Applying a New Automated Perimetry Pattern Based on the Stimulus Distribution of the Multifocal ERG to Improve Structure-Function Investigation in Glaucoma by Lívia M. Brandão, Matthias Monhart, Andreas Schötzau, Anna A. Ledolter, Anja M. Palmowski-Wolfe

“…The results of both (mean defect (MD) and mean sensitivity (MS)) were compared with optical coherence tomography (OCT): retinal nerve fiber layer (RNFL) thickness, macular thickness (mT), and ganglion cell analysis (GCIPL). …”
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Risk factors of diabetic nephropathy with retinopathy by Liang Dong-rui, Li Xiao-dong, Fu Yan, Chai Feng-ting, Li Bao-xin

“…ObjectiveTo explore the risk factors and relationship of diabetic nephropathy （DN） with diabetic retinopathy （DR）.MethodsBetween January 2017 and January 2021，type 2 DN patients were divided into DN &amp; retinal group （observation，<italic>n</italic>=160） and DN &amp; non-retinal group （control，<italic>n</italic>=90）.General profiles and clinical parameters of two groups were compared.Binary Logistic regression statistical method was employed for variables with statistical differences.ResultsWhen observation and control groups were compared，systolic pressure （SBP），cystatin C （Cys C），LDL-C，HbA1C，24 h urethral protein （24 Upro） and serum uric acid （SUA） were higher and the difference was statistically significant （<italic>P</italic>&lt;0.01）.For variables with statistical differences，binary Logistic regression analysis indicated that Cys C，HbA1C and 24 Upro were independently correlated in observation group （<italic>P</italic>&lt;0.05）.ConclusionThe independent risk factors of DN patients with retinopathy include Cys C&gt;1.0 mg/L （<italic>OR</italic> 1.556，95%<italic>CI</italic>1.125-1.783），HbA1C（%） &gt;8.0 <italic>OR</italic> 1.545，95%<italic>CI</italic>（1.114-2.234） and 24 h Upro &gt;3.0g （<italic>OR</italic> 1.569，95%<italic>CI</italic>（1.227-2.256）.Early measures of diagnosis and treatment should be implemented for improving the survival and prognosis of DN patients.…”
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Osteopontin and Other Regulators of Angiogenesis and Fibrogenesis in the Vitreous from Patients with Proliferative Vitreoretinal Disorders by Ahmed M. Abu El-Asrar, Mohd Imtiaz Nawaz, Dustan Kangave, Mohammed Mairaj Siddiquei, Karel Geboes

“…Exploratory logistic regression analysis identified significant associations between PDR and high levels of HMGB1, CTGF and PEDF, between PDR with active neovascularization and high levels of CTGF and PEDF, and between PDR with traction retinal detachment and high levels of HMGB1. …”
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A Color Doppler Imaging Study of Ocular Haemodynamic Parameters in Normal Tension Glaucoma by Atif Rahman Raini, Humayoun Ashraf, Mohd Ashraf, Mohd Khalid, Ziya Siddiqui, Mohd Maroof

“…Statistical Analysis: Mean, standard deviation (SD) and Independent t-test was applied. …”
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Association between smoking history and optical coherence tomography angiography findings in diabetic patients without diabetic retinopathy. by Dong-Wei Liu, Zeeshan Haq, Daphne Yang, Jay M Stewart

“…<h4>Purpose</h4>To investigate any associations between cigarette smoking and retinal microvascular changes in diabetic patients without visible retinopathy.…”
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Cytomegalovirus uveitis in HIV-infected patients: course and outcomes by T. D. Sizova, V. M. Khokkanen, D. A. Gusev, E. V. Boyko

“…Petersburg Center for the Prevention and Control of AIDS and Infectious Diseases and at the Department of Ophthalmology of North-Western State Medical University named after I.I. Mechnikov. The analysis of statistical data of HIV Newsletters in St. …”
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Human expert grading versus automated quantification of fluid volumes in nAMD, DME and BRVO by Felix Goldbach, Bianca S. Gerendas, Oliver Leingang, Thomas Alten, Alexandros Bampoulidis, Jonas Brugger, Hrvoje Bogunovic, Amir Sadeghipour, Ursula Schmidt-Erfurth

“…Abstract This study compared an automated deep learning algorithm with certified human graders from the Vienna Reading Center (VRC) in identifying intra- (IRF) and subretinal fluid (SRF) in OCT scans of patients treated for neovascular age-related macular degeneration (nAMD), diabetic macular edema (DME) and branch retinal vein occlusion (BRVO). Multicenter clinical trial data from the VRC imaging database was used for this post hoc analysis. …”
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Effectiveness of Feature Extraction by PCA-Based Detection and Naive Bayes Classifier for Glaucoma Images by J. Shiny Christobel, D. Vimala, J. Joshan Athanesious, S. Christopher Ezhil Singh, Sivaraj Murugan

“…After cataract, glaucoma is one of the second leading retinal diseases in the world. This paper presents the methodology to detect the glaucoma using principal component analysis. …”
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Sequencing of Pax6 loci from the elephant shark reveals a family of Pax6 genes in vertebrate genomes, forged by ancient duplications and divergences. by Vydianathan Ravi, Shipra Bhatia, Philippe Gautier, Felix Loosli, Boon-Hui Tay, Alice Tay, Emma Murdoch, Pedro Coutinho, Veronica van Heyningen, Sydney Brenner, Byrappa Venkatesh, Dirk A Kleinjan

“…We show that the paired-less Pax6.2 ortholog in zebrafish is expressed specifically in the developing retina. Transgenic analysis of elephant shark and zebrafish Pax6.2 CNEs with homology to the mouse NRE/Pα internal promoter revealed highly specific retinal expression. …”
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Genotype-Phenotype Characterization of Novel Variants in Six Italian Patients with Familial Exudative Vitreoretinopathy by Giancarlo Iarossi, Matteo Bertelli, Paolo Enrico Maltese, Elena Gusson, Giorgio Marchini, Alice Bruson, Sabrina Benedetti, Sabrina Volpetti, Gino Catena, Luca Buzzonetti, Lucia Ziccardi

“…Eight probands (age range 7–19 years) were assessed by genetic analysis and comprehensive age-appropriate ophthalmic examination. …”
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<i>Atp1b2^Atp1b1</i> Knock-In Mice Exhibit a Cone–Rod Dystrophy-Like Phenotype by Susanne Bartsch, Yevgeniya Atiskova, Stefanie Schlichting, Elke Becker, Maike Herrmann, Udo Bartsch

“…We have previously shown that <i>Atp1b2</i> knock-out (ko) mice exhibit rapid photoreceptor cell degeneration, whereas <i>Atp1b2^Atp1b1</i> knock-in (ki) mice, which express the β1-subunit instead of the β2-subunit under regulatory elements of the <i>Atp1b2</i> gene, exhibit slowly progressive retinal dystrophy. Here, we performed a detailed analysis of the retinal phenotype of the <i>Atp1b2^Atp1b1</i> ki mouse. …”
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Inflammatory bowel disease and risk of ophthalmic inflammation-related diseases: a two-sample Mendelian randomization study by Shao-Jie Ren, Ting Liu, Man-Hong Xu, Wei Shi, Xiao-Rong Li

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One-year experience with latanoprostene bunod ophthalmic solution 0.024% in clinical practice: A retrospective observational study. by Chun-Mei Hsueh, Chen-Hsin Tsai, Jou-Chen Huang, Si-Huei Lee, Tsung-Jen Wang, Siao-Pei Guo

“…Subgroup analysis with glaucoma types and PGA use were performed for additional IOP reduction after LBN use.…”
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Pharmacological mydriasis in patients with type 2 diabetes. A comparative study among different levels of diabetic retinopathy by Felipe Bekman Rocha, Nadyr Antonia Damasceno, Luziane Herzog de Azeredo Ramalho, Adroaldo de Alencar Costa Filho, Marcio Penha Morterá Rodrigues, Maria Luiza Gois da Fonseca, Raphael Boechat, Rubens Antunes da Cruz Filho, Eduardo de França Damasceno

“…Vertical and horizontal pupillary diameter were measured. Analysis of variance test F, Student's t-test and Chi-squared were used for the statistical analysis. …”
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Home-monitoring/remote optical coherence tomography in teleophthalmology in patients with eye disorders—a systematic review by Joanna Dolar-Szczasny, Agnieszka Drab, Robert Rejdak

“…Scan times were faster when conducted at home compared to those in the office.ConclusionHome/remote OCT devices can effectively provide diagnostic-grade retinal imaging outside traditional settings. High diagnostic accuracy was demonstrated compared to in-office OCT. …”
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Non-Invasive Diagnosis of Polypoidal Choroidal Vasculopathy as a Variant of the Course of Age-Related Macular Degeneration by I. E. Panova, T. B. Shaimov, V. A. Shaimova

“…In 11 cases (68.8%) the nodules were associated with hemorrhage and in 14 cases (87.5%) — with hard yellowish exudates. Comparative analysis of retinal anatomy allowed for defining typical OCT signs of PCV that distinguish the clinical entity from type 1 and 2 choroidal neovascular membranes: neurosensory retinal detachment in the parafovea (80.0%, p &lt; 0.001) and hard exudates (71.9%, p &lt; 0.001). …”
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Acute Vascular Pathology of the Eye as a Complication of the Past COVID-19 Infection. Clinical Observations by T. V. Gavrilova, A. P. Sergienko, M. V. Chereshneva

“…In the second presented case, we observed the development of an acute ischemic circulatory disorder of the retina of the left eye (thrombosis of the central retinal vein) 2.5 months after the onset of the disease with a new coronavirus infection. …”
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Surgical treatment of macular hole without removal of the internal limiting membrane by A.Yu. Kleimenov, V.N. Kazaikin, М.А. Lipina, A.D. Ozhegov

“…Throughout the entire observation period, there was no negative dynamics in the state of the retinal ganglion cell complex relative to the indicators of the normative base. …”
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Integrating non-linear radon transformation for diabetic retinopathy grading by Farida Mohsen, Samir Belhaouari, Zubair Shah

“…Current automatic grading methods rely heavily on deep learning applied to retinal fundus images, but the complex, irregular patterns of lesions in these images, which vary in shape and distribution, make it difficult to capture the subtle changes. …”
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Improving the conditions of regional hemodinamics of the eyes as a method of treatment in optic neuropathy at short-sightedness of high degree. by N. G. Zavgorodnyaya, O. O. Denisova, N. A. Vesnina, N. A. Kudinova- Savchenko

“…Analyzing the performance of retinal tomography HRT II for the reporting period in the study group noted the absence of further thinning of the nerve fibers. …”
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