Early peripapillary neurovascular injury and its relevant systemic factors in type 2 diabetic patients without retinopathy: An OCTA based study by Haochen Jin, Kaiyue Wang, Changhong Ren, Shan He, Yuan Gao, Xiaofang Liang, Xuxiang Zhang

“…Quantitative analysis of radial peripapillary capillary (RPC) density and peripapillary retinal nerve fiber layer (p-RNFL) thickness was automatically performed using the device's software, with segmentation of retinal regions into intra-optic disc and peripapillary zones. …”
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Glucose-Sensing Carbohydrate Response Element-Binding Protein in the Pathogenesis of Diabetic Retinopathy by Christopher R. Starr, Assylbek Zhylkibayev, Oleg Gorbatyuk, Alli M. Nuotio-Antar, James Mobley, Maria B. Grant, Marina Gorbatyuk

“…These mice underwent retinal functional testing, which was followed by proteomic analysis using LC-MS. …”
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New correlations between ocular parameters and disease severity in Spanish patients with Gaucher's disease Type I. by Olivia Esteban, Miguel Angel Torralba, Susana Olivera, Mireya Martinez, Paula Montes, Sara Marco, Javier Ascaso

“…Complete ophthalmological examination included choroidal and retinal thickness maps with swept source optical coherence tomography. …”
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The influence of renal function on surgical outcomes of vitrectomy in patients with proliferative diabetic retinopathy by Qiongzhen Yuan, Zhouquan Yang, Wei Fan, Xiaofan Chen, Huan Zou, Rongdi Yuan

“…No significant between-group differences were observed in the proportion of cataract surgery (p = 0.722), intraoperative retinal photocoagulation (p = 0.476), gas tamponade (p = 0.932), silicone oil tamponade (p = 0.254), retinal dialysis and/or iatrogenic retinal breaks (p = 0.447), and 23- or 25-gauge (G) microincision vitrectomy surgery (MIVS) (p = 0.160). …”
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Advanced Diabetic Retinopathy Detection with the R–CNN: A Unified Visual Health Solution by Sravya Valluri Sri, Srinivasu Parvathaneni Naga, Shafi Jana, Hołubowski Waldemar, Zielonka Adam

“…Our goal is to develop an automated, cost-effective method for identifying diabetic retinal disease specimens. This study introduces a faster R-CNN method for detecting and classifying DR lesions in retinal images. …”
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Exploring a Novel Hypothesis: Could the Eye Function as a Radar or Ultrasound Device in Depth and Distance Perception? Neurophysiological Insights by Hüseyin Findik, Muhammet Kaim, Feyzahan Uzun, Ayhan Kanat, Osman Nuri Keleş, Mehmet Dumlu Aydin

“…Results: Histological examination revealed significant similarities between retinal morphology and radar/ultrasound systems. The outermost retinal layer resembled an acoustic lens, with underlying layers functioning as acoustic matching layers. …”
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Interpretable multimodal classification for age-related macular degeneration diagnosis. by Carla Vairetti, Sebastián Maldonado, Loreto Cuitino, Cristhian A Urzua

“…We analyze the XAI methods in terms of their ability to identify retinal damage and ease of interpretation, concluding that grad-CAM and guided grad-CAM can be combined to have both a coarse visual justification and a fine-grained analysis of the retinal layers. …”
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The impact of corneal epithelial remodeling on visual quality after SMILE and FS-LASIK for high myopia by Yunjing Ma, Qi Li, Qian Guo, Yue Huang, Ruibo Yang, Hui Liu, Chen Zhang, Shaozhen Zhao

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Optical Coherence Tomography in the Diagnosis of Open-angle Glaucoma by Yu. N. Yusef, E. E. Kazaryan

“…The need for non-invasive methods of assessing the ocular vasculature has led to the development of OCT-angiography (OCT-A), which provides information on the state of both the retinal structure and its vascular bed through blood flow analysis, further increasing the value of this imaging method compared to conventional OCT. …”
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Etiopathogenesis of non-exudative age-related macular degeneration (literature review) by M. M. Bikbov, T. A. Khalimov

“…It is noted that the development of AMD may be associated with an age-related decrease in the level of estrogen in women. The analysis of the data on the etiopathogenesis of age-related macular degeneration presented in the modern literature indicates the need for further research and generalization of local and general pathological processes developing in the dynamics of retinal visual function disorders by specialists of various scientific disciplines.…”
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Swept Source Optical Coherence Tomography - Visualizing Vitreous, Retina and Choroid Simultaneously by Amit Gadkar, Vinod Kumar, Ruchir Tewari

“…It gives in vivo images of retina that can be correlated with histopathological analysis. Up to two thirds of blood supply of eye is derived from choroid. …”
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Topographic associations of hyperreflective materials in diabetic retinopathy: a multimodal correlation with microvascular pathology, structural remodeling and systemic metabolic d... by Lan Zhou, Lan Zhou, Hongyan Sun, Hongyan Sun, Cunzi Li, Cunzi Li, Tianyi Luo, Tianyi Luo, Ting Meng, Xiaojun Wen, Zilin Chen, Yan Hu, Ming-Ming Yang, Ming-Ming Yang

“…HRMs were systematically classified via multimodal optical coherence tomography angiography (OCTA) analysis, incorporating topographic localization (inner vs. outer retinal), reflectivity profiles, morphometric dimensions, posterior shadowing artifacts, and decorrelation signal. …”
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Orbital mesenchymal chondrosarcoma and its specific fusion gene HEY1-NCOA2 by Jia-Qi Lin, Xun Liu, Jin-Zhi Zhao, Qing Wang, Li-Min Zhu, Ting-Ting Lin

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Multifocal Electroretinography in Assessment of Macular Function after Internal Limiting Membrane Peeling in Macular Hole Surgery by M. Y. Faria, D. C. Sousa, S. Mano, R. Marques, N. P. Ferreira, A. Fonseca

“…In macular hole surgery, structure analysis in OCT is one of the important outcomes for the retinal surgeon. …”
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Profile of Macular Ganglion Cell-inner Plexiform Layer Thickness in Diabetics With and Without Retinopathy by Nimisha Kaushal, Neha C. Guliani, Brahm P. Guliani

“…At present, there is emerging evidence to suggest that retinal neurodegeneration is an early event in the pathogenesis of diabetic retinopathy (DR). …”
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Association of dietary inflammatory index and refractive status in American adolescents: NHANES 1999–2008 by Xiaodong Chen, Xiaodong Chen, Xiaodong Chen, Xuewei Li, Xuewei Li, Xuewei Li, Xuewei Li, Ningda Xu, Ningda Xu, Ningda Xu, Ningda Xu, Jiarui Li, Jiarui Li, Jiarui Li, Qianwen Guo, Qianwen Guo, Qianwen Guo, Heng Miao, Heng Miao, Heng Miao, Kai Wang, Kai Wang, Kai Wang, Kai Wang, Lvzhen Huang, Lvzhen Huang, Lvzhen Huang

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A machine learning model for predicting anatomical response to Anti-VEGF therapy in diabetic macular edema by Wenrui Lu, Kunhong Xiao, Xuemei Zhang, Yuqing Wang, Wenbin Chen, Xierong Wang, Yunxi Ye, Yan Lou, Li Li

“…Model performance was evaluated using accuracy, sensitivity, specificity, Area Under the Receiver Operating Characteristic Curve (AUC), and decision curve analysis. The best-performing model was further interpreted using SHAP analysis, and a nomogram was constructed for clinical application.ResultsAmong the 37 baseline variables, five key predictors were identified: preoperative CRT >400 μm, presence of retinal edema, presence of subretinal fluid (SRF), disorganization of the inner retinal layers (DRIL), and ellipsoid zone (EZ) integrity. …”
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Differences in macular structure and microvasculature between high myopia and non-high myopia by Qin Chen, Keyao Song, Qing Cun, Wenyan Yang, Yijin Tao, Hua Zhong, Shitou Lv, Chaoxu Qian, Chaoxu Qian

“…RT measurements revealed substantial increases in HM eyes, including total foveal (276.4 ± 36.1 μm vs. 250.1 ± 23.3 μm; p < 0.01), parafoveal (348.0 ± 23.0 μm vs. 329.7 ± 20.8 μm; p < 0.01), and perifoveal regions (304.9 ± 25.1 μm vs. 290.6 ± 15.5 μm; p < 0.01). Retinal vascular analysis showed reduced SRVD in the fovea with borderline significance (14.9 ± 7.1% vs. 17.9 ± 7.4%; p = 0.05), while DRVD showed a non-significant reduction (31.4 ± 10.1% vs. 37.8 ± 24.0%; p > 0.05). …”
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Role of Circulatory Hypoxia in the Development of Retinopathy of Prematurity by E. I. Sidorenko, G. V. Nikolaeva, E. E. Sidorenko

“…The  study included: indirect ophthalmoscopy; digital retinoscopy; calibrometry of retinal vessels; dopplerography;  analysis of partial pressure of oxygen and carbon dioxide in the  capillary blood. …”
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Retained introns in phototransduction genes of 5xFAD mouse retina suggest vision impairment as an early diagnostic marker for Alzheimer’s disease by Hyun-Min Lee, Jinho Kim, Ji-Young Kim, Mi-Jin An, Geun-Seup Shin, Ah-Ra Jo, Yuna Park, Chul-Hong Kim, Yujeong Hwangbo, Ju-Hyun Lee, Tae Kyung Hong, Kun Ho Lee, Sangmyung Rhee, Jung-Woong Kim

“…Herein, we identified genome-wide dysfunction of alternative splicing in the early stage of 5xFAD transgenic mouse retina by performing RNA sequencing analysis. Notably, retained introns, highly enriched in phototransduction and retinal genes in the 1.5-month-old 5xFAD mouse retina, was significantly associated with physiological impairment of rod photoreceptors in the retina, as evidenced by electroretinogram (ERG) analysis. …”
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