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901
Graph-Aware Multimodal Deep Learning for Classification of Diabetic Retinopathy Images
Published 2025-01-01“…Traditional diagnostic methods primarily rely on single-modality data, such as retinal images, or the analysis of image features, which may limit diagnostic accuracy. …”
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902
Prevalence and risk factors of hypertensive retinopathy in South Korea based on national health survey data
Published 2025-07-01“…Future research should explore retinal image analysis and longitudinal datasets to enhance early detection and clarify the systemic implications of hypertensive retinopathy.…”
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903
Exploitation of enhanced prime editing for blocking aberrant angiogenesis
Published 2025-06-01“…Results: NILVs targeting VEGFR2 delivered into cultured murine vascular endothelial cells led to 51.06 % VEGFR2 T17967A in the genome analyzed by next generation sequencing and the production of DN-VEGFR2, which was found to hamper VEGF-induced VEGFR2 phosphorylation, as demonstrated by Western blot analysis. Intravitreally injection of the dual NILVs into postnatal day 12 mice in a model of oxygen-induced retinopathy, led to production of retinal DN-VEGFR2 in postnatal day 17 mice which blocked retinal VEGFR2 expression and activation as well as abnormal retinal angiogenesis without interfering with retinal structure and function, as assessed by electroretinography, optical coherence tomography, fundus fluorescein angiography and histology. …”
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904
Temporal evolution and factors influencing visual function and RNFL thickness in ethambutol-associated optic neuropathy
Published 2025-04-01“…Macular ganglion cell-inner plexiform layer (mGCIPL) thickness showed a decreasing trend (73.20 ± 4.76 μm to 55.33 ± 4.16 μm) from 1 month post-onset. Multivariate analysis revealed that disease course was the primary factor influencing VF recovery (β = − 0.31, p = 0.001), while peripapillary retinal nerve fiber layer thinning was associated with gender, ethambutol dosage, and disease duration. …”
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905
Predictive model of small choroidal melanoma progression after eye-saving treatment based on clinical, morphometric and immunological parameters
Published 2022-03-01“…Selection of variables for this model was based on assessment of significant differences between the groups with chorio-retinal scar (n = 14) and residual tumor and/or continued tumor growth (n = 17).Multivariate analysis with conditional exclusion of variables revealed prognostic significance with four markers: morphometric, i.e., disorganization of the pigment in retinal pigment epithelium – Z1 (rs = 0.455); immunological, increased blood serum concentration of hepatocyte growth factor (HGF) – Z2 (rs = 0.377); level of pro-inflammatory chemokine RANTES – Z3 (rs = 0.362), content of transforming growth factor (TGF-2â) – Z4 (rs = 0.431). …”
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906
Adaptation optimizes sensory encoding for future stimuli.
Published 2025-01-01“…We then asked whether this characteristic change in encoding accuracy is predicted by the temporal statistics of natural visual input. Analyzing the retinal input of freely behaving human subjects showed that the distribution of local visual orientations in the retinal input stream indeed peaks at the mean orientation of the preceding input history (i.e., the adaptor). …”
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907
Retina Modeling by Artificial Neural Networks
Published 2024-03-01“…This approach is motivated by the resemblance between the behavior of the model and that of retinal cells. The neural network receives as input the intensity of light that is incident onto the retina and produces as output the activity of the retinal ganglion cells. …”
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908
Structural-Functional Correlation in Non-Arteritic Acute Ischemic Optic Neuropathy
Published 2025-05-01“…At three months post-presentation, patients underwent follow-up assessments comprising visual acuity testing, perimetry, and advanced retinal imaging.Results: During the acute phase, affected eyes demonstrated increased mean retinal nerve fiber layer (RNFL) thickness, while ganglion cell-inner plexiform layer (GCIPL) thickness decreased. …”
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909
Targeting glial fibrillary acidic protein in glaucoma: a monoclonal antibody approach to modulate glial reactivity and neuroinflammation for neuroprotection
Published 2025-06-01“…Retinal ganglion cell (RGC) survival and glial responses were evaluated with immunostaining. …”
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910
Identification of Patients with Pentosan Polysulfate Sodium-Associated Maculopathy through Screening of the Electronic Medical Record at an Academic Center
Published 2020-01-01“…Results. 216 charts were included for analysis, of which 96 had documented eye exams and 24 had retinal imaging done. …”
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911
PBN (Phenyl-N-Tert-Butylnitrone)-Derivatives Are Effective in Slowing the Visual Cycle and Rhodopsin Regeneration and in Protecting the Retina from Light-Induced Damage.
Published 2015-01-01“…A2E and related toxic molecules are part of lipofuscin found in the retinal pigment epithelial (RPE) cells in eyes affected by Stargardt's disease, age-related macular degeneration (AMD), and other retinal degenerations. …”
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912
Peripapillary microperimetry and optical coherence tomography angiography in patients with optic disc edema
Published 2025-04-01“…Peripapillary microperimetry was done to evaluate peripapillary retinal sensitivity. The different groups were compared with analysis of all data. …”
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913
Retinoblastoma Morphology after Local Chemotherapy
Published 2021-10-01“…Hemorrhagic changes associated with focal necrosis of the central retinal vessels (n = 4), destructive changes in retinal pigment epithelium (RPE; n = 10) associated with the accumulation of melphalan in RPE leading to atrophic processes in the retina. …”
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914
Optical coherence tomography angiography in non-alcoholic fatty liver disease: is it a disease affecting the microvascular system??
Published 2025-05-01“…Macular thickness (MT) and peripapillary retinal nerve fibre layer (pRNFL) thickness were assessed. …”
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915
Modern Aspects of Hypertensive Angioretinopathy
Published 2019-01-01“…Particular attention is paid to the clinical disease characteristics at the present stage with the analysis of the arterio-venous ratio, optic nerve edema (with high blood pressure figures) using an automated system, vector analysis, suggesting a new arteriovenous classification, called Web Integration (Wivern). …”
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916
Trends in myopia prevalence among late adolescents in South Korea: a population-level study and future projections up to 2050
Published 2024-12-01“…Retinal detachment was significantly more common among those with high myopia, while retinal dystrophy was less common.Conclusion This study highlights a concerning trend of increasing myopia and high myopia prevalence, which is likely to reach 90.90% and 31.26% by 2050, with significant future burden for public health and society.…”
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917
From Image to Sequence: Exploring Vision Transformers for Optical Coherence Tomography Classification
Published 2025-06-01“…Background: Optical coherence tomography (OCT) is a pivotal imaging technique for the early detection and management of critical retinal diseases, notably diabetic macular edema and age-related macular degeneration. …”
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918
Optimization of Platelet-Rich Plasma Fraction Selection for Surgical Treatment of Macular Holes
Published 2023-12-01“…Objective: based on clinical and morpho — functional analysis of retinal restoration and assessment of the cellular composition of platelet-rich plasma, to determine its optimal fraction for surgical treatment of macular hole. …”
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919
A multicenter study on rates and risk factors of proliferative vitreoretinopathy in a low-income economy.
Published 2025-01-01“…<h4>Objective</h4>To assess the rate and identify risk factors for proliferative vitreoretinopathy (PVR) in Nigerian patients with rhegmatogenous retinal detachment (RRD).<h4>Methods and analysis</h4>Multicenter, prospective, cross-sectional study of consecutive RRD patients attending four ophthalmic clinics, recruited over a period of twelve months. …”
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