promotes inflammation via Mincle in sepsis: an observational study by Taylor Roh, Sungeun Ju, So Young Park, Yeonghwan Ahn, Jiyun Chung, Miyako Nakano, Gyoungah Ryu, Young Jae Kim, Geumseo Kim, Hyewon Choi, Sung-Gwon Lee, In Soo Kim, Song-I Lee, Chaeuk Chung, Takashi Shimizu, Eiji Miyoshi, Sung-Soo Jung, Chungoo Park, Sho Yamasaki, Seung-Yeol Park, Eun-Kyeong Jo

“…Together, our findings reveal a role of Fu-Hp, derived from sepsis patients, in driving inflammation, and suggest that targeting Fu-Hp could serve as a promising intervention for combating sepsis. …”
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The Relationship Between Serum 25 hydroxy Vitamin D Deficiency and Dietary Pattern in Baxshin Hospital, Sulaimani City by Mohammed I M Gubari, Jeza Muhamad Abdul Aziz, Fadhil Ahmed Mohialdeen, Khalid Anwar Hama-Ghareeb, Bakhtyar Kamal Muhamed, Hemn Abdalla Omer

“…Vitamin D is one of the fat-soluble vitamins that have a great role in phosphate and calcium balance and bone structure. …”
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Dimethyl fumarate promotes the degradation of HNF1B and suppresses the progression of clear cell renal cell carcinoma by Yue Dai, Hongchen Li, Shiyin Fan, Kai Wang, Ziyi Cui, Xinyu Zhao, Xue Sun, Mingen Lin, Jiaxi Li, Yi Gao, Ziyin Tian, Hui Yang, Bingbing Zha, Lei Lv, Yanping Xu

“…In summary, we provide evidences supporting DMF as a potential drug for clinical treatment of ccRCC by targeting HNF1B and reveal a previously unrecognized role of HNF1B in regulating YAP in ccRCC.…”
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Combination of mentor-based and resident-based learning may benefit to improving the ability of clinical practice in resident training by Min Li, Tao Liu, Yiqiong Wen, Min Zhang, Wenye Zhu, Xuming Wang, Yunjiao Hou, Lin Li, Anju Zu, Shibo Sun

“…This study proposed the combination of mentor-based and resident-based learning (CMRL) and explored the role of CMRL in improving the effect of medical resident training. …”
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Presenting a Model for Color Effectiveness in Marketing Using Consumer Neuroscience: A Sequential Exploratory Mixed-Methods Approach by Allahyar Ghasemi, Ahmad Rahchamani, Hamidreza Saeednia

“…We should keep in mind that organizational and advertising colors have cognitive and emotional impacts on the contacts of the organization and the correct selection of these visual elements plays an important role in creating brand awareness.…”
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Molecular characterization of pregnancy-associated breast cancer and insights on timing from GEICAM-EMBARCAM study by Regina Peña-Enríquez, Begoña Bermejo, Marina Pollán, Alejandra Díaz-Chacón, Yolanda Jerez Gilarranz, José J Ponce Lorenzo, Antonio Fernández Aramburo, Blanca Cantos Sánchez de Ibargüen, Ana Santaballa Bertrán, Elena Galve-Calvo, Álvaro Jiménez-Arranz, Yolanda Fernández, María Eva Pérez, Susana De La Cruz, Antonio Anton-Torres, Fernando Moreno, María Jesús Vidal-Losada, María Helena López-Ceballos, Isabel Blancas, María José Echarri, Raúl Rincón, Rosalía Caballero, Ángel Guerrero-Zotano, Silvia Guil-Luna, Juan de la Haba-Rodríguez

“…These findings suggest an enhanced proliferative capacity and impaired DNA repair in PABC, and underscore the role of immune infiltration in postpartum cases; providing insights into its aggressive nature and potential targets.…”
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Nonylphenol exposure increases the risk of Hirschsprung’s disease by inducing macrophage M1 polarization by Xuefeng Yang, Chengyan Tang, Daiwei Zhu, Xingrong Xia, Qing Du, Lu Huang, Jianguo Liu, Yuanmei Liu

“…Herein, we identified the content of NP and expression of lncRNA LINC00294/Inhibin Subunit Beta E (INHBE) axis in clinical samples and evaluated the crucial role of lncRNA LINC00294/INHBE axis in the neurogenic potential of neurons and the neurotoxicity effects of NP in the SH-SY5Y cells and female specific pathogen-free (SPF) rat model. …”
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Characterization of the genomic landscape of canine diffuse large B-cell lymphoma reveals recurrent H3K27M mutations linked to progression-free survival by Anna Darlene van der Heiden, Raphaela Pensch, Sophie Agger, Heather L. Gardner, William Hendricks, Victoria Zismann, Shukmei Wong, Natalia Briones, Bryce Turner, Karin Forsberg-Nilsson, Cheryl London, Kerstin Lindblad-Toh, Maja Louise Arendt

“…These findings underscore the critical role of epigenetic dysregulation in cDLBCL and affirm the dog as a relevant large animal model for interrogating the biological activity of novel histone-modifying treatment strategies.…”
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Implementasi Model Design Thinking pada Prototype Aplikasi E-Growth by Debi Setiawan, Ramalia Noratama Putri, Ira Puspita Sari

“…Abstract The rapid development of technology has many influences on the human side of life. The role of this technological development can help improve the quality of health in Indonesia, one of which is in recording child development stored on smartphones. …”
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High concentrations of polyethylene microplastics restrain the growth of Cinnamomum camphora seedling by reducing soil water holding capacity by Run Yang, Jinping Wang, Huanying Fang, Jinwen Xia, Guomin Huang, Rongzhen Huang, Hong Zhang, Liqin Zhu, Lichao Zhang, Jihong Yuan

“…However, few studies have been conducted on woody plants that play a prominent role in ecosystems, while crucial edaphic factors which potentially restrain plant growth in MP-contaminated soils are yet to be revealed. …”
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Integrating Bulk and Single-Cell Transcriptomic Data to Identify Ferroptosis-Associated Inflammatory Gene in Alzheimer’s Disease by Zhou H, Peng Y, Huo X, Li B, Liu H, Wang J, Zhang G

“…Cell experiments confirmed that SLC11A1 was significantly upregulated in inflammatory microglia induced by ferroptosis.Conclusion: This study reveals the key role of SLC11A1 in AD, particularly in the context of ferroptosis and immune inflammation. …”
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Call to Action: Lead Pharmacy into the Next Decade by Kerry K Fierke, Gardner Lepp, Bridget McGugan, Marta Brooks, Gregory Zumach

“… • Ross-Hellauer, Tony, et al. "Ten simple rules for innovative dissemination of research." …”
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Development of an Integrated Model of Planning and Management in Free Zones with an Emphasis on Environmental Pressures by Mohammad Javad Amiri, Vahid Moghaddamzadeh, Gholamreza Nabi Bidhendi

“…Goal: The Aras Free Zone, positioned in the northwest of Iran, serves as a critical conduit to the Caucasus region and Eastern Europe, thereby holding a pivotal role in fostering economic relations. This research is dedicated to the comprehensive management of the cities within the Aras Azad region, emphasizing a balanced approach to environmental management that encompasses the natural, human, and physical dimensions. …”
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