The perspective of ceRNA regulation of circadian rhythm on choroidal neovascularization by Ying Yang, Shu Su, Jia Chen, Xiaowei Yang, Shenglai Zhang, Aimin Sang

“…Abstract Abnormal growth of blood vessels (choroidal neovascularization) can lead to age-related macular degeneration (AMD) and eventually cause vision loss due to detachment of the retinal pigmented epithelium. This indicates that choroidal neovascularization is important for the treatment of AMD. …”
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Faricimab for treatment-resistant choroidal neovascularization (CNV) in neovascular age-related macular degeneration (nAMD): seven-months results using artificial intelligence and... by Anna Heinke, Alexandra Warter, Ines D. Nagel, Akshay Agnihotri, Nehal Nailesh Mehta, Carlo Miguel B. Galang, Daniel N. Deussen, Dirk-Uwe G. Bartsch, Lingyun Cheng, Henry A. Ferreyra, William R. Freeman

“…AI-assisted software analysis showed a significant reduction of IRF, SRF, and PED volume at multiple time points after initiating faricimab. …”
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Fundoscopy as a diagnostic biomarker in idiopathic normal pressure hydrocephalus: a pilot study by Sune Munthe, Frantz Rom Poulsen, Mathias Just Nortvig, Niclas Lynge Eriksen, Mikkel C Schou Andersen, Emma Tubæk Nielsen, Christian Bonde Pedersen

“…Receiver operating characteristic curve analysis with an area under the curve of 0.75 showed a sensitivity of 88% and a specificity of 50% with an A/V cut-off of 0.86. …”
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Structural insights into light-gating of potassium-selective channelrhodopsin by Takefumi Morizumi, Kyumhyuk Kim, Hai Li, Probal Nag, Tal Dogon, Oleg A. Sineshchekov, Yumei Wang, Leonid S. Brown, Songhwan Hwang, Han Sun, Ana-Nicoleta Bondar, Igor Schapiro, Elena G. Govorunova, John L. Spudich, Oliver P. Ernst

“…Upon photoisomerization of the retinal chromophore, the retinylidene Schiff base NH-bond reorients from the extracellular to the cytoplasmic side. …”
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Effective Diabetic Retinopathy Classification With Siamese Neural Network: A Strategy for Small Dataset Challenges by Maria Tariq, Vasile Palade, Yingliang Ma

“…Furthermore, we conduct an in-depth analysis of hyperparameter optimisation, specifically investigating different pair selection techniques, loss functions, and distance layers to thoroughly evaluate their impact on the performance of the model. …”
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Relationship between macular microvasculature and visual function in idiopathic macular epiretinal membrane by using OCT angiography and multifocal electroretinogram by Haiyue Xu, Yu Wang, Bo Zou, Meilin Liu, Chunmeng Dai, Yuchen Zheng, Xiaoxia Ding

“…Results: BCVA, central retinal thickness (CRT) and parafoveal vessel density (PFVD) of the deep capillary plexus (DCP) changed significantly 3 months after surgery. …”
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Anti-TNFα and Anti-IL-1β Monoclonal Antibodies Preserve BV-2 Microglial Homeostasis Under Hypoxia by Mitigating Inflammatory Reactivity and ATF4/MAPK-Mediated Apoptosis by Linglin Zhang, Chaoqiang Guan, Sudena Wang, Norbert Pfeiffer, Franz H. Grus

“…The disruption of microglial homeostasis and cytokine release are critical for neuroinflammation post-injury and strongly implicated in retinal neurodegenerative diseases like glaucoma. …”
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Vogt-Koyanagi-Harada syndrome potentially associated with COVID-19 vaccination: a case report and literature review by Zhiqiang Cui, Yan Luo, Yanli Yi, Xuli Guo, Yuqi Liu, Xiang Wang, Xiaonan Liu

“…The patient presented with bilateral blurred vision 14 days post-vaccination, diagnosed as VKH with retinal neuroepithelial detachment via fluorescein angiography (FFA) and optical coherence tomography (OCT). …”
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Visual impairment prevention by early detection of diabetic retinopathy based on stacked auto-encoder by Shagufta Almas, Fazli Wahid, Sikandar Ali, Ahmed Alkhyyat, Kamran Ullah, Jawad Khan, Youngmoon Lee

“…Leveraging a comprehensive dataset from KAGGLE containing 35,126 retinal fundus images representing one healthy (normal) stage and four DR stages, our proposed model demonstrates superior accuracy compared to existing deep learning algorithms. …”
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Ophthalmologic examination and ocular ultrasound of the south american coati (Nasua nasua) by Anita Marchionatti Pigatto, Guilherme Rech Cassanego, Carolina Cauduro da Rosa, Jean Carlos Gasparotto, Luiza Tonietto Mangini, Gabriella De Nardin Peixoto, Natália Karianne Brandenburg, Luís Felipe Dutra Corrêa, Alexandre Krause

“…The values obtained for CCT and US are not previously available in the literature, and together with STT, IOP and retinal pattern, can be used as reference for the species.…”
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Effect of Ocular Hypertension on D-β-Aspartic Acid-Containing Proteins in the Retinas of Rats by Takashi Kanamoto, Takashi Tachibana, Yasushi Kitaoka, Toshio Hisatomi, Yasuhiro Ikeda, Yusuke Murakami, Kei Tobiume, Ryo Asaoka, Yoshiaki Kiuchi

“…To investigate the effect of ocular hypertension-induced isomerization of aspartic acid in retinal proteins. Methods. Adult Wistar rats with ocular hypertension were used as an experimental model. …”
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Asxl1 regulates optic cup development through interaction with Lhx2 and epigenetic modulation of Wnt signaling by Seungtae Moon, Nackhyuong Kim, A-Reum Kim, Kyeong Hwan Moon, Jin Woo Kim, Soo-Jong Um

“…In further investigation using isolated cell from E10.5 retinal region, neuroepithelial stem cells from Asxl1 KO embryos exhibited impaired proliferation and spheroid formation. …”
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Intravitreal bevacizumab for neovascular age-related macular degeneration by Junn R. Pajarillo, MD, Harvey S. Uy,MD, Milagros H. Arroyo MD, MPH

“…Results: Thirty eyes (15 per group) were included in the final analysis. Both treatment and control groups were comparable in baseline characteristics. …”
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Lack of strong evidence for cone photoreceptors’ contribution to human melatonin suppression and alerting response to light by Fatemeh Fazlali, Rafael Lazar, Faady Yahya, Christian Epple, Manuel Spitschan, Oliver Stefani, Christian Cajochen

“…Summary: Light exposure at night can suppress melatonin production and increase alertness, primarily through the action of melanopsin-containing intrinsically photosensitive retinal ganglion cells (ipRGCs). This study investigated whether cone photoreceptors also influence melatonin suppression and subjective alertness using non-visual metameric light. …”
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Effect of modified surgical conditions on the peripapillary microvasculature and RNFL in patients receiving vitrectomy: an OCTA study by Ting Pan, Cunxin Bian, Yuan Fang, Jingfan Wang, Yidan Xu, Ping Xie, Zizhong Hu

“…Fisher’s exact test, the Mann-Whitney U test, t test, and repeated-measures analysis of variance (RM-ANOVA) were used to analyze our data. …”
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Correlating 10-2 Visual Field Loss with Structural and Angiographic Parameters in Advanced Glaucoma by Kübra Atay Dinçer, Metehan Karaatlı, Onur Özalp, Tülay Şimşek, Monisha Esther Nongpiur, Eray Atalay

“…Abstract Introduction We investigated the relationship between optical coherence tomography (OCT) angiography (OCTA)-derived vascular parameters, central visual field (10-2 VF), ganglion cell complex (GCC), and retinal nerve fiber layer (RNFL) thickness in patients with advanced glaucoma. …”
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Incidence and risk factors of cataract following pediatric pars plana vitrectomy by Antoine Bourgeois, Thibaut Chapron, Ismael Chehaibou, Florence Metge, Youssef Abdelmassih, Georges Caputo

“…Overall, the risk of developing cataract after PPV increased from 21% at 1 year to 47% at 5 years The factor associated with the development of postoperative cataract were the need for multiple surgeries (58.8% vs. 13.6%, p < 0.001), the type of tamponade used p < 0.001), older age at surgery (101.9 ± 53.1 months vs. 71.0 ± 60.8 months, p < 0.001), and retinal detachment (78.8% vs. 19.1%, p < 0.001). Multivariate analysis including the aforementioned variables identified the need for multiple surgeries [OR: 2.7 (CI: 1.2–6.2), p = 0.02)] as a risk factor for the development post-PPV cataract while the use of air or no tamponade as protective (p = 0.001). …”
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Risk Factors for Glaucoma Suspicion in Healthy Young Asian and Caucasian Americans by E. Lauren Doss, Linden Doss, Ying Han, Susan Huang, Travis Porco, Melike Pekmezci, Shan Lin

“…Regression analysis showed race affected spherical equivalent (P<0.001), AL (P=0.0073), IOP (P<0.001), and cup to disc area ratio (CDAR) (P=0.012). …”
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Visual Functions in Children in Remote Postoperative Period after Laser Treatment of Threshold Stages of Retinopathy of Prematurity by M. V. Pshenichnov, O. V. Kolenko, V. V. Egorov, E. L. Sorokin

“…Purpose. Analysis of visual functions in children in remote postoperative period after laser coagulation (LC) of threshold stages of retinopathy of prematurity (ROP).Patients and methods. …”
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Effects of dapagliflozin on blood volume status and vascular outcomes in clinically stabilized heart failure patients after an acute decompensated heart failure event (DAPA-VOLVO s... by Konstantinos Bitos, Natallia Laptseva, Thomas Haider, Valentina A Rossi, Matthias P Nägele, Jens Barthelmes, Frank Ruschitzka, Isabella Sudano, Andreas J Flammer

“…Secondary outcomes include differences between the two study groups regarding blood volume profile, micro- and macro-vascular function assessed by retinal vessel analysis and flow-mediated vasodilation, respectively, changes in body water distribution, quality of life, exercise capacity, echocardiographic and laboratory parameters.…”
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