Genetic mechanisms of dynamic functional connectivity density in diabetic retinopathy brains: a combined transcriptomic and resting-state functional magnetic resonance imaging stud... by Yu-Lin Zhong, Hao Liu, Xin Huang

“…BackgroundDiabetic retinopathy (DR) is a condition characterized by fundus lesions resulting from retinal microvascular leakage and obstruction linked to chronic progressive diabetes mellitus. …”
Get full text

The impact of different optical treatment strategies on the dynamics of refraction after minimally invasive sclero-strengthening treatment of progressive myopia in children by G. A. Markosyan, E. P. Tarutta, E. N. Iomdina, V. N. Papyan, N. A. Tarasova, S. V. Milash, T. Yu. Larina, K. A. Ramazanova

“…The most effective treatment is a combination of MIS and optical correction with accommodation support and/or impact on peripheral retinal defocus. This approach to managing pediatric patients with progressive myopia should be a priority.…”
Get full text

Relative peripheral refractive errors in Chinese children with myopic anisometropia by Yu-Ting Tong, Yu-Qin Du, Shan-Shan Ge, Li Chen, Xiao-Qi Ma, Yu-Juan Guo, Yue-Hua Zhou

“…SER≥2.0 D group. In correlation analysis, ?TRDV, ?RDV 10-53, ?RDV-S, and ?RDV-N were negatively correlated with ?…”
Get full text

Field Massage as a Complementary Therapy to Phototherapy in Neonates with Hyperbilirubinemia by Rizki Amelia, Rachmawati Putri Motik, Hendra Hendra, Supriadi Supriadi, Joko Sapto Pramono, Jasmawati Jasmawati, Nursari Abdul Syukur, Siti Raihana, Ratna Wati, Rosalin Ariefah Putri, Panyada Cholsakhon

“…While phototherapy is the standard approach, it has limitations and potential side effects, such as diarrhea, dehydration, skin rashes, retinal damage, hyperthermia, extended hospital stays, maternal-infant separation, and disruptions in breastfeeding. …”
Get full text

Impact of Best Corrected Final Visual Acuity on the Performance of Intraocular Lens Power Calculations by Shammas HJ, Shammas MC, Bahr C, Sahota R, Hall B

“…Most of these patients are seniors and some of them present with concomitant retinal problems that limit the final visual acuity. …”
Get full text

Clinical Characteristics and Prognostic Factors of Patients with Intraocular Foreign Bodies from a Tertiary Eye Center in North China by Xing X, Liu F, Qi Y, Li J, Yu B, Wan L

“…Post-vitrectomy, three cases showed secondary macular membrane, five cases exhibited retinal detachment, and enucleation was necessary in three cases. …”
Get full text

Exploring Effects of Age at the Onset of Myopia on Multiple Diseases Using Electronic Health Records by Xiayin Zhang, PhD, Shan Wang, MD, Yu Huang, PhD, Yanjie Xie, PhD, Ishith Seth, MD, Gabriella Bulloch, MD, Chunran Lai, MD, Yijun Hu, PhD, Xianwen Shang, PhD, Mingguang He, PhD, Zhuoting Zhu, PhD, Honghua Yu, PhD

“…Eleven distinct disease associations with dose-response effects were confirmed using Cox proportional hazards analysis with stratified PRS. Two-sample MR analyses provided further support for the effects of younger age at myopia on higher risks of retinal detachments, cataracts, disorders of the vitreous body, and hypothyroidism, whereas older age of the onset of myopia conferred a higher risk of primary angle-closure glaucoma. …”
Get full text

Tumor infection with human herpes viruses and features of peripheral blood lymphocyte subset composition in patients with uveal melanoma by Elena V. Svetlova, N. V. Balatskaya, I. G. Kulikova, S. V. Saakyan, I. V. Svirina, A. E. Andryushin, E. B. Myakoshina

“…Co-infection with EBV and HHV-6 was detected in 1 case (retinal pigment epithelium adenocarcinoma). According to the PCR data, patients were divided into 2 groups based on tumor infectivity: Group 1 — HHV+ and Group 2 — HHV–. …”
Get full text

Comparative study of the vascular structures of the retina and choroid in Chinese Han and Uygur populations with proliferative diabetic retinopathy: An OCTA study by Yunxian Gao, Zhumahan Tuokedaerhan, Jie Zhang, Lei Yang, Yani Zhang, Wanying Cheng, Yong Zhao, Jiawei Wang

“…Methods: Fifty-three eyes of 53 healthy volunteers (25 from Hans and 28 from Uygurs) and 40 eyes of 40 PDR patients (20 from Hans and 20 from Uygurs) were included. Retinal and choroidal parameters, including thickness, vessel flow density (VFD), foveal avascular zone (FAZ) area, choroidal vascularity volume and index (CVV and CVI) were evaluated. …”
Get full text

Impact of horizontal and vertical posterior pole steepness on the dimensions of idiopathic macular hole by Niroj Kumar Sahoo, Jay Chhablani, Ashika Patil, Ninan Jacob, Mudit Tyagi, Srinivas Rao Podili, Rahman Khan Pathan

“…In an attempt to see if the curvature of the retinal pigment epithelium has any role, we aimed to analyse the influence of horizontal and vertical posterior pole steepness on idiopathic macular hole dimensions. …”
Get full text

Risk factors for venous thromboembolic events in patients with rheumatoid arthritis by M. A. Satybaldyeva, T. M. Reshetnyak, N. V. Seredavkina, S. I. Glukhova, D. E. Karateev, E. L. Nasonov

“…One patient was recorded to have upper extremity vein thrombosis and another had central retinal vein thrombosis. Lower extremity deep vein thrombosis was complicated by pulmonary thromboembolism in one case. …”
Get full text

Patient Knowledge of Risk Factors for Age-Related Macular Degeneration by Benjamin Sommer Thinggaard, Yousif Subhi, Jakob Grauslund, Lonny Stokholm

“…Among tobacco smokers, 73.0 % were aware of its potential contribution to nAMD, and 3.9 % had quit tobacco smoking due to their retinal diagnosis. Regarding physical inactivity, 10.8 % reported that they were informed of its potential contribution to nAMD, and 2.6 % had increased their physical activity due to nAMD. …”
Get full text

Di George syndrome: early diagnosis in pediatric practice by A. A. Pavlikov, I. M. Melnikova, T. I. Pakhomova, N. P. Myakin

“…Children with 22q11.2DS have a high incidence of ophthalmologic pathology: astigmatism (50%), retinal angiopathy (20%), iris coloboma (5%), and strabismus (15%).Conclusion. …”
Get full text

Outcomes of 25-Gauge Vitrectomy for Tractional and Nontractional Diabetic Macular Edema with Proliferative Diabetic Retinopathy by Hideaki Someya, Kei Takayama, Masaru Takeuchi, Hiroshi Yokoyama, Takeshi Kimura, Masakazu Morioka, Yoshihiro Takamura, Seiji Sameshima, Tetsuo Ueda, Nahoko Ogata, Maki Tashiro, Shigehiko Kitano, Taiji Sakamoto

“…Multiple linear regression analysis showed that baseline VA and CMT in the TME group and kidney function in the nTME group were the predictable factors of the 12-month postoperative VA. …”
Get full text

Using Serum Metabolomic Signatures to Investigate Effects of Acupuncture on Pain-Fatigue-Sleep Disturbance in Breast Cancer Survivors by Hongjin Li, Ardith Z. Doorenbos, Yinglin Xia, Jun Sun, Hannah Choi, Richard E. Harris, Shuang Gao, Katy Sullivan, Judith M. Schlaeger

“…Mixed-effects models adjusting for covariates (age, race, body mass index, and antidepressant use) were applied for analysis. Results: After acupuncture, there was a significant reduction in the psychoneurological symptom cluster (mean reduction = −6.2, <i>p</i> < 0.001).Bonferroni correction was applied to 40 independent metabolite clusters (α = 0.00125); cysteine-glutathione disulfide (<i>p</i> = 0.0006) significantly increased, and retinal (<i>p</i> = 0.0002) and cis-urocanate (<i>p</i> = 0.0005) were significantly decreased. …”
Get full text

Quantitative autofluorescence is increased in clinically unaffected fellow eyes from patients with posterior uveitis by Robert P. Finger, Julie Jungblut, Marie D. Just, Jan H. Terheyden, Frank G. Holz, Raffael Liegl, Thomas Ach, Maximilian W. M. Wintergerst

“…As these changes may precede future inflammation in yet unaffected eyes, additional longitudinal studies including analysis of eyes with active disease are warranted.…”
Get full text

Clinical innovation research model for fundus diseases: 6 elements, 3 ones by WEN Feng, ZHANG Xiongze, LI Miaoling, GAN Yuhong, SU Yongyue

“…This model emphasizes: 1) identifying a single abnormal case during routine fundus evaluation; 2) systematically expanding this observation into a case series through case accumulation, feature extraction, literature review, and comparative analysis; and 3) ultimately proposing or refining novel disease entities or manifestations through critical thinking and innovation. …”
Get full text

Real-ambient PM2.5 induced corneal epithelial barrier disruption through Wnt/β-catenin signaling by Jiayin Sun, Yanting Li, Haowen Chen, Linfei Chen, Shuhan Tian, Lin Lu, Jinglong Tang, Yuxin Zheng, Mingliang Zhang, Xiaoya Ji

Get full text

Severe Joubert syndrome in family with homozygous POC1B p.Arg106Pro variant is due to a co-inherited deep-intronic mutation in the neighboring CEP290 gene by Christian Betz, Björn Reusch, Thomas Langmann, Sandra Habbig, Bodo B. Beck, Hanno J. Bolz

“…We have previously reported a family with severe, mostly early-lethal Joubert syndrome (JBTS) with early-onset severe retinal dystrophy (EOSRD) and polycystic kidney disease (PKD), which at that time had been attributed to a homozygous pathogenic missense variant, p.Arg106Pro (c.317G>C), in the ciliary POC1B gene. …”
Get full text

Pathogenetic Justification of a New View on the Treatment of Angle-Closure Glaucoma by N. A. Bakunina, L. N. Kolesnikova, J. M. Salmasi, L. M. Balashova

“…The thickness of RNFL (Retinal nerve fiber layer, structural parameter) decreased due to a decrease in edema in 1–2 groups, slightly increased in 3–4 groups, in our opinion, due to improved blood circulation. …”
Get full text