Acid sphingomyelinase modulates anxiety-like behavior likely through toll-like receptor signaling pathway by Huiqi Yuan, Yanan Xu, Hailun Jiang, Meizhu Jiang, Luofei Zhang, Shifeng Wei, Cao Li, Zhigang Zhao

“…Abstract Recent studies have shown that abnormal activity of acid sphingomyelinase (Asm) has been associated with a range of psychiatric disorders including schizophrenia and depression. However, the role of Asm in the regulation of anxiety remains unclear. …”
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Maternal Serum Fractalkine Concentrations in Pregnancies Complicated by Fetal Growth Restriction by Ecem Berfun Toprak Sager, Ibrahim Kale, Hakan Sager, Aysegul Ozel, Murat Muhcu

“…Although there are a few studies examining the relationship between fractalkine and preeclampsia, its role in isolated fetal growth restriction has not been investigated yet. …”
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TEFM facilitates transition from RNA synthesis to DNA synthesis at H-strand replication origin of mtDNA by Shigeru Matsuda, Masunari Nakayama, Yura Do, Takashi Ishiuchi, Mikako Yagi, Sjoerd Wanrooij, Kazuto Nakada, Fan-Yan Wei, Kenji Ichiyanagi, Hiroyuki Sasaki, Dongchon Kang, Takehiro Yasukawa

“…Herein, we examine the role of mitochondrial transcription elongation factor (TEFM) in this process. …”
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Evolution of Multiple Launch Rocket Systems from Early Rockets to HIMARS and Beyond by Mykola Bondarenko, Volodymyr Habrinets, Mykhailo Vorobei

“…This study contributes to the theoretical understanding of MLRS in modern warfare, with a specific focus on HIMARS’ evolving role in shaping new military tactics and its integration into contemporary combat doctrine. …”
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SOCS2 inhibits the tumorigenesis of GISTs and increases the sensitivity of GISTs to imatinib by suppression of KIT activation by Liangying Zhang, Kun Xiao, Shaoting Zhang, Sien Zhao, Zimei Liu, Ming Wang, Kaiyue Qin, Yuanyuan Yu, Shujing Li, Lijun Ma, Jianmin Sun

“…Taken together, our data revealed the key role of SOCS2 in the tumorigenesis of GISTs and the sensitivity of GISTs to the targeted therapy, providing a better basis for the improved treatment strategy.…”
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The impact of empathy on professional identity among Chinese junior male nurses: a moderated mediation model by Hezi Mu, Hezi Mu, Yi Cui, Lihua Zhang, Qin Liu, Lanfang Zhang, Haoshuang Yang, Changchang Chen, Na Liu, Yinling Zhang

“…BackgroundNursing care is essential, but the role of junior male nurses in medical and health services is underestimated; thus, many junior male nurses leave the profession due to a lack of professional identity.ObjectiveThis study examined how the mediating effect of emotional intelligence and the moderating role of locomotion mode influence the relationship between empathy and professional identity among Chinese junior male nurses.MethodsThis cross-sectional descriptive study was conducted among junior male nurses in China from December 2021 to May 2022. …”
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Towards health justice: Implementing structural competency in women’s healthcare education by Daina Charnelle Fougang, Charles Mpofu, Dianne Wepa

“…Objectives: This systematic review aims to: (1) evaluate structural competency’s role in women’s health disparities and (2) develop implementation strategies for women’s healthcare education. …”
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Impact of geriatric nutritional risk index and diabetes mellitus on prognosis in ischaemic heart failure with reduced ejection fraction by Zhiyong Shi, Mingkai Yun, Haiyan Liu, Sijin Li, Xiaoli Zhang

“…Abstract It is unclear whether diabetes mellitus (DM) affects the role of malnutrition in heart failure (HF). We evaluated the effect of the geriatric nutritional risk index (GNRI) on HF prognosis and DM’s role in this relationship. …”
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Rural Development in Community Empowerment Through the Governance of Village-Owned Enterprises (BUMDES) by Sofyan Hadi, Auradian Marta, Raja Muhammad Amin, Rury Febrina

“… Sustainable national development is an important part of rural development that plays a role in empowering rural communities. In an effort to build Indonesia from villages, among others, village-owned enterprises are needed, which are supported by the legislation of Law Number 6 of 2014 concerning villages. …”
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The control of effective source rocks on the distribution of hydrocarbon reservoirs in a lacustrine rift-basin: insights from a 3D basin modeling study by Bang Zeng, Jianhua Qu, Zhongrong Mi, En Xie, Hui Fu, Sibo Yang, Yang Shi, Meijun Li

“…Effective source kitchens play a critical role in controlling hydrocarbon accumulation patterns, yet existing studies often rely on statistical methods limited by exploration biases. …”
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Microbial dysbiosis in periodontitis and peri-implantitis: pathogenesis, immune responses, and therapeutic by Ziwei Cui, Peng Wang, Weiyue Gao

“…An electronic and manual literature search was conducted using PubMed, Excerpta Medica, Frontiers Reports and the Wiley Online Library databases for relevant articles. Data from these publications were extracted and the overall findings were summarized in a narrative manner. …”
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Patients’ preferences on atopic dermatitis skincare and social media use: a qualitative study by Roxana Mazilu, Stefanie Ziehfreund, Stephan Traidl, Alexander Zink

“…Over-the-counter products play a crucial role in AD treatment. The emergence of social media (SM) as a vast information source for skincare and healthy lifestyle has transformed its role from mere entertainment. …”
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Effect of Local Simvastatin on the Healing of Surgically Created Critical-Sized Bone Defects: An experimental Study on sheep. by Rebin Azad Abdulsamad, Luqman Fawzi Omar

“… Background and objective: the role of simvastatin in lowering serum cholesterol levels is well described. …”
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New options for targeting TRPV1 receptors for cancer treatment: odorous Chinese herbal medicine by Minghui Zhang, Minghui Zhang, Zongao Wang, Zongao Wang, Shaojun Liu, Shaojun Liu, Yuxuan Li, Yuxuan Li, Yanting Gong, Yanting Gong, Min Liu, Min Liu

“…It is also involved in the process of cancer occurrence and progression, and researchers are revealing its role in cancer. In this paper, we review the expression and significance of TRPV1 receptor in various cancer cell types, the role of TRPV1 in the apoptosis-proliferation balance, cancer cell invasion and metastasis, and tumor micro-environment, with emphasis on the mechanisms by which TRPV1 receptor mediates inflammatory response, immune system, and thus regulates cancer. …”
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Detrimental effects of cadmium on male infertility: A review by Nebojša Zečević, Jovana Kocić, Milan Perović, Aleksandar Stojsavljević

“…Infertility has become a serious health and socio-economic-psychological problem globally. The harmful role of trace metals in male infertility is recognized but still not sufficiently explained. …”
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Omega-3 long chain fatty acids and their metabolites in pregnancy outcomes for the modulation of maternal inflammatory- associated causes of preterm delivery, chorioamnionitis and... by Jose Miguel Rizo, Theresa Steeb, Johanna Eiblwieser, Pedro Antonio Regidor

“…Additionally, we highlight the possible role of SPMs in the prevention of obstetric complications through oral supplementation using enriched marine oil nutritional’s. …”
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The Effect of Group Savings on the Household Welfare in Uganda: A Case Study of Bataka Abamwe Group in Butogota Town Council, Kanungu District. by Akancungura, Sheila

“…Both primary and secondary data collection tools were used with relevant tools like questionnaires to come up with the required data. …”
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The Contribution of Nongovernment Organisations in the Enhancement of The Social Economic Welfare of the Street Children: A Case Study of Lift up Jesus Child Development Center in... by Ntabangaryino, James

“…However, several church-founded and community-based organizations have played a significant role in rehabilitating street children to turn them into productive citizens. …”
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Effect of Poverty and Child Prostitution in Kamuganguzi Sub¬-county Kabale District. by Katusiime, Marvellous

“…The study was guided by three objectives which were: to find out the role poverty plays in child prostitution in the Kamuganguzi sub-county, to find out the causes of child engagement in prostitution in the Kamuganguzi sub-county, to explore the efforts made to combat Child Prostitution in Kamuganguzi sub-county. …”
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Relationship Between Attitudes, Academic Performance, Gender and Choice of Agricultural Careers Among Secondary School Students in Kanungu District Uganda. by Byaruhanga, Hillary

“…However, most respondents disagreed that experiential learning influenced their agricultural academic performance and career choice, with a mean score of 2.41 and a standard deviation of 1.082. The role of mentorship and positive role models was also assessed, with a mean score of 2.47 (SD = 0.922). …”
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