Multi-omics and experimental validation studies reveal key biomarkers of cellular senescence in diabetic retinopathy by Jinju Li, Hao Yang, Yixuan Lin, Zhaohui Fang

“…The characteristic gene set for DR-CS was obtained by intersecting differentially expressed genes (DEGs), Weighted Gene Co-expression Network Analysis (WGCNA) results, and CSRGs. Subsequent analyses involved constructing protein-protein interaction (PPI) network, cytoHubba screening, enrichment analysis, and immune infiltration analysis. …”
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Baseline characteristics associated with the first year treatment interval of intravitreal faricimab in neovascular age-related macular degeneration (nAMD) by Sobha Sivaprasad, Philippe Margaron, Aachal Kotecha, Thibaud Mathis, Parth Shah, Neala Rafijah, Yannan Tang

“…While this analysis provides insights for treatment intervals during the first year, further analysis incorporating Y2 data from the TENAYA and LUCERNE studies will be needed to assess factors influencing treatment intervals over a longer period.…”
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Epidemiological Studies on Eye Diseases in Centers for Stray Dogs in Northwestern Romania by Elena Bonea, Cornel Dionisie Igna, Monica Ocnean, Bianca Cornelia Lungu, Ioan Hutu

“…Additionally, the dogs were grouped by sterilization status and gender. The statistical analysis was performed using Pearson’s chi-squared test, Student’s <i>t</i>-test, and binary logistic regression. …”
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Phase I Study of the Anti-interleukin 33 Fragment Antigen-Binding Region RO7303359 in Geographic Atrophy Secondary to Age-Related Macular Degeneration by Joel A. Pearlman, MD, PhD, Veeral S. Sheth, MD, MBA, Arshad M. Khanani, MD, MA, Vahan B. Indjeian, PhD, Flavia Brunstein, MD, PhD, Denison Kuruvilla, PhD, Mauricio Maia, PhD, Randall Dere, Ling Ma, PhD, Hao Chen, PhD, Seema Datta, PhD, Jeffrey R. Willis, MD, PhD, Henry E. Wiley, MD

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Systemic Effects of Intravitreal Anti-VEGF Therapy: A Review of Safety across Organ Systems by Mousumi Banerjee, Sikshya Moharana, Srikanta Kumar Padhy

“…Abstract Intravitreal anti-vascular endothelial growth factor (anti-VEGF) therapies have transformed the management of retinal diseases such as diabetic macular edema and neovascular age-related macular degeneration. …”
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Reliability of OCT Assisted RNFL Thickness In Diagnosing Glaucoma In High Myopia by Neha Yadav, Aanshu Sahai, Raj Kumar Sharma, Mohd. Abid Shamshad, Salani Gupta, Yamni Singhal

“…Material And Methods: This is a cross-sectional study to compare retinal nerve fibre layer thickness (RNFL) in 112 eyes of 56 subjects presenting to our centre from May 2017 to March 2018. …”
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Ophthalmic hypertension in patients after vitreoretinal surgery with various tamponades of the vitreal cavity by S. N. Akulov, E. V. Kabardina, N. S. Bronnikova

“…We analyzed 344 case histories of patients aged 30 to 80 who underwent vitreoretinal intervention with various tamponades of the vitreal cavity for macular rupture, epiretinal membrane, hemophthalmia, retinal detachment in 2019–2021. To detect ophthalmic hypertension, all patients underwent tonometry before surgery and every month after it during the entire 2-year follow-up period.Results. …”
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Visual Subfield Progression in Glaucoma Subtypes by Wei-Wen Su, Shian-Sen Hsieh, Shih-Tsung Cheng, Cheng-Wen Su, Wei-Chi Wu, Henry Shen-Lih Chen

“…The raw data of the 30-2 Humphrey Field Analyzer from glaucoma patients with definite visual field progression were processed with pointwise linear regression (PLR) analysis. The rate of change of retinal threshold sensitivity in the ten glaucoma hemifield test (GHT) zones, the upper and the lower hemifields, and the whole field was evaluated and was correlated with patients’ basic demographic data. …”
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The transcription factor Jun is necessary for optic nerve regeneration in larval zebrafish. by Sarah C Sarich, Virinchipuram S Sreevidya, Ava J Udvadia, Kurt R Svoboda, Jennifer H Gutzman

“…Induction of dominant negative Jun downregulated endogenous jun expression and larvae with functional jun knockdown demonstrated impaired retinal ganglion cell axon regeneration. Analysis of select putative Jun target genes, previously shown to be upregulated in adult zebrafish optic nerve regeneration, demonstrated that with functional Jun knockdown, atf3 and ascl1a were significantly downregulated, and sox11a was upregulated at distinct time points. …”
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Optic Disc Oedema: Presentation and Causes at a Tertiary Centre in North Karnataka by Raghavendra Ijeri, R.C. Jyoti

“…Other investigations like blood examination, Visual field analysis and radiological investigations like Computed Tomography scans and Magnetic Resonance Imaging were done when required. …”
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Identification of diabetic retinopathy lesions in fundus images by integrating CNN and vision mamba models. by Zenglei Liu, Ailian Gao, Hui Sheng, Xueling Wang

“…Diabetic retinopathy, a retinal disorder resulting from diabetes mellitus, is a prominent cause of visual degradation and loss among the global population. …”
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Heidelberg retina tomography II parameters in evaluating high- and normal-pressure glaucoma progression by Risović Dušica, Gvozdenović Ranko, Marjanović Ivan, Abazi Zihret, Stamenković Miroslav

“…Both segmental and global scanning is of importance in glaucoma progression analysis.…”
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In Vivo Imaging of Cobalt-Induced Ocular Toxicity in a Mouse Model by Basel Obied, Galit Saar, Stephen Richard, Ygal Rotenstreich, Ifat Sher, Alon Zahavi, Nitza Goldenberg-Cohen

“…Optic nerve analysis demonstrated myelin loss and increased inflammation with high levels of reactive gliosis. …”
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Medical and technical aspects of using intraocular lenses with extended depth of field by M. E. Konovalov, A. V. Morenko

“…The duration of the retrospective analysis was 7 years (2016–2022), some of the considered work dates back to 2023. …”
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Comparison of anatomical visual features of the eyeball, lens, and retina the diurnal common kestrel (Falco tinnunculus rupicilaeformis) and the nocturnal little owl (Athene noctua... by Walaa Shalaby, Ramadan Kandyel, Mohamed Abumandour, Fawzyah A. Al-Ghamdi, Doaa Gewily

“…There were significant differences in the retinal layer thickness between the two raptors, in which the diurnal kestrel had a thinner pigmented epithelium and photoreceptor layers compared to the nocturnal owl. …”
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Engrafted human induced pluripotent stem cell-derived anterior specified neural progenitors protect the rat crushed optic nerve. by Leila Satarian, Mohammad Javan, Sahar Kiani, Maryam Hajikaram, Javad Mirnajafi-Zadeh, Hossein Baharvand

“…<h4>Background</h4>Degeneration of retinal ganglion cells (RGCs) is a common occurrence in several eye diseases. …”
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Macular curvature in vertical cross sections of optical coherence tomography in school age children by Masaya Yamaguchi, Takehiro Yamashita, Ryo Asaoka, Hiroto Terasaki, Naoya Yoshihara, Naoko Kakiuchi, Taiji Sakamoto

“…Axial length, color fundus photographs, and optical coherence tomographic vertical cross-sectional images of the macula were obtained and used for analysis. The macular curvature was plotted as the retinal pigment epithelium and fitted to a second-degree polynomial equation using ImageJ software, to calculate the macular curvature. …”
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Comparison of In Vivo Gene Expression Profiling of RPE/Choroid following Intravitreal Injection of Dexamethasone and Triamcinolone Acetonide by Zeljka Smit-McBride, Elad Moisseiev, Sara P. Modjtahedi, David G. Telander, Leonard M. Hjelmeland, Lawrence S. Morse

“…The data were analyzed using GeneSpring GX 12.5 and Ingenuity Pathway Analysis (IPA) microarray analysis software for biologically relevant changes. …”
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Corneal Endothelial Cell Changes Associated with Multiple Intravitreal Injections by Mariaelena Malvasi, Pietro Mangiantini, Floriana Testa, Edoardo Trovato Battagliola, Mattia D’Andrea, Guglielmo Minozzi, Paolo Turchetti, Elena Pacella

“…These variables were analyzed using multiple linear regression analysis. Results: A total of 108 diseased eyes were treated with a variable number (from 4 to 28) of intravitreal injections between January 2020 and December 2023. …”
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Peripapillary Nerve Fiber Layer Thickness and Optic Nerve Head Parameters in Patients Recovered from COVID-19: A Longitudinal Study by Mojtaba Abrishami, Kiana Hassanpour, SeyedehMaryam Hosseini, Nasser Shoeibi, Mohammad Reza Ansari-Astaneh, Zahra Emamverdian, Bahareh Gharib, Nasibeh Amini, Majid Abrishami

“…To quantify the longitudinal changes of the optic nerve head (ONH) parameters and peripapillary retinal nerve fiber layer (pRNFL) thickness in patients recovered from coronavirus disease 2019 (COVID-19) using spectral-domain optical coherence tomography (OCT) analysis. …”
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