Shaping the future of primary healthcare: Factors influencing medical students’ preference for family medicine specialty in Qatar by Maryam A. Al-Rashid, Muna T Abed Alah, Areej S. Al-Hamad, Michail Nomikos, Marwan F. Abu Hijleh

“…Information sought included sociodemographic characteristics, medical specialty preferences, and the impact of 31 factors on these choices such as interest in dealing with diverse patient issues, and the influence of physician role models among others. Statistical analysis performed using SPSS version 26.0 Descriptive statistics, including frequencies and percentages, were used to summarize participant demographics and medical specialty preferences. …”
Get full text

Isoacteoside alleviates hepatocellular carcinoma progression by inhibiting PDHB-mediated reprogramming of glucose metabolism by Lijun Zhao, Haonan Qi, Weiting Liu, Huiying Lv, Peixian Li, Wenyue Liu, Ruili Sun, Qiongzi Wang, Xiangpeng Wang

“…However, the specific impact of PDHB on hepatocellular carcinoma (HCC) metabolic reprogramming and its role in tumor progression remain to be elucidated. …”
Get full text

Inter-reader agreement for diagnosing thymic cysts on chest MRI in two tertiary referral centers by Yura Ahn, Sang Min Lee, Chu Hyun Kim, Sehee Kim, Jooae Choe, Joon Beom Seo, Ho Yun Lee

“…Abstract Despite the substantial role of chest MRI for the diagnosis and follow-up of thymic cysts, information about inter-reader agreement and optimal MR sequences is still limited. …”
Get full text

Enhanced vehicle routing for medical waste management via hybrid deep reinforcement learning and optimization algorithms by Norhan Khallaf, Osama Abd-El Rouf, Abeer D. Algarni, Mohy Hadhoud, Ahmed Kafafy

“…Modern technologies, particularly artificial intelligence, play a crucial role in improving medical waste management by developing intelligent systems that optimize the shortest routes for waste transport, from its generation to final disposal. …”
Get full text

Rice genotypes (Oryza sativa) respond to varying planting dates and environmental conditions by 1Asif Ali Kaleri, 1Danish Manzoor,1Rabia Laghari,2Muzamil Awan, 3Bina Khanzada, 4Hafsa Munir, 2Saba Solangi, 2Tameer Hyder Shah.5Ameer Jan, 6Laiba Ashfaq, 2Ghulam Sajjad Kaleri Kaleri

“… An essential food crop with a big role in the global economy is rice (Oryza sativa L.). …”
Get full text

Exploring benefits of speech and language therapy interventions for post-stroke aphasia rehabilitation: A qualitative study by Grace Larweh, Abena Asiedua Owusu Antwi, Ewurama Ampadu Owusu, Thomas Amatey Tagoe

“…Family members of people with aphasia valued speech and language interventions as it gave them the opportunity to play a significant role in the recovery process of their family members with aphasia. …”
Get full text

The Dutch-translated cultural competence assessment scale for nurses: Cross-cultural adaptation and validation by P.B. Sutharson, J.M. Maaskant, A.M. Eskes

“…As frontline caregivers, nurses play a key role in providing culturally-sensitive care. Measuring cultural competence can be challenging. …”
Get full text

Impact of resin tapping on the radial growth and climate sensitivity of naturally- regenerated Pinus roxburghii (Chir pine) in Western Nepal by Bipin Bhattarai, Narayan Prasad Gaire, Tek Maraseni, Bishnu Prasad Devkota, Badri Bhattarai, Shankar Tripathi, Kamal Raj Aryal, Hari Adhikari

“…Furthermore, both tapped and untapped trees exhibited a positive correlation between radial growth and temperatures in May, June, July and August suggesting critical role of temperature in influencing the growth of Pinus roxburghii trees whether they have been tapped for resin or not. …”
Get full text

Genomic characterization of chronic lymphocytic leukemia in patients of African ancestry by Cecilia Bonolo de Campos, Chantal E. McCabe, Laura A. Bruins, Daniel R. O’Brien, Sochilt Brown, Renee C. Tschumper, Cristine Allmer, Yuan Xiao Zhu, Kari G. Rabe, Sameer A. Parikh, Neil E. Kay, Huihuang Yan, James R. Cerhan, John N. Allan, Richard R. Furman, J. Brice Weinberg, Danielle M. Brander, Diane F. Jelinek, Marta Chesi, Susan L. Slager, Esteban Braggio

“…Furthermore, we found transcription enrichment of the Tumor Necrosis Factor-alpha (TNFα) Signaling via NF-κB pathway in AA CLL compared to EA CLL, suggesting that tumor promoting inflammation plays an important role in AA CLL. In summary, these results suggest that genomic instability and NF-kB activation is more prevalent in AA CLL than EA CLL.…”
Get full text

Fecal microbiota transplantation modulates jejunal host-microbiota interface in weanling piglets by Shankumar Mooyottu, Muhammed Shafeekh Muyyarikkandy, Farnaz Yousefi, Ganwu Li, Orhan Sahin, Eric Burrough, Joy Scaria, Brett Sponseller, Alejandro Ramirez

“…Prior FMT treatment in the context of ETEC infection indicated a potential protective role, as evidenced by a significant shift in microbial diversity and metabolomic compositions and decreased diarrhea severity even though no effect on pathogen shedding was evident. …”
Get full text

Cell-free osteoarthritis treatment with dual-engineered chondrocyte-targeted extracellular vesicles derived from mechanical loading primed mesenchymal stem cells by Peng Wang, Haiyue Zhao, Wei Chen, Yuhui Guo, Shuo Zhang, Xin Xing, Shuai Yang, Fengkun Wang, Juan Wang, Zengwu Shao, Yingze Zhang

“…In conclusion, this study underscores the critical role of mechanical loading in augmenting effectiveness of EVs in mitigating OA and introduces dual-engineered EVs that specifically target chondrocytes, providing a promising therapeutic strategy for OA.…”
Get full text

Protocol paper: randomized controlled trial of the smart online-to-offline model development for chronic diseases management through digital health in real world setting by Jae Eun Shin, Juho Choi, Heejung Lee, Suk-Won Lee, Juhwan Oh

“…Innovative digital health services have the potential to revolutionize chronic disease management by providing patients with real-time, personalized care and empowering them to take an active role in their health. There is a critical need to evaluate the effectiveness of such services. …”
Get full text

Mini Worldlit: A Dataset of Contemporary Fiction from 13 Countries, Nine Languages, and Five Continents by Andrew Piper, David Bamman, Christina Han, Jens Bjerring-Hansen, Hoyt Long, Itay Marienberg-Milikowsky, Tom McEnaney, Mathias Iroro Orhero, Emrah Peksoy, Pallavi Rastogi, Sebastian Rasmussen, Roel Smeets, Alexandra Stuart, Mads Rosendahl Thomsen

“…World literature plays a key role in understanding the global diversity of human storytelling. …”
Get full text

SkelETT—Skeleton-to-Emotion Transfer Transformer by Pedro Victor Vieira Paiva, Josue Junior Guimaraes Ramos, Marina Gavrilova, Marco Antonio Garcia de Carvalho

“…Emotion recognition plays an essential role in human-computer interaction, spanning diverse domains from human-robot communication and virtual reality to mental health assessment and affective computing. …”
Get full text

Bufalin targets the SRC-3/c-Myc pathway in chemoresistant cells to regulate metastasis induced by chemoresistance in colorectal cancer by Jinbao Chen, Chenqi Wu, Kun Yu, Jinpei Liu, Jiahua Yang, Wei Li, Xiaoxia Tang, Yihai Shi, Ke Xu, Yi Chen, Xiaoyu Qin

“…Bufalin has a therapeutic effect on both metastasis and drug resistance, but how bufalin affects chemoresistance-mediated metastasis remains unclear. Methods The role of BU in the inhibition of EMT and angiogenesis induced by chemoresistant cells using wound healing assays, invasion assays, HUVEC tube formation and adhesion assays. …”
Get full text

Transforming lemon Peel into a sustainable reservoir of bioactives: A green osmotic dehydration strategy by Priyanka Prajapati, Chhavi Porwal, Meenakshi Garg, Neha Singh, Susmita Dey Sadhu, Rajni Chopra, Eram S. Rao, Aparna Agarwal, Mohd Saeed, Safia Obaidur Rab, Dipendra Kumar Mahato, Pradeep Kumar, Madhu Kamle, Abhishek Dutt Tripathi

“…This study investigates the role of OD in stabilizing bioactive compounds in lemon peel, fostering sustainable citrus by-product applications. …”
Get full text

Gut Microbiota and Its Impact on Brain Function and Mental Health by Zofia Martyna Wójcik, Katarzyna Kamińska-Omasta, Bartosz Omasta, Olga Krupa, Paulina Dorota Pietrukaniec, Kuba Borys Romańczuk, Kinga Furtak, Szymon Przemysław Stolarczyk, Magdalena Agata Czerska, Daria Rybak

“…The intestinal microbiota is a complex ecosystem playing a crucial role in maintaining human homeostasis. It consists of billions of microorganisms, including bacteria, viruses, fungi, and archaea, which closely interact with their host. …”
Get full text

Gender beliefs and norms underlying intimate partner violence stigma among women living in Botswana: Results of an exploratory factor analysis. by Ari Ho-Foster, Mercilene Tanyaradzwa Machisa, Lorato Ruth Moalusi, Nicola Christofides

“…Gendered social norms may play an important role in understanding how survivors experience IPV stigma. …”
Get full text

Helicobacter pylori CagA+ strains modulate colorectal pathology by regulating intestinal flora by Shasha Cui, Xinqiang Liu, Fengxia Han, Lu Zhang, Jingjing Bu, Sainan Wu, Jiafen Wang

“…Abstract Aim This article aims to investigate the role of Helicobacter Pylori (HP) CagA+ strains affected colorectal lesion via gut microbiota. …”
Get full text

Single Nucleotide Polymorphisms, Associated with Increased Risk of Irritable Bowel Syndrome with Predominant Constipation: A Meta Analysis by E. A. Trush, A. E. Karchevskaya, R. V. Maslennikov, E. A. Poluektova, O. S. Shifrin, V. T. Ivashkin

“…Genetic predisposition in combination with environmental factors and the patient’s psychological and emotional state play a key role in the development of irritable bowel syndrome (IBS). …”
Get full text