Two cases of type I sialidosis and a literature review by Yuan Ding, Ming Cheng, Chunxiu Gong

“…Conclusion NEU1 gene analysis provides essential guidance for genetic counseling and prenatal diagnosis. …”
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Alterations in ganglion cell and nerve fiber layer in Leber hereditary optic neuropathy across clinical stages by Michael Oeverhaus, Mareile Knetsch, Ying Chen, Leyla Jabbarli, Carmen Nolden, Anja Eckstein, Nikolaos E. Bechrakis, Philipp Rating

“…However, chronic patients exhibited significantly reduced the retinal nerve fiber layer (RNFL), especially in the temporal region (32 μm vs. 56 μm, p < 0.0001), but not in the nasal region. …”
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Success predictors of selective laser trabeculoplasty in primary angle-closure glaucoma: a long-term follow-up by N. I. Kurysheva, L. V. Lepeshkina, E. O. Shatalova

“…The predictors of SLT failure were common for both forms of glaucoma in Cox regression analysis, namely: initial IOP &gt; 24 mm Hg (OR = 1.184, p = 0.029 for PACG and OR = 1.156, p = 0.010 for POAG), corneal hysteresis &lt; 9,5 mm Hg (OR = 1.441, р = 0.022 for PACG and OR = 1.486, р = 0.030 for POAG), corneal thickness &lt; 540 μm (OR = 1.586, р=0.021 for PACG and OR =1.648, p =0.030 for POAG), reduced thickness of the retinal nerve fiber layer &lt; 90 μm (OR = 1.231, p = 0.014 for PACG and OR =1.194, p = 0.027 for POAG) and age &gt; 68 years (OR = 1.162, p = 0.040 for PACG and OR = 1.167, p = 0.000 for POAG). …”
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Histone Deacetylase 6 (HDAC6) in Ciliopathies: Emerging Insights and Therapeutic Implications by Zhiyi Wang, Xiaofan Zhu, Zhenzhou Huang, Kaidi Ren, Jie Ran, Yang Yang

“…The therapeutic potential of HDAC6 inhibitors has been explored, with promising results in various disease models, including retinal and renal ciliopathies, highlighting their ability to restore normal ciliary function. …”
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Ceruloplasmin replacement therapy ameliorates neurological symptoms in a preclinical model of aceruloplasminemia by Alan Zanardi, Antonio Conti, Marco Cremonesi, Patrizia D'Adamo, Enrica Gilberti, Pietro Apostoli, Carlo Vittorio Cannistraci, Alberto Piperno, Samuel David, Massimo Alessio

“…Iron deposition promotes diabetes, retinal degeneration, and progressive neurodegeneration. …”
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Guidelines for glaucoma imaging classification, annotation, and quality control for artificial intelligence applications by Wei-Hua Yang, Yan-Wu Xu, Xing-Huai Sun, Expert Workgroup of Guidelines for Glaucoma Imaging Classification, Annotation, and Quality Control for Artificial Intelligence Applications

“…CFP is primarily used for the annotation of the optic cup and disc, while OCT is used for measuring and annotating the thickness of the retinal nerve fiber layer, and AS-OCT and UBM focus on the annotation of the anterior chamber angle structure and the measurement of anterior segment structural parameters. …”
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Transient ocular hypertension remodels astrocytes through S100B. by Weiran Huang, Kenji Matsushita, Rumi Kawashima, Susumu Hara, Yuichi Yasukura, Kaito Yamaguchi, Shinichi Usui, Koichi Baba, Andrew J Quantock, Kohji Nishida

“…Here, we investigated the morphology of retinal and optic nerve head (ONH) astrocytes under mechanical stress, and explored whether a specific phase is present that precedes astrocyte remodeling. …”
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Neurophysiological Changes in Patients with Discirculatory Encephalopathy Associated with Ischemic Optic Neuropathy by T. N. Iureva, A. A. Zaika, V. V. Shprakh, S. I. Zhukova

“…To conduct a comparative analysis of changes in neurophysiological parameters of the brain and visual analyzer in patients with dyscirculatory encephalopathy and patients with a combination of dyscirculatory encephalopathy and ischemic optic neuropathy. …”
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Predictive modeling of rapid glaucoma progression based on systemic data from electronic medical records by Richul Oh, Hyunjoong Kim, Tae-Woo Kim, Eun Ji Lee

“…Abstract This study investigated the baseline systemic features that predict rapid thinning of the retinal nerve fiber layer (RNFL) in patients with primary open-angle glaucoma (POAG). …”
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Novel mTORC2/HSPB4 Interaction: Role and Regulation of HSPB4 T148 Phosphorylation by Zachary B. Sluzala, Yang Shan, Lynda Elghazi, Emilio L. Cárdenas, Angelina Hamati, Amanda L. Garner, Patrice E. Fort

“…We recently demonstrated that this phosphorylation is reduced in retinal tissues from patients with diabetic retinopathy, raising the question of its regulation during diseases. …”
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Optical Coherent Tomography-Angiography in the Research of Myopia Complicated by Choroidal Neovascularization by E. A. Drozdova, O. V. Zhiliaeva

“…A prospective study of 25 people (40 eyes) with complicated myopia was carried out, which consisted in a comparative analysis of the qualitative and quantitative OCTA characteristics of 29 eyes with myopic CNV and 11 paired intact eyes. …”
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Bruch´s membrane thickness in relationship to axial length. by Hai Xia Bai, Ying Mao, Ling Shen, Xiao Lin Xu, Fei Gao, Zhi Bao Zhang, Bin Li, Jost B Jonas

“…<h4>Purpose</h4>To assess a potential role of Bruch´s membrane (BM) in the biomechanics of the eye, we measured its thickness and the density of retinal pigment epithelium (RPE) cells in various ocular regions in eyes of varying axial length.…”
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Tetra-anionic porphyrin mimics protein-protein interactions between regulatory particles and the catalytic core, allosterically activating human 20S proteasome by A. M. Santoro, M. Persico, A. D’Urso, A. Cunsolo, O. Tkachuk, D. Milardi, R. Purrello, G. R. Tundo, D. Sbardella, P. A. Osmulski, M. Gaczynska, M. Coletta, C. Fattorusso

“…Decreased proteasome activity is a hallmark of brain and retinal neurodegenerative diseases (Alzheimer’s, Parkinson’s diseases, glaucoma) boosting the search for molecules acting as proteasome activators. …”
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Aggressive Posterior Retinopathy of Prematurity (APROP): LASER as the Primary Modality of Treatment by Shilpi H Narnaware, Prashant K Bawankule, Dhananjay Raje

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Eye vascular hemodynamics in patients with anterior ischemic optic neuropathy after surgery with application of the Alloplant biomaterial by V. U. Galimova, I. V. Verzakova, Z. Kh. Karimova, E. M. Gareev

“…According to cluster analysis there were four typological groups of cases, characterized by originality of RI changes in all six vessels in general.Results: The diagrams show that significant intergroup differences in postoperative RI changes occurred in the medial and lateral branches of short posterior ciliary artery. …”
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Correlation between Nephropathy and Ophthalmic Complications in Cases of Sickle Cell Anemia: An Entangled Association by Aditi Pareek, Aditya Khandekar, Sourya Acharya, Pravin Tidake, Samarth Shukla

“…Proliferative and non-proliferative retinal changes can also occur, due to similar underlying pathophysiology of vasospasm. …”
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Pediatric Nonaccidental Trauma: Experience at a Level 1 Trauma Center by Taylor Goldman, Sathyaprasad Burjonrappa

“…Facial, torso, lower extremity, retinal, and internal organ injury were significantly more common with NAT. …”
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Identifying facilitators, barriers and areas of opportunity in diabetic retinopathy screening: quality improvement through qualitative methods by Senxi Du, Matthew Freeby, Maria Han, Sylvia Lambrechts

“…Barriers included competing demands, distant retinal camera locations, limited appointment access and financial and insurance issues. …”
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High-resolution optical coherence tomography in pigmented choroidal lesions by Damian Jaggi, Shalin G. Aeberhard, Dmitri Artemiev, Martin S. Zinkernagel, Florian M. Heussen

“…Results 32 of the 40 subjects could be included in the image analysis, the rest were excluded due to insufficient imaging. …”
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Baicalin prevents experimental autoimmune uveitis by promoting macrophage polarization balance through inhibiting the HIF-1α signaling pathway by Bin Liu, Yuan Peng, Congling Wang, Huixia Wei, Shuqin Xu, Yunfeng Liu, Xuewei Yin, Hongsheng Bi, Dadong Guo

“…Histopathological analysis confirmed reduced inflammatory cell infiltration in the ciliary body and retina. …”
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